122-11-2 | 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide

Packsize	Purity	Availability	Price	Discounted Price
1mg	98+%	in stock	$6.00	$4.00
25mg	98+%	in stock	$8.00	$6.00
1g	98%	in stock	$26.00	$18.00
5g	98%	in stock	$34.00	$24.00
25g	98%	in stock	$74.00	$52.00
50g	≥98%	in stock	$141.00	$99.00
100g	98%	in stock	$203.00	$142.00
500g	98%	in stock	$667.00	$467.00

Description

• Catalog Number: AI14426
• Chemical Name: 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide
• CAS Number: 122-11-2
• Molecular Formula: C12H14N4O4S
• Molecular Weight: 310.3290
• MDL Number: MFCD00057345
• SMILES: COc1nc(OC)nc(c1)NS(=O)(=O)c1ccc(cc1)N

Computed Properties

• Complexity: 420
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 1.6

Literature

• Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats.

  Toxicology letters 20130607

• Thermodynamic analysis of the thermal stability of sulphonamides in milk using liquid chromatography tandem mass spectrometry detection.

  Food chemistry 20130115

• pH-induced phase transition control of thermoresponsive nano-micelles possessing outermost surface sulfonamide moieties.

  Colloids and surfaces. B, Biointerfaces 20121101

• Establishment of evaluation method to determine effects of veterinary medicinal products on manure fermentation using small-scale composting apparatus.

  Journal of bioscience and bioengineering 20120901

• Removal of sulfonamide antibiotics upon conventional activated sludge and advanced membrane bioreactor treatment.

  Analytical and bioanalytical chemistry 20120901

• Optimization of an antibiotic sensitivity assay for Mycoplasma hyosynoviae and susceptibility profiles of field isolates from 1997 to 2011.

  Veterinary microbiology 20120706

• Tissue/fluid correlation study for the depletion of sulfadimethoxine in bovine kidney, liver, plasma, urine, and oral fluid.

  Journal of veterinary pharmacology and therapeutics 20120601

• The implication of mediators for enhancement of laccase oxidation of sulfonamide antibiotics.

  Bioresource technology 20120601

• Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups.

  Pediatric research 20120601

• Prostaglandin synthases influence thyroid follicular cell proliferation but not carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.

  Toxicological sciences : an official journal of the Society of Toxicology 20120601

• Molecular determinants of ligand selectivity for the human multidrug and toxin extruder proteins MATE1 and MATE2-K.

  The Journal of pharmacology and experimental therapeutics 20120601

• Lac color inhibits development of rat thyroid carcinomas through targeting activation of plasma hyaluronan-binding protein.

  Experimental biology and medicine (Maywood, N.J.) 20120601

• Development and validation of an LC-UV method for the determination of sulfonamides in animal feeds.

  Drug testing and analysis 20120501

• Antimicrobial susceptibility patterns and sensitivity to tulathromycin in goat respiratory bacterial isolates.

  Veterinary microbiology 20120423

• Minimum inhibitory concentrations of Staphylococcus aureus recovered from clinical and subclinical cases of bovine mastitis.

  Journal of dairy science 20120401

• Herd-level association between antimicrobial use and antimicrobial resistance in bovine mastitis Staphylococcus aureus isolates on Canadian dairy farms.

  Journal of dairy science 20120401

• Accumulation and effects of sulfadimethoxine in Salix fragilis L. plants: a preliminary study to phytoremediation purposes.

  International journal of phytoremediation 20120401

• Fate of sulfonamide antibiotics in contact with activated sludge--sorption and biodegradation.

  Water research 20120315

• A coordination polymer nanobelt (CPNB)-based aptasensor for sulfadimethoxine.

  Biosensors & bioelectronics 20120315

• Sulfadimethoxine and sulfaguanidine: their sorption potential on natural soils.

  Chemosphere 20120301

• Identification of isobaric amino-sulfonamides without prior separation.

  Rapid communications in mass spectrometry : RCM 20120227

• Removal of sulfa drugs by sewage treatment in aqueous solution systems: activated carbon treatment and ozone oxidation.

  Journal of oleo science 20120101

• Validation of a commercial receptor kit Sulfasensor Honey for the screening of sulfonamides in honey according to Commission Decision 2002/657/EC.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

• Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy.

  Frontiers in pharmacology 20120101

• The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.

  Frontiers in pharmacology 20120101

• Phenotypic and transcriptomic response of auxotrophic Mycobacterium avium subsp. paratuberculosis leuD mutant under environmental stress.

  PloS one 20120101

• Promoting effects of carminic acid-enriched cochineal extracts on capsular invasive thyroid carcinomas through targeting activation of angiogenesis in rats.

