123171-59-5 | Cefepime Dihydrochloride Monohydrate

Packsize	Purity	Availability	Price	Discounted Price
1mg	90%	in stock	$15.00	$10.00
250mg	90%	in stock	$30.00	$21.00
1g	90%	in stock	$38.00	$26.00
5g	90%	in stock	$105.00	$73.00
25g	90%	in stock	$383.00	$268.00
100g	90%	in stock	$1,383.00	$968.00
250g	90%	in stock	$3,155.00	$2,208.00

Description

• Catalog Number: AA25856
• Chemical Name: Cefepime Dihydrochloride Monohydrate
• CAS Number: 123171-59-5
• Molecular Formula: C19H28Cl2N6O6S2
• Molecular Weight: 571.4982200000001
• MDL Number: MFCD06795759
• SMILES: CON=C(c1csc(n1)N)C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C[N+]1(C)CCCC1.[Cl-].Cl.O

Computed Properties

• Complexity: 874
• Covalently-Bonded Unit Count: 4
• Defined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 35
• Hydrogen Bond Acceptor Count: 12
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 7

Literature

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  The American journal of emergency medicine 20120901

• Extended-spectrum β-lactamase producers reported as susceptible to piperacillin-tazobactam, cefepime, and cefuroxime in the era of lowered breakpoints and no confirmatory tests.

  Infection control and hospital epidemiology 20120801

• AmpC β-lactamases in nosocomial isolates of Klebsiella pneumoniae from India.

  The Indian journal of medical research 20120801

• Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin.

  Clinical biochemistry 20120701

• Cefepime: a rare cause of encephalopathy.

  Internal medicine journal 20120601

• Blood and CSF monitoring of cefepime-induced neurotoxicity: nine case reports.

  The Journal of antimicrobial chemotherapy 20120501

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  Obesity surgery 20120301

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  The Journal of antimicrobial chemotherapy 20120101

• Infection from an exfoliating primary tooth in a child with severe neutropenia: a case report.

  Pediatric dentistry 20120101

• Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044.

  PloS one 20120101

• Animal model methodology: immunocompetent or leucopenic rats, which is the best? Results from a model of experimental pneumonia due to derepressed cephalosporinase-producing Enterobacter cloacae.

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  Revista Argentina de microbiologia 20120101

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• Mechanisms of resistance in clinical isolates of Pseudomonas aeruginosa less susceptible to cefepime than to ceftazidime.

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• Effect of spacer sequences between bla(CTX-M) and ISEcp1 on bla(CTX-M) expression.

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  International journal of clinical pharmacy 20111201

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  JPMA. The Journal of the Pakistan Medical Association 20110101

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  Journal of chemotherapy (Florence, Italy) 20080801

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  Indian journal of medical microbiology 20080101

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  The Indian journal of medical research 20080101

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  International journal of antimicrobial agents 20070901

• Comparison of the probability of target attainment between ceftriaxone and cefepime in the cerebrospinal fluid and serum against Streptococcus pneumoniae.

  Diagnostic microbiology and infectious disease 20070801

• Blood-brain barrier penetration of cefepime after neurosurgery.

  Chinese medical journal 20070705

• A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation.

  Bone marrow transplantation 20070701

• Cefepime plus amikacin as an initial empirical therapy of febrile neutropenia in paediatric cancer patients.

  Singapore medical journal 20070701

• Could geriatric comprehensive assessment predict the outcome of pneumonia in the very old?

  Age and ageing 20070701

• Simultaneous determination of cefepime and vancomycin in plasma and cerebrospinal fluid by MEKC with direct sample injection and application for bacterial meningitis.

  Electrophoresis 20070601

• Use of cefepime for the treatment of infections caused by extended spectrum: beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

  Singapore medical journal 20070601

• A randomized prospective study of cefepime plus metronidazole with imipenem-cilastatin in the treatment of intra-abdominal infections.

  Infection 20070601

• Cefepime-induced encephalopathy with triphasic waves in three Asian patients.

  Annals of the Academy of Medicine, Singapore 20070601

• [Emergence of beta-lactam-dependent Bacillus cereus associated with prolonged treatment with cefepime in a neutropenic patient].

  The Korean journal of laboratory medicine 20070601

• Cefepime pharmacodynamics in patients with extended spectrum beta-lactamase (ESBL) and non-ESBL infections.

  The Journal of infection 20070501

• Cefepime cerebrospinal fluid concentrations in neonatal bacterial meningitis.

  The Annals of pharmacotherapy 20070501

• Efficacy and safety of cefepime: a systematic review and meta-analysis.

  The Lancet. Infectious diseases 20070501

• Once-daily cefepime versus ceftriaxone for nursing home-acquired pneumonia.

  Journal of the American Geriatrics Society 20070501

• [Cefepime and aztreonam shortages: we've run out of ammo].

  Enfermedades infecciosas y microbiologia clinica 20070501

• Molecular epidemiology and characterization of resistance mechanisms to various antimicrobial agents in Acinetobacter baumannii isolated in Mérida, Venezuela.

  Medical science monitor : international medical journal of experimental and clinical research 20070401

• Cefepime restriction improves gram-negative overall resistance patterns in neonatal intensive care unit.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20070401

• Bactericidal activity of cefepime and ceftriaxone tested against Streptococcus pneumoniae.

  Diagnostic microbiology and infectious disease 20070301

• Comparative activities of cefepime and piperacillin/tazobactam tested against a global collection of Escherichia coli and Klebsiella spp. with an ESBL phenotype.

  Diagnostic microbiology and infectious disease 20070301

• Piperacillin/tazobactam-induced seizure rapidly reversed by high flux hemodialysis in a patient on peritoneal dialysis.

