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Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways.
Toxicology and applied pharmacology 20180915
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Synergistic action of the nephrotoxic mycotoxins ochratoxin A and citrinin at nanomolar concentrations in human proximal tubule-derived cells.
Toxicology letters 20180701
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ROS generation and MAPKs activation contribute to the Ni-induced testosterone synthesis disturbance in rat Leydig cells.
Toxicology letters 20180615
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Acrylamide-induced oxidative stress and inflammatory response are alleviated by N-acetylcysteine in PC12 cells: Involvement of the crosstalk between Nrf2 and NF-κB pathways regulated by MAPKs.
Toxicology letters 20180515
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Exposure to DBP and High Iodine Aggravates Autoimmune Thyroid Disease Through Increasing the Levels of IL-17 and Thyroid-Binding Globulin in Wistar Rats.
Toxicological sciences : an official journal of the Society of Toxicology 20180501
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Expression of optineurin isolated from rat-injured dental pulp and the effects on inflammatory signals in normal rat kidney cells.
Odontology 20180401
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Calpain and JNK pathways participate in isoflurane - induced nucleus translocation of apoptosis-inducing factor in the brain of neonatal rats.
Toxicology letters 20180315
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t-BuOOH induces ferroptosis in human and murine cell lines.
Archives of toxicology 20180201
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Polyhexamethylene guanidine phosphate induces IL-6 and TNF-α expression through JNK-dependent pathway in human lung epithelial cells.
The Journal of toxicological sciences 20180101
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Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells.
Toxicology 20171201
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β-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways.
Environmental toxicology 20171101
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Colistin-induced autophagy and apoptosis involves the JNK-Bcl2-Bax signaling pathway and JNK-p53-ROS positive feedback loop in PC-12 cells.
Chemico-biological interactions 20171101
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Polysaccharide purified from Ganoderma atrum induced activation and maturation of murine myeloid-derived dendritic cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20171001
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Bisphenol A disrupts steroidogenesis and induces a sex hormone imbalance through c-Jun phosphorylation in Leydig cells.
Chemosphere 20171001
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Varenicline promotes endothelial cell migration by lowering vascular endothelial-cadherin levels via the activated α7 nicotinic acetylcholine receptor-mitogen activated protein kinase axis.
Toxicology 20170901
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Nimbolide induces apoptosis in human nasopharyngeal cancer cells.
Environmental toxicology 20170801
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Editor's Highlight: Farnesoid X Receptor Protects Against Low-Dose Carbon Tetrachloride-Induced Liver Injury Through the Taurocholate-JNK Pathway.
Toxicological sciences : an official journal of the Society of Toxicology 20170801
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Leptin induces CREB-dependent aromatase activation through COX-2 expression in breast cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170801
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Andrographolide reduced VEGFA expression in hepatoma cancer cells by inactivating HIF-1α: The involvement of JNK and MTA1/HDCA.
Chemico-biological interactions 20170801
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Sinigrin attenuates the progression of atherosclerosis in ApoE(-/-) mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression.
Chemico-biological interactions 20170625
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Amyloid β induces NLRP3 inflammasome activation in retinal pigment epithelial cells via NADPH oxidase- and mitochondria-dependent ROS production.
Journal of biochemical and molecular toxicology 20170601
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The flame retardant 2,2',4,4'-Tetrabromodiphenyl ether enhances the expression of corticotropin-releasing hormone in the placental cell model JEG-3.
Chemosphere 20170501
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Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer.
Environmental toxicology 20170401
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Dysregulation of MAP Kinase Signaling Pathways Including p38MAPK, SAPK/JNK, and ERK1/2 in Cultured Rat Cerebellar Astrocytes Exposed to Diphenylarsinic Acid.
Toxicological sciences : an official journal of the Society of Toxicology 20170401
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Vibrio cholerae Cholix Toxin-Induced HepG2 Cell Death is Enhanced by Tumor Necrosis Factor-Alpha Through ROS and Intracellular Signal-Regulated Kinases.
Toxicological sciences : an official journal of the Society of Toxicology 20170401
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Inhibition of NF-κB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38.
Environmental toxicology 20170201
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mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.
Environmental toxicology 20170101
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Salvianolic Acid A Protects H9c2 Cells from Arsenic Trioxide-Induced Injury via Inhibition of the MAPK Signaling Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20170101
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Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells.
Chemico-biological interactions 20161225
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Aflatoxin B1 disrupts transient receptor potential channel activity and increases COX-2 expression in JEG-3 placental cells.
Chemico-biological interactions 20161225
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Atg5-dependent autophagy plays a protective role against methylmercury-induced cytotoxicity.
Toxicology letters 20161116
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Neogambogic acid prevents silica-induced fibrosis via inhibition of high-mobility group box 1 and MCP-1-induced protein 1.
Toxicology and applied pharmacology 20161015
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Air pollution-related metals induce differential cytokine responses in bronchial epithelial cells.
Toxicology in vitro : an international journal published in association with BIBRA 20161001
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Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2.
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2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells.
Archives of toxicology 20160901
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Allopurinol induces innate immune responses through mitogen-activated protein kinase signaling pathways in HL-60 cells.
Journal of applied toxicology : JAT 20160901
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The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3β-dependent threonine-286 phosphorylation in human colorectal cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160901
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Hexachlorobenzene modulates the crosstalk between the aryl hydrocarbon receptor and transforming growth factor-β1 signaling, enhancing human breast cancer cell migration and invasion.
Toxicology 20160729
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Arsenic trioxide mediates HAPI microglia inflammatory response and subsequent neuron apoptosis through p38/JNK MAPK/STAT3 pathway.
Toxicology and applied pharmacology 20160715
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Benzo(a)pyrene inhibits migration and invasion of extravillous trophoblast HTR-8/SVneo cells via activation of the ERK and JNK pathway.
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Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Toxicology 20160701
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MCPIP1 Regulates Alveolar Macrophage Apoptosis and Pulmonary Fibroblast Activation After in vitro Exposure to Silica.
Toxicological sciences : an official journal of the Society of Toxicology 20160501
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Serine 574 phosphorylation alters transcriptional programming of FOXO3 by selectively enhancing apoptotic gene expression.
Cell death and differentiation 20160401
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Hydroquinone stimulates cell invasion through activator protein-1-dependent induction of MMP-9 in HepG2 human hepatoma cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160301
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Arecoline-induced pro-fibrotic proteins in LLC-PK1 cells are dependent on c-Jun N-terminal kinase.
Toxicology 20160217
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Calcium Contributes to the Cytotoxic Interaction Between Diclofenac and Cytokines.
Toxicological sciences : an official journal of the Society of Toxicology 20160201
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Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis.
Chemical research in toxicology 20160119
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The Role of MAPK Pathways in Airborne Fine Particulate Matter-Induced Upregulation of Endothelin Receptors in Rat Basilar Arteries.
Toxicological sciences : an official journal of the Society of Toxicology 20160101
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The role of HO-1 in protection against lead-induced neurotoxicity.
Neurotoxicology 20160101
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DJ-1 mutation decreases astroglial release of inflammatory mediators.
Neurotoxicology 20160101
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Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells.
PloS one 20160101
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Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells.
Toxicology 20151202
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Involvement of mitogen-activated protein kinase and NF-κB signaling pathways in perfluorooctane sulfonic acid-induced inflammatory reaction in BV2 microglial cells.
Journal of applied toxicology : JAT 20151201
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Induction of HO-1 by carbon monoxide releasing molecule-2 attenuates thrombin-induced COX-2 expression and hypertrophy in primary human cardiomyocytes.
Toxicology and applied pharmacology 20151201
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CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings.
Toxicology and applied pharmacology 20151201
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Endosulfan induces COX-2 expression via NADPH oxidase and the ROS, MAPK, and Akt pathways.
Archives of toxicology 20151101
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Low-dose Bisphenol A Activates Cyp11a1 Gene Expression and Corticosterone Secretion in Adrenal Gland via the JNK Signaling Pathway.
Toxicological sciences : an official journal of the Society of Toxicology 20151101
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Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.
Oncotarget 20151020
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Role of human pulmonary fibroblast-derived MCP-1 in cell activation and migration in experimental silicosis.
Toxicology and applied pharmacology 20151015
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Integrated Transcriptional and Proteomic Analysis of Growth Hormone Suppression Mediated by Trichothecene T-2 Toxin in Rat GH3 Cells.
Toxicological sciences : an official journal of the Society of Toxicology 20151001
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Coordinated regulation of Nrf2 and histone H3 serine 10 phosphorylation in arsenite-activated transcription of the human heme oxygenase-1 gene.
Biochimica et biophysica acta 20151001
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Quercetin protects mouse liver against CCl₄-induced inflammation by the TLR2/4 and MAPK/NF-κB pathway.
International immunopharmacology 20150901
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Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.
Chemical research in toxicology 20150817
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Formoterol synergy with des-ciclesonide inhibits IL-4 expression in IgE/antigen-induced mast cells by inhibiting JNK activation.
European journal of pharmacology 20150815
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The involvement of p62-Keap1-Nrf2 antioxidative signaling pathway and JNK in the protection of natural flavonoid quercetin against hepatotoxicity.
Free radical biology & medicine 20150801
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Resveratrol Enhances Chemosensitivity in Mouse Melanoma Model Through Connexin 43 Upregulation.