  The Journal of toxicological sciences 20120101

• Reconnaissance of selected PPCP compounds in Costa Rican surface waters.

  Water research 20111215

• Outbreaks of severe enteric disease associated with Eimeria furonis infection in ferrets (Mustela putorius furo) of 3 densely populated groups.

  Journal of the American Veterinary Medical Association 20111215

• Two fluoroalcohols as components of basic buffers for liquid chromatography electrospray ionization mass spectrometric determination of antibiotic residues.

  The Analyst 20111107

• Occurrence and removal of pharmaceuticals and personal care products (PPCPs) in an advanced wastewater reclamation plant.

  Water research 20111015

• Ionic liquid-based homogeneous liquid-liquid microextraction for the determination of antibiotics in milk by high-performance liquid chromatography.

  Journal of chromatography. A 20111014

• Temporal variation of pharmaceuticals in an urban and agriculturally influenced stream.

  The Science of the total environment 20111001

• Multiclass detection and quantitation of antibiotics and veterinary drugs in shrimps by fast liquid chromatography time-of-flight mass spectrometry.

  Talanta 20110915

• Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110901

• Antimicrobial susceptibility of Arcanobacterium pyogenes isolated from the lungs of white-tailed deer (Odocoileus virginianus) with pneumonia.

  Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110901

• Biodegradation and bio-sorption of antibiotics and non-steroidal anti-inflammatory drugs using immobilized cell process.

  Chemosphere 20110801

• Field evaluations of the efficacy and safety of Emodepside plus toltrazuril (Procox® oral suspension for dogs) against naturally acquired nematode and Isospora spp. infections in dogs.

  Parasitology research 20110801

• Application of sulphanilamides disazo dyes with Tropaeolin O for simple, rapid and sensitive spectrophotometric assay of medicines.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110701

• Hepatic safety of antibiotics used in primary care.

  The Journal of antimicrobial chemotherapy 20110701

• Development and validation of an HPLC method for the determination of ten sulfonamide residues in milk according to 2002/657/EC.

  Journal of separation science 20110701

• Etiologic and epidemiologic analysis of bacterial infectious upper respiratory disease in Thoroughbred horses at the Seoul Race Park.

  Journal of veterinary science 20110601

• Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms.

  Veterinary microbiology 20110512

• Clinical and microbial efficacy of antimicrobial treatments of experimental avian colibacillosis.

  Veterinary microbiology 20110505

• pH-sensitive PEG-based micelles for tumor targeting.

  Journal of drug targeting 20110501

• Preventive effects of calcitriol on the development of capsular invasive carcinomas in a rat two-stage thyroid carcinogenesis model.

  The Journal of veterinary medical science 20110501

• A novel chemiluminescence quenching method for determination of sulfonamides in pharmaceutical and biological fluid based on luminol-Ag(III) complex reaction in alkaline solution.

  Drug testing and analysis 20110501

• Group-selective molecularly imprinted polymer solid-phase extraction for the simultaneous determination of six sulfonamides in aquaculture products.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110501

• Sorption and biodegradation of sulfonamide antibiotics by activated sludge: experimental assessment using batch data obtained under aerobic conditions.

  Water research 20110501

• Minimum inhibitory concentrations of selected antimicrobial agents for Moraxella bovoculi associated with infectious bovine keratoconjunctivitis.

  Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110501

• Occurrence of steroid hormones and antibiotics in shallow groundwater impacted by livestock waste control facilities.

  Journal of contaminant hydrology 20110425

• Involvement of PTEN/Akt signaling in capsular invasive carcinomas developed in a rat two-stage thyroid carcinogenesis model after promotion with sulfadimethoxine.

  Journal of cancer research and clinical oncology 20110401

• Stress degradation study on sulfadimethoxine and development of a validated stability-indicating HPLC assay.

  Annales pharmaceutiques francaises 20110301

• The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites.

  Avian diseases 20110301

• Occurrence of sulfonamide residues along the Ebro River basin: removal in wastewater treatment plants and environmental impact assessment.

  Environment international 20110201

• Profile of minocycline neuroprotection in bilirubin-induced auditory system dysfunction.

  Brain research 20110112

• Application of fully automated online solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry for the determination of sulfonamides and their acetylated metabolites in groundwater.

  Analytical and bioanalytical chemistry 20110101

• Drug pH-sensitive release in vitro and targeting ability of polyamidoamine dendrimer complexes for tumor cells.

  Chemical & pharmaceutical bulletin 20110101

• PPARδ activation acts cooperatively with 3-phosphoinositide-dependent protein kinase-1 to enhance mammary tumorigenesis.

