121-34-6 | Vanillic acid

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$6.00	$4.00
25g	98%	in stock	$10.00	$7.00
100g	98%	in stock	$32.00	$22.00

Description

• Catalog Number: AB67626
• Chemical Name: Vanillic acid
• CAS Number: 121-34-6
• Molecular Formula: C8H8O4
• Molecular Weight: 168.1467
• MDL Number: MFCD00002551
• SMILES: COc1cc(ccc1O)C(=O)O

Computed Properties

• Complexity: 168
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1.4

Literature

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• Molecular dynamics simulation study of the vanillate transport channel of Opdk.

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• [Studies on chemical constituents from Serissa serissoides].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070401

• Production of vanillin from waste residue of rice bran oil by Aspergillus niger and Pycnoporus cinnabarinus.

  Bioresource technology 20070301

• 3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

  Bioorganic & medicinal chemistry 20070301

• Genome-wide investigation of aromatic acid transporters in Corynebacterium glutamicum.

  Microbiology (Reading, England) 20070301

• Microbial transformation of ferulic acid to vanillic acid by Streptomyces sannanensis MTCC 6637.

  Journal of industrial microbiology & biotechnology 20070201

• Antitubercular dihydroagarofuranoid sesquiterpenes from the roots of Microtropis fokienensis.

  Journal of natural products 20070201

• Biotransformation of isoeugenol to vanillin by Pseudomonas putida IE27 cells.

  Applied microbiology and biotechnology 20070101

• Protective effect of picroliv against hydrazine-induced hyperlipidemia and hepatic steatosis in rats.

  Drug and chemical toxicology 20070101

• Chemotaxonomic variability in Zizyphus mouritiana varieties and its pharmacological properties in relation to human health.

  Journal of herbal pharmacotherapy 20070101

• Transcriptional regulation of catabolic pathways for aromatic compounds in Corynebacterium glutamicum.

  Genetics and molecular research : GMR 20061207

• Metabolism of isoeugenol via isoeugenol-diol by a newly isolated strain of Bacillus subtilis HS8.

  Applied microbiology and biotechnology 20061201

• [Chemical constitutents of Bauhinia aurea].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201

• [Study on chemical constituents of mangrove Acanthus ilcifolius].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201

• Chemical and biological characterization of dissolved organic matter from silver fir and beech forest soils.

  Chemosphere 20061001

• Anti-inflammatory action of phenolic compounds from Gastrodia elata root.

  Archives of pharmacal research 20061001

• Effect of Picroliv on cadmium-induced hepatic and renal damage in the rat.

  Human & experimental toxicology 20061001

• [Studies on chemical constituents in roots of Rumex dentatus].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001

• Transition metal-catalyzed nonoxidative decarboxylation reactions.

  Biochemistry 20060905

• Bioconversion of ferulic acid to vanillic acid by Halomonas elongata isolated from table-olive fermentation.

  FEMS microbiology letters 20060901

• Studies on chemical constituents from Ilex pubescens.

  Journal of Asian natural products research 20060901

• Molecular cloning of streptomyces genes encoding vanillate demethylase.

  Bioscience, biotechnology, and biochemistry 20060901

• Hydrogen sulfide mediates hypoxia-induced relaxation of trout urinary bladder smooth muscle.

  The Journal of experimental biology 20060801

• Isolation and characterization of Streptomyces sp. NL15-2K capable of degrading lignin-related aromatic compounds.

  Journal of bioscience and bioengineering 20060801

• Plant growth inhibitors isolated from sugarcane (Saccharum officinarum) straw.

  Journal of plant physiology 20060701

• Polypodium leucotomos extract: antioxidant activity and disposition.

  Toxicology in vitro : an international journal published in association with BIBRA 20060601

• [Study on the chemical constituents of Mitragyna rotundifolia].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060601

• [Studies on chemical constituents in rhizome of Elaeagnus bockii I].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060601

• Evaluation of the antioxidant properties and bioavailability of free and bound phenolic acids from Trichilia emetica Vahl.

  Journal of ethnopharmacology 20060524

• Wood stimulates the demethoxylation of [O14CH3]-labeled lignin model compounds by the white-rot fungi Phanerochaete chrysosporium and Phlebia radiata.