  The American journal of the medical sciences 20070301

• Comparative in vivo efficacy of meropenem, imipenem, and cefepime against Pseudomonas aeruginosa expressing MexA-MexB-OprM efflux pumps.

  Diagnostic microbiology and infectious disease 20070201

• Cefepime versus ceftazidime: considerations for empirical use in critically ill patients.

  International journal of antimicrobial agents 20070201

• Pasteurella multocida sepsis, due to a scratch from a pet cat, in a post-chemotherapy neutropenic patient with non-Hodgkin lymphoma.

  International journal of hematology 20070201

• Breakthrough infection of Trichosporon asahii in a patient with chronic lymphocytic leukemia.

  International journal of hematology 20070201

• Escherichia coli aortic valve endocarditis.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070201

• Comparisons of parenteral broad-spectrum cephalosporins tested against bacterial isolates from pediatric patients: report from the SENTRY Antimicrobial Surveillance Program (1998-2004).

  Diagnostic microbiology and infectious disease 20070101

• Carbapenem-resistant Acinetobacter baumannii: an emerging threat for patients with post-neurosurgical meningitis.

  International journal of antimicrobial agents 20070101

• Acute-phase response alters the disposition kinetics of cefepime following intravenous administration to rabbits.

  Veterinary research communications 20070101

• High-risk febrile neutropenia in Auckland 2003-2004: the influence of the microbiology laboratory on patient treatment and the use of pathogen-specific therapy.

  Internal medicine journal 20070101

• Inhibitory effects of ofloxacin and cefepime on enzyme activity of 6-phosphogluconate dehydrogenase from chicken liver.

  Protein and peptide letters 20070101

• Selective immediate hypersensitivity to cefepime.

  Journal of investigational allergology & clinical immunology 20070101

• Outpatient intravenous antibiotics for methicillin-resistant Staphylococcus aureus sinusitis.

  American journal of rhinology 20070101

• [In vitro activity of ertapenem against staphylococci].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101

• [Efficacy of cefixime and cefepime vs. other cephalosporins in experimental plague of albino mice due to variants FI+ and FI- of the plague microbe].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101

• Cefepime monotherapy for treatment of febrile neutropenia in children.

  Journal of paediatrics and child health 20061201

• Randomized study of cefepime versus ceftazidime plus amikacin in patients with solid tumors treated with high dose chemotherapy (HDC) and peripheral blood stem cell support (PBSCS) with febrile neutropenia.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061201

• Acute neurological deficits caused by cefipime: a case report and review of literature.

  Acta neurologica Taiwanica 20061201

• Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units.

  The Journal of antimicrobial chemotherapy 20061101

• Pyogenic liver abscess: Klebsiella as an emerging pathogen.

  Emergency radiology 20061101

• In vitro activity of cefepime combined with sulbactam against clinical isolates of carbapenem-resistant Acinetobacter spp.

  International journal of antimicrobial agents 20061101

• Optimising antibiotic dosing regimens based on pharmacodynamic target attainment against Pseudomonas aeruginosa collected in Hungarian hospitals.

  International journal of antimicrobial agents 20061101

• Antibiotic-resistance patterns and frequency of extended-spectrum beta-lactamase-producing isolates of Klebsiella pneumoniae in Tehran.

  Medical science monitor : international medical journal of experimental and clinical research 20061101

• Use of cefepime for the treatment of infections caused by extended spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

  Diagnostic microbiology and infectious disease 20061101

• Phenotypic and genotypic detection of ESBL mediated cephalosporin resistance in Klebsiella pneumoniae: emergence of high resistance against cefepime, the fourth generation cephalosporin.

  The Journal of infection 20061001

• Stability of cefepime and metronidazole prepared for simplified administration as a single product.

  Diagnostic microbiology and infectious disease 20061001

• Evaluating broad-spectrum antimicrobials.

  QJM : monthly journal of the Association of Physicians 20061001

• Treatment of bone and joint infections caused by Gram-negative bacilli with a cefepime-fluoroquinolone combination.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20061001

• Ertapenem versus cefepime for initial empirical treatment of pneumonia acquired in skilled-care facilities or in hospitals outside the intensive care unit.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20061001

• Emergence of cefotaxime resistance in Citrobacter freundii causing necrotizing fasciitis and osteomyelitis.

  The Journal of infection 20060901

• Antimicrobial activity of cefepime tested against ceftazidime-resistant Gram-negative clinical strains from North American Hospitals: report from the SENTRY Antimicrobial Surveillance Program (1998-2004).

  Diagnostic microbiology and infectious disease 20060901

• Errors committed by nursing technicians and assistants in administering antibiotics.

  American journal of infection control 20060901

• A randomized, open-label, multicenter comparative study of the efficacy and safety of piperacillin-tazobactam and cefepime for the empirical treatment of febrile neutropenic episodes in patients with hematologic malignancies.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060815

• Cefepime neurotoxicity: case report, pharmacokinetic considerations, and literature review.

  Pharmacotherapy 20060801

• Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy.

  Leukemia & lymphoma 20060801

• Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function.

  Neurology 20060725

• Treatment of cavitary pulmonary zygomycosis with surgical resection and posaconazole.

  The Annals of thoracic surgery 20060701

• The effect of different doses of cisplatin on the pharmacokinetic parameters of cefepime in mice.

  Laboratory animals 20060701

• Application of the ion pair concept to the n-octanol-water partitioning of cefepime and cefpirome.

  International journal of pharmaceutics 20060619

• Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits.

  Journal of veterinary science 20060601

• Prospective drug utilization evaluation of three broad-spectrum antimicrobials: cefepime, piperacillin-tazobactam and meropenem.