  PloS one 20110101

• Evolution of a major drug metabolizing enzyme defect in the domestic cat and other felidae: phylogenetic timing and the role of hypercarnivory.

  PloS one 20110101

• Development of a quantitative multiclass/multiresidue method for 21 veterinary drugs in shrimp.

  Journal of AOAC International 20110101

• Thyroid-specific transcription factors and their roles in thyroid cancer.

  Journal of thyroid research 20110101

• Schistosoma-associated Salmonella resist antibiotics via specific fimbrial attachments to the flatworm.

  Parasites & vectors 20110101

• Effects of pH and manure on transport of sulfonamide antibiotics in soil.

  Journal of environmental quality 20110101

• Multi-neuronal recordings in the Basal Ganglia in normal and dystonic rats.

  Frontiers in systems neuroscience 20110101

• Metabolites from fungal laccase-catalysed transformation of sulfonamides.

  Chemosphere 20101201

• Acute hyperbilirubinaemia induces presynaptic neurodegeneration at a central glutamatergic synapse.

  The Journal of physiology 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Multiresidue analysis of sulfonamides in meat by supramolecular solvent microextraction, liquid chromatography and fluorescence detection and method validation according to the 2002/657/EC decision.

  Journal of chromatography. A 20101001

• Use and environmental occurrence of antibiotics in freestall dairy farms with manured forage fields.

  Environmental science & technology 20100901

• Comparison of toltrazuril and sulphadimethoxine in the treatment of intestinal coccidiosis in pet rabbits.

  The Veterinary record 20100821

• Comparison of Salmonella serovar isolation and antimicrobial resistance patterns from porcine samples between 2003 and 2008.

  Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20100701

• Studies on the extraction of sulfonamides from agricultural soils.

  Analytical and bioanalytical chemistry 20100501

• Determination of sulfonamides in soil samples based on alumina-coated magnetite nanoparticles as adsorbents.

  Analytica chimica acta 20100430

• Validation of a liquid chromatography method for the simultaneous determination of sulfadimethoxine and trimethoprim and application to a stability study.

  Annales pharmaceutiques francaises 20100301

• Development of an ultra-high-pressure liquid chromatography-tandem mass spectrometry multi-residue sulfonamide method and its application to water, manure slurry, and soils from swine rearing facilities.

  Journal of chromatography. A 20100219

• Fine needle aspiration cytology in the diagnosis of cervical tuberculosis and paracoccidioidomycosis.

  Cytopathology : official journal of the British Society for Clinical Cytology 20100201

• Lack of modifying effects of prepubertal exposure to acrylamide (AA) on N-methyl-N-nitrosourea (MNU)-induced multi-organ carcinogenesis in F344 rats.

  The Journal of toxicological sciences 20100201

• Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study.

  PloS one 20100101

• Phytotoxic antibiotic sulfadimethoxine elicits a complex hormetic response in the weed lythrum salicaria L.

  Dose-response : a publication of International Hormesis Society 20100101

• Photochemical fate of sulfadimethoxine in aquaculture waters.

  Environmental science & technology 20091115

• A confirmatory method for the simultaneous extraction, separation, identification and quantification of Tetracycline, Sulphonamide, Trimethoprim and Dapsone residues in muscle by ultra-high-performance liquid chromatography-tandem mass spectrometry according to Commission Decision 2002/657/EC.

  Journal of chromatography. A 20091113

• Use of capillary electrophoresis with laser-induced fluorescence detection to screen and liquid chromatography-tandem mass spectrometry to confirm sulfonamide residues: validation according to European Union 2002/657/EC.

  Journal of chromatography. A 20091113

• Fast and selective extraction of sulfonamides from honey based on magnetic molecularly imprinted polymer.

  Journal of agricultural and food chemistry 20091111

• Analysis of sulfonamides in environmental water samples based on magnetic mixed hemimicelles solid-phase extraction coupled with HPLC-UV detection.

  Chemosphere 20091101

• A new and simple method to determine trace levels of sulfonamides in honey by high performance liquid chromatography with fluorescence detection.

  Journal of chromatography. A 20091023

• Microbial screening methods for detection of antibiotic residues in slaughter animals.

  Analytical and bioanalytical chemistry 20091001

• Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation.

  Cancer science 20091001

• Rapid separation and highly sensitive detection methodology for sulfonamides in shrimp using a monolithic column coupled with BDD amperometric detection.

  Talanta 20090915

• [Combined effect of antibiotics on anaerobic digestion of piggery wastewater].

  Huan jing ke xue= Huanjing kexue 20090915

• Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice.

  Carcinogenesis 20090901

• Removal of antibiotics and non-steroidal anti-inflammatory drugs by extended sludge age biological process.