  Archives of microbiology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• [Study on chemical constituents of Cyclocarya paliurus].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060501

• Preferential sorption of phenolic phytotoxins to soil: implications for altering the availability of allelochemicals.

  Journal of agricultural and food chemistry 20060419

• Caged vanilloid ligands for activation of TRPV1 receptors by 1- and 2-photon excitation.

  Biochemistry 20060418

• Study on the nitric oxide scavenging effects of ginseng and its compounds.

  Journal of agricultural and food chemistry 20060405

• Vanillic acid glycoside and quinic acid derivatives from Gardeniae Fructus.

  Journal of natural products 20060401

• Phenolic components and antioxidant activity of Fernblock, an aqueous extract of the aerial parts of the fern Polypodium leucotomos.

  Methods and findings in experimental and clinical pharmacology 20060401

• [Study on the chemical constituents of Ardisia chinensis].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060401

• Complex formation of neptunium(V) with 4-hydroxy-3-methoxybenzoic acid studied by time-resolved laser-induced fluorescence spectroscopy with ultra-short laser pulses.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060301

• Comparison of natural organic acids and synthetic chelates at enhancing phytoextraction of metals from a multi-metal contaminated soil.

  Environmental pollution (Barking, Essex : 1987) 20060301

• Joint action of benzoxazinone derivatives and phenolic acids.

  Journal of agricultural and food chemistry 20060222

• Determination of active ingredients of Ilex Purpurea Hassk and its medicinal preparations by capillary electrophoresis with electrochemical detection.

  Journal of pharmaceutical and biomedical analysis 20060213

• [Studies on chemical constituents in stem of Dendrobium chrysotoxum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201

• Antibacterial activity directed isolation of compounds from Onosma hispidum.

  Microbiological research 20060101

• Structural analysis of ligand binding and catalysis in chorismate lyase.

  Archives of biochemistry and biophysics 20060101

• Adsorption of bile acid by chitosan salts prepared with cinnamic acid and analogue compounds.

  Journal of biomaterials science. Polymer edition 20060101

• Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone.

  BMC complementary and alternative medicine 20060101

• Phenols and lignans from Chenopodium album.

  Phytochemical analysis : PCA 20060101

• Functional coupling between vanillate-O-demethylase and formaldehyde detoxification pathway.

  FEMS microbiology letters 20051215

• [Chemical constituents from leaves of Phyllostachys pubescens I].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

• Protective effect of capsinoid on lipid peroxidation in rat tissues induced by Fe-NTA.

  Free radical research 20051101

• Molecular characterization of the gallate dioxygenase from Pseudomonas putida KT2440. The prototype of a new subgroup of extradiol dioxygenases.

  The Journal of biological chemistry 20051021

• Characterization of the oxidase activity in mammalian catalase.

  The Journal of biological chemistry 20051021

• Isolation of three new naturally occurring compounds from the culture of Micromonospora sp. P1068.

  Natural product research 20051001

• Structure influence on biophenols solubility in model biomembranes detected by differential scanning calorimetry.

  Molecular nutrition & food research 20051001

• Prevention of acute cadmium toxicity by Picroliv.

  Human & experimental toxicology 20051001

• Transportation mechanism for vanillin uptake through fungal plasma membrane.

  Applied microbiology and biotechnology 20050901

• Clostridium carboxidivorans sp. nov., a solvent-producing clostridium isolated from an agricultural settling lagoon, and reclassification of the acetogen Clostridium scatologenes strain SL1 as Clostridium drakei sp. nov.

  International journal of systematic and evolutionary microbiology 20050901

• [Studies on chemical constituents from flowers of Apocynum venetum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050901

• Vanillate metabolism in Corynebacterium glutamicum.

  Current microbiology 20050701

• Effect of pH on the inhibition of Listeria spp. by vanillin and vanillic acid.

  Journal of food protection 20050701

• [Phenolics from traditional Chinese medicine Sargentodoxa cuneata].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050701

• Toward a better understanding on the mechanism of ortholithiation. Tuning of selectivities in the metalation of meta-anisic acid by an appropriate choice of base.

