119-68-6 | N-Methylanthranilic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	99%	in stock	$14.00	$10.00
5g	99%	in stock	$17.00	$12.00
10g	99%	in stock	$21.00	$15.00
25g	99%	in stock	$30.00	$21.00

Description

• Catalog Number: AA32195
• Chemical Name: N-Methylanthranilic acid
• CAS Number: 119-68-6
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.1626
• MDL Number: MFCD02668743
• SMILES: CNc1ccccc1C(=O)O
• NSC Number: 3782

Computed Properties

• Complexity: 147
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 2

Upstream Synthesis Route

2-(Methylamino)benzoic acid, also known as o-toluidinecarboxylic acid, is a versatile compound widely used in chemical synthesis. This compound is particularly valued for its role as a building block in the creation of various organic compounds due to its unique structure and reactivity.In chemical synthesis, 2-(Methylamino)benzoic acid serves as a crucial intermediate in the production of pharmaceuticals, agrochemicals, dyes, and other fine chemicals. Its acyl group can undergo acylation reactions to introduce specific functional groups, allowing for the fabrication of complex molecules with desired properties.Furthermore, the presence of the methylamino group provides opportunities for further derivatization through various chemical transformations such as substitution, oxidation, and reduction reactions. This versatility in chemical reactivity makes 2-(Methylamino)benzoic acid a valuable tool for organic chemists seeking to create novel compounds with specific properties.Overall, the application of 2-(Methylamino)benzoic acid in chemical synthesis is essential for the development of new materials, pharmaceuticals, and other products that contribute to advancements in science and technology.

Literature

• Novel internally quenched fluorogenic substrates for angiotensin I-converting enzyme and carboxypeptidase Y.

  Biomedical research (Tokyo, Japan) 20111201

• Quinolones: from antibiotics to autoinducers.

  FEMS microbiology reviews 20110301

• 3-Hy-droxy-1-methyl-2-[4-(piperidin-1-yl)phen-yl]quinolin-4(1H)-one.

  Acta crystallographica. Section E, Structure reports online 20110301

• Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.

  PloS one 20110101

• Chaperone-like N-methyl peptide inhibitors of polyglutamine aggregation.

  Biochemistry 20100824

• 2-Methyl-amino-5-nitro-benzoic acid.

  Acta crystallographica. Section E, Structure reports online 20100601

• Effects of prenatal exposure to a 50-Hz magnetic field on one-trial passive avoidance learning in 1-day-old chicks.

  Bioelectromagnetics 20100201

• The chick as a model for the study of the cellular mechanisms and potential therapies for Alzheimer's disease.

  International journal of Alzheimer's disease 20100101

• An investigation of the inclusion complex of cyclomaltoheptaose (beta-cyclodextrin) with N-methylanthranilic acid in the solid state.

  Carbohydrate research 20091214

• Tetra-kis[μ-4-(methyl-amino)-benzoato-κO:O']bis-[(N,N-diethyl-nicotinamide-N)zinc(II)] dihydrate.

  Acta crystallographica. Section E, Structure reports online 20091101

• Bis(isonicotinamide-κN)bis-[4-(methyl-amino)benzoato]zinc(II) monohydrate.

  Acta crystallographica. Section E, Structure reports online 20091101

• 2-(Methoxy-carbon-yl)anilinium dihydrogen phosphate.

  Acta crystallographica. Section E, Structure reports online 20090801

• Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20090405

• Bis[4-(methyl-amino)benzoato-κO]bis-(nicotinamide-κN)zinc(II).

  Acta crystallographica. Section E, Structure reports online 20090101

• Unusually divergent 4-coumarate:CoA-ligases from Ruta graveolens L.

  Plant molecular biology 20080701

• Aposematic colouration enhances memory formation in domestic chicks trained in a weak passive avoidance learning paradigm.

  Brain research bulletin 20080615

• Inhibitors of pathogen intercellular signals as selective anti-infective compounds.

  PLoS pathogens 20070901

• A role for eukaryotic translation initiation factor 2B (eIF2B) in taste memory consolidation and in thermal control establishment during the critical period for sensory development.

  Developmental neurobiology 20070501

• Passive avoidance training is correlated with decreased cell proliferation in the chick hippocampus.

  The European journal of neuroscience 20061101

• Enhancement of long-term memory retention by Colostrinin in one-day-old chicks trained on a weak passive avoidance learning paradigm.

  Neurobiology of learning and memory 20060701

• The biosynthesis and regulation of biosynthesis of Concord grape fruit esters, including 'foxy' methylanthranilate.

  The Plant journal : for cell and molecular biology 20051101

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Fluorescent ligands for the histamine H2 receptor: synthesis and preliminary characterization.

  Bioorganic & medicinal chemistry 20041215

• Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-methylthio-3-substituted quinazolin-4-(3H)-ones.

  Biological & pharmaceutical bulletin 20040501

• Inhibiting effect of D1, but not D2 antagonist administered to the striatum on retention of passive avoidance in the chick.

  Neurobiology of learning and memory 20040301

• Cyclin S: a new member of the cyclin family plays a role in long-term memory.

  The European journal of neuroscience 20040101

• Targeting malaria with polyamines.

  Bioconjugate chemistry 20040101

• Discriminative taste aversion learning: a learning task for older chickens.

  Neurobiology of learning and memory 20030101

• Triterpenoid constituents of Raulinoa echinata.

  Journal of natural products 20020401

• Amino acid release from the intermediate medial hyperstriatum ventrale (IMHV) of day-old chicks following a one-trial passive avoidance task.

  Neurobiology of learning and memory 20020301