  Chemosphere 20090901

• Short communication: Detection limits of non-beta-lactam antibiotics in goat's milk by microbiological residues screening tests.

  Journal of dairy science 20090901

• Atoxoplasmosis in canary fledglings: severe lymphocytic enteritis with preferential parasitism of B lymphocytes.

  Avian diseases 20090901

• Hollow fiber supported ionic liquid membrane microextraction for determination of sulfonamides in environmental water samples by high-performance liquid chromatography.

  Journal of chromatography. A 20090828

• Simultaneous determination of fluoroquinolones, sulfonamides and tetracyclines in sewage sludge by pressurized liquid extraction and liquid chromatography electrospray ionization-mass spectrometry.

  Journal of chromatography. A 20090807

• Solid phase extraction coupled to liquid chromatography-tandem mass spectrometry analysis of sulfonamides, tetracyclines, analgesics and hormones in surface water and wastewater in Luxembourg.

  The Science of the total environment 20090801

• Photodegradation characteristics of PPCPs in water with UV treatment.

  Environment international 20090701

• Sulphadimethoxine inhibits Phaseolus vulgaris root growth and development of N-fixing nodules.

  Chemosphere 20090701

• Quantification of gait in dystonic Gunn rats.

  Journal of neuroscience methods 20090615

• [Investigation of sulfonamides and tetracyclines antibiotics in soils from various vegetable fields].

  Huan jing ke xue= Huanjing kexue 20090615

• Molecular characterization of tetracycline-resistant genes and integrons from avirulent strains of Escherichia coli isolated from catfish.

  Foodborne pathogens and disease 20090601

• [Effects of antimicrobial drugs on soil microbial respiration].

  Huan jing ke xue= Huanjing kexue 20090515

• Relationships between multidrug-resistant Salmonella enterica Serovar Schwarzengrund and both broiler chickens and retail chicken meats in Japan.

  Japanese journal of infectious diseases 20090501

• A survey of Clostridium spiroforme antimicrobial susceptibility in rabbit breeding.

  Veterinary microbiology 20090414

• Determination of sulfonamide residues in water samples by in-line solid-phase extraction-capillary electrophoresis.

  Journal of chromatography. A 20090410

• Development and validation of a confirmatory method for the determination of sulphonamides in milk by liquid chromatography with diode array detection.

  Analytica chimica acta 20090401

• Determination of ten sulphonamides in egg by liquid chromatography-tandem mass spectrometry.

  Analytica chimica acta 20090401

• Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model.

  Cancer science 20090401

• A multifactorial test of the effects of carotenoid access, food intake and parasite load on the production of ornamental feathers and bill coloration in American goldfinches.

  The Journal of experimental biology 20090401

• Degradation and elimination of various sulfonamides during anaerobic fermentation: a promising step on the way to sustainable pharmacy?

  Environmental science & technology 20090401

• Diagnosis and treatment of Eimeria macusaniensis in an adult alpaca with signs of colic.

  Veterinary journal (London, England : 1997) 20090301

• Pathogen prevalence and influence of composted dairy manure application on antimicrobial resistance profiles of commensal soil bacteria.

  Foodborne pathogens and disease 20090301

• Antimicrobial resistance and genotypic characterization of coagulase-negative staphylococci over the dry period.

  Veterinary microbiology 20090216

• Identification of tumor promotion marker genes for predicting tumor promoting potential of chemicals in BALB/c 3T3 cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20090201

• Calculated free bilirubin levels and neurotoxicity.

  Journal of perinatology : official journal of the California Perinatal Association 20090201

• Determination of sulfadimethoxine and 4N-acetylsulfadimethoxine in bovine plasma, urine, oral fluid, and kidney and liver biopsy samples obtained surgically from standing animals by LC/MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115

• Net changes in antibiotic concentrations downstream from an effluent discharge.

  Journal of environmental quality 20090101

• Efficacy of peritoneal dialysis of tolbutamide in rats under conditions of the plasma unbound fraction being increased.

  Biopharmaceutics & drug disposition 20090101

• Occurrence and elimination of antibiotics at four sewage treatment plants in Japan and their effects on bacterial ammonia oxidation.

  Water science and technology : a journal of the International Association on Water Pollution Research 20090101

• Chronic intermittent diarrhea in a 14-month-old Abyssinian cat.

  The Canadian veterinary journal = La revue veterinaire canadienne 20090101

• Selection of anti-sulfadimidine specific ScFvs from a hybridoma cell by eukaryotic ribosome display.

  PloS one 20090101

• National surveillance of Salmonella enterica in food-producing animals in Japan.

  Acta veterinaria Scandinavica 20090101

• Determination of pharmaceuticals in drinking water by CD-modified MEKC: separation optimization using experimental design.

