1217501-35-3 | 2-Formyl-4-(trifluoromethyl)phenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$65.00	$45.00
250mg	98%	in stock	$73.00	$51.00
1g	98%	in stock	$126.00	$88.00
5g	98%	in stock	$440.00	$308.00
10g	98%	in stock	$758.00	$531.00
25g	98%	in stock	$1,504.00	$1,053.00

Description

• Catalog Number: AA53949
• Chemical Name: 2-Formyl-4-(trifluoromethyl)phenylboronic acid
• CAS Number: 1217501-35-3
• Molecular Formula: C8H6BF3O3
• Molecular Weight: 217.9376
• MDL Number: MFCD13195656
• SMILES: O=Cc1cc(ccc1B(O)O)C(F)(F)F

Computed Properties

• Complexity: 232
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

The (2-Formyl-4-(trifluoromethyl)phenyl)boronic acid is a versatile compound commonly used in chemical synthesis as a key building block. Its unique structure, featuring a boronic acid functional group and a trifluoromethylphenyl moiety, provides a wide range of applications in the synthesis of pharmaceuticals, agrochemicals, and materials.In organic synthesis, this compound is often employed as a reagent in Suzuki coupling reactions, where it serves as a coupling partner with aryl halides or pseudohalides to form biaryl compounds. This reaction is popular in the pharmaceutical industry for creating complex molecular structures efficiently.Furthermore, the boronic acid moiety in (2-Formyl-4-(trifluoromethyl)phenyl)boronic acid can undergo diverse transformations, such as Suzuki-Miyaura cross-coupling, Chan-Lam coupling, and Sonogashira reactions. These reactions enable the introduction of the trifluoromethylphenyl group into various organic molecules, enhancing their biological activity or physical properties.Overall, the (2-Formyl-4-(trifluoromethyl)phenyl)boronic acid plays a crucial role in modern organic synthesis as a valuable tool for constructing complex molecules with trifluoromethylphenyl functionalities, offering exciting opportunities for drug discovery and material science research.