1207253-08-4 | 5''-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$35.00	$24.00
5mg	97%	in stock	$75.00	$52.00
10mg	97%	in stock	$110.00	$77.00
25mg	97%	in stock	$188.00	$131.00
50mg	97%	in stock	$298.00	$208.00

Description

• Catalog Number: AB52833
• Chemical Name: 5''-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide
• CAS Number: 1207253-08-4
• Molecular Formula: C24H20ClN5O3
• Molecular Weight: 461.9003
• MDL Number: MFCD28502027
• SMILES: COc1nc(CNC(=O)c2cc(cnc2c2ccccn2)c2cncc(c2)Cl)ccc1OC

Computed Properties

• Complexity: 629
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 33
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 7
• XLogP3: 2.7

Upstream Synthesis Route

$name$ is a versatile compound widely used in chemical synthesis, particularly in the field of coordination chemistry. Its unique structure consisting of a 5''-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide moiety allows for precise coordination with various metal ions. This compound serves as a valuable building block for constructing coordination complexes with well-defined structures and properties. Its functional groups enable selective binding with specific metal centers, making it a valuable tool in designing catalysts, sensors, and other functional materials. Additionally, $name$ can be modified to introduce specific functionalities or to fine-tune its coordination properties, expanding its applications in advanced chemical synthesis techniques.

Literature

• Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man.

  Scientific reports 20160101

• Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia.

  Bioorganic & medicinal chemistry letters 20141015

• Discovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia.

  ChemMedChem 20140201