  Journal of separation science 20081201

• New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity.

  Bioorganic & medicinal chemistry 20081015

• Degradation of estrogenic hormones in a silt loam soil.

  Journal of agricultural and food chemistry 20081008

• Multiresidue determination of sulfonamides in chicken meat by polymer monolith microextraction and capillary zone electrophoresis with field-amplified sample stacking.

  Journal of chromatography. A 20080926

• Acute toxicity evaluation of four antibacterials with Daphnia magna.

  Veterinary research communications 20080901

• Salmonella in healthy pigs: prevalence, serotype diversity and antimicrobial resistance observed during 1998-1999 and 2004-2005 in Japan.

  Epidemiology and infection 20080801

• Hazard assessment of commonly used agricultural antibiotics on aquatic ecosystems.

  Ecotoxicology (London, England) 20080801

• Role of a novel multifunctional excipient poly(ethylene glycol)-block-oligo(vinyl sulfadimethoxine) in controlled release of lysozyme from PLGA microspheres.

  International journal of pharmaceutics 20080624

• Electromyographic characterization in an animal model of dystonia.

  Movement disorders : official journal of the Movement Disorder Society 20080615

• Highly sensitive simultaneous determination of sulfonamide antibiotics and one metabolite in environmental waters by liquid chromatography-quadrupole linear ion trap-mass spectrometry.

  Journal of chromatography. A 20080606

• A reliable high-performance liquid chromatography with ultraviolet detection for the determination of sulfonamides in honey.

  Analytica chimica acta 20080414

• A comparison of the FAST, Premi and KIS tests for screening antibiotic residues in beef kidney juice and serum.

  Analytical and bioanalytical chemistry 20080401

• Comparison of the amounts of endotoxin released from Escherichia coli after exposure to antibiotics and ozone: an in vitro evaluation.

  The Journal of veterinary medical science 20080401

• Effects of ionic strength, temperature, and pH on degradation of selected antibiotics.

  Journal of environmental quality 20080101

• Application of matrix solid-phase dispersion and high-performance liquid chromatography for determination of sulfonamides in honey.

  Journal of AOAC International 20080101

• Sorption of the veterinary antimicrobials sulfadimethoxine and ormetoprim in soil.

  Journal of environmental quality 20080101

• Photodegradation of sulphadimethoxine in water by medium pressure UV lamp.

  Water science and technology : a journal of the International Association on Water Pollution Research 20080101

• Purification of nine sulfonamides from chicken tissues by immunoaffinity chromatography using two monoclonal antibodies.

  Journal of AOAC International 20080101

• Performance of blue-yellow screening test for antimicrobial detection in ovine milk.

  Journal of dairy science 20071201

• New insect system for testing antibiotics.

  The Journal of parasitology 20071201

• Organic solvents-free technique for determining sulfadimethoxine and its metabolites in chicken meat.

  Journal of chromatography. A 20071116

• Determination of sulphonamides in animal tissues by high performance liquid chromatography with pre-column derivatization of 9-fluorenylmethyl chloroformate.

  Journal of separation science 20071101

• Analytical methods for multiresidue determination of sulfonamides and trimethoprim in meat and ground water samples by CE-MS and CE-MS/MS.

  Electrophoresis 20071101

• Cytotoxicity is predicted by unbound and not total bilirubin concentration.

  Pediatric research 20071101

• [Simultaneous determination of nine sulfonamide residues in milk using solid phase extraction and high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20070901

• Determination of residues of sulphonamide in eggs and laying hens.

  Pakistan journal of pharmaceutical sciences 20070701

• Use of sulfadimethoxine in intensive calf farming: evaluation of transfer to stable manure and soil.

  Chemosphere 20070601

• Sulfadimethoxine and ormetoprim residues in three species of fish after oral dosing in feed.

  Journal of aquatic animal health 20070601

• Trace determination of sulfonamides residues in meat with a combination of solid-phase microextraction and liquid chromatography-mass spectrometry.

  Talanta 20070515

• Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea.

  Environment international 20070401

• Validation of an analytical method to determine sulfamides in kidney by HPLC-DAD and PARAFAC2 with first-order derivative chromatograms.

  Analytica chimica acta 20070328

• Development of an immunochromatographic lateral-flow test strip for rapid detection of sulfonamides in eggs and chicken muscles.

  Journal of agricultural and food chemistry 20070321

• Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats.

  Cancer science 20070301

• In-vitro antifungal activities of sulfa drugs against clinical isolates of Aspergillus and Cryptococcus species.

  Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20070101

• Simultaneous determination of 17 sulfonamides and the potentiators ormetoprim and trimethoprim in salmon muscle by liquid chromatography with tandem mass spectrometry detection.

