127559-33-5 | Boc-D-Serinol(bzl)

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$31.00	$22.00
250mg	97%	in stock	$45.00	$32.00
1g	97%	in stock	$111.00	$78.00
5g	97%	in stock	$427.00	$299.00

Description

• Catalog Number: AA42751
• Chemical Name: Boc-D-Serinol(bzl)
• CAS Number: 127559-33-5
• Molecular Formula: C15H23NO4
• Molecular Weight: 281.3474
• MDL Number: MFCD00235944
• SMILES: OC[C@@H](NC(=O)OC(C)(C)C)COCc1ccccc1

Computed Properties

• Complexity: 282
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 1.7

Upstream Synthesis Route

The upstream synthesis route for Boc-D-Serinol(benzyl) is as follows:

1. Start with D-serine as the chiral starting material. Protect the amino group by reacting D-serine with di-tert-butyl dicarbonate (Boc2O) under basic conditions, such as sodium bicarbonate (NaHCO3) in an organic solvent like dichloromethane, to obtain Boc-D-serine.

2. Protect the carboxyl group of Boc-D-serine by converting it to a benzyl ester. This can be achieved through an esterification reaction with benzyl alcohol in the presence of a catalyst like DMAP (4-dimethylaminopyridine) and a condensing agent like DCC (dicyclohexylcarbodiimide). The target molecule, Boc-D-serinol(bzl), is thereby obtained.

3. Purification steps, such as column chromatography, should be carried out to achieve the desired purity of the Boc-D-Serinol(bzl).

It is critical that the stereochemistry of the starting D-serine is maintained throughout the synthesis to obtain the correct enantiomer of Boc-D-Serinol(bzl).