  QJM : monthly journal of the Association of Physicians 20060601

• In vivo selection of Enterobacter aerogenes with reduced susceptibility to cefepime and carbapenems associated with decreased expression of a 40 kDa outer membrane protein and hyperproduction of AmpC beta-lactamase.

  International journal of antimicrobial agents 20060601

• Clinical experiences of the infections caused by extended-spectrum beta-lactamase-producing Serratia marcescens at a medical center in Taiwan.

  Japanese journal of infectious diseases 20060601

• Cefepime vs. Ampicillin/Sulbactam and Aztreonam as antibiotic prophylaxis in neurosurgical patients with external ventricular drain: result of a prospective randomized controlled clinical trial.

  Journal of clinical pharmacy and therapeutics 20060601

• [Efficacies of ceftazidime and cefepime in rats with experimental pneumonia caused by extended-spectrum beta-lactamase-producing strain of Klebsiella pneumonia].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20060601

• Pilot study of continuous infusion cefepime in adult patients with cystic fibrosis.

  The Journal of antimicrobial chemotherapy 20060501

• Extended-spectrum beta-lactamases and clinical outcomes: current data.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415

• Pharmacokinetics of cefepime in bile and gall bladder tissue after prophylactic administration in patients with extrahepatic biliary diseases.

  International journal of antimicrobial agents 20060401

• Pharmacodynamic profiling of cefepime in plasma and cerebrospinal fluid of hospitalized patients with external ventriculostomies.

  Diagnostic microbiology and infectious disease 20060301

• [Maxipime in the treatment of neonatal sepsis].

  Georgian medical news 20060301

• Trimethoprim-sulfamethoxazole induced rash and fatal hematologic disorders.

  The Journal of infection 20060201

• Nonconvulsive status epilepticus due to cefepime in a patient with normal renal function.

  Epilepsy & behavior : E&B 20060201

• Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials.

  The Journal of antimicrobial chemotherapy 20060201

• Trough serum concentrations of beta-lactam antibiotics in cancer patients: inappropriateness of conventional schedules to pharmacokinetic/pharmacodynamic properties of beta-lactams.

  International journal of antimicrobial agents 20060201

• [The combination effects of antibacterial agents against clinical isolated multiple-drug resistant Pseudomonas aeruginosa].

  The Japanese journal of antibiotics 20060201

• High-dose cefepime as an alternative treatment for infections caused by TEM-24 ESBL-producing Enterobacter aerogenes in severely-ill patients.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060101

• Detection of a novel variant bla(CTX-M-3) extended spectrum beta-lactamase gene in a community-acquired Escherichia coli isolate.

  Scandinavian journal of infectious diseases 20060101

• Monotherapy with piperacillin/tazobactam versus cefepime as empirical therapy for febrile neutropenia in pediatric cancer patients: a randomized comparison.

  Pediatric hematology and oncology 20060101

• Experience with cefepime versus meropenem as empiric monotherapy for neutropenia and fever in pediatric patients with solid tumors.

  Pediatric hematology and oncology 20060101

• Febrile neutropenia as the presenting sign of appendicitis in an adolescent with acute myelogenous leukemia.

  Pediatric hematology and oncology 20060101

• [Cefepime as an empiric treatment of febrile neutropenia in patients after high dose therapy and autologous stem cell transplantation].

  Casopis lekaru ceskych 20060101

• [Antimicrobial susceptibility of phenotypically extended spectrum beta-lactamase producing Pseudomonas aeruginosa and Acinetobacter baumannii isolates].

  Mikrobiyoloji bulteni 20060101

• Modified double-disc test for detection of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae.

  British journal of biomedical science 20060101

• Development and in-house validation of a microbiological assay for determination of cefepime in injectable preparations.

  Journal of AOAC International 20060101

• Nonsurgical treatment of bilateral emphysematous pyelonephritis in a diabetic patient.

  Journal of nephrology 20060101

• [Resistance to cefepime in Enterobacter cloacae isolates from hospitals in Bogotá, Colombia].

  Revista de salud publica (Bogota, Colombia) 20060101

• Staphylococcal scalded skin syndrome: a rare complication of a common pathogen.

  The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20060101

• Antimicrobial susceptibility of Staphylococcus aureus isolated from colonized hospital personnel.

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101

• Susceptibility of Klebsiella spp. to cefpirome and cefepime.

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101

• Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function.

  Neurology 20051213

• Pharmacokinetics of cefepime administered by i.v. and i.m. routes to ewes.

  Journal of veterinary pharmacology and therapeutics 20051201

• Case of the month. Chronic recurrent multifocal osteomyelitis.

  JAAPA : official journal of the American Academy of Physician Assistants 20051201

• Pseudomonas aeruginosa infective endocarditis presenting as bacterial meningitis.

  The Journal of infection 20051101

• Simultaneous determination of cefepime and L-arginine by micellar electrokinetic chromatography and applications to commercial injections.

  Journal of separation science 20051101

• Effect of cefepime on startle amplitude and prepulse inhibition of startle reflex in rats: manipulation of GABAA receptor function with midazolam.

  Methods and findings in experimental and clinical pharmacology 20051101

• Determination of ceftazidime and cefepime in plasma and dialysate-ultrafiltrate from patients undergoing continuous veno-venous hemodiafiltration by HPLC.

  Journal of pharmaceutical and biomedical analysis 20051004

• Pharmacodynamics of antimicrobials for the empirical treatment of nosocomial pneumonia: a report from the OPTAMA Program.

  Critical care medicine 20051001

• Clinical implications of extended spectrum beta-lactamase (ESBL) producing Klebsiella species and Escherichia coli on cefepime effectiveness.

  The Journal of infection 20051001

• Effects of hyperbaric oxygen treatment on liver functions, oxidative status and histology in septic rats.