  Journal of AOAC International 20070101

• Determination of 10 sulfonamide residues in meat samples by liquid chromatography with ultraviolet detection.

  Journal of AOAC International 20070101

• Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats.

  Neonatology 20070101

• NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity.

  Neonatology 20070101

• Antimicrobial susceptibility of Shiga toxin-producing Escherichia coli isolated from organic dairy farms, conventional dairy farms, and county fairs in Minnesota.

  Foodborne pathogens and disease 20070101

• Observational study of hepatic cytochrome P-450 protein expression and activity in summer flounder (Paralichtys dentatus) after combination ormetoprim-sulfadimethoxine treatment.

  Chemotherapy 20070101

• Efficacy of eleven antimicrobials against a gregarine parasite (Apicomplexa: Protozoa).

  Annals of clinical microbiology and antimicrobials 20070101

• Characterization of bacterial susceptibility isolates in sixteen dairy farms in Taiwan.

  Journal of dairy science 20061201

• Oxidation of sulfonamide antimicrobials by ferrate(VI) [Fe(VI)O4(2-)].

  Environmental science & technology 20061201

• Determination of sulfonamide antibiotics in wastewater: a comparison of solid phase microextraction and solid phase extraction methods.

  Journal of chromatography. A 20061027

• Determination of antimicrobials in sludge from infiltration basins at two artificial recharge plants by pressurized liquid extraction-liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20061013

• Application of capillary zone electrophoresis with large-volume sample stacking to the sensitive determination of sulfonamides in meat and ground water.

  Electrophoresis 20061001

• Exhaustive extraction of sulfonamide antibiotics from aged agricultural soils using pressurized liquid extraction.

  Journal of chromatography. A 20060922

• Occurrence of sulfonamide antimicrobials in private water wells in Washington County, Idaho, USA.

  Chemosphere 20060901

• Biliverdin-induced brainstem auditory evoked potential abnormalities in the jaundiced Gunn rat.

  Brain research 20060830

• Multiresidue determination of sulfonamides in edible catfish, shrimp and salmon tissues by high-performance liquid chromatography with postcolumn derivatization and fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060818

• Calculated in vivo free bilirubin levels in the central nervous system of Gunn rat pups.

  Pediatric research 20060701

• Oxidation of sulfonamides, macrolides, and carbadox with free chlorine and monochloramine.

  Water research 20060701

• Absence of in vivo genotoxic potential and tumor initiation activity of kojic acid in the rat thyroid.

  Toxicology 20060515

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Evaluation of changes in antimicrobial susceptibility patterns of Pasteurella multocida subsp multocida isolates from pigs in Spain in 1987-1988 and 2003-2004.

  American journal of veterinary research 20060401

• Prevalence and characterization of Escherichia coli O157 isolates from Minnesota dairy farms and county fairs.

  Journal of food protection 20060201

• Degradation kinetics of manure-derived sulfadimethoxine in amended soil.

  Journal of agricultural and food chemistry 20060111

• Comparison of enhancing effects of different goitrogen treatments in combination with beta-estradiol-3-benzoate for establishing a rat two-stage thyroid carcinogenesis model to detect modifying effects of estrogenic compounds.

  Cancer science 20060101

• Sex-specific regional brain bilirubin content in hyperbilirubinemic Gunn rat pups.

  Biology of the neonate 20060101

• Sulfadimethoxine degradation kinetics in manure as affected by initial concentration, moisture, and temperature.

  Journal of environmental quality 20060101

• Simultaneous extraction and analysis of 11 tetracycline and sulfonamide antibiotics in influent and effluent domestic wastewater by solid-phase extraction and liquid chromatography-electrospray ionization tandem mass spectrometry.

  Journal of chromatography. A 20051202

• The jaundiced gunn rat model of auditory neuropathy/dyssynchrony.

  The Laryngoscope 20051201

• Determination of pKa values by capillary zone electrophoresis with a dynamic coating procedure.

  Journal of separation science 20051101

• [Determination of residual sulfonamides in meat by high performance liquid chromatography with solid-phase extraction].

  Se pu = Chinese journal of chromatography 20051101

• Actinomyces naeslundii infection in an African hedgehog (Atelerix albiventris) with mandibular osteomyelitis and cellulitis.

  The Veterinary record 20051008

• Simultaneous determination of sulfamonomethoxine, sulfadimethoxine, and their hydroxy/N(4)-acetyl metabolites with gradient liquid chromatography in chicken plasma, tissues, and eggs.

  Talanta 20050715

• [Qualification and quantification of 10 sulfonamides in animal feedstuff by high performance liquid chromatography-electrospray tandem mass spectrometry].

