1198097-97-0 | Mirin

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$15.00	$10.00
5mg	98%	in stock	$18.00	$12.00
10mg	98%	in stock	$22.00	$15.00
25mg	98%	in stock	$28.00	$19.00
50mg	98%	in stock	$40.00	$28.00
100mg	98%	in stock	$63.00	$44.00
250mg	98%	in stock	$103.00	$72.00

Description

• Catalog Number: AE11539
• Chemical Name: Mirin
• CAS Number: 1198097-97-0
• Molecular Formula: C10H8N2O2S
• Molecular Weight: 220.2477
• MDL Number: MFCD05885480
• SMILES: O=C1N/C(=N)/SC1=Cc1ccc(cc1)O

Computed Properties

• Complexity: 330
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.5

Literature

• Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1.

  Cancer research 20120601

• ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining.

  Cell cycle (Georgetown, Tex.) 20100715

• FANCD2: A DNA binding protein regulated by MRE11-RAD50-NBS1.

  Cell cycle (Georgetown, Tex.) 20100115

• Discovery of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione, a readily available and orally active glitazone for the treatment of concanavalin A-induced acute liver injury of BALB/c mice.

  Journal of medicinal chemistry 20100114

• Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells.

  Nature structural & molecular biology 20090801

• Corrected structure of mirin, a small-molecule inhibitor of the Mre11-Rad50-Nbs1 complex.

  Nature chemical biology 20090301

• A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex.

  Nature chemical biology 20080201

• Small molecule versus DNA repair nanomachine.

  Nature chemical biology 20080201