  Intensive care medicine 20050901

• Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050901

• Cephalosporin-induced nonconvulsive status epilepticus: clinical and electroencephalographic features.

  Epilepsia 20050901

• [Therapeutic effects of cefepime and sulbactam/cefoperazone on moderate and severe respiratory tract infection in children].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050901

• Pan-drug-resistant Pseudomonas aeruginosa causing nosocomial infection at a university hospital in Taiwan.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050801

• Pharmacodynamics of intermittent and continuous infusion piperacillin/tazobactam and cefepime against extended-spectrum beta-lactamase-producing organisms.

  International journal of antimicrobial agents 20050801

• Cefepime in critically ill patients: continuous infusion vs. an intermittent dosing regimen.

  International journal of clinical pharmacology and therapeutics 20050801

• Subcutaneous administration of cefepime.

  Journal of pain and symptom management 20050801

• Comparative study of the disposition of levofloxacin, netilmicin and cefepime in the isolated rat lung.

  The Journal of pharmacy and pharmacology 20050701

• Potency and spectrum trends for cefepime tested against 65746 clinical bacterial isolates collected in North American medical centers: results from the SENTRY Antimicrobial Surveillance Program (1998-2003).

  Diagnostic microbiology and infectious disease 20050701

• [Comparison of different phenotypic methods detecting extended spectrum beta-lactamases in Pseudomonas aeruginosa and Acinetobacter baumannii strains].

  Mikrobiyoloji bulteni 20050701

• Reevaluation of the cefepime minimal inhibitory concentrations and disk diffusion test zone diameter relationship for a worldwide collection of Enterobacteriaceae enriched for extended-spectrum beta-lactamase-producing organisms.

  Diagnostic microbiology and infectious disease 20050601

• Continuous infusion beta-lactams for intensive care unit pulmonary infections.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050501

• Comprehensive in vitro evaluation of cefepime combined with aztreonam or ampicillin/sulbactam against multi-drug resistant Pseudomonas aeruginosa and Acinetobacter spp.

  International journal of antimicrobial agents 20050501

• Cefepime and continuous renal replacement therapy (CRRT): in vitro permeability of two CRRT membranes and pharmacokinetics in four critically ill patients.

  Clinical therapeutics 20050501

• Intermittent administration of betalactam-antibiotics for treatment of severe infection in hemodialysis patients.

  European journal of medical research 20050420

• Occurrence of extended-spectrum beta-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteria.

  Diagnostic microbiology and infectious disease 20050401

• [Rapid identification of the isomeric impurity in raw drug of cefepime dihydrochloride by liquid chromatography-tandem mass spectrometry].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050401

• [Cefepime-induced encephalopathy: clinical and electroencephalographic features in seven patients].

  Arquivos de neuro-psiquiatria 20050301

• Spontaneous adrenal hemorrhage during pregnancy: a review of the literature and a case report of successful conservative management.

  Obstetrical & gynecological survey 20050301

• Comparative activity of oral and parenteral cephalosporins tested against multidrug-resistant Streptococcus pneumoniae: report from the SENTRY Antimicrobial Surveillance Program (1997-2003).

  Diagnostic microbiology and infectious disease 20050201

• Activity of cefepime and carbapenems in experimental pneumonia caused by porin-deficient Klebsiella pneumoniae producing FOX-5 beta-lactamase.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050101

• Disposition kinetics, bioavailability and renal clearance of cefepime in calves.

  Veterinary research communications 20050101

• Pharmacokinetics of intraperitoneal cefepime in automated peritoneal dialysis.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101

• [Images in medicine. Multiple brain abscess ].

  Revista da Associacao Medica Brasileira (1992) 20050101

• [Efficacy and safety of cefepime in the treatment of bronchopulmonary disease exacerbation in pediatric patients with mucoviscidosis].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

• [Role of cefepime in the treatment of hospital-acquired pneumonia].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

• [In vitro activity of cefepime against ESBL-positive clinical strains of gram-negative rods].

  Medycyna doswiadczalna i mikrobiologia 20050101

• Cefepime and the inoculum effect in tests with Klebsiella pneumoniae producing plasmid-mediated AmpC-type beta-lactamase.

  The Journal of antimicrobial chemotherapy 20041201

• Stability of cefepime in icodextrin peritoneal dialysis solution.

  The Annals of pharmacotherapy 20041201

• Treating serious infections: focus on cefepime.

  Pharmacotherapy 20041201

• Left atrial myxoma prolapsing into the left ventricle. Case report and review of the literature.

  Chemotherapy 20041201

• [Endocarditis due to the Neisseria elongata subspecies nitroreducens].

  Enfermedades infecciosas y microbiologia clinica 20041101

• Relationship between pharmacokinetics and pharmacodynamics of beta-lactams and outcome.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20041101

• In vitro activity of cefepime and cefpirome compared to other third-generation cephem antibiotics against gram-negative nosocomial pathogens.

  Die Pharmazie 20041101

• Comparison of in vivo intrinsic activity of cefepime and imipenem in a Pseudomonas aeruginosa rabbit endocarditis model: effect of combination with tobramycin simulating human serum pharmacokinetics.

  The Journal of antimicrobial chemotherapy 20041001

• An adult case of Chryseobacterium meningosepticum meningitis.

  Japanese journal of infectious diseases 20041001

• Simultaneous determination of cefepime and grepafloxacin in human urine by high-performance liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20040921

• Beta-lactam antibiotics: newer formulations and newer agents.

  Infectious disease clinics of North America 20040901

• [Cefepime-associated encephalopathy in a patient with septic shock and renal failure].

  Revista clinica espanola 20040901

• Antimicrobial susceptibility survey of Pseudomonas aeruginosa strains isolated from clinical sources.

