119577-28-5 | 7-Ethyl-10-hydroxycamptothecin

Packsize	Purity	Availability	Price	Discounted Price
50mg	98%	in stock	$328.00	$229.00
100mg	98%	in stock	$626.00	$438.00
250mg	98%	in stock	$940.00	$658.00
1g	98%	in stock	$2,355.00	$1,648.00

Description

• Catalog Number: AX62641
• Chemical Name: 7-Ethyl-10-hydroxycamptothecin
• CAS Number: 119577-28-5
• Molecular Formula: C22H20N2O5
• Molecular Weight: 392.4046
• MDL Number: MFCD06762720
• SMILES: CCc1ccc(c2c1nc1-c3cc4c(c(=O)n3Cc1c2)COC(=O)[C@]4(O)CC)O

Upstream Synthesis Route

7-Ethyl-10-hydroxycamptothecin, also known as SN-38, is a potent and widely used chemical compound in chemical synthesis. This derivative of camptothecin has proven to be valuable in various synthetic applications due to its unique structural properties and biological activities. In particular, 7-Ethyl-10-hydroxycamptothecin is frequently utilized as a key building block in the synthesis of novel pharmaceutical agents such as anticancer drugs.Its functional groups make it an ideal candidate for modification and derivatization, allowing chemists to tailor its properties for specific applications. The hydroxyl group at position 10, in particular, provides a convenient site for introducing modifications that can enhance the compound's solubility, stability, and bioavailability in target formulations. Additionally, the ethyl group at position 7 can be leveraged for further structural modifications to fine-tune the compound's pharmacological properties.Moreover, the presence of a lactone ring in the camptothecin core structure grants flexibility for chemists to design diverse synthetic routes for accessing 7-Ethyl-10-hydroxycamptothecin derivatives. By manipulating the lactone moiety or other parts of the molecule, researchers can create analogs with improved therapeutic profiles or novel mechanisms of action.Overall, the versatile nature of 7-Ethyl-10-hydroxycamptothecin makes it a valuable tool in chemical synthesis for developing new drug candidates with enhanced efficacy and reduced side effects. Its application in medicinal chemistry holds great promise for advancing the field of pharmaceutical research and improving treatment options for various diseases.