1257849-07-2 | Fmoc-5-chloro-l-tryptophan

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$15.00	$11.00
250mg	98%	in stock	$36.00	$26.00
1g	98%	in stock	$124.00	$87.00
5g	98%	in stock	$567.00	$397.00

Description

• Catalog Number: AA31823
• Chemical Name: Fmoc-5-chloro-l-tryptophan
• CAS Number: 1257849-07-2
• Molecular Formula: C26H21ClN2O4
• Molecular Weight: 460.9089
• MDL Number: MFCD16883066
• SMILES: O=C(N[C@H](C(=O)O)Cc1c[nH]c2c1cc(Cl)cc2)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 698
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 33
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 7
• XLogP3: 5.4

Upstream Synthesis Route

Fmoc-5-chloro-L-tryptophan is a valuable building block in chemical synthesis, particularly in the field of peptide synthesis. With its unique structure incorporating the chlorine atom at the 5-position of the tryptophan moiety, this compound offers a specialized functionality that can be strategically utilized in the creation of complex peptide structures. In peptide synthesis, Fmoc-5-chloro-L-tryptophan plays a crucial role as a key intermediate in the construction of peptide chains. Its incorporation into the peptide sequence enables the introduction of specific structural and chemical properties, thereby influencing the overall characteristics and behavior of the resulting peptide. The presence of the chloro substituent provides opportunities for selective modifications and interactions, allowing for the fine-tuning of peptide structures for various applications.Additionally, the Fmoc protection group attached to the amino terminus of 5-chloro-L-tryptophan facilitates its compatibility with solid-phase peptide synthesis techniques. This enables efficient and controlled assembly of peptides on solid supports, ensuring high purity and yield in the synthesis process. Moreover, the Fmoc protection strategy allows for sequential deprotection and coupling steps, leading to the synthesis of longer and more complex peptide sequences with precision.Overall, Fmoc-5-chloro-L-tryptophan serves as a versatile and valuable tool in chemical synthesis, particularly in the realm of peptide chemistry where tailored peptide structures are desired for applications in drug discovery, biochemical research, and beyond.