  Journal of the National Medical Association 20040801

• Randomized trial of cefepime monotherapy or cefepime in combination with amikacin as empirical therapy for febrile neutropenia.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040715

• Monotherapy versus dual therapy based on risk categorization of febrile neutropenic patients.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040715

• Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger?

  Annals of hematology 20040701

• Evaluation of a new cefepime-clavulanate ESBL Etest to detect extended-spectrum beta-lactamases in an Enterobacteriaceae strain collection.

  The Journal of antimicrobial chemotherapy 20040701

• Comparison of 99mTc-DTPA and urea for measuring cefepime concentrations in epithelial lining fluid.

  The European respiratory journal 20040701

• Case report: Pseudomonas aeruginosa-related intervertebral discitis in a young boy with medulloblastoma.

  Journal of neuro-oncology 20040701

• Determination of cefepime in plasma and cerebrospinal fluid by micellar electrokinetic chromatography with direct sample injection.

  Electrophoresis 20040601

• In vitro activities of beta-lactam antibiotics alone and in combination with sulbactam against Gram-negative bacteria.

  International journal of antimicrobial agents 20040601

• Retrospective study of clinical outcomes with extended-spectrum beta-lactamases--a different interpretation.

  Pharmacotherapy 20040601

• In vitro activities of antibiotic combinations against clincal isolates of Pseudomonas aeruginosa.

  The Kaohsiung journal of medical sciences 20040601

• Resistance to imipenem, cefepime, and cefpirome associated with mutation in Omp36 osmoporin of Enterobacter aerogenes.

  Biochemical and biophysical research communications 20040507

• Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition.

  FEMS microbiology letters 20040501

• Comparison of the double-disk, combined disk, and Etest methods for detecting metallo-beta-lactamases in gram-negative bacilli.

  Diagnostic microbiology and infectious disease 20040501

• In vitro killing of parenteral beta-lactams against standard and high inocula of extended-spectrum beta-lactamase and non-ESBL producing Klebsiella pneumoniae.

  Diagnostic microbiology and infectious disease 20040501

• Intrapulmonary concentrations of cefepime.

  Critical care medicine 20040501

• Reversible coma secondary to cefepime neurotoxicity.

  The Annals of pharmacotherapy 20040401

• Cefepime-induced non-convulsive status epilepticus in a peritoneal dialysis patient.

  Pediatric nephrology (Berlin, Germany) 20040401

• Cefepime vs. Meropenem as empirical therapy for neutropenic fever in children with lymphoma and solid tumours.

  Pediatric blood & cancer 20040301

• A case of IgE-mediated hypersensitivity to cefepime.

  Allergy 20040201

• Cefepime-induced encephalopathy.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20040101

• Nonconvulsive status epilepticus associated with cefepime in a patient undergoing autologous stem cell transplantation.

  Bone marrow transplantation 20040101

• Cefepime versus ceftazidime for treatment of pneumonia.

  The Journal of international medical research 20040101

• [3-Year experience of use of cefepime (Maxipime) for the treatment of hospital infections in a specialized surgical hospital].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

• A prospective, randomized study comparing cefepime and imipenem-cilastatin in the empirical treatment of febrile neutropenia in patients treated for haematological malignancies.

  Scandinavian journal of infectious diseases 20040101

• [Risk factors of pseudomonas infection in hemoblastosis patients].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20040101

• The cost-effectiveness of cefepime plus metronidazole versus imipenem/cilastatin in the treatment of complicated intra-abdominal infection.

  Surgical infections 20040101

• [Respiratory fluoroquinolones in the treatment of exacerbations of chronic obstructive lung disease].

  Problemy tuberkuleza i boleznei legkikh 20040101

• [Imipenem and cefepime in empirical therapy of infectious complications after radical surgeries in patients with invasive cancer of the urinary bladder].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

• [Study of cefepime in Russia].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

• In vitro activity of combination therapy with cefepime, piperacillin-tazobactam, or meropenem with ciprofloxacin against multidrug-resistant Pseudomonas aeruginosa strains.

  Chemotherapy 20031201

• In vitro effects of some antibiotics on glutathione reductase from sheep liver.

  Journal of enzyme inhibition and medicinal chemistry 20031201

• A simple and sensitive GC method for determination of N-methylpyrrolidine in cefepime and its preparation.

  Journal of pharmaceutical and biomedical analysis 20031124

• Neutropenia in patients receiving long-term cefepime therapy for osteomyelitis.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20031101

• Cefepime versus cefpirome: the importance of creatinine clearance.

  Anesthesia and analgesia 20031001

• Treatment of febrile neutropenic patients with cancer who require hospitalization: a prospective randomized study comparing imipenem and cefepime.

  Cancer 20030901

• Adsorptive stripping voltammetric determination of cefepime at the mercury electrode in human urine and cerebrospinal fluid, and differential pulse polarographic determination in serum.

  Journal of pharmaceutical sciences 20030901

• Antimicrobial spectrum of activity for meropenem and nine broad spectrum antimicrobials: report from the MYSTIC Program (2002) in North America.

  Diagnostic microbiology and infectious disease 20030901

• Post-exposure effects of cefepime and cefpirome on isogenic Escherichia coli hosts producing SHV-extended-spectrum beta-lactamases.

  Journal of chemotherapy (Florence, Italy) 20030801

• Steady-state plasma and intrapulmonary concentrations of cefepime administered in continuous infusion in critically ill patients with severe nosocomial pneumonia.

  Critical care medicine 20030801

• Antibiotic tissue concentrations revisited in lungs.

  Critical care medicine 20030801

• [Yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--I. Gram-positive bacteria].