Environmental toxicology 20150708
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FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells.
Toxicology letters 20150702
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Reactive oxygen species-dependent JNK downregulated olaquindox-induced autophagy in HepG2 cells.
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Reactive oxygen species and c-Jun N-terminal kinases contribute to TEMPO-induced apoptosis in L5178Y cells.
Chemico-biological interactions 20150625
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Quercetin promotes the osteogenic differentiation of rat mesenchymal stem cells via mitogen-activated protein kinase signaling.
Experimental and therapeutic medicine 20150601
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Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.
Chemical research in toxicology 20150518
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The c-Jun N-terminal kinase signaling pathway mediates chrysotile asbestos-induced alveolar epithelial cell apoptosis.
Molecular medicine reports 20150501
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MAPK and NF-κB pathways are involved in bisphenol A-induced TNF-α and IL-6 production in BV2 microglial cells.
Inflammation 20150401
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Transcriptional upregulation centra of HO-1 by EGB via the MAPKs/Nrf2 pathway in mouse C2C12 myoblasts.
Toxicology in vitro : an international journal published in association with BIBRA 20150301
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Resveratrol induces apoptosis of human chronic myelogenous leukemia cells in vitro through p38 and JNK-regulated H2AX phosphorylation.
Acta pharmacologica Sinica 20150301
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Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function.
Toxicology and applied pharmacology 20150215
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JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.
Toxicology 20150203
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Activation of MAPK pathways and downstream transcription factors in 2-aminobiphenyl-induced apoptosis.
Environmental toxicology 20150201
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JNK implication in adipocyte-like cell death induced by chemotherapeutic drug cisplatin.
The Journal of toxicological sciences 20150201
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Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Oncotarget 20150201
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Acrylamide Induces Senescence in Macrophages through a Process Involving ATF3, ROS, p38/JNK, and a Telomerase-Independent Pathway.
Chemical research in toxicology 20150120
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Carnosic acid protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson's disease: involvement of antioxidative enzymes induction.
Chemico-biological interactions 20150105
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The role of mitogen-activated protein kinase in cadmium-induced primary rat cerebral cortical neurons apoptosis via a mitochondrial apoptotic pathway.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20150101
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Resveratrol reduces prostaglandin E1-stimulated osteoprotegerin synthesis in osteoblasts: suppression of stress-activated protein kinase/c-Jun N-terminal kinase.
Prostaglandins & other lipid mediators 20150101
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Fulvic acid attenuates homocysteine-induced cyclooxygenase-2 expression in human monocytes.
BMC complementary and alternative medicine 20150101
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The Green Tea Component (-)-Epigallocatechin-3-Gallate Sensitizes Primary Endothelial Cells to Arsenite-Induced Apoptosis by Decreasing c-Jun N-Terminal Kinase-Mediated Catalase Activity.
PloS one 20150101
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Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K.
EMBO molecular medicine 20141201
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Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2.
International journal of oncology 20141201
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Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.
Molecular carcinogenesis 20141101
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The role of autophagy in usnic acid-induced toxicity in hepatic cells.
Toxicological sciences : an official journal of the Society of Toxicology 20141101
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Regulation by resveratrol of prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts.
International journal of molecular medicine 20141101
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Induction of GADD45α protects M17 neuroblastoma cells against MPP*.
IUBMB life 20141101
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Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells.
Toxicology letters 20141015
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Abrus precatorius agglutinin-derived peptides induce ROS-dependent mitochondrial apoptosis through JNK and Akt/P38/P53 pathways in HeLa cells.
Chemico-biological interactions 20141005
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Overexpression of human E46K mutant α-synuclein impairs macroautophagy via inactivation of JNK1-Bcl-2 pathway.
Molecular neurobiology 20141001
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Down-regulation by resveratrol of basic fibroblast growth factor-stimulated osteoprotegerin synthesis through suppression of Akt in osteoblasts.
International journal of molecular sciences 20141001
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Suppression by resveratrol of prostaglandin D2-stimulated osteoprotegerin synthesis in osteoblasts.
Prostaglandins, leukotrienes, and essential fatty acids 20140901
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Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47(phox) pathway.
Toxicology and applied pharmacology 20140901
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BNIP3 upregulation by ERK and JNK mediates cadmium-induced necrosis in neuronal cells.
Toxicological sciences : an official journal of the Society of Toxicology 20140801
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Regulation of human CYP2C9 expression by electrophilic stress involves activator protein 1 activation and DNA looping.
Molecular pharmacology 20140801
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Generation and characterization of gsuα:EGFP transgenic zebrafish for evaluating endocrine-disrupting effects.
Toxicology and applied pharmacology 20140701
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Preferential expression of PAPPA in human preadipocytes from omental fat.
The Journal of endocrinology 20140701
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Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways.
Oncology reports 20140701
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Molecular mechanisms of cadmium-induced fibroblast growth factor 23 upregulation in osteoblast-like cells.
Toxicological sciences : an official journal of the Society of Toxicology 20140601
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Withaferin A is an inhibitor of endothelial protein C receptor shedding in vitro and in vivo.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140601
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Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells.
International journal of molecular medicine 20140601
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Carcinogenic metalloid arsenic induces expression of mdig oncogene through JNK and STAT3 activation.
Cancer letters 20140501
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Trovafloxacin potentiation of lipopolysaccharide-induced tumor necrosis factor release from RAW 264.7 cells requires extracellular signal-regulated kinase and c-Jun N-Terminal Kinase.
The Journal of pharmacology and experimental therapeutics 20140501
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Cadmium induces PC12 cells apoptosis via an extracellular signal-regulated kinase and c-Jun N-terminal kinase-mediated mitochondrial apoptotic pathway.
Biological trace element research 20140501
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Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pathway.
Cancer science 20140501
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Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation.
Chemico-biological interactions 20140325
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Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product.
Toxicology and applied pharmacology 20140301
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Exploring the effects of tert-butylhydroperoxide induced liver injury using proteomic approach.
Toxicology 20140227
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Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid.
Free radical biology & medicine 20140201
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The role of thioredoxin-1 in suppression of endoplasmic reticulum stress in Parkinson disease.
Free radical biology & medicine 20140201
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Humic acid in drinking well water induces inflammation through reactive oxygen species generation and activation of nuclear factor-κB/activator protein-1 signaling pathways: a possible role in atherosclerosis.
Toxicology and applied pharmacology 20140115
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Autophagy blockade sensitizes the anticancer activity of CA-4 via JNK-Bcl-2 pathway.
Toxicology and applied pharmacology 20140115
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Resveratrol suppresses prostaglandin F(2α)-induced osteoprotegerin synthesis in osteoblasts: inhibition of the MAP kinase signaling.
Archives of biochemistry and biophysics 20140115
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Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways.
Toxicology letters 20140103
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Evaluation and mechanistic analysis of the cytotoxicity of the acyl glucuronide of nonsteroidal anti-inflammatory drugs.
Drug metabolism and disposition: the biological fate of chemicals 20140101
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Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.
Journal of neurochemistry 20140101
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CDK5-induced p-PPARγ(Ser 112) downregulates GFAP via PPREs in developing rat brain: effect of metal mixture and troglitazone in astrocytes.
Cell death & disease 20140101
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Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling.
Nature communications 20140101
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Cytoprotective effect of kaempferol on paraquat-exposed BEAS-2B cells via modulating expression of MUC5AC.
Biological & pharmaceutical bulletin 20140101
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FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20140101
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Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells.
Immunobiology 20131201
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Hyperosmolarity-induced up-regulation of claudin-4 mediated by NADPH oxidase-dependent H2O2 production and Sp1/c-Jun cooperation.
Biochimica et biophysica acta 20131201
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Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway.
Toxicology and applied pharmacology 20131115
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Calcineurin inhibitors recruit protein kinases JAK2 and JNK, TLR signaling and the UPR to activate NF-κB-mediated inflammatory responses in kidney tubular cells.
Toxicology and applied pharmacology 20131101
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ONTD induces apoptosis of human hepatoma Bel-7402 cells via a MAPK-dependent mitochondrial pathway and the depletion of intracellular glutathione.
The international journal of biochemistry & cell biology 20131101
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NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells.
Toxicology and applied pharmacology 20131015
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The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard.
Toxicology and applied pharmacology 20131015
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Arsenic induces the expressions of angiogenesis-related factors through PI3K and MAPK pathways in SV-HUC-1 human uroepithelial cells.
Toxicology letters 20131009
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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces microglial nitric oxide production and subsequent rat primary cortical neuron apoptosis through p38/JNK MAPK pathway.
Toxicology 20131004
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Immunostimulatory activity of polysaccharides from Cheonggukjang.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901
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Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130801
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Inhibitory effect of resveratrol dimerized derivatives on nitric oxide production in lipopolysaccharide-induced RAW 264.7 cells.
Bioorganic & medicinal chemistry letters 20130801
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MCM-2 is a therapeutic target of Trichostatin A in colon cancer cells.
Toxicology letters 20130731
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Apoptosis induced by trimethyltin chloride in human neuroblastoma cells SY5Y is regulated by a balance and cross-talk between NF-κB and MAPKs signaling pathways.
Archives of toxicology 20130701
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Galangin attenuates mast cell-mediated allergic inflammation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130701
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Arsenic upregulates the expression of angiotensin II Type I receptor in mouse aortic endothelial cells.
