1193383-09-3 | JNJ-42041935

Packsize	Purity	Availability	Price	Discounted Price
1mg	98+%	in stock	$18.00	$13.00
5mg	98+%	in stock	$42.00	$30.00
10mg	98+%	in stock	$61.00	$43.00

Description

• Catalog Number: AA23925
• Chemical Name: JNJ-42041935
• CAS Number: 1193383-09-3
• Molecular Formula: C12H6ClF3N4O3
• Molecular Weight: 346.6492
• MDL Number: MFCD25541711
• SMILES: OC(=O)c1cnn(c1)c1[nH]c2c(n1)cc(c(c2)Cl)OC(F)(F)F

Computed Properties

• Complexity: 469
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 3.1

Literature

• The stabilization of hypoxia inducible factor modulates differentiation status and inhibits the proliferation of mouse embryonic stem cells.

  Chemico-biological interactions 20160125

• Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.

  Molecular pharmacology 20110601