1218791-09-3 | 4-Fluoro-3-nitrophenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$32.00	$22.00
1g	98%	in stock	$35.00	$25.00
5g	98%	in stock	$116.00	$82.00

Description

• Catalog Number: AA54627
• Chemical Name: 4-Fluoro-3-nitrophenylboronic acid, pinacol ester
• CAS Number: 1218791-09-3
• Molecular Formula: C12H15BFNO4
• Molecular Weight: 267.0612
• MDL Number: MFCD12546515
• SMILES: [O-][N+](=O)c1cc(ccc1F)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 355
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1

Upstream Synthesis Route

The 2-(4-Fluoro-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a valuable reagent widely used in chemical synthesis as a boronic ester intermediate. This compound serves as a key building block in the creation of various functionalized molecules through Suzuki-Miyaura cross-coupling reactions. By undergoing a palladium-catalyzed coupling with aryl halides or pseudohalides, this boronic ester enables the formation of carbon-carbon bonds with high efficiency and selectivity. As a result, this versatile compound plays a crucial role in the development of pharmaceuticals, agrochemicals, materials science, and other areas of organic synthesis.