127625-29-0 | 2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide

Packsize	Purity	Availability	Price	Discounted Price
1mg		1 week	$106.00	$74.00
5mg		1 week	$163.00	$114.00
10mg		1 week	$209.00	$146.00
25mg		1 week	$309.00	$216.00
50mg		1 week	$431.00	$302.00
100mg		1 week	$616.00	$431.00
500mg		1 week	$1,315.00	$920.00

Description

• Catalog Number: AA42865
• Chemical Name: 2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide
• CAS Number: 127625-29-0
• Molecular Formula: C23H24FN3O2S
• Molecular Weight: 425.5190
• MDL Number: MFCD00866648
• SMILES: Fc1ccc(cc1)N1CCN(CC1)CCCN1c2cccc3c2c(S1(=O)=O)ccc3

Computed Properties

• Complexity: 683
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 30
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• XLogP3: 4

Literature

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  Archives of toxicology 20171201

• Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.

  Journal of medicinal chemistry 20090723

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  Journal of pharmaceutical sciences 20081101

• Molecular mobility in glass forming fananserine: a dielectric, NMR, and TMDSC investigation.

  Pharmaceutical research 20060401

• N-[(3S)-1-benzylpyrrolidin-3-yl]-(2-thienyl)benzamides: human dopamine D4 ligands with high affinity for the 5-HT2A receptor.

  Bioorganic & medicinal chemistry letters 20051201

• [Thermodynamics of drug polymorphism: domains and stability hierarchy by pressure temperature diagram. Application to the tetramorphism of fananserine].

  Annales pharmaceutiques francaises 20020501

• 4-(Phenylsulfonyl)piperidines: novel, selective, and bioavailable 5-HT(2A) receptor antagonists.

  Journal of medicinal chemistry 20020117

• Current and novel approaches to the drug treatment of schizophrenia.

  Journal of medicinal chemistry 20010215

• Autoradiographic studies of RP 62203, a potent 5-HT2 receptor antagonist. Pharmacological characterization of [3H]RP 62203 binding in the rat brain.

  European journal of pharmacology 19930316