Toxicology letters 20130620
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Cajaninstilbene acid (CSA) exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway.
Toxicology letters 20130607
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Sodium fluoride induces apoptosis in odontoblasts via a JNK-dependent mechanism.
Toxicology 20130607
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Oxidative stress and MAPK involved into ATF2 expression in immortalized human urothelial cells treated by arsenic.
Archives of toxicology 20130601
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Interaction of inflammatory and anti-inflammatory responses in microglia by Staphylococcus aureus-derived lipoteichoic acid.
Toxicology and applied pharmacology 20130515
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Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway.
The Journal of biological chemistry 20130510
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A novel antitubulin agent, DPQZ, induces cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.
Archives of toxicology 20130501
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Valproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activity.
Glia 20130501
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JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis.
Toxicology letters 20130426
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A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
The Biochemical journal 20130415
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Titanium dioxide nanoparticles increase inflammatory responses in vascular endothelial cells.
Toxicology 20130405
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Retinoic acid influences the embryoid body formation in mouse embryonic stem cells by induction of caspase and p38 MAPK/JNK-mediated apoptosis.
Environmental toxicology 20130401
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Induction of apoptotic death and retardation of neuronal differentiation of human neural stem cells by sodium arsenite treatment.
Experimental cell research 20130401
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Sodium arsenite induces cyclooxygenase-2 expression in human uroepithelial cells through MAPK pathway activation and reactive oxygen species induction.
Toxicology in vitro : an international journal published in association with BIBRA 20130401
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β-Ionone attenuates LPS-induced pro-inflammatory mediators such as NO, PGE2 and TNF-α in BV2 microglial cells via suppression of the NF-κB and MAPK pathway.
Toxicology in vitro : an international journal published in association with BIBRA 20130301
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Butein protects human dental pulp cells from hydrogen peroxide-induced oxidative toxicity via Nrf2 pathway-dependent heme oxygenase-1 expressions.
Toxicology in vitro : an international journal published in association with BIBRA 20130301
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TNF-α-mediated NF-κB survival signaling impairment by cisplatin enhances JNK activation allowing synergistic apoptosis of renal proximal tubular cells.
Biochemical pharmacology 20130115
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Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals.
Toxicology 20130107
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Exposure to the JNK inhibitor SP600125 (anthrapyrazolone) during early zebrafish development results in morphological defects.
Journal of applied toxicology : JAT 20130101
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Ethyl pyruvate protects rats from phosgene-induced pulmonary edema by inhibiting cyclooxygenase2 and inducible nitric oxide synthase expression.
Journal of applied toxicology : JAT 20130101
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JNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenic.
Cell cycle (Georgetown, Tex.) 20130101
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The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells.
PloS one 20130101
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A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors.
PloS one 20130101
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Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation.
PloS one 20130101
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The antimetastatic effects of resveratrol on hepatocellular carcinoma through the downregulation of a metastasis-associated protease by SP-1 modulation.
PloS one 20130101
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Oxidative stress and mitogen-activated protein kinase pathways involved in cadmium-induced BRL 3A cell apoptosis.
Oxidative medicine and cellular longevity 20130101
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GATA-2 transduces LPS-induced il-1β gene expression in macrophages via a toll-like receptor 4/MD88/MAPK-dependent mechanism.
PloS one 20130101
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JNK and NADPH oxidase involved in fluoride-induced oxidative stress in BV-2 microglia cells.
Mediators of inflammation 20130101
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Bisphenol-A impairs insulin action and up-regulates inflammatory pathways in human subcutaneous adipocytes and 3T3-L1 cells.
PloS one 20130101
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Gsta4 Null Mouse Embryonic Fibroblasts Exhibit Enhanced Sensitivity to Oxidants: Role of 4-Hydroxynonenal in Oxidant Toxicity.
Open journal of apoptosis 20130101
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High glucose-induced increased expression of endothelin-1 in human endothelial cells is mediated by activated CCAAT/enhancer-binding proteins.
PloS one 20130101
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Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 20121215
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JNK pathway decreases thyroid hormones via TRH receptor: a novel mechanism for disturbance of thyroid hormone homeostasis by PCB153.
Toxicology 20121208
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Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice.
Diabetes 20121201
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Apoptosis of K562 leukemia cells by Abnobaviscum F®, a European mistletoe extract.
Oncology reports 20121201
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Quercetin up-regulates LDL receptor expression in HepG2 cells.
Phytotherapy research : PTR 20121101
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Apoptosis signal-regulating kinase 1 is mediated in TNF-α-induced CCL2 expression in human synovial fibroblasts.
Journal of cellular biochemistry 20121101
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Fullerene derivative prevents cellular transformation induced by JAK2 V617F mutant through inhibiting c-Jun N-terminal kinase pathway.
Cellular signalling 20121101
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Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expression.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121101
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Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes.
Journal of lipid research 20121101
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Opposed arsenite-mediated regulation of p53-survivin is involved in neoplastic transformation, DNA damage, or apoptosis in human keratinocytes.
Toxicology 20121028
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Diallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc.
European journal of nutrition 20121001
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Distinct functions of JNK and c-Jun in oxidant-induced hepatocyte death.
Journal of cellular biochemistry 20121001
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JNK-dependent Stat3 phosphorylation contributes to Akt activation in response to arsenic exposure.
Toxicological sciences : an official journal of the Society of Toxicology 20121001
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Protective role of quercetin against lead-induced inflammatory response in rat kidney through the ROS-mediated MAPKs and NF-κB pathway.
Biochimica et biophysica acta 20121001
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Mitogen-activated protein kinases-dependent induction of hepatocyte growth factor production in human dermal fibroblasts by the antibiotic polymyxin B.
Cytokine 20121001
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Transcriptional and translational regulation of COX-2 expression by cadmium in C6 glioma cells.
International journal of molecular medicine 20121001
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Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways.
European journal of pharmacology 20120905
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Protective role of metabolism by intestinal microflora in butyl paraben-induced toxicity in HepG2 cell cultures.
Toxicology letters 20120903
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Preliminary evidence for the dedifferentiation of RAW 264.7 cells into mesenchymal progenitor-like cells by a purine analog.
Tissue engineering. Part A 20120901
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Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
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Sargachromanol G regulates the expression of osteoclastogenic factors in human osteoblast-like MG-63 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
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The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment.
Molecular cancer research : MCR 20120901
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Pimaric acid from Aralia cordata has an inhibitory effect on TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1.
Chemico-biological interactions 20120830
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PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120801
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Inhibitory effect of Styrax Japonica Siebold et al. Zuccarini glycoprotein (38 kDa) on interleukin-1β and induction proteins in chromium(VI)-treated BNL CL.2 cells.
Molecular and cellular biochemistry 20120801
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Tumor necrosis factor alpha stimulates cathepsin K and V activity via juxtacrine monocyte-endothelial cell signaling and JNK activation.
Molecular and cellular biochemistry 20120801
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Suppression of adhesion molecule expression by phenanthrene-containing extract of bulbils of Chinese Yam in vascular smooth muscle cells through inhibition of MAPK, Akt and NF-κB.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801
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Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
Journal of neurochemistry 20120801
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Inhibition of c-Jun N-terminal kinase prevents blood-brain barrier disruption and normalizes the expression of tight junction proteins clautin-5 and ZO-1 in a rat model of subarachnoid hemorrhage.
Acta neurochirurgica 20120801
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cAMP-dependent proteolysis of GATA-6 is linked to JNK-signaling pathway.
Biochemical and biophysical research communications 20120713
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Prodigiosin-induced cytotoxicity involves RAD51 down-regulation through the JNK and p38 MAPK pathways in human breast carcinoma cell lines.
Toxicology letters 20120707
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Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c-Jun N-terminal kinase, SP600125 and BI-78D3.
British journal of pharmacology 20120701
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Monocyte chemoattractant protein-1 mediates angiotensin II-induced vascular smooth muscle cell proliferation via SAPK/JNK and ERK1/2.
Molecular and cellular biochemistry 20120701
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The effects of ginsenoside Rb1 on JNK in oxidative injury in cardiomyocytes.
Archives of pharmacal research 20120701
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Evaluation of sirtuin role in neuroprotection of retinal ganglion cells in hypoxia.
Investigative ophthalmology & visual science 20120628
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Delayed inhibition of c-Jun N-terminal kinase worsens outcomes after focal cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20120613
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Sphingosine-1-phosphate is a mediator of TNF-α action on the Na+/K+ ATPase in HepG2 cells.
Journal of cellular biochemistry 20120601
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Cross-talk between receptor tyrosine kinase and tumor necrosis factor-α signaling networks regulates apoptosis but not proliferation.
Molecular & cellular proteomics : MCP 20120601
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Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601
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Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.
Archives of toxicology 20120601
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Tumor necrosis factor-α and interleukin-1β expression pathway induced by Streptococcus mutans in macrophage cell line RAW 264.7.
Molecular oral microbiology 20120601
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[The protective effects of inhibition of c-Jun N-terminal kinase signal pathway on the intestinal barrier in rats with endotoxemia].
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20120601
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Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation.
The Journal of biological chemistry 20120518
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Arecoline-induced death of human leukemia K562 cells is associated with surface up-modulation of TNFR2.
Journal of cellular physiology 20120501
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Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells.