  Se pu = Chinese journal of chromatography 20050701

• Effect of selective cyclooxygenase-2 inhibitors on heart rate in healthy young men.

  The American journal of cardiology 20050615

• Triplet-sensitized photodegradation of sulfa drugs containing six-membered heterocyclic groups: identification of an SO2 extrusion photoproduct.

  Environmental science & technology 20050515

• Nephrotic syndrome associated with administration of sulfadimethoxine/ormetoprim in a dobermann.

  The Journal of small animal practice 20050501

• Microbial inhibition by pharmaceutical antibiotics in different soils--dose-response relations determined with the iron(III) reduction test.

  Environmental toxicology and chemistry 20050401

• Development of invasive follicular cell carcinomas in a rat thyroid carcinogenesis model: biological impact of capsular inflammation and reduced cyclooxygenase-2 expression.

  Cancer science 20050101

• Confirmation of sulfamethazine, sulfathiazole, and sulfadimethoxine residues in condensed milk and soft-cheese products by liquid chromatography/tandem mass spectrometry.

  Journal of AOAC International 20050101

• Simultaneous determination of 16 sulfonamides in honey by liquid chromatography/tandem mass spectrometry.

  Journal of AOAC International 20050101

• Evaluation of antimicrobial agents for veterinary use in the ecotoxicity test using microalgae.

  Chemosphere 20041201

• Intestinal microflora in 45 crows in Ueno Zoo and the in vitro susceptibilities of 29 Escherichia coli isolates to 14 antimicrobial agents.

  The Journal of veterinary medical science 20041001

• Comparative efficacy of enrofloxacin, oxytetracycline, and sulfadimethoxine for the control of morbidity and mortality caused by Escherichia coli in broiler chickens.

  Avian diseases 20040901

• Robustness of the extraction step when parallel factor analysis (PARAFAC) is used to quantify sulfonamides in kidney by high performance liquid chromatography-diode array detection (HPLC-DAD).

  The Analyst 20040801

• Effects of pig slurry on the sorption of sulfonamide antibiotics in soil.

  Archives of environmental contamination and toxicology 20040701

• Idiosyncratic toxicity associated with potentiated sulfonamides in the dog.

  Journal of veterinary pharmacology and therapeutics 20040601

• Validation of a confirmatory method for the determination of sulphonamides in muscle according to the European Union regulation 2002/657/EC.

  Journal of chromatography. A 20040402

• Intramolecular isobaric fragmentation: a curiosity of accurate mass analysis of sulfadimethoxine in pond water.

  Analytical chemistry 20040301

• [Determination of the residues of five sulfa drugs in eel by HPLC].

  Se pu = Chinese journal of chromatography 20040301

• Application of shielded column liquid chromatography for determination of sulfamonomethoxine, sulfadimethoxine, and their N4-acetyl metabolites in milk.

  Journal of chromatography. A 20040227

• Pharmacokinetics of sulfadimethoxine and ormetoprim in a 5:1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis).

  Journal of veterinary pharmacology and therapeutics 20040201

• Acute columnaris infection in channel catfish, Ictalurus punctatus (Rafinesque): efficacy of practical treatments for warmwater aquaculture ponds.

  Journal of fish diseases 20040101

• Sequential analysis of development of invasive thyroid follicular cell carcinomas in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation.

  Toxicologic pathology 20040101

• Specificity of co-promoting effects of caffeine on thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine.

  Toxicologic pathology 20040101

• Sorption of sulfonamide pharmaceutical antibiotics on whole soils and particle-size fractions.

  Journal of environmental quality 20040101

• pH-dependent elution profiles of selected proteins in HPLC having a stationary phase modified with pH-sensitive sulfonamide polymers.

  Journal of biomaterials science. Polymer edition 20040101

• Determination of sulfonamide residues in the tissues of food animals using automated precolumn derivatization and liquid chromatography with fluorescence detection.

  Journal of AOAC International 20040101

• Pharmacokinetics of quinacrine in the treatment of prion disease.

  BMC infectious diseases 20040101

• Effects of sodium chlorate on antibiotic resistance in Escherichia coli O157:H7.

  Foodborne pathogens and disease 20040101

• Determination of some sulfonamides and trimethoprim in chicken, fish muscle and eggs by liquid chromatography-tandem mass spectrometry.

  Veterinaria italiana 20040101

• Liquid chromatography-fluorescence detection for simultaneous analysis of sulfonamide residues in honey.

  Analytical and bioanalytical chemistry 20030601

• Disposition of sulfadimethoxine in male llamas (Llama glama) after single intravenous and oral administrations.

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20030301

• A national surveillance of antimicrobial resistance in Escherichia coli isolated from food-producing animals in Japan.

