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AE11239

1204313-51-8 | Icotinib (Hydrochloride)

Packsize Purity Availability Price Discounted Price    Quantity
5mg 99% 1 week $150.00 $105.00 -   +
10mg 99% 1 week $193.00 $135.00 -   +
50mg 99% 1 week $465.00 $325.00 -   +

*All products are for research use only and not intended for human or animal use.

*All prices are in USD.

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Description
Catalog Number: AE11239
Chemical Name: Icotinib (Hydrochloride)
CAS Number: 1204313-51-8
Molecular Formula: C22H22ClN3O4
Molecular Weight: 427.8808
MDL Number: MFCD22124500
SMILES: C#Cc1cccc(c1)Nc1ncnc2c1cc1OCCOCCOCCOc1c2.Cl

 

Upstream Synthesis Route 
  • Icotinib hydrochloride, also known as Conmana, is a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with potential antineoplastic activity. It inhibits the quinazoline binding region of the receptor and prevents the receptor's signal transduction pathways from being activated, resulting in the inhibition of cell proliferation and increased cell death in EGFR-overexpressing tumor cells. This pharmaceutical compound is commonly used in chemical synthesis for the development of novel drug candidates targeting EGFR-related diseases, particularly in the treatment of non-small cell lung cancer. Its high potency and specificity make it a valuable tool in medicinal chemistry research aimed at designing more effective and targeted cancer therapies.
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