Microvascular research 20120501
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Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice.
Pharmacology, biochemistry, and behavior 20120501
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Intraperitoneal injection of JNK-specific inhibitor SP600125 inhibits the expression of presenilin-1 and Notch signaling in mouse brain without induction of apoptosis.
Brain research 20120411
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Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1α via epidermal growth factor receptor-mediated signaling pathways.
Journal of applied toxicology : JAT 20120401
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Enhanced phosphorylation of MAPKs by NE promotes TNF-α production by macrophage through α adrenergic receptor.
Inflammation 20120401
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IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells.
Inflammation 20120401
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Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice.
Phytotherapy research : PTR 20120401
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Effects of c-Jun N-terminal kinase signaling pathway on severe acute pancreatitis-associated lung injury.
Pancreas 20120401
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High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol.
The international journal of biochemistry & cell biology 20120401
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Daunorubicin induces cell death via activation of apoptotic signalling pathway and inactivation of survival pathway in muscle-derived stem cells.
Cell biology and toxicology 20120401
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Dynamics and regulation of lipid droplet formation in lipopolysaccharide (LPS)-stimulated microglia.
Biochimica et biophysica acta 20120401
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Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line.
Chemical research in toxicology 20120319
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Ginsenoside Rh1 suppresses matrix metalloproteinase-1 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathway in human hepatocellular carcinoma cells.
European journal of pharmacology 20120315
-
Inhibition of JNK/dFOXO pathway and caspases rescues neurological impairments in Drosophila Alzheimer's disease model.
Biochemical and biophysical research communications 20120302
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Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway.
Molecular and cellular biochemistry 20120301
-
Zinc oxide nanoparticles-induced intercellular adhesion molecule 1 expression requires Rac1/Cdc42, mixed lineage kinase 3, and c-Jun N-terminal kinase activation in endothelial cells.
Toxicological sciences : an official journal of the Society of Toxicology 20120301
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Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms.
Carcinogenesis 20120301
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Nicotine stimulates urokinase-type plasminogen activator receptor expression and cell invasiveness through mitogen-activated protein kinase and reactive oxygen species signaling in ECV304 endothelial cells.
Toxicology and applied pharmacology 20120301
-
P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
Free radical research 20120301
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Fructose-1,6-bisphosphate attenuates induction of nitric oxide synthase in microglia stimulated with lipopolysaccharide.
Life sciences 20120227
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Involvement of oxidative stress-induced ERK/JNK activation in the Cu(2+)/pyrrolidine dithiocarbamate complex-triggered mitochondria-regulated apoptosis in pancreatic β-cells.
Toxicology letters 20120205
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Effect of donor JNK signal transduction inhibition on transplant outcome in brain dead rat model.
Inflammation 20120201
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Quercetin supplementation suppresses the secretion of pro-inflammatory cytokines in the lungs of Mongolian gerbils and in A549 cells exposed to benzo[a]pyrene alone or in combination with β-carotene: in vivo and ex vivo studies.
The Journal of nutritional biochemistry 20120201
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Genistein inhibit cytokines or growth factor-induced proliferation and transformation phenotype in fibroblast-like synoviocytes of rheumatoid arthritis.
Inflammation 20120201
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Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases.
American journal of physiology. Cell physiology 20120201
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Heme oxygenase-1 mediates the protective role of quercetin against ethanol-induced rat hepatocytes oxidative damage.
Toxicology in vitro : an international journal published in association with BIBRA 20120201
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Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation.
International journal of oncology 20120201
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Exploring the function of the JNK (c-Jun N-terminal kinase) signalling pathway in physiological and pathological processes to design novel therapeutic strategies.
Biochemical Society transactions 20120201
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SNP-induced apoptosis may be mediated with caspase inhibitor by JNK signaling pathways in rabbit articular chondrocytes.
The Journal of toxicological sciences 20120201
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[Effect of expression of c-jun N-terminal kinase on neuron autophagy following diffuse brain injury in rats].
Zhonghua wai ke za zhi [Chinese journal of surgery] 20120201
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Smad7 acts as a negative regulator of the epidermal growth factor (EGF) signaling pathway in breast cancer cells.
Cancer letters 20120128
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Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 20120115
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A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.
Toxicology and applied pharmacology 20120115
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c-Jun N-terminal kinase 2 phosphorylates endothelial nitric oxide synthase at serine 116 and regulates nitric oxide production.
Biochemical and biophysical research communications 20120106
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Human foetal intestinal fibroblasts are hyper-responsive to lipopolysaccharide stimulation.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120101
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Involvement of JNK and NF-κB pathways in lipopolysaccharide (LPS)-induced BAG3 expression in human monocytic cells.
Experimental cell research 20120101
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The dysregulation of the monocyte/macrophage effector function induced by isopropanol is mediated by the defective activation of distinct members of the AP-1 family of transcription factors.
Toxicological sciences : an official journal of the Society of Toxicology 20120101
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Function of MAPK and downstream transcription factors in monomer-induced apoptosis.
Biomaterials 20120101
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The saturated fatty acid palmitate induces human monocytic cell toxicity toward neuronal cells: exploring a possible link between obesity-related metabolic impairments and neuroinflammation.
Journal of Alzheimer's disease : JAD 20120101
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Mutual regulation of growth hormone and bone morphogenetic protein system in steroidogenesis by rat granulosa cells.
Endocrinology 20120101
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SP600125 inhibits Orthopoxviruses replication in a JNK1/2 -independent manner: Implication as a potential antipoxviral.
Antiviral research 20120101
-
GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.
PloS one 20120101
-
miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene.
PloS one 20120101
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Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway.
Neuro-degenerative diseases 20120101
-
Activation of JNK signaling mediates connective tissue growth factor expression and scar formation in corneal wound healing.
PloS one 20120101
-
Effects of dihydropyridine calcium channel blockers on oxidized low-density lipoprotein induced proliferation and oxidative stress of vascular smooth muscle cells.
BMC research notes 20120101
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High-mobility group box 1 protein is implicated in advanced glycation end products-induced vascular endothelial growth factor A production in the rat retinal ganglion cell line RGC-5.
Molecular vision 20120101
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MEKK1-MKK4-JNK-AP1 pathway negatively regulates Rgs4 expression in colonic smooth muscle cells.
PloS one 20120101
-
Curcumin enhances cytotoxic effects of bortezomib in human multiple myeloma H929 cells: potential roles of NF-κB/JNK.
International journal of molecular sciences 20120101
-
Neuregulin promotes incomplete autophagy of prostate cancer cells that is independent of mTOR pathway inhibition.
PloS one 20120101
-
Camel milk triggers apoptotic signaling pathways in human hepatoma HepG2 and breast cancer MCF7 cell lines through transcriptional mechanism.
Journal of biomedicine & biotechnology 20120101
-
Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
-
Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells.
The Journal of toxicological sciences 20120101
-
Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer.
PloS one 20120101
-
[Effects of several inhibitors of intracellular signaling on production of cytokines and signal proteins in RAW 264.7 cells cultivated with low dose ammonium].
Biofizika 20120101
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Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes.
PloS one 20120101
-
Mda-9/syntenin promotes human brain glioma migration through focal adhesion kinase (FAK)-JNK and FAK-AKT signaling.
Asian Pacific journal of cancer prevention : APJCP 20120101
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The apoptotic volume decrease is an upstream event of MAP kinase activation during Staurosporine-induced apoptosis in HeLa cells.
International journal of molecular sciences 20120101
-
Stressor-like effects of c-Jun N-terminal kinase (JNK) inhibition.
PloS one 20120101
-
Calcium entry mediates hyperglycemia-induced apoptosis through Ca(2+)/calmodulin-dependent kinase II in retinal capillary endothelial cells.
Molecular vision 20120101
-
Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms.
PloS one 20120101
-
Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells.
Blood cells, molecules & diseases 20111215
-
Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells.
Biochemical and biophysical research communications 20111202
-
Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.
Journal of hepatology 20111201
-
Novel participation of transglutaminase-2 through c-Jun N-terminal kinase activation in sphingosylphosphorylcholine-induced keratin reorganization of PANC-1 cells.
Biochimica et biophysica acta 20111201
-
MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide.
Biochimica et biophysica acta 20111201
-
CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death.
Journal of neurochemistry 20111201
-
MAPK and AP-1 proteins are increased in term pre-labour fetal membranes overlying the cervix: regulation of enzymes involved in the degradation of fetal membranes.
Placenta 20111201
-
JNK inhibitors increase osteogenesis in Nf1-deficient cells.
Bone 20111201
-
Novel stably transfected gene reporter human hepatoma cell line for assessment of aryl hydrocarbon receptor transcriptional activity: construction and characterization.
Environmental science & technology 20111201
-
Porphyromonas endodontalis lipopolysaccharides induce RANKL by mouse osteoblast in a way different from that of Escherichia coli lipopolysaccharide.
Journal of endodontics 20111201
-
Thymus peptides regulate activity of RAW 264.7 macrophage cells: inhibitory analysis and a role of signal cascades.
Expert opinion on therapeutic targets 20111201
-
Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing anticancer prodrugs.
Journal of medicinal chemistry 20111124
-
Ellipticine induces apoptosis in human endometrial cancer cells: the potential involvement of reactive oxygen species and mitogen-activated protein kinases.
