1220219-73-7 | 3-Chloro-2-fluoropyridine-5-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$50.00	$35.00
1g	95%	in stock	$135.00	$95.00
10g	95%	in stock	$1,286.00	$900.00
25g	95%	in stock	$2,530.00	$1,771.00

Description

• Catalog Number: AA55060
• Chemical Name: 3-Chloro-2-fluoropyridine-5-boronic acid, pinacol ester
• CAS Number: 1220219-73-7
• Molecular Formula: C11H14BClFNO2
• Molecular Weight: 257.4968
• MDL Number: MFCD16995268
• SMILES: Fc1ncc(cc1Cl)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 287
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1

Upstream Synthesis Route

3-Chloro-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a highly versatile compound that finds frequent application in the realm of chemical synthesis. Its unique structure and properties make it an invaluable tool for organic chemists looking to introduce specific functionalities into their target molecules.One key application of 3-Chloro-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is in cross-coupling reactions, particularly Suzuki-Miyaura coupling. In this process, the compound serves as a boronic acid derivative, allowing for efficient and selective carbon-carbon bond formation. This reaction is widely used in medicinal chemistry, material science, and other fields where precise control over chemical structure is paramount.Additionally, 3-Chloro-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine can be employed as a versatile building block for the synthesis of pharmaceuticals, agrochemicals, and various functional materials. Its fluorine and boron functionalities enable chemists to modify molecules in a controlled and predictable manner, facilitating the creation of complex structures with high efficiency.Overall, the use of 3-Chloro-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine in chemical synthesis empowers researchers to access a wide range of novel compounds and materials, making it an indispensable tool in the modern synthetic chemistry toolkit.