  The Japanese journal of antibiotics 20030801

• [Yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--II. Gram-negative bacteria].

  The Japanese journal of antibiotics 20030801

• Serum bactericidal activity of trovafloxacin, in combination with cefepime or amikacin, in healthy volunteers.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701

• Stability of cefepime hydrochloride in AutoDose Infusion System bags.

  The Annals of pharmacotherapy 20030601

• Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients.

  American journal of clinical oncology 20030601

• In vitro activity of gatifloxacin alone and in combination with cefepime, meropenem, piperacillin and gentamicin against multidrug-resistant organisms.

  The Journal of antimicrobial chemotherapy 20030501

• Experimental prediction of the evolution of cefepime resistance from the CMY-2 AmpC beta-lactamase.

  Genetics 20030501

• Neurotoxicity induced by Cefepime in a very old hemodialysis patient.

  Clinical nephrology 20030501

• Role of pharmacodynamics in designing dosage regimens for beta-lactams.

  Connecticut medicine 20030501

• Is there a rationale for the continuous infusion of cefepime? A multidisciplinary approach.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030501

• Determination of the dissociation constants of the cephalosporins cefepime and cefpirome using UV spectrometry and pH potentiometry.

  Journal of pharmaceutical and biomedical analysis 20030410

• Enterobacter cloacae ventriculitis successfully treated with cefepime and gentamicin: case report and review of the literature.

  Pharmacotherapy 20030401

• Experimental prediction of the natural evolution of antibiotic resistance.

  Genetics 20030401

• Antibiotic prophylaxis in elective thoracic surgery: cefuroxime versus cefepime.

  The Thoracic and cardiovascular surgeon 20030401

• [Evaluation of a E-test method to detect bactericidy of beta lactam-aminoglycoside associations against Pseudomonas aeruginosa isolates from cystic fibrosis].

  Pathologie-biologie 20030401

• Diffusion of cefepime into cancellous and cortical bone tissue.

  Journal of chemotherapy (Florence, Italy) 20030401

• [Cefepime-amikacin combination in febrile neutropenic children with malignant hemopathy or tumor].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20030401

• [Meningitis caused by multiresistant E. coli after an echo-directed transrectal biopsy].

  Actas urologicas espanolas 20030401

• Cefepime tissue penetration in experimental acute pancreatitis.

  Pancreas 20030301

• Stability and compatibility study of cefepime in comparison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory treatment of cystic fibrosis patients and to administration in intensive care units.

  The Journal of antimicrobial chemotherapy 20030301

• Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa.

  Pharmacotherapy 20030301

• Disposition of cefepime in the central nervous system of patients with external ventricular drains.

  Pharmacotherapy 20030301

• Retrospective review of neurotoxicity induced by cefepime and ceftazidime.

  Pharmacotherapy 20030301

• Cefepime use in a pediatric intensive care unit reduces colonization with resistant bacilli.

  The Pediatric infectious disease journal 20030201

• Pancreatic concentrations of cefepime in experimental necrotizing pancreatitis.

  Journal of chemotherapy (Florence, Italy) 20030201

• A comparison of antibiotic regimens in the treatment of acute melioidosis in a mouse model.

  The Journal of antimicrobial chemotherapy 20030101

• Sustained activity and spectrum of selected extended-spectrum beta-lactams (carbapenems and cefepime) against Enterobacter spp. and ESBL-producing Klebsiella spp.: report from the SENTRY antimicrobial surveillance program (USA, 1997-2000).

  International journal of antimicrobial agents 20030101

• Determination of the frequency of inadequate antibiotic therapy using calculation of indication failure (IF), cumulative indication failure (CIF), and balanced indication failure (BIF).

  Wiener medizinische Wochenschrift (1946) 20030101

• [Comparative clinical and epidemiological evaluation of beta-lactam antibiotics in the treatment of intraabdominal infections].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• Lack of efflux mechanism in a clinical isolate of Pseudomonas aeruginosa highly resistant to beta-lactams and imipenem.

  Folia microbiologica 20030101

• [Cefepime: the new option of target antibiotic therapy].

  Przeglad lekarski 20030101

• [The present and the future of cefepime, a 4th generation cephalosporin].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• [Comparative in vitro activity of cefepime and other antibiotics against clinical strains of gram-negative bacteria].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• [Experience with maxipime in neurosurgical clinic].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• [Cefepime treatment efficacy in surgical patients].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• [Cefepime (maxipime) in the treatment of severe urinary tract infection].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• [Cefepime/amikacin in the empirical antibacterial therapy for patients with hemoblastosis of different forms].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• [Empirical cefepime monotherapy in febrile neutropenia].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• [Cefepime in the treatment of hospital-acquired pneumonia].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• Intraperitoneal infusion allows therapeutic plasma levels of cefepime.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20030101

• Cefepime: a review of its use in the management of hospitalized patients with pneumonia.

  American journal of respiratory medicine : drugs, devices, and other interventions 20030101

• [Activity of fourth generation cephalosporins against clinical isolates of Enterobacteriaceae].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101

• Cefepime or carbapenem treatment for febrile neutropenia as a single agent is as effective as a combination of 4th-generation cephalosporin + aminoglycosides: comparative study.

  American journal of hematology 20021201

• Continuous infusion versus intermittent administration of cefepime in patients with Gram-negative bacilli bacteraemia.

  The Journal of pharmacy and pharmacology 20021201

• Clinical and bacteriological results from the administration of Cefepime (Maxipime) in patients with severe sepsis.

  Medical science monitor : international medical journal of experimental and clinical research 20021101

• Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.

  Oral microbiology and immunology 20021001

• A multicenter comparative study of cefepime versus broad-spectrum antibacterial therapy in moderate and severe bacterial infections.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20021001

• Pharmacodynamics of cefepime in patients with Gram-negative infections.

