1234356-69-4 | Derazantinib

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$76.00	$54.00
5mg	95%	in stock	$82.00	$57.00
10mg	95%	in stock	$132.00	$92.00
25mg	95%	in stock	$225.00	$157.00
50mg	95%	in stock	$360.00	$252.00

Description

• Catalog Number: AA26449
• Chemical Name: Derazantinib
• CAS Number: 1234356-69-4
• Molecular Formula: C29H29FN4O
• Molecular Weight: 468.56516319999986
• MDL Number: MFCD30532770
• SMILES: COCCNCCc1cccc(c1)Nc1ncc2c(-c3ccccc3[C@@H](C2)c2ccccc2F)n1

Computed Properties

• Complexity: 638
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 35
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 9
• XLogP3: 5.3

Literature

• A Phase 1 study of ARQ 087, an oral pan-FGFR inhibitor in patients with advanced solid tumours.

  British journal of cancer 20171121

• Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation.

  PloS one 20160101