1201438-56-3 | Duvelisib

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$20.00	$14.00
25mg	98%	in stock	$232.00	$163.00
50mg	≥98%	in stock	$397.00	$278.00
100mg	95%	in stock	$413.00	$289.00
250mg	95%	in stock	$789.00	$552.00
1g	98%	in stock	$1,909.00	$1,336.00

Description

• Catalog Number: AA34002
• Chemical Name: Duvelisib
• CAS Number: 1201438-56-3
• Molecular Formula: C22H17ClN6O
• Molecular Weight: 416.8630
• MDL Number: MFCD15144635
• SMILES: Clc1cccc2c1c(=O)n(c(c2)[C@@H](Nc1ncnc2c1nc[nH]2)C)c1ccccc1

Computed Properties

• Complexity: 668
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 30
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 4.1

Literature

• Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance.

  Journal of molecular biology 20170217

• PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models.

  Chemistry & biology 20131121