Toxicology 20111118
-
Nickel(II) induced JNK activation-regulated mitochondria-dependent apoptotic pathway leading to cultured rat pancreatic β-cell death.
Toxicology 20111118
-
Antimetastatic effect and mechanism of ovatodiolide in MDA-MB-231 human breast cancer cells.
Chemico-biological interactions 20111115
-
Lung injury caused by high tidal volume mechanical ventilation and hyperoxia is dependent on oxidant-mediated c-Jun NH2-terminal kinase activation.
Journal of applied physiology (Bethesda, Md. : 1985) 20111101
-
c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.
Neuroscience research 20111101
-
Thymosin β4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis under serum deprivation.
Journal of cellular physiology 20111101
-
Sodium dl-α-tocopheryl-6-O-phosphate inhibits PGE₂ production in keratinocytes induced by UVB, IL-1β and peroxidants.
Bioorganic & medicinal chemistry 20111101
-
The Ebolavirus VP24 protein blocks phosphorylation of p38 mitogen-activated protein kinase.
The Journal of infectious diseases 20111101
-
FGF-2- and TGF-β1-induced downregulation of lumican and keratocan in activated corneal keratocytes by JNK signaling pathway.
Investigative ophthalmology & visual science 20111101
-
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Nature biotechnology 20111101
-
Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.
The Journal of biological chemistry 20111021
-
Levodopa activates apoptosis signaling kinase 1 (ASK1) and promotes apoptosis in a neuronal model: implications for the treatment of Parkinson's disease.
Chemical research in toxicology 20111017
-
Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite.
Toxicology letters 20111010
-
Carmustine induces ERK- and JNK-dependent cell death of neuronally-differentiated PC12 cells via generation of reactive oxygen species.
Toxicology in vitro : an international journal published in association with BIBRA 20111001
-
Apolipoprotein D mediates autocrine protection of astrocytes and controls their reactivity level, contributing to the functional maintenance of paraquat-challenged dopaminergic systems.
Glia 20111001
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Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells.
Biochimica et biophysica acta 20111001
-
JNK inhibition by SP600125 attenuates trans-10, cis-12 conjugated linoleic acid-mediated regulation of inflammatory and lipogenic gene expression.
Lipids 20111001
-
Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways.
Anticancer research 20111001
-
Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.
Journal of medicinal chemistry 20110922
-
Activation of non-canonical Wnt/JNK pathway by Wnt3a is associated with differentiation fate determination of human bone marrow stromal (mesenchymal) stem cells.
Biochemical and biophysical research communications 20110916
-
Angiotensin II type 1 receptor signalling regulates microRNA differentially in cardiac fibroblasts and myocytes.
British journal of pharmacology 20110901
-
Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.
Journal of molecular medicine (Berlin, Germany) 20110901
-
tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.
Neurological research 20110901
-
Arsenic increases lipopolysaccharide-dependent expression of interleukin-8 gene by stimulating a redox-sensitive pathway that strengthens p38-kinase activation.
Molecular immunology 20110901
-
Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.
The Journal of biological chemistry 20110819
-
Hepatocyte growth factor induces a proangiogenic phenotype and mobilizes endothelial progenitor cells by activating Nox2.
Antioxidants & redox signaling 20110815
-
Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells.
Chemico-biological interactions 20110815
-
Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis.
Cancer biology & therapy 20110815
-
MAPKs ERK and p38, but not JNK phosphorylation, modulate IL-6 and TNF-α secretion following OK-432 in vitro stimulation of purified human monocytes.
Scandinavian journal of immunology 20110801
-
Increased JNK1 activity contributes to the upregulation of ApoD in the apocrine secretory gland cells from axillary osmidrosis.
Molecular and cellular biochemistry 20110801
-
Critical role of c-Jun N-terminal kinase in regulating bFGF-induced angiogenesis in vitro.
Journal of biochemistry 20110801
-
A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells.
Cancer biology & therapy 20110801
-
P66Shc mediated ferritin degradation--a novel mechanism of ROS formation.
Free radical biology & medicine 20110801
-
Effects of downregulation of aquaporin1 by peptidoglycan and lipopolysaccharide via MAPK pathways in MeT-5A cells.
Lung 20110801
-
The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells.
The Journal of biological chemistry 20110729
-
Increased level of apoptosis in rat brains and SH-SY5Y cells exposed to excessive fluoride--a mechanism connected with activating JNK phosphorylation.
Toxicology letters 20110728
-
SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells.
Stem cells and development 20110701
-
5-aminolevulinic acid induce apoptosis via NF-κB/JNK pathway in human oral cancer Ca9-22 cells.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20110701
-
Dermal fibroblasts influence the expression profile of 14-3-3 proteins in human keratinocytes.
Molecular and cellular biochemistry 20110701
-
ERK is involved in EGF-mediated protection of tight junctions, but not adherens junctions, in acetaldehyde-treated Caco-2 cell monolayers.
American journal of physiology. Gastrointestinal and liver physiology 20110701
-
Protective effects of SP600125 on renal ischemia-reperfusion injury in rats.
The Journal of surgical research 20110701
-
CXCL2 mediates lipopolysaccharide-induced osteoclastogenesis in RANKL-primed precursors.
Cytokine 20110701
-
Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.
Biochimica et biophysica acta 20110701
-
Identification of new inhibitors of protein kinase R guided by statistical modeling.
Bioorganic & medicinal chemistry letters 20110701
-
CPEB1 modulates lipopolysaccharide-mediated iNOS induction in rat primary astrocytes.
Biochemical and biophysical research communications 20110617
-
Phosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradation.
The Biochemical journal 20110615
-
Toll-like receptor 2-mediated sequential activation of MyD88 and MAPKs contributes to lipopolysaccharide-induced sp-a gene expression in human alveolar epithelial cells.
Immunobiology 20110601
-
Roles of mitogen-activated protein kinases in the modulation of endothelial cell function following thermal injury.
Shock (Augusta, Ga.) 20110601
-
Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin.
Experimental neurology 20110601
-
The signalling axis mediating neuronal apoptosis in response to [Pt(O,O'-acac)(γ-acac)(DMS)].
Biochemical pharmacology 20110601
-
Hyperglycemia induces apoptosis of pancreatic islet endothelial cells via reactive nitrogen species-mediated Jun N-terminal kinase activation.
Biochimica et biophysica acta 20110601
-
Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.
Toxicology and applied pharmacology 20110601
-
Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells.
Journal of dermatological science 20110601
-
Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages.
Biochimica et biophysica acta 20110601
-
Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.
Toxicology letters 20110530
-
Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.
The Journal of surgical research 20110515
-
Virtual screening and further development of novel ALK inhibitors.
Bioorganic & medicinal chemistry 20110515
-
Activation of the JNK pathway by nanosecond pulsed electric fields.
Biochemical and biophysical research communications 20110513
-
Cinnamaldehyde enhances Nrf2 nuclear translocation to upregulate phase II detoxifying enzyme expression in HepG2 cells.
Journal of agricultural and food chemistry 20110511
-
Role of JNK/ATF-2 pathway in inhibition of thrombospondin-1 (TSP-1) expression and apoptosis mediated by doxorubicin and camptothecin in FTC-133 cells.
Biochimica et biophysica acta 20110501
-
Regulation of JNK activity in the apoptotic response of intestinal epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 20110501
-
Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticles.
Journal of immunology (Baltimore, Md. : 1950) 20110501
-
c-Jun NH₂-terminal kinase contributes to dexmedetomidine-induced contraction in isolated rat aortic smooth muscle.
Yonsei medical journal 20110501
-
Interference of the apoptotic signaling pathway in RGC stress response by SP600125 in moderate ocular hypertensive rats.
The Chinese journal of physiology 20110430
-
Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice.
Science (New York, N.Y.) 20110415
-
5-Hydroxytryptamine induces cyclooxygenase-2 in rat vascular smooth muscle cells: Mechanisms involving Src, PKC and MAPK activation [corrected].
European journal of pharmacology 20110410
-
p,p'-Dichlorodiphenoxydichloroethylene induced apoptosis of Sertoli cells through oxidative stress-mediated p38 MAPK and mitochondrial pathway.
Toxicology letters 20110410
-
Helicobacter pylori VacA reduces the cellular expression of STAT3 and pro-survival Bcl-2 family proteins, Bcl-2 and Bcl-XL, leading to apoptosis in gastric epithelial cells.
Digestive diseases and sciences 20110401
-
Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase.
Nephron. Physiology 20110401
-
Lithospermic acid B protects β-cells from cytokine-induced apoptosis by alleviating apoptotic pathways and activating anti-apoptotic pathways of Nrf2-HO-1 and Sirt1.
Toxicology and applied pharmacology 20110401
-
Insulin-induced oxidative stress up-regulates heme oxygenase-1 via diverse signaling cascades in the C2 skeletal myoblast cell line.
Endocrinology 20110401
-
Role of c-Jun N-terminal kinase activation in blastema formation during planarian regeneration.
Development, growth & differentiation 20110401
-
Pro-survival effects of JNK and p38 MAPK pathways in LPS-induced activation of BV-2 cells.
Biochemical and biophysical research communications 20110318
-
Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells.
Toxicology and applied pharmacology 20110315
-
Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds.
Bioorganic & medicinal chemistry 20110315
-
Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
European journal of pharmacology 20110311
-
Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.