  The Journal of antimicrobial chemotherapy 20020901

• The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization.

  Bone marrow transplantation 20020901

• Cefepime, piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin alone and in combination against Pseudomonas aeruginosa.

  Diagnostic microbiology and infectious disease 20020901

• Safety and efficacy of cefepime versus ceftazidime in the treatment of severe infections.

  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20020901

• Surgical antibiotic prophylaxis in a Turkish university hospital.

  Journal of chemotherapy (Florence, Italy) 20020801

• Cefepime plus amikacin versus piperacillin-tazobactam plus amikacin for initial antibiotic therapy in haematology patients with febrile neutropenia: results of an open, randomized, multicentre trial.

  The Journal of antimicrobial chemotherapy 20020701

• Geographic variations in activity of broad-spectrum beta-lactams against Pseudomonas aeruginosa: summary of the worldwide SENTRY Antimicrobial Surveillance Program (1997-2000).

  Diagnostic microbiology and infectious disease 20020701

• Emerging antimicrobial resistances among Proteus mirabilis in Europe: report from the MYSTIC Program (1997-2001). Meropenem Yearly Susceptibility Test Information Collection.

  Journal of chemotherapy (Florence, Italy) 20020601

• Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region.

  The Biochemical journal 20020501

• Cefepime MIC as a predictor of the extended-spectrum beta-lactamase type in Klebsiella pneumoniae, Taiwan.

  Emerging infectious diseases 20020501

• Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: risk factors for colonization and impact of antimicrobial formulary interventions on colonization prevalence.

  Infection control and hospital epidemiology 20020501

• Penetration of meropenem and cefepim into pancreatic tissue during the course of experimental acute pancreatitis.

  Pancreas 20020401

• Klebsiella pneumoniae brain abscess in a Taiwanese adult.

  The Journal of infection 20020401

• Pharmacodynamic considerations in the treatment of moderate to severe pseudomonal infections with cefepime.

  The Journal of antimicrobial chemotherapy 20020301

• Cefepime versus ceftazidime as empiric monotherapy for fever and neutropenia in children with cancer.

  The Pediatric infectious disease journal 20020301

• Cefepime is efficacious against penicillin- and quinolone-resistant pneumococci in experimental meningitis.

  The Journal of antimicrobial chemotherapy 20020201

• Nonconvulsive status epilepticus in dialysis patients.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020201

• Cefepime-induced neurotoxicity: an underestimated complication of antibiotherapy in patients with acute renal failure.

  Intensive care medicine 20020201

• A randomized monocentric trial in febrile neutropenic patients: ceftriaxone and gentamicin vs cefepime and gentamicin.

  Annals of hematology 20020101

• Clinical evaluation of the Vitek automated system with cards GNS 122 and 127 and VTK-R07.01 software for antimicrobial susceptibility testing of Pseudomonas aeruginosa.

  Diagnostic microbiology and infectious disease 20020101

• Intravitreal penetration of cefepime after systemic administration to humans.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20020101

• Stability of cefepime dihydrochloride monohydrate in solid state.

  Acta poloniae pharmaceutica 20020101

• Cefepime monotherapy as an empirical initial treatment of patients with febrile neutropenia.

  Medical oncology (Northwood, London, England) 20020101

• [Cefepime (Maxipime) treatment efficacy in surgical patients ].

  Chirurgia (Bucharest, Romania : 1990) 20020101

• Severe neurotoxicity of cefepime in uremic patients.

  Annals of internal medicine 20011204

• [Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].

  Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20011201

• The effectiveness of systemic antibiotics in preventing postoperative, intraabdominal adhesions in an animal model.

  The Journal of surgical research 20011101

• Susceptibility of pseudomonas aeruginosa to cefepime versus ceftazidime in patients with cystic fibrosis.

  Pharmacotherapy 20011101

• Effect of inoculum size on the antibacterial activity of cefpirome and cefepime against Klebsiella pneumoniae strains producing SHV extended-spectrum beta-lactamases.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20011101

• Invasive pulmonary aspergillosis in a puerperant with drug-induced agranulocytosis.

  Internal medicine (Tokyo, Japan) 20011101

• Cefepime versus cefotaxime for empirical treatment of bacterial pneumonia in HIV-infected patients: an open, randomized trial.

  The Journal of antimicrobial chemotherapy 20011001

• Application of the IDSA guidelines for the use of antimicrobial agents in neutropenic patients: impact on reducing the use of glycopeptides.

  Infection control and hospital epidemiology 20011001

• [Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains].

  The Japanese journal of antibiotics 20010901

• Cefepime in vitro activity against derepressed extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Enterobacter cloacae by a disc diffusion method.

  The Journal of antimicrobial chemotherapy 20010801

• Nonconvulsive status epilepticus associated with cephalosporins in patients with renal failure.

  The American journal of medicine 20010801

• Comparative in vitro antimicrobial activity of a new carbapenem, E1010, and tentative disc diffusion test interpretative criteria.

  The Journal of antimicrobial chemotherapy 20010701

• Cefepime versus vancomycin plus netilmicin therapy for continuous ambulatory peritoneal dialysis-associated peritonitis.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20010701

• Effect of cyclosporine, a P-glycoprotein inhibitor, on the pharmacokinetics of cefepime in rat blood and brain: a microdialysis study.

  Life sciences 20010601

• Comparison of cefepime pharmacokinetics in neonatal foals and adult dogs.

  Journal of veterinary pharmacology and therapeutics 20010601

• Cost-effectiveness of cefepime + netilmicin or ceftazidime + amikacin or meropenem monotherapy in febrile neutropenic children with malignancy in Turkey.