  The Journal of antimicrobial chemotherapy 20030201

• Characterization of a Cu(II) complex of sulfadimethoxine.

  Journal of inorganic biochemistry 20030201

• Resistance of bacterial isolates from poultry products to therapeutic veterinary antibiotics.

  Journal of food protection 20030101

• Survey of residual tetracycline antibiotics and sulfa drugs in kidneys of diseased animals in the Aichi Prefecture, Japan (1995-1999).

  Journal of AOAC International 20030101

• Somatosensory and brainstem auditory evoked potentials in the Gunn rat model of acute bilirubin neurotoxicity.

  Pediatric research 20021201

• Penetration of drug resistance in Escherichia coli isolated from laboratory animals.

  The Journal of veterinary medical science 20021201

• Efficacy of oral sulfadimethoxine against two gregarine parasites, Protomagalhaensia granulosae and Gregarina cubensis (Apicomplexa: Eugregarinida), infecting the Death's Head cockroach, Blaberus discoidalis.

  The Journal of parasitology 20020801

• Comparison of ion-pairing and ion-suppressing liquid chromatographic methods for the determination of pyrimethamine and ormetoprim in chicken feed.

  Journal of chromatographic science 20020701

• Sulphadimethoxine and Azolla filiculoides Lam.: a model for drug remediation.

  Water research 20020701

• Self-assembled hydrogel nanoparticles responsive to tumor extracellular pH from pullulan derivative/sulfonamide conjugate: characterization, aggregation, and adriamycin release in vitro.

  Pharmaceutical research 20020501

• Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats.

  Cancer letters 20020408

• Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry.

  Journal of chromatography. A 20020405

• Sulphonamide residues in eggs following drug administration via the drinking water.

  Food additives and contaminants 20020401

• Sulfadimethoxine and rhodamine B as oral biomarkers for European badgers (Meles meles).

  Journal of wildlife diseases 20020401

• Antibiotic susceptibility patterns for environmental streptococci isolated from bovine mastitis in central California dairies.

  Journal of dairy science 20020101

• Determination of sulfonamide residues in eggs by liquid chromatography.

  Journal of AOAC International 20020101

• Quantitative determination of sulfonamide in meat by liquid chromatography-electrospray-mass spectrometry.

  Talanta 20011224

• Effect of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in newborn piglets.

  Brain research 20011220

• Matrix solid-phase dispersion extraction and high-performance liquid chromatographic determination of residual sulfonamides in chicken.

  Journal of chromatography. A 20011207

• Transference of dietary veterinary drugs into eggs.

  Veterinary research communications 20011201

• High-performance liquid chromatographic procedure for routine residue monitoring of seven sulfonamides in milk.

  Fresenius' journal of analytical chemistry 20011201

• Disposition of sulfadimethoxine in camels (Camelus dromedarius) following single intravenous and oral doses.

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20011201

• Pharmacokinetics of sulfadimethoxine and sulfamethoxazole in combination with trimethoprim after oral single- and multiple-dose administration to healthy pigs.

  Veterinary research communications 20010801

• Synergistic effects of high-dose soybean intake with iodine deficiency, but not sulfadimethoxine or phenobarbital, on rat thyroid proliferation.

  Japanese journal of cancer research : Gann 20010401

• In vitro hepatobiotransformation of sulphadimethoxine in laying hens.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010401

• Antimicrobial susceptibilities of Erysipelothrix rhusiopathiae isolated from pigs with swine erysipelas in Japan, 1988-1998.

  Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20010301

• Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.

  Annals of tropical medicine and parasitology 19961201

• Monodrug efficacies of sulfonamides in prophylaxis for Pneumocystis carinii pneumonia.

  Antimicrobial agents and chemotherapy 19960401

• [Modifying effects of goitrogens on the tumor development in the liver and lung of rats].

  Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 19960101

• Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs.

  Antimicrobial agents and chemotherapy 19950801

• Assessment of candidate anticryptosporidial agents in an immunosuppressed rat model.

  The Journal of infectious diseases 19930301

• Activity of sulfadimethoxine against cryptosporidiosis in dairy calves.

  The Journal of parasitology 19920601

• Anticryptosporidial activity is associated with specific sulfonamides in immunosuppressed rats.

  The Journal of parasitology 19910401

• Anti-cryptosporidial drug activity screened with an immunosuppressed rat model.

  The Journal of protozoology 19910101

• Drugs as allergens: detection and combining site specificities of IgE antibodies to sulfamethoxazole.

  Molecular immunology 19881201

• [Noncholinesterase component in the molecular mechanism of action of the cholinesterase reactivator dipyroxime].

  Biulleten' eksperimental'noi biologii i meditsiny 19820601