119478-55-6 | Danofloxacin mesylate

Packsize	Purity	Availability	Price	Discounted Price
50mg	98%	in stock	$7.00	$5.00
100mg	98%	in stock	$9.00	$6.00
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$27.00	$19.00
25g	98%	in stock	$78.00	$55.00

Description

• Catalog Number: AA24248
• Chemical Name: Danofloxacin mesylate
• CAS Number: 119478-55-6
• Molecular Formula: C20H24FN3O6S
• Molecular Weight: 453.4845
• MDL Number: MFCD00673687
• SMILES: CS(=O)(=O)O.CN1C[C@@H]2C[C@H]1CN2c1cc2c(cc1F)c(=O)c(cn2C1CC1)C(=O)O

Computed Properties

• Complexity: 772
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 10
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3

Literature

• Photodegradation of fluoroquinolones in surface water and antimicrobial activity of the photoproducts.

  Water research 20121101

• Micelle enhanced and terbium sensitized spectrofluorimetric determination of danofloxacin in milk using molecularly imprinted solid phase extraction.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

• Microwave-assisted extraction and determination of enrofloxacin and danofloxacin photo-transformation products in soil.

  Analytical and bioanalytical chemistry 20120901

• In vivo and ex vivo assessment of the interaction between ivermectin and danofloxacin in sheep.

  Veterinary journal (London, England : 1997) 20120601

• Direct fluorimetric sensing of UV-excited analytes in biological and environmental samples using molecularly imprinted polymer nanoparticles and fluorescence polarization.

  Biosensors & bioelectronics 20120101

• Spectrofluorimetric determination of human serum albumin using terbium-danofloxacin probe.

  TheScientificWorldJournal 20120101

• Pharmacodynamics of antimicrobials against Mycoplasma mycoides mycoides small colony, the causative agent of contagious bovine pleuropneumonia.

  PloS one 20120101

• Involvement of breast cancer resistance protein (BCRP/ABCG2) in the secretion of danofloxacin into milk: interaction with ivermectin.

  Journal of veterinary pharmacology and therapeutics 20110801

• Comparison of different sample treatments for the analysis of quinolones in milk by capillary-liquid chromatography with laser induced fluorescence detection.

  Journal of chromatography. A 20110729

• Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments.

  Veterinary microbiology 20110602

• Short communication: Fluoroquinolone susceptibility of Staphylococcus aureus strains isolated from caprine clinical mastitis in southeast Spain.

  Journal of dairy science 20101101

• Simultaneous determination of quinolones for veterinary use by high-performance liquid chromatography with electrochemical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201

• Preparation and evaluation of danofloxacin mesylate microspheres and its pharmacokinetics in pigs.

  Veterinary research communications 20091201

• Quantification of danofloxacin and difloxacin in chicken tissues in the presence of sarafloxacin as interference.

  Journal of agricultural and food chemistry 20090909

• Quantitation and identity confirmation of residues of quinolones in tilapia fillets by LC-ESI-MS-MS QToF.

  Analytical and bioanalytical chemistry 20090801

• Inert matrix and Na 4 EDTA improve the supercritical fluid extraction efficiency of fluoroquinolones for HPLC determination in pig tissues.

  Talanta 20090430

• Concentrations of danofloxacin 18% solution in plasma, milk and tissues after subcutaneous injection in dairy cows.

  Analytica chimica acta 20090401

• Standard addition analysis of fluoroquinolones in human serum in the presence of the interferent salicylate using lanthanide-sensitized excitation-time decay luminescence data and multivariate curve resolution.

  Talanta 20090315

• Development and validation of a solid-phase extraction method coupled to liquid chromatography with fluorescence detection for the determination of fluoroquinolone residues in powdered infant formulae. Application to the analysis of samples from the Spanish and Latin American market.

  Journal of chromatography. A 20081031

• Effects of fluoroquinolone treatment on MDR1 and MRP2 mRNA expression in Escherichia coli-infected chickens.

  Avian pathology : journal of the W.V.P.A 20081001

• A rapid fluorescence assay for danofloxacin in beef muscle: effect of muscle type on limit of quantitation.

  Journal of food protection 20080801

• Monitoring of fluoroquinolone residual levels in chicken eggs by microbiological assay and confirmation by liquid chromatography.

  Biomedical chromatography : BMC 20080101

• Allometric scaling of marbofloxacin, moxifloxacin, danofloxacin and difloxacin pharmacokinetics: a retrospective analysis.

  Journal of veterinary pharmacology and therapeutics 20071001

• [Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].

  Se pu = Chinese journal of chromatography 20070701

• Simultaneous multiresidue determination of tetracyclines and fluoroquinolones in catfish muscle using high performance liquid chromatography with fluorescence detection.

  Analytica chimica acta 20070314

• Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters.

  British journal of pharmacology 20070201

• Pharmacokinetics of danofloxacin in horses after intravenous, intramuscular and intragastric administration.

  Equine veterinary journal 20060701

• Effect of danofloxacin (Advocin A180) on goats affected with contagious caprine pleuropneumonia.

  Tropical animal health and production 20060101

• [Simultaneous determination of four fluoroquinolone residues in edible chicken tissues by reversed-phase high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20050501

• Comparison of pharmacokinetics of danofloxacin and enrofloxacin in calves challenged with Mannheimia haemolytica.

  American journal of veterinary research 20050201

• Some fundamental and technical aspects of the quantitative analysis of pharmaceutical drugs by matrix-assisted laser desorption/ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Multiresidue determination of fluoroquinolones in shrimp by liquid chromatography-fluorescence-mass spectrometry.

  Journal of AOAC International 20050101

• Multiresidue method for simultaneous determination of ten quinolone antibacterial residues in multimatrix/multispecies animal tissues by liquid chromatography with fluorescence detection: single laboratory validation study.

  Journal of AOAC International 20050101

• Multiresidue determination of eleven quinolones in milk by liquid chromatography with fluorescence detection.

  Journal of AOAC International 20050101

• [Simultaneous determination of quinolones in foods by LC/MS/MS].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041001

• Efficacy of danofloxacin in the treatment of respiratory disease in European cattle.

  The Veterinary record 20040508

• Effect of danofloxacin and tilmicosin on body temperatures of beef calves with pneumonia experimentally induced by inoculation with Mannheimia haemolytica.

  American journal of veterinary research 20040501

• Putative biomarkers for evaluating antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection.

  Research in veterinary science 20030601

• Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs.

  Research in veterinary science 20030601

• The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia.

  Journal of veterinary pharmacology and therapeutics 20030601

• Using nonaqueous capillary electrophoresis to analyze several quinolones in pig kidney samples.

  Electrophoresis 20020201

• Pharmacokinetics and pharmacodynamics of danofloxacin in serum and tissue fluids of goats following intravenous and intramuscular administration.

  American journal of veterinary research 20011201

• Disposition kinetics of danofloxacin and ciprofloxacin in broiler chickens.

  DTW. Deutsche tierarztliche Wochenschrift 20011001

• Some pharmacokinetic data for danofloxacin in healthy goats.

  Veterinary research communications 20010701

• Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolated from pigs in Korea using new standardized procedures.

  The Journal of veterinary medical science 20010301