  Journal of chemotherapy (Florence, Italy) 20010601

• Efficacy of cefepime versus ceftazidime in the treatment of adult pneumonia.

  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20010601

• Abiotrophia bacteremia in a patient with neutropenic fever and antimicrobial susceptibility testing of Abiotrophia isolates.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010515

• Efficacy of gatifloxacin alone and in combination with cefepime against penicillin-resistant Streptococcus pneumoniae in a rabbit meningitis model and in vitro.

  The Journal of antimicrobial chemotherapy 20010501

• Pancreatic concentrations of cefepime.

  The Journal of antimicrobial chemotherapy 20010501

• Efficiency of cefepime in postoperative meningitis attributable to Enterobacter aerogenes.

  The Journal of trauma 20010501

• High-performance liquid chromatographic determination of cefepime in human plasma and in urine and dialysis fluid using a column-switching technique.

  Journal of chromatography. B, Biomedical sciences and applications 20010425

• Determination and pharmacokinetic study of unbound cefepime in rat bile by liquid chromatography with on-line microdialysis.

  Journal of chromatography. A 20010420

• Randomized comparison of cefepime versus ceftazidime monotherapy for fever and neutropenia in children with solid tumors.

  Medical and pediatric oncology 20010401

• Prediction of gram-negative bacteremia in patients with cancer and febrile neutropenia by means of interleukin-8 levels in serum: targeting empirical monotherapy versus combination therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010301

• Cefepime microbiologic profile and update.

  The Pediatric infectious disease journal 20010301

• Review of the pharmacokinetics of cefepime in children.

  The Pediatric infectious disease journal 20010301

• Empiric use of cefepime in the treatment of lower respiratory tract infections in children.

  The Pediatric infectious disease journal 20010301

• Empiric use of cefepime in the treatment of serious urinary tract infections in children.

  The Pediatric infectious disease journal 20010301

• Cefepime in the empiric treatment of meningitis in children.

  The Pediatric infectious disease journal 20010301

• Comparative study of cefepime versus ceftazidime in the empiric treatment of pediatric cancer patients with fever and neutropenia.

  The Pediatric infectious disease journal 20010301

• Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate.

  FEMS microbiology letters 20010220

• Multicentre study of the in vitro activity of cefepime, a broad-spectrum cephalosporin, compared to other broad-spectrum agents.

  Pathology 20010201

• [Activity of cefepime compared with other antibiotics against major hospital bacterial pathogens].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010201

• [Combination effect of arbekacin and cefepime on mixed culture of MRSA and P. aeruginosa].

  The Japanese journal of antibiotics 20010201

• Neuropsychiatric symptoms during cefepime treatment.

  Pharmacy world & science : PWS 20010201

• Successful use of recombinant tissue plasminogen activator in a patient with relapsing peritonitis.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20010101

• In vitro synergy between cefepime and vancomycin against methicillin-susceptible and -resistant Staphylococcus aureus and Staphylococcus epidermidis.

  The Journal of antimicrobial chemotherapy 20010101

• Ocular penetration of cefepime following systemic administration in humans.

  Ophthalmic surgery and lasers 20010101

• Comparative activities of isepamicin, amikacin, cefepime, and ciprofloxacin alone or in combination with other antibiotics against Stenotrophomonas maltophilia.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20010101

• Pharmacokinetic population study to describe cefepime lung concentrations.

  Pulmonary pharmacology & therapeutics 20010101

• Treatment of febrile neutropenia with cefepime monotherapy.

  Chemotherapy 20010101

• The effects of cefephim, G-CSF, and sucralfate on bacterial translocation in experimentally induced acute pancreatitis.

  Surgery today 20010101

• Activity of cefepime, cefotaxime, ceftazidime, and aztreonam against extended-spectrum-producing isolates of Klebsiella pneumoniae and Escherichia coli from Chilean hospitals.

  Diagnostic microbiology and infectious disease 20010101

• [Cefepime (maxipime) in the treatment of abdominal surgical infections].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

• Effects of cefepime and meropenem on the gastrointestinal colonization of surgical patients by Candida albicans.

  Chemotherapy 20010101

• Comparison of cefepime versus ceftriaxone-amikacin as empirical regimens for the treatment of febrile neutropenia in acute leukemia patients.

  Chemotherapy 20010101

• Comparison of cefepime and ceftazidime in combination with amikacin in the empirical treatment of high-risk patients with febrile neutropenia: a prospective, randomized, multicenter study.

  Scandinavian journal of infectious diseases 20010101

• [A fourth generation cephalosporin--cefepime (maxipime) in pediatrics].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

• [Cefepime (maxipine) in treating abdominal surgical infections].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

• [Use of maxipime in treating infections in neutropenic patients].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

• [Experience in using the fourth generation cephalosporin cefepime (maxipime) in treating Russian patients with severe infections].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

• Susceptibility of bacterial isolates to cefepime in comparison to other broad spectrum antimicrobial agents at a tertiary care center in Lebanon.

  Le Journal medical libanais. The Lebanese medical journal 20010101

• [Cefepime (maxipime), large spectrum 4th generation cephalosporin, resistant to beta-lactamases].

  Chirurgia (Bucharest, Romania : 1990) 20010101

• beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.

  The Journal of biological chemistry 20000121

• Synergistic antimycobacterial activity between ethambutol and the beta-lactam drug cefepime.

  Diagnostic microbiology and infectious disease 19970701

• beta-Lactamase activity in mycobacteria including Mycobacterium avium and suppression of their growth by a beta-lactamase-stable antibiotic.

  Microbios 19950101

• Efficacy of cefepime in a Staphylococcus aureus endocarditis rat model.

  The Journal of antimicrobial chemotherapy 19931101