Archives of toxicology 20110301
-
Preantral follicle growth is regulated by c-Jun-N-terminal kinase (JNK) pathway.
Reproductive sciences (Thousand Oaks, Calif.) 20110301
-
Inhibition of JNK phosphorylation reverses memory deficit induced by β-amyloid (1-42) associated with decrease of apoptotic factors.
Behavioural brain research 20110301
-
Upregulation of RhoB via c-Jun N-terminal kinase signaling induces apoptosis of the human gastric carcinoma NUGC-3 cells treated with NSC12618.
Carcinogenesis 20110301
-
Androgen receptor-mediated regulation of the anti-atherogenic enzyme CYP27A1 involves the JNK/c-jun pathway.
Archives of biochemistry and biophysics 20110215
-
JNK regulates binding of alpha-catenin to adherens junctions and cell-cell adhesion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110201
-
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
Apoptosis : an international journal on programmed cell death 20110201
-
Quercetin induces FasL-related apoptosis, in part, through promotion of histone H3 acetylation in human leukemia HL-60 cells.
Oncology reports 20110201
-
Targeting transcription through inhibition of TBP.
Oncotarget 20110201
-
α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.
British journal of cancer 20110104
-
Mitogen-activated protein kinase inhibitors improve heart function and prevent fibrosis in cardiomyopathy caused by mutation in lamin A/C gene.
Circulation 20110104
-
Fluid shear stress-induced JNK activity leads to actin remodeling for cell alignment.
Journal of cellular physiology 20110101
-
Gefitinib-induced epidermal growth factor receptor-independent keratinocyte apoptosis is mediated by the JNK activation pathway.
The British journal of dermatology 20110101
-
Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.
Toxicology and applied pharmacology 20110101
-
Critical role of the JNK-p53-GADD45α apoptotic cascade in mediating oxidative cytotoxicity in hippocampal neurons.
British journal of pharmacology 20110101
-
Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut.
Molecular and cellular biochemistry 20110101
-
Epimorphin protects hepatocytes from oxidative stress by inhibiting mitochondrial injury.
Journal of gastroenterology and hepatology 20110101
-
The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation.
Cell transplantation 20110101
-
SP600125 inhibits cap-dependent translation independently of the c-Jun N-terminal kinase pathway.
Cell structure and function 20110101
-
[Effect of JNK pathway in apoptosis of PC12 cell by MPP+].
Wei sheng yan jiu = Journal of hygiene research 20110101
-
Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways.
Archives of pharmacal research 20110101
-
Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells.
BMC cancer 20110101
-
Protective effect of a JNK inhibitor against retinal ganglion cell loss induced by acute moderate ocular hypertension.
Molecular vision 20110101
-
Tumor necrosis factor-α enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells.
Journal of biomedical science 20110101
-
Dual specificity phosphatase 1 regulates human inducible nitric oxide synthase expression by p38 MAP kinase.
Mediators of inflammation 20110101
-
CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes.
Arthritis research & therapy 20110101
-
Suppression of MMP-2 attenuates TNF-α induced NF-κB activation and leads to JNK mediated cell death in glioma.
PloS one 20110101
-
Inhibition of c-Jun N-terminal kinase attenuates low shear stress-induced atherogenesis in apolipoprotein E-deficient mice.
Molecular medicine (Cambridge, Mass.) 20110101
-
Vitamin K3 and vitamin C alone or in combination induced apoptosis in leukemia cells by a similar oxidative stress signalling mechanism.
Cancer cell international 20110101
-
Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells.
Journal of neuroinflammation 20110101
-
Resveratrol inhibits Cdk5 activity through regulation of p35 expression.
Molecular pain 20110101
-
Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response.
Journal of biomedical science 20110101
-
Unfertilized Xenopus eggs die by Bad-dependent apoptosis under the control of Cdk1 and JNK.
PloS one 20110101
-
Stretch-inducible expression of connective tissue growth factor (CTGF) in human osteoblasts-like cells is mediated by PI3K-JNK pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
-
Coordinated regulation of ATF2 by miR-26b in γ-irradiated lung cancer cells.
PloS one 20110101
-
c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells.
Journal of translational medicine 20110101
-
Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy.
PloS one 20110101
-
Pyrrolidine dithiocarbamate (PDTC)/Cu complex induces lung epithelial cell apoptosis through mitochondria and ER-stress pathways.
Toxicology letters 20101215
-
Cardiac-specific overexpression of catalase attenuates paraquat-induced myocardial geometric and contractile alteration: role of ER stress.
Free radical biology & medicine 20101215
-
Endoplasmic reticulum stress-mediated apoptosis of EBV-transformed B cells by cross-linking of CD70 is dependent upon generation of reactive oxygen species and activation of p38 MAPK and JNK pathway.
Journal of immunology (Baltimore, Md. : 1950) 20101215
-
Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase.
Cancer research 20101215
-
p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation.
Cell death and differentiation 20101201
-
JNK-mediated transcriptional upregulation of RhoB is critical for apoptosis of HCT-116 colon cancer cells by a novel diarylsulfonylurea derivative.
Apoptosis : an international journal on programmed cell death 20101201
-
Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK.
Toxicology and applied pharmacology 20101115
-
Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells.
Cancer research 20101115
-
Resveratrol enhances NK cell cytotoxicity: possible role for aryl hydrocarbon receptor.
Journal of cellular physiology 20101101
-
DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells.
Cancer letters 20101101
-
Icaritin induces apoptosis of HepG2 cells via the JNK1 signaling pathway independent of the estrogen receptor.
Planta medica 20101101
-
The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy.
Journal of pineal research 20101101
-
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
-
The c-Jun N-terminal kinase inhibitor SP600125 is neuroprotective in amygdala kindled rats.
Brain research 20101021
-
The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells.
Toxicology letters 20101020
-
Enantioselective cytotoxicity of isocarbophos is mediated by oxidative stress-induced JNK activation in human hepatocytes.
Toxicology 20101009
-
3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression.
Toxicology letters 20101005
-
SP600125, a competitive inhibitor of JNK attenuates streptozotocin induced neurocognitive deficit and oxidative stress in rats.
Pharmacology, biochemistry, and behavior 20101001
-
MCP-1 production in temporomandibular joint inflammation.
Journal of dental research 20101001
-
[Simvastatin suppress lipopolysaccharides induced upregulation of lipoprotein associated phospholipase A(2) expression in macrophages via inactivation of p38MAPK pathway].
Zhonghua xin xue guan bing za zhi 20101001
-
The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells.
FEBS letters 20100924
-
Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100901
-
Lipid soluble smoke particles upregulate endothelin receptors in rat basilar artery.
Toxicology letters 20100901
-
Negative modulation of invariant natural killer T cell responses to glycolipid antigens by p38 MAP kinase.
International immunopharmacology 20100901
-
Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion.
Molecular carcinogenesis 20100901
-
Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100901
-
Diallyl disulfide induces apoptosis in human leukemia HL-60 cells through activation of JNK mediated by reactive oxygen.
Die Pharmazie 20100901
-
HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity.
Journal of cellular and molecular medicine 20100801
-
Pyrogallol-induced As4.1 juxtaglomerular cell death is attenuated by MAPK inhibitors via preventing GSH depletion.
Archives of toxicology 20100801
-
Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H(2)O(2)-induced apoptosis.
Free radical biology & medicine 20100801
-
JNK1 and JNK2 differently regulate IL-12 production in THP-1 macrophage cells.
Cytokine 20100801
-
Novel plasminogen activator inhibitor-1-derived peptide protects against impairment of cerebrovasodilation after photothrombosis through inhibition of JNK MAPK.
American journal of physiology. Regulatory, integrative and comparative physiology 20100801
-
Effect of hyperthermia in combination with TRAIL on the JNK-Bim signal transduction pathway and growth of xenograft tumors.
Journal of cellular biochemistry 20100801
-
The mechanism of fucoidan-induced apoptosis in leukemic cells: involvement of ERK1/2, JNK, glutathione, and nitric oxide.
Molecular carcinogenesis 20100801
-
Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages.
British journal of pharmacology 20100801
-
N-acetylcysteine protects alveolar epithelial cells from hydrogen peroxide-induced apoptosis through scavenging reactive oxygen species and suppressing c-Jun N-terminal kinase.
Experimental lung research 20100801
-
Control of TrkA-induced cell death by JNK activation and differential expression of TrkA upon DNA damage.
Molecules and cells 20100801
-
8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.
World journal of gastroenterology 20100721
-
Amphetamines induce tissue factor and impair tissue factor pathway inhibitor: role of dopamine receptor type 4.
European heart journal 20100701
-
Rolipram and SP600125 suppress the early increase in PTP1B expression during cerulein-induced pancreatitis in rats.
Pancreas 20100701
-
Mycophenolic acid attenuates tumor necrosis factor-alpha-induced endothelin-1 production in human aortic endothelial cells.
Atherosclerosis 20100701
-
Down-expression of PGC-1alpha partially mediated by JNK/c-Jun through binding to CRE site during apoptotic procedure in cerebellar granule neurons.
Journal of neuroscience research 20100701
-
Caspases-2 and -8 are involved in the presenilin1/gamma-secretase-dependent cleavage of amyloid precursor protein after the induction of apoptosis.
