127-47-9 | Vitamin A Acetate

Packsize	Purity	Availability	Price	Discounted Price
100mg	2800000 IU/g	in stock	$6.00	$4.00
5g	2800000	in stock	$24.00	$17.00
25g	2800000 IU/g	in stock	$27.00	$19.00
500g	2800000	in stock	$467.00	$327.00

Description

• Catalog Number: AA41951
• Chemical Name: Vitamin A Acetate
• CAS Number: 127-47-9
• Molecular Formula: C22H32O2
• Molecular Weight: 328.4883
• MDL Number: MFCD00019413
• SMILES: CC(=O)OC/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C

Computed Properties

• Complexity: 596
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 4
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• XLogP3: 6.3

Literature

• Hepatic Detoxification of Bisphenol A is Retinoid-Dependent.

  Toxicological sciences : an official journal of the Society of Toxicology 20170501

• Retinoids modulate thioacetamide-induced acute hepatotoxicity.

  Toxicological sciences : an official journal of the Society of Toxicology 20140601

• Lemon (Citrus limon, Burm.f.) essential oil enhances the trans-epidermal release of lipid-(A, E) and water-(B6, C) soluble vitamins from topical emulsions in reconstructed human epidermis.

  International journal of cosmetic science 20120801

• Nanoscale domains with nematic order in supercooled vitamin-A acetate: molecular dynamics studies.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20110501

• Retinyl acetate-loaded nanoparticles: dermal penetration and release of the retinyl acetate.

  International journal of pharmaceutics 20110214

• Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system.

  Microbial cell factories 20110101

• Development and validation of a dissolution test method for vitamin A in dietary supplement tablets.

  Journal of pharmaceutical and biomedical analysis 20101102

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• A randomized controlled trial to assess the impact of dietary energy sources, feed supplements, and the presence of super-shedders on the detection of Escherichia coli O157:H7 in feedlot cattle using different diagnostic procedures.

  Foodborne pathogens and disease 20100901

• An optimized and validated RP-HPLC/UV detection method for simultaneous determination of all-trans-retinol (vitamin A) and alpha-tocopherol (vitamin E) in human serum: comparison of different particulate reversed-phase HPLC columns.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100901

• Vitamin A is systemically bioavailable after intratracheal administration with surfactant in an animal model of newborn respiratory distress.

  Pediatric research 20100601

• Small quantities of carotenoid-rich tropical green leafy vegetables indigenous to Africa maintain vitamin A status in Mongolian gerbils ( Meriones unguiculatus).

  The British journal of nutrition 20100601

• Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis.

  Nature 20100415

• Cosmeceuticals: the evidence behind the retinoids.

  Aesthetic surgery journal 20100101

• Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance.

  Investigative ophthalmology & visual science 20091001

• Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/- mice.

  Investigative ophthalmology & visual science 20090901

• Preparation, in vitro and in vivo evaluation of solid-state self-nanoemulsifying drug delivery system (SNEDDS) of vitamin A acetate.

  Journal of drug targeting 20090701

• Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.

  Human molecular genetics 20090615

• Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

  The Journal of biological chemistry 20090529

• Plasma turnover of 3,4-didehydroretinol (vitamin A2) increases in vitamin A-deficient rats fed low versus high dietary fat.

  Journal of lipid research 20090401

• Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands.

  Analytical biochemistry 20090115

• Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice.

  Investigative ophthalmology & visual science 20090101

• Simultaneous determination of benzophenone-3, retinol and retinyl acetate in pig ear skin layers by high-performance liquid chromatography.

  Biomedical chromatography : BMC 20081001

• New type of microfabricated carbon electrodes for high-performance liquid chromatography--amperometric detection of fat-soluble vitamins and antioxidants.

  Journal of chromatography. A 20080711

• Simultaneous determination of five fat-soluble vitamins in feed by high-performance liquid chromatography following solid-phase extraction.

  Journal of chromatographic science 20080401

• [Effect of vitamin A provision on antineoplastic resistance in rats].

  Voprosy pitaniia 20080101

• Chemotherapeutic/chemopreventive role of retinoids in chemically induced skin carcinogenesis in albino mice.

  International journal of dermatology 20071101

• Interactions of human serum albumin with retinoic acid, retinal and retinyl acetate.

  Biochemical pharmacology 20070315

• Novel retinoid targets in the mouse limb during organogenesis.

  Toxicological sciences : an official journal of the Society of Toxicology 20061101

• Casting a broad network: fishing for mechanisms of retinoid teratogenicity.

  Toxicological sciences : an official journal of the Society of Toxicology 20061101

• Simultaneous analysis of Vitamins A and E in infant milk-based formulae by normal-phase high-performance liquid chromatography-diode array detection using a short narrow-bore column.

  Journal of chromatography. A 20060728

• Alterations in gene expression in rat skin exposed to 56Fe ions and dietary vitamin A acetate.

  Radiation research 20060501

• Retinoid receptor antagonists alter the pattern of apoptosis in organogenesis stage mouse limbs.

  Toxicological sciences : an official journal of the Society of Toxicology 20060301

• [Effect of allogenic intracranial transplantation of embryonal neural cell-precursors on the humoral immune response to neurospecific proteins in rabbits].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101

• Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.

  PLoS medicine 20051101

• Dietary levels of all-trans retinol affect retinoid nuclear receptor expression and skeletal development in European sea bass larvae.

  The British journal of nutrition 20050601

• Extra-hepatic vitamin A concentrations in captive Rhesus (Macaca mulatta) and Marmoset (Callithrix jacchus) monkeys fed excess vitamin A.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050301

• Dehydration reaction of hydroxenin monoacetate in carbon tetrachloride and an aliphatic alcohol under ultrasound irradiation.

  Ultrasonics sonochemistry 20050101

• The analysis of the zero-order and the second derivative spectra of retinol acetate, tocopherol acetate and coenzyme Q10 and estimation of their analytical usefulness for their simultaneous determination in synthetic mixtures and pharmaceuticals.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040801

• Transport across liquid membranes containing vitamin A (retinol acetate).

  Journal of colloid and interface science 20040315

• Tumouricidal activity of gilthead seabream (Sparus aurata L.) natural cytotoxic cells: the role played in vitro and in vivo by retinol acetate.

  Fish & shellfish immunology 20030201

• [Immunomodulating effect of short-term deep local cooling and its enhancement with vitamin A].

  Patologicheskaia fiziologiia i eksperimental'naia terapiia 20030101

• Articular cartilage degradation and de-differentiation of chondrocytes by the systemic administration of retinyl acetate-ectopic production of osteoblast stimulating factor-1 by chondrocytes in mice.

  Osteoarthritis and cartilage 20021201

• The action of a dietary retinoid on gene expression and cancer induction in electron-irradiated rat skin.

  Journal of radiation research 20021201

• Changes in some innate defence parameters of seabream (Sparus aurata L.) induced by retinol acetate.

  Fish & shellfish immunology 20021001

• Dual isotope test for assessing beta-carotene cleavage to vitamin A in humans.

  European journal of nutrition 20020801

• Production of lipospheres as carriers for bioactive compounds.

  Biomaterials 20020601

• Increased antibody production by retinoids is related to the fusion partner of human hybridomas.

  Bioscience, biotechnology, and biochemistry 20020101

• Hydrogen peroxide-induced inhibition of vasomotor activity: evaluation of single and combined treatments with vitamin A and insulin in streptozotocin-diabetic rats.

  International journal of experimental diabetes research 20020101

• Prevention of neonatal estrogen imprinting by vitamin A as indicated by estrogen receptor expression in the mouse vagina.

  Cell and tissue research 20011201

• Impaired vitamin A-mediated mucosal IgA response in IL-5 receptor-knockout mice.

  Biochemical and biophysical research communications 20010713

• Determination of retinoids in human serum, tocopherol and retinyl acetate in pharmaceuticals by RP-LC with electrochemical detection.

  Journal of pharmaceutical and biomedical analysis 20010701

• The effects of some antioxidant vitamin- and trace element-supplemented diets on activities of SOD, CAT, GSH-Px and LPO levels in chicken tissues.

  Cell biochemistry and function 20010601

• On-line supercritical fluid extraction/enzymatic hydrolysis of vitamin a esters: a new simplified approach for the determination of vitamins a and e in food.

  Journal of agricultural and food chemistry 20010201

• Fibroma induction in rat skin following single or multiple doses of 1.0 GeV/nucleon 56Fe ions from the Brookhaven Alternating Gradient Synchrotron (AGS).

  Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 20010101

• Budd-Chiari syndrome likely related to a slimming drug preparation.

  Journal of hepatology 19951101

• Co-carcinogenic effect of retinyl acetate on forestomach carcinogenesis of male F344 rats induced with butylated hydroxyanisole.

  Japanese journal of cancer research : Gann 19880301

• Effects of BHA, d-alpha-tocopherol and retinol acetate on TCDD-mediated changes in lipid peroxidation, glutathione peroxidase activity and survival.

  Xenobiotica; the fate of foreign compounds in biological systems 19840701

• Virucidal activity of retinal.

  Antimicrobial agents and chemotherapy 19790901

• Retinyl acetate prophylaxis in cancer of the urinary bladder.

  Investigative urology 19790301