  Organic letters 20050609

• Key enzymes of the protocatechuate branch of the beta-ketoadipate pathway for aromatic degradation in Corynebacterium glutamicum.

  Science in China. Series C, Life sciences 20050601

• Protective activity of picroliv on hepatic amoebiasis associated with carbon tetrachloride toxicity.

  The Indian journal of medical research 20050501

• [Interactive effects between allelochemical substitutes].

  Ying yong sheng tai xue bao = The journal of applied ecology 20050501

• Efficacy of picroliv in combination with miltefosine, an orally effective antileishmanial drug against experimental visceral leishmaniasis.

  Acta tropica 20050401

• Metabolism of isovanillin by aldehyde oxidase, xanthine oxidase, aldehyde dehydrogenase and liver slices.

  Pharmacology 20050301

• A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase.

  Nitric oxide : biology and chemistry 20050301

• [Studies on the chemical constituents from Fructus Rubi].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050201

• Effect of picroliv administration on hepatic microsomal mixed function oxidases and glutathione-conjugating enzyme system in cholestatic rats.

  Hindustan antibiotics bulletin 20050201

• Heterologous expression of the plant coumarate: CoA ligase in Lactococcus lactis.

  Letters in applied microbiology 20050101

• [Studies on the active constituents in vine stem of Spatholobus suberectus].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101

• Activity of single components of Ferula hermonis on male rat sexual behavior.

  International journal of impotence research 20050101

• Chemical investigation and authenticity of Indian vanilla beans.

  Journal of agricultural and food chemistry 20041215

• Bufadienolides from Drimia robusta and Urginea epigea (Hyacinthaceae).

  Phytochemistry 20041201

• Antimicrobial screening and quantitative determination of benzoic acid derivative of Gomphrena celosioides by TLC-densitometry.

  Chemical & pharmaceutical bulletin 20041101

• Characterization of natural organic matters effect on the biodegradation in the slow sand filter.

  Journal of environmental biology 20041001

• Pattern profiling of the herbal preparation picroliv using liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20040806

• Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation.

  The Journal of biological chemistry 20040702

• Ex planta phytoremediation of trichlorophenol and phenolic allelochemicals via an engineered secretory laccase.

  Nature biotechnology 20040701

• [Study on the interactions between four components in Ligusticum chuanxiong rhizome and acceptors on cardiac muscle membrane].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040701

• Biomass burning as the main source of organic aerosol particulate matter in Malaysia during haze episodes.

  Chemosphere 20040501

• [Study on the chemical constituent from Buddleja purdomii].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040501

• [Studies on chemical constituents of sini tang].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501

• Acylated flavone C-glycosides from Trollius ledebouri.

  Journal of natural products 20040401

• LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam.

  Phytochemistry 20040401

• Effect of low and very low doses of simple phenolics on plant peroxidase activity.

  Nonlinearity in biology, toxicology, medicine 20040401

• Phenyl methyl ethers: novel electron donors for respiratory growth of Desulfitobacterium hafniense and Desulfitobacterium sp. strain PCE-S.

  Archives of microbiology 20040301

• Signal quenching, detoxification and mineralization of vir gene-inducing phenolics by the VirH2 protein of Agrobacterium tumefaciens.

  Molecular microbiology 20040201

• Identification of the major vanilloid component in Capsicum extract by HPLC-EC and HPLC-MS.

  Phytochemical analysis : PCA 20040101

• [Phenyl pyrazolones--novel oxidoreductase redox-mediators for degradation of xenobiotics].

  Prikladnaia biokhimiia i mikrobiologiia 20040101

• [Isolation and structural identification of chemical constituents from Selaginella tamariscina (Beauv.) Spring].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040101

• Antioxidant activity of phenolic and related compounds: a density functional theory study on the O-H bond dissociation enthalpy.

  Redox report : communications in free radical research 20040101

• Tyrosinase inhibitor from black rice bran.

  Journal of agricultural and food chemistry 20031119

• Mechanistic features of lignin peroxidase-catalyzed oxidation of substituted phenols and 1,2-dimethoxyarenes.

  The Journal of biological chemistry 20031010

• Biotransformations of propenylbenzenes by an Arthrobacter sp. and its t-anethole blocked mutants.

  Journal of biotechnology 20031009

• [The isolation and identification of a new alpha-pyrone from Opuntia dillenii].

  Yao xue xue bao = Acta pharmaceutica Sinica 20030701

• Lignin degradation in a compost environment by the deuteromycete Paecilomyces inflatus.

  Applied microbiology and biotechnology 20030501

• Absolute stereostructures of new arborinane-type triterpenoids and inhibitors of nitric oxide production from Rubia yunnanensis.

  Journal of natural products 20030501

• 4-Hydroxy-3-methoxybenzoic acid methyl ester: a curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: potential for prostate cancer management.

  Neoplasia (New York, N.Y.) 20030501

• Detoxification of ferulic acid by ectomycorrhizal fungi.

  Mycorrhiza 20030401

• [Two new phenylethanoid glycosides from Corallodiscus flabellata].

  Yao xue xue bao = Acta pharmaceutica Sinica 20030401

• Degradation of vanillic acid and production of guaiacol by microorganisms isolated from cork samples.

  FEMS microbiology letters 20030314

• Modulation of carcinogenic response and antioxidant enzymes of rats administered with 1,2-dimethylhydrazine by Picroliv.

  Cancer letters 20030310

• Picroliv modulates antioxidant status and down-regulates AP1 transcription factor after hemorrhage and resuscitation.

  Shock (Augusta, Ga.) 20030201

• Inhibitory effects of urinary metabolites on platelet aggregation after orally administering Shimotsu-To, a traditional Chinese medicine, to rats.

  The Journal of pharmacy and pharmacology 20030201

• Induction of laccase activity in the edible straw mushroom, Volvariella volvacea.

  FEMS microbiology letters 20030121

• Alicycliphilus denitrificans gen. nov., sp. nov., a cyclohexanol-degrading, nitrate-reducing beta-proteobacterium.

  International journal of systematic and evolutionary microbiology 20030101

• Effect of phenolic monomers on biomass and hydrolytic enzyme activities of an anaerobic fungus isolated from wild nil gai (Baselophus tragocamelus).

  Letters in applied microbiology 20030101

• Relationship of demethylation processes to veratric acid concentration and cell density in cultures of Rhodococcus erythropolis.

  Cell biology international 20030101

• [Studies on the chemical constituents from herba of Corallodiscus flabellata].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20021201

• Amperometric biosensors for detection of phenol using chemically modified electrodes containing immobilized bacteria.

  Biosensors & bioelectronics 20021001

• [A study on chemical constituents in the herb of Mentha spicata].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20021001

• Characterization of the 5-carboxyvanillate decarboxylase gene and its role in lignin-related biphenyl catabolism in Sphingomonas paucimobilis SYK-6.

  Applied and environmental microbiology 20020901

• N-Acylvanillamides: development of an expeditious synthesis and discovery of new acyl templates for powerful activation of the vanilloid receptor.

  Journal of medicinal chemistry 20020815

• Biochemical basis for wheat seedling allelopathy on the suppression of annual ryegrass (Lolium rigidum).

  Journal of agricultural and food chemistry 20020731

• Antiviral activity of Plantago major extracts and related compounds in vitro.

  Antiviral research 20020701

• Determination of free and total phenolic acids in plant-derived foods by HPLC with diode-array detection.

  Journal of agricultural and food chemistry 20020619

• Antioxidant activity of prune (Prunus domestica L.) constituents and a new synergist.

  Journal of agricultural and food chemistry 20020619

• Vanillylamide-based propanolamine derivative displays alpha/beta-adrenoceptor blocking and vasodilating properties.

  Journal of cardiovascular pharmacology 20020601

• Antioxidant activity of phenolic compounds isolated from Mesona procumbens Hemsl.

  Journal of agricultural and food chemistry 20020508

• Isolation from a shea cake digester of a tannin-tolerant Escherichia coli strain decarboxylating p-hydroxybenzoic and vanillic acids.

  Current microbiology 20020501

• 4-Hydroxycinnamoyl-CoA hydratase/lyase, an enzyme of phenylpropanoid cleavage from Pseudomonas, causes formation of C(6)-C(1) acid and alcohol glucose conjugates when expressed in hairy roots of Datura stramonium L.

  Planta 20020501

• Blennione, a green aminobenzoquinone derivative from Lactarius blennius.

  Journal of natural products 20020501

• The trans-anethole degradation pathway in an Arthrobacter sp.

  The Journal of biological chemistry 20020405

• Influence of aromatic compounds on biodegradation of [14C]-labeled xylan and mannan by the white-rot fungus Phlebia radiata.

  Journal of industrial microbiology & biotechnology 20020301

• Growth hormone inhibits apoptosis in in vitro produced bovine embryos.

  Molecular reproduction and development 20020201

• Peroxidase and phenylalanine ammonia-lyase activities, phenolic acid contents, and allelochemicals-inhibited root growth of soybean.

  Biological research 20020101

• A biotechnological process involving filamentous fungi to produce natural crystalline vanillin from maize bran.

  Applied biochemistry and biotechnology 20020101

• [Studies on chemical constituent of Solanum lyratum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020101

• Comamonas testosteroni BR6020 possesses a single genetic locus for extradiol cleavage of protocatechuate.

  Microbiology (Reading, England) 20010801

• Caffeic acid derivatives in artichoke extract are metabolised to phenolic acids in vivo.

  Free radical research 20010801

• Rerouting the plant phenylpropanoid pathway by expression of a novel bacterial enoyl-CoA hydratase/lyase enzyme function.

  The Plant cell 20010701

• Studies on germination conditions and antioxidant contents of wheat grain.

  International journal of food sciences and nutrition 20010701

• Characterization of a three-component vanillate O-demethylase from Moorella thermoacetica.

  Journal of bacteriology 20010601

• Novel biomarkers of the metabolism of caffeic acid derivatives in vivo.

  Free radical biology & medicine 20010601

• Long term effect of aflatoxin B(1) on lipid peroxidation in rat liver and kidney: effect of picroliv and silymarin.

  Phytotherapy research : PTR 20010601

• Enhancement of sweetness ratings of aspartame by a vanilla odor presented either by orthonasal or retronasal routes.

  Perceptual and motor skills 20010601

• Isolation and characterization of a veratrol:corrinoid protein methyl transferase from Acetobacterium dehalogenans.

  Archives of microbiology 20010501

• Clostridium uliginosum sp. nov., a novel acid-tolerant, anaerobic bacterium with connecting filaments.

  International journal of systematic and evolutionary microbiology 20010501

• Vanilloid and isovanilloid analogues as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases.

  Bioorganic & medicinal chemistry letters 20010423

• [The structures and characteristic infrared spectra of beta-DDB and its derivatives].

  Guang pu xue yu guang pu fen xi = Guang pu 20010401

• Biochemical changes induced in liver and serum of aflatoxin B1-treated male wistar rats: preventive effect of picroliv.

  Pharmacology & toxicology 20010201

• Kinetics of finite dose absorption through skin 1. Vanillylnonanamide.

  Journal of pharmaceutical sciences 20010201

• Quantitative and qualitative precision improvements by effective mobility-scale data transformation in capillary electrophoresis analysis.

  Electrophoresis 20010101

• Protective effect of Picroliv, the active constituent of Picrorhiza kurroa, against chemical carcinogenesis in mice.

  Teratogenesis, carcinogenesis, and mutagenesis 20010101

• Vanillic acid 4-O-beta-D-(6'-O-galloyl) glucopyranoside and other constituents from the bark of Terminalia macroptera Guill.et Perr.

  Natural product letters 20010101

• [Studies on chemical constituents from Buddleja lindleyana Fert].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010101

• The 4-oxalomesaconate hydratase gene, involved in the protocatechuate 4,5-cleavage pathway, is essential to vanillate and syringate degradation in Sphingomonas paucimobilis SYK-6.

  Journal of bacteriology 20001201

• Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345.

  Agents and actions 19901101

• Cloning and sequencing of Pseudomonas genes encoding vanillate demethylase.

  Journal of bacteriology 19881001

• Enzymatic release of halogens or methanol from some substituted protocatechuic acids.

  Journal of bacteriology 19850501

• Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus.

  Applied and environmental microbiology 19830501