1188-21-2 | N-Acetyl-L-leucine

Packsize	Purity	Availability	Price	Discounted Price
25g	95%	in stock	$8.00	$5.00
100g	95%	in stock	$25.00	$17.00

Description

• Catalog Number: AB46681
• Chemical Name: N-Acetyl-L-leucine
• CAS Number: 1188-21-2
• Molecular Formula: C8H15NO3
• Molecular Weight: 173.2096
• MDL Number: MFCD00065131
• SMILES: CC(C[C@@H](C(=O)O)NC(=O)C)C
• NSC Number: 758152

Computed Properties

• Complexity: 177
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 0.5

Literature

• Urinary metabonomics study on biochemical changes in an experimental model of chronic renal failure by adenine based on UPLC Q-TOF/MS.

  Clinica chimica acta; international journal of clinical chemistry 20120322

• Biomarker discovery in biological specimens (plasma, hair, liver and kidney) of diabetic mice based upon metabolite profiling using ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry.

  Clinica chimica acta; international journal of clinical chemistry 20110512

• Ergodicity and efficiency of cross-polarization in NMR of static solids.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20110401

• Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3.

  The Biochemical journal 20101201

• On the performance of spin diffusion NMR techniques in oriented solids: prospects for resonance assignments and distance measurements from separated local field experiments.

  The journal of physical chemistry. B 20101104

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Sensitivity enhancement of separated local field experiments: application to membrane proteins.

  The journal of physical chemistry. B 20100422

• Sensitivity enhanced heteronuclear correlation spectroscopy in multidimensional solid-state NMR of oriented systems via chemical shift coherences.

  Journal of the American Chemical Society 20100421

• Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.

  Biochemistry 20090714

• Sensitivity enhancement in static solid-state NMR experiments via single- and multiple-quantum dipolar coherences.

  Journal of the American Chemical Society 20090429

• Effects of acetyl-DL-leucine in vestibular patients: a clinical study following neurotomy and labyrinthectomy.

  Audiology & neuro-otology 20090101

• Mismatched Hartmann-Hahn conditions cause proton-mediated intermolecular magnetization transfer between dilute low-spin nuclei in NMR of static solids.

  Journal of the American Chemical Society 20080827

• Shiftless nuclear magnetic resonance spectroscopy.

  The Journal of chemical physics 20080207

• Effects of vestibular training on motion sickness, nystagmus, and subjective vertical.

  Journal of vestibular research : equilibrium & orientation 20070101

• Application of Maximum Entropy reconstruction to PISEMA spectra.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060301

• A 'magic sandwich' pulse sequence with reduced offset dependence for high-resolution separated local field spectroscopy.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030901

• In vitro effects of acetyl-DL-leucine (tanganil) on central vestibular neurons and vestibulo-ocular networks of the guinea-pig.

  The European journal of neuroscience 20010201

• Autoradiography in brain of Macaca fascicularis monkeys after injection of acetyl-DL-leucine [2-14C] (Tanganil).

  European journal of drug metabolism and pharmacokinetics 20010101