1217501-22-8 | 3-(N-t-butyl-N-methylsulfamoyl)phenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$203.00	$142.00
1g	98%	in stock	$573.00	$402.00

Description

• Catalog Number: AA53962
• Chemical Name: 3-(N-t-butyl-N-methylsulfamoyl)phenylboronic acid
• CAS Number: 1217501-22-8
• Molecular Formula: C11H18BNO4S
• Molecular Weight: 271.1409
• MDL Number: MFCD12756419
• SMILES: OB(c1cccc(c1)S(=O)(=O)N(C(C)(C)C)C)O

Computed Properties

• Complexity: 372
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4

Upstream Synthesis Route

(3-(N-(tert-Butyl)-N-methylsulfamoyl)phenyl)boronic acid is a versatile reagent commonly employed in chemical synthesis. This compound serves as a valuable building block in the preparation of various biologically active molecules, pharmaceutical intermediates, and functional materials.Its unique structure, containing both the boronic acid motif and the sulfonamide functionality, makes it particularly useful in cross-coupling reactions, such as Suzuki-Miyaura coupling. By forming stable boronate esters with aryl halides or triflates, it facilitates the introduction of the phenylsulfamoyl group onto a wide range of organic substrates.Furthermore, the tert-butyl and methyl substituents on the sulfonamide nitrogen enhance the reactivity and stability of the compound, allowing for efficient transformations under mild reaction conditions. Overall, the application of (3-(N-(tert-Butyl)-N-methylsulfamoyl)phenyl)boronic acid in chemical synthesis offers chemists a powerful tool for the strategic diversification of molecular structures.