1236699-92-5 | AS-703026

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$16.00	$11.00
5mg	98%	in stock	$22.00	$15.00
10mg	98%	in stock	$29.00	$20.00
50mg	98%	in stock	$65.00	$45.00
250mg	98%	in stock	$183.00	$128.00
5g	98%	in stock	$2,018.00	$1,412.00

Description

• Catalog Number: AA26920
• Chemical Name: AS-703026
• CAS Number: 1236699-92-5
• Molecular Formula: C15H15FIN3O3
• Molecular Weight: 431.2008
• MDL Number: MFCD16660676
• SMILES: OC[C@H](CNC(=O)c1ccncc1Nc1ccc(cc1F)I)O

Computed Properties

• Complexity: 391
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 6
• XLogP3: 1.7

Literature

• MEK inhibitors as a chemotherapeutic intervention in multiple myeloma.

  Blood cancer journal 20130301

• MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy.

  Cancer research 20110115

• Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo.

  British journal of haematology 20100501