1218790-79-4 | 2-(2,2,2-Trifluoroethoxy)pyridine-3-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$63.00	$44.00
250mg	97%	in stock	$99.00	$69.00
1g	97%	in stock	$249.00	$175.00
5g	97%	in stock	$945.00	$661.00

Description

• Catalog Number: AA54606
• Chemical Name: 2-(2,2,2-Trifluoroethoxy)pyridine-3-boronic acid
• CAS Number: 1218790-79-4
• Molecular Formula: C7H7BF3NO3
• Molecular Weight: 220.9416
• MDL Number: MFCD07374887
• SMILES: OB(c1cccnc1OCC(F)(F)F)O

Computed Properties

• Complexity: 202
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3

Upstream Synthesis Route

(2-(2,2,2-Trifluoroethoxy)pyridin-3-yl)boronic acid is a versatile and valuable reagent in chemical synthesis due to its unique properties and functionality. This compound is commonly used in Suzuki-Miyaura cross-coupling reactions, a widely employed method for forming carbon-carbon bonds. By acting as a boronic acid, it facilitates the coupling of organic substrates under mild conditions, leading to the efficient synthesis of various biaryl compounds. Additionally, the trifluoroethoxy group enhances the solubility and stability of this boronic acid derivative, making it a practical choice for challenging reactions. Researchers and chemists often utilize this compound in the development of pharmaceuticals, agrochemicals, and materials with specific functionalities, highlighting its importance in modern synthetic chemistry.