1264-62-6 | Erythromycin, 2'-(ethyl butanedioate)

Packsize	Purity	Availability	Price	Discounted Price
1g	98%(HPLC)	in stock	$47.00	$33.00
5g	98%(HPLC)	in stock	$111.00	$78.00
25g	98%(HPLC)	in stock	$431.00	$302.00

Description

• Catalog Number: AA37053
• Chemical Name: Erythromycin, 2'-(ethyl butanedioate)
• CAS Number: 1264-62-6
• Molecular Formula: C43H75NO16
• Molecular Weight: 862.0527
• MDL Number: MFCD00084692
• SMILES: CCOC(=O)CCC(=O)OC1C(OC(CC1N(C)C)C)OC1C(C)C(OC2OC(C)C(C(C2)(C)OC)O)C(C)C(=O)OC(CC)C(C(C(C(=O)C(CC1(C)O)C)C)O)(C)O
• NSC Number: 756758

Computed Properties

• Complexity: 1450
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 18
• Heavy Atom Count: 60
• Hydrogen Bond Acceptor Count: 17
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 14
• XLogP3: 3.4

Literature

• Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.

  Toxicology and applied pharmacology 20170301

• Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.

  PloS one 20140101

• Effects of curcumin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen, in rats: possible role of CYP3A4 and P-glycoprotein inhibition by curcumin.

  Die Pharmazie 20120201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications.

  Journal of separation science 20100501

• Comparison of the effect of azithromycin versus erythromycin on antroduodenal pressure profiles of patients with chronic functional gastrointestinal pain and gastroparesis.

  Digestive diseases and sciences 20100301

• [Specific ototoxic effects of monomycin in immature animals].

  Vestnik otorinolaringologii 20090101

• Pharmacokinetics of erythromycin after the administration of intravenous and various oral dosage forms to dogs.

  Journal of veterinary pharmacology and therapeutics 20081201

• Multiple aphthoid syphilitic chancres of the oral cavity.

  International journal of STD & AIDS 20080701

• Familial cases presenting very early onset autosomal dominant Alzheimer's disease with I143T in presenilin-1 gene: implication for genotype-phenotype correlation.

  Neurogenetics 20080201

• SCN5A R1193Q polymorphism associated with progressive cardiac conduction defects and long QT syndrome in a Chinese family.

  Journal of medical genetics 20080201

• [Erythromycin ethylsuccinate obtaining possibilities].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

• Femtosecond IR spectroscopy of peroxycarbonate photodecomposition: S1-lifetime determines decarboxylation rate.

  The journal of physical chemistry. A 20071011

• Mechanism for the degradation of erythromycin A and erythromycin A 2'-ethyl succinate in acidic aqueous solution.

  The journal of physical chemistry. A 20071011

• Antibiotics for whooping cough (pertussis).

  The Cochrane database of systematic reviews 20070718

• Nondestructive quantitative analysis of erythromycin ethylsuccinate powder drug via short-wave near-infrared spectroscopy combined with radial basis function neural networks.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070701

• Construction of universal quantitative models for determination of roxithromycin and erythromycin ethylsuccinate in tablets from different manufacturers using near infrared reflectance spectroscopy.

  Journal of pharmaceutical and biomedical analysis 20060503

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Simultaneous determination of erythromycin ethylsuccinate and its metabolite erythromycin in human plasma using liquid chromatography-electrospray ionization mass spectrometry for clinical study.

  Journal of pharmaceutical and biomedical analysis 20060224

• A validated spectrofluorometric assay for the determination of certain macrolide antibiotics in pharmaceutical formulations and spiked biological fluids.

  Journal of AOAC International 20060101

• Antibiotics for whooping cough (pertussis).

  The Cochrane database of systematic reviews 20050125

• Pharmacokinetics of erythromycin ethylsuccinate after intragastric administration to healthy foals.

  Veterinary therapeutics : research in applied veterinary medicine 20020101

• Open-Label, parallel-group, multicenter, randomized study of cefprozil versus erythromycin in children with group A streptococcal pharyngitis/tonsillitis.

  Clinical therapeutics 20011101

• Synergistic anti-Pneumocystis carinii effects of erythromycin and sulfisoxazole.

  Journal of acquired immune deficiency syndromes 19910101

• Prolonged cholestasis and disappearance of interlobular bile ducts following chlorpropamide and erythromycin ethylsuccinate. Case of drug interaction?

  Liver 19881201