1193-54-0 | 3,4-Dichloro-1H-pyrrole-2,5-dione

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$27.00	$19.00
250mg	95%	in stock	$54.00	$38.00
1g	95%	in stock	$180.00	$126.00

Description

• Catalog Number: AE50568
• Chemical Name: 3,4-Dichloro-1H-pyrrole-2,5-dione
• CAS Number: 1193-54-0
• Molecular Formula: C4HCl2NO2
• Molecular Weight: 165.9622
• MDL Number: MFCD01716135
• SMILES: O=C1NC(=O)C(=C1Cl)Cl

Computed Properties

• Complexity: 199
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 1

Upstream Synthesis Route

The 3,4-Dichloro-1H-pyrrole-2,5-dione is a versatile compound that finds wide application in chemical synthesis processes. This compound is commonly used as a key building block in the synthesis of various pharmaceuticals, agrochemicals, and advanced materials due to its unique reactivity and structural properties.In chemical synthesis, 3,4-Dichloro-1H-pyrrole-2,5-dione serves as a valuable intermediate in the production of heterocyclic compounds with diverse biological activities. Its ability to undergo various functional group transformations allows for the introduction of specific functional groups at the desired positions in the final target molecules. This enables chemists to design and synthesize complex molecules more efficiently and with improved control over stereochemistry.Furthermore, the presence of electron-withdrawing chlorine atoms in 3,4-Dichloro-1H-pyrrole-2,5-dione enhances its reactivity towards nucleophilic substitution reactions, facilitating the formation of new carbon-carbon and carbon-heteroatom bonds. This reactivity profile makes it a versatile tool for the construction of intricate molecular architectures in organic synthesis.Overall, the diverse applications of 3,4-Dichloro-1H-pyrrole-2,5-dione in chemical synthesis highlight its significance as a valuable building block for the development of novel compounds with potential applications in pharmaceuticals, agrochemicals, and materials science.

Literature

• In situ maleimide bridging of disulfides and a new approach to protein PEGylation.

  Bioconjugate chemistry 20110216

• Circular dichroism of some optically active 2,3-dichloromaleimides.

  Enantiomer 20010101