Journal of neuroscience research 20100701
-
Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways.
Journal of cellular physiology 20100701
-
Chloramphenicol causes mitochondrial stress, decreases ATP biosynthesis, induces matrix metalloproteinase-13 expression, and solid-tumor cell invasion.
Toxicological sciences : an official journal of the Society of Toxicology 20100701
-
JNK inhibition arrests cotranslational degradation.
Biochimica et biophysica acta 20100701
-
Interaction of Pdcd4 with eIF4E inhibits the metastatic potential of hepatocellular carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100701
-
c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.
Toxicology and applied pharmacology 20100701
-
PAI-1-derived peptide EEIIMD prevents impairment of cerebrovasodilation by augmenting p38 MAPK upregulation after cerebral hypoxia/ischemia.
American journal of physiology. Heart and circulatory physiology 20100701
-
Regulation of (pro)renin receptor expression by glucose-induced mitogen-activated protein kinase, nuclear factor-kappaB, and activator protein-1 signaling pathways.
Endocrinology 20100701
-
Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells.
Free radical research 20100701
-
Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor.
Endocrinology 20100701
-
Mechanisms of IL-12 synthesis by human dendritic cells treated with the chemical sensitizer NiSO4.
Journal of immunology (Baltimore, Md. : 1950) 20100701
-
The JNK pathway modulates expression and phosphorylation of 4E-BP1 in MIN6 pancreatic beta-cells under oxidative stress conditions.
Cell biochemistry and function 20100701
-
p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17.
The Journal of biological chemistry 20100625
-
Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.
Biochemical pharmacology 20100615
-
Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.
Toxicology and applied pharmacology 20100615
-
Glucosamine regulation of LPS-mediated inflammation in human bronchial epithelial cells.
European journal of pharmacology 20100610
-
Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.
Blood 20100610
-
The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP.
Chemico-biological interactions 20100607
-
Suppression of the androgen receptor function by quercetin through protein-protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells.
Molecular and cellular biochemistry 20100601
-
Manganese-mediated up-regulation of HIF-1alpha protein in Hep2 human laryngeal epithelial cells via activation of the family of MAPKs.
Toxicology in vitro : an international journal published in association with BIBRA 20100601
-
Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38.
Cutaneous and ocular toxicology 20100601
-
JNK pathway is required for TNCB-induced IL-18 expression in murine keratinocytes.
Toxicology in vitro : an international journal published in association with BIBRA 20100601
-
Protective effect of sulforaphane on human vascular endothelial cells against lipopolysaccharide-induced inflammatory damage.
Cardiovascular toxicology 20100601
-
The antimicrobial peptide LL37 induces the migration of human pulp cells: a possible adjunct for regenerative endodontics.
Journal of endodontics 20100601
-
Inhibition of the JNK signal cascade conserves hearing against electrode insertion trauma-induced loss.
Cochlear implants international 20100601
-
Role of oxidative stress and MAPK signaling in reference moist smokeless tobacco-induced HOK-16B cell death.
Toxicology letters 20100519
-
Mycophenolic acid inhibits the phosphorylation of NF-kappaB and JNKs and causes a decrease in IL-8 release in H2O2-treated human renal proximal tubular cells.
Chemico-biological interactions 20100514
-
Resveratrol enhances perforin expression and NK cell cytotoxicity through NKG2D-dependent pathways.
Journal of cellular physiology 20100501
-
Palmitic acid promotes endothelial progenitor cells apoptosis via p38 and JNK mitogen-activated protein kinase pathways.
Atherosclerosis 20100501
-
Human cytomegalovirus induces caspase-dependent apoptosis of megakaryocytic CHRF-288-11 cells by activating the JNK pathway.
International journal of hematology 20100501
-
Differential functions of growth factor receptor-bound protein 7 (GRB7) and its variant GRB7v in ovarian carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100501
-
SP600125, an inhibitor of c-Jun NH2-terminal kinase, blocks expression of angiotensin II-induced monocyte chemoattractant protein-1 in human mesangial cells.
World journal of pediatrics : WJP 20100501
-
TNF-alpha reduces the Na+/K+ ATPase activity in LLC-PK1 cells by activating caspases and JNK and inhibiting NF-kappaB.
Cell biology international 20100427
-
Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts.
Toxicology and applied pharmacology 20100415
-
Blockage of JNK pathway enhances arsenic trioxide-induced apoptosis in human keratinocytes.
Toxicology and applied pharmacology 20100415
-
Ghrelin inhibits cell apoptosis induced by lipotoxicity in pancreatic beta-cell line.
Regulatory peptides 20100409
-
The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes.
Leukemia research 20100401
-
Betacellulin protects from pancreatitis by activating stress-activated protein kinase.
Gastroenterology 20100401
-
Regulation of multidrug resistance protein 1 by tumor necrosis factor alpha in cultured glial cells: involvement of nuclear factor-kappaB and c-Jun N-terminal kinase signaling pathways.
Molecular pharmacology 20100401
-
Lead induces the expression of endoplasmic reticulum chaperones GRP78 and GRP94 in vascular endothelial cells via the JNK-AP-1 pathway.
Toxicological sciences : an official journal of the Society of Toxicology 20100401
-
Peritonitis-induced peroxynitrite and lung damage depends on c-Jun NH2-terminal kinase signaling of hematopoietic cells.
Critical care medicine 20100401
-
Testosterone membrane-initiated action in breast cancer cells: Interaction with the androgen signaling pathway and EPOR.
Molecular oncology 20100401
-
Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes.
The Journal of toxicological sciences 20100401
-
Heme oxygenase-1 mediates nicotine- and lipopolysaccharide-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in human periodontal ligament cells.
Journal of periodontal research 20100401
-
Proinflammatory effects of muramyldipeptide on human gingival fibroblasts.
Journal of periodontal research 20100401
-
Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-kappaB activation, and induces human osteoblastic and chondrocytic differentiation.
Chemico-biological interactions 20100330
-
Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells.
Toxicology letters 20100315
-
Close association of p38 and JNK with plasminogen-dependent upregulation of PAI-1 in rat astrocytes in vitro.
Neuroscience letters 20100303
-
Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
Biochemistry 20100302
-
Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus.
Cell death and differentiation 20100301
-
Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation.
Neuroscience research 20100301
-
Estradiol protects the cochlea against gentamicin ototoxicity through inhibition of the JNK pathway.
Hearing research 20100301
-
Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3.
Endocrinology 20100301
-
Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1.
Free radical research 20100301
-
Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation.
Cancer letters 20100227
-
Surfactin induces apoptosis in human breast cancer MCF-7 cells through a ROS/JNK-mediated mitochondrial/caspase pathway.
Chemico-biological interactions 20100212
-
Regulation of neurite outgrowth by interactions between the scaffolding protein, JNK-associated leucine zipper protein, and neuronal growth-associated protein superior cervical ganglia clone 10.
The Journal of biological chemistry 20100205
-
Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation.
Toxicology in vitro : an international journal published in association with BIBRA 20100201
-
Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling.
Molecular carcinogenesis 20100201
-
Mechanisms involved in ultrafine carbon black-induced release of IL-6 from primary rat epithelial lung cells.
Toxicology in vitro : an international journal published in association with BIBRA 20100201
-
Anti-adipogenesis by 6-thioinosine is mediated by downregulation of PPAR gamma through JNK-dependent upregulation of iNOS.
Cellular and molecular life sciences : CMLS 20100201
-
Inhibition of Foxo1 mediates protective effects of ghrelin against lipotoxicity in MIN6 pancreatic beta-cells.
Peptides 20100201
-
Effects of UVA on TNF-alpha, IL-1beta, and IL-10 expression levels in human keratinocytes and intervention studies with an antioxidant and a JNK inhibitor.
Photodermatology, photoimmunology & photomedicine 20100201
-
Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death.
Cell death & disease 20100201
-
Induction of tissue inhibitor of matrix metalloproteinase-2 by cholesterol depletion leads to the conversion of proMMP-2 into active MMP-2 in human dermal fibroblasts.
Experimental & molecular medicine 20100131
-
Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species.
Oncogene 20100128
-
Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells.
Journal of cellular physiology 20100101
-
Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition.
Gastroenterology 20100101
-
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.
Drug metabolism and disposition: the biological fate of chemicals 20100101
-
c-Jun N-terminal kinase 1 is required for cordycepin-mediated induction of G2/M cell-cycle arrest via p21WAF1 expression in human colon cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
-
Apoptosis induction in BEFV-infected Vero and MDBK cells through Src-dependent JNK activation regulates caspase-3 and mitochondria pathways.
Veterinary research 20100101
-
JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 20100101
-
Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathways in skin epidermal cell line.
Toxicological sciences : an official journal of the Society of Toxicology 20100101
-
(-)-Epigallocatechin-3-gallate decreases thrombin/paclitaxel-induced endothelial tissue factor expression via the inhibition of c-Jun terminal NH2 kinase phosphorylation.
Biochemical and biophysical research communications 20100101
-
Transcriptional regulation of the presenilin-1 gene controls gamma-secretase activity.
Frontiers in bioscience (Elite edition) 20100101
-
Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors.
Molecular pain 20100101
-
Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils.
Journal of inflammation (London, England) 20100101
-
Induction of LRF-1/ATF3 by vasopressin in hepatocytes: role of MAP kinases.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
-
Inhibition of c-Jun N-terminal kinase by SP600125: a cDNA microarray analysis.
Cancer genomics & proteomics 20100101
-
Pharmacological inhibition of c-Jun N-terminal kinase signaling prevents cardiomyopathy caused by mutation in LMNA gene.
Biochimica et biophysica acta 20100101
-
Resveratrol differentially modulates inflammatory responses of microglia and astrocytes.
Journal of neuroinflammation 20100101
-
Protective role of taurine against arsenic-induced mitochondria-dependent hepatic apoptosis via the inhibition of PKCdelta-JNK pathway.
PloS one 20100101
-
Doxorubicin induces apoptosis in H9c2 cardiomyocytes: role of overexpressed eukaryotic translation initiation factor 5A.
Biological & pharmaceutical bulletin 20100101
-
Platelet-activating factor receptor mediates oxidized low density lipoprotein-induced migration of bone marrow-derived mesenchymal stem cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
-
c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.
Molecular cancer 20100101
-
Ligand-independent activation of the androgen receptor by insulin-like growth factor-I and the role of the MAPK pathway in skeletal muscle cells.
Molecules and cells 20091231
-
NMDA receptors are involved in upstream of the spinal JNK activation in morphine antinociceptive tolerance.
Neuroscience letters 20091225
-
Role of the nuclear receptors HNF4 alpha, PPAR alpha, and LXRs in the TNF alpha-mediated inhibition of human apolipoprotein A-I gene expression in HepG2 cells.
Biochemistry 20091222
-
Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
Journal of neuro-oncology 20091201
-
Glycosaminoglycans and syndecan-4 are involved in SDF-1/CXCL12-mediated invasion of human epitheloid carcinoma HeLa cells.
Biochimica et biophysica acta 20091201
-
Regulation of Lhb and Egr1 gene expression by GNRH pulses in rat pituitaries is both c-Jun N-terminal kinase (JNK)- and extracellular signal-regulated kinase (ERK)-dependent.
Biology of reproduction 20091201
-
c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation.
The Journal of pharmacology and experimental therapeutics 20091201
-
ROS inhibit the expression of testicular steroidogenic enzyme genes via the suppression of Nur77 transactivation.
Free radical biology & medicine 20091201
-
Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.
American journal of physiology. Heart and circulatory physiology 20091201
-
Local secretion of urocortin 1 promotes microvascular permeability during lipopolysaccharide-induced inflammation.
Endocrinology 20091201
-
Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
Endocrinology 20091201
-
Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20091201
-
Triclosan inhibits tumor necrosis factor-alpha-stimulated urokinase production in human gingival fibroblasts.
Journal of periodontal research 20091201
-
Abeta(31-35)-induced neuronal apoptosis is mediated by JNK-dependent extrinsic apoptosis pathway.
Neuroscience bulletin 20091201
-
Basal c-Jun NH2-terminal protein kinase activity is essential for survival and proliferation of T-cell acute lymphoblastic leukemia cells.
Molecular cancer therapeutics 20091201
-
c-Jun N-terminal kinase negatively regulates epidermal growth factor-induced cyclooxygenase-2 expression in oral squamous cell carcinoma cell lines.
European journal of oral sciences 20091201
-
Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
The Journal of biological chemistry 20091127
-
Enterobacter sakazakii targets DC-SIGN to induce immunosuppressive responses in dendritic cells by modulating MAPKs.
Journal of immunology (Baltimore, Md. : 1950) 20091115
-
HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products.
Journal of immunology (Baltimore, Md. : 1950) 20091115
-
Constitutive and oxidative-stress-induced expression of VEGF in the RPE are differently regulated by different Mitogen-activated protein kinases.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20091101
-
Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.
American journal of respiratory and critical care medicine 20091101
-
Inhibition of the JNK signalling pathway enhances proteasome inhibitor-induced apoptosis of kidney cancer cells by suppression of BAG3 expression.
British journal of pharmacology 20091101
-
Glucose-regulated protein 78 inhibits scavenger receptor A-mediated internalization of acetylated low density lipoprotein.
Journal of molecular and cellular cardiology 20091101
-
Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy.
American journal of physiology. Gastrointestinal and liver physiology 20091101
-
JNK inhibitor protects dopaminergic neurons by reducing COX-2 expression in the MPTP mouse model of subacute Parkinson's disease.
Journal of the neurological sciences 20091015
-
Cordycepin causes p21WAF1-mediated G2/M cell-cycle arrest by regulating c-Jun N-terminal kinase activation in human bladder cancer cells.
Archives of biochemistry and biophysics 20091015
-
Tpl2 is a key mediator of arsenite-induced signal transduction.
Cancer research 20091015
-
PDGF stimulation of Müller cell proliferation: Contributions of c-JNK and the PI3K/Akt pathway.
Biochemical and biophysical research communications 20091009
-
Effect of TLR3 and TLR7 activation in uterine NK cells from non-obese diabetic (NOD) mice.
Journal of reproductive immunology 20091001
-
JNK-dependent NFATc1 pathway positively regulates IL-13 gene expression induced by (-)-epigallocatechin-3-gallate in human basophilic KU812 cells.
Free radical biology & medicine 20091001
-
Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Prostaglandins, leukotrienes, and essential fatty acids 20091001
-
Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: role of NF-kappa B, p38 and JNK MAPK pathway.
Toxicology and applied pharmacology 20091001
-
Anti-apoptotic action of hydrogen sulfide is associated with early JNK inhibition.
Cell biology international 20091001
-
Glucosamine inhibits IL-1beta-mediated IL-8 production in prostate cancer cells by MAPK attenuation.
Journal of cellular biochemistry 20091001
-
Ketoconazole-induced JNK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells.
Toxicology in vitro : an international journal published in association with BIBRA 20091001
-
Syndecan-1 and syndecan-4 are involved in RANTES/CCL5-induced migration and invasion of human hepatoma cells.
Biochimica et biophysica acta 20091001
-
Characterization of CRTAM gene promoter: AP-1 transcription factor control its expression in human T CD8 lymphocytes.
Molecular immunology 20091001
-
A JNK inhibitor SP600125 induces defective cytokinesis and enlargement in P19 embryonal carcinoma cells.
Cell biochemistry and function 20091001
-
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nature chemical biology 20091001
-
[Effects of sp600125 on acetaldehyde stimulated hepatic stellate cells].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20091001
-
JNK inhibitor SP600125 promotes the formation of polymerized tubulin, leading to G2/M phase arrest, endoreduplication, and delayed apoptosis.
Experimental & molecular medicine 20090930
-
SP600125, an inhibitor of Jnk pathway, reduces viability of relatively resistant cancer cells to doxorubicin.
Biochemical and biophysical research communications 20090925
-
JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis.
The Journal of biological chemistry 20090925
-
1,3-Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: Involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway.
Toxicology letters 20090910
-
FGF2 stimulates the proliferation of human mesenchymal stem cells through the transient activation of JNK signaling.
FEBS letters 20090903
-
Silencing of TNF-alpha receptors coordinately suppresses TNF-alpha expression through NF-kappaB activation blockade in THP-1 macrophage.
FEBS letters 20090903
-
Interferon-gamma priming is involved in the activation of arginase by oligodeoxinucleotides containing CpG motifs in murine macrophages.
Immunology 20090901
-
Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways.
Molecular biology reports 20090901
-
Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin.
Oral oncology 20090901
-
Biphasic effect of cadmium on cell proliferation in human embryo lung fibroblast cells and its molecular mechanism.
Toxicology in vitro : an international journal published in association with BIBRA 20090901
-
Involvement of C-jun NH2-terminal kinase and apoptosis induced factor in apoptosis induced by deglycosylated bleomycin in laryngeal carcinoma cells.
Cell biology international 20090901
-
Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner.
Hepatology (Baltimore, Md.) 20090901
-
Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression.
American journal of physiology. Cell physiology 20090901
-
The JNK MAP kinase pathway contributes to the development of endotoxin-induced diaphragm caspase activation.
American journal of physiology. Regulatory, integrative and comparative physiology 20090901
-
Oncogenic Ras signals through activation of both phosphoinositide 3-kinase and Rac1 to induce c-Jun NH2-terminal kinase-mediated, caspase-independent cell death.
Molecular cancer research : MCR 20090901
-
[Pathogenetic role of tissue factor in endothelial-injury in graft-versus-host disease].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20090901
-
Arachidonic acid-induced apoptosis of human neuroblastoma SK-N-SH cells is mediated through mitochondrial alteration elicited by ROS and Ca(2+)-evoked activation of p38alpha MAPK and JNK1.
Toxicology 20090821
-
Fluoride-induced cyclooxygenase-2 expression and prostaglandin E2 production in A549 human pulmonary epithelial cells.
Toxicology letters 20090810
-
Activation of JNK and PAK2 is essential for citrinin-induced apoptosis in a human osteoblast cell line.
Environmental toxicology 20090801
-
Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells.
Biochimica et biophysica acta 20090801
-
Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis.
Biochemical pharmacology 20090801
-
Nobiletin, a dietary phytochemical, inhibits vascular smooth muscle cells proliferation via calcium-mediated c-Jun N-terminal kinases pathway.
European journal of pharmacology 20090801
-
Oxidized {alpha}1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
American journal of physiology. Lung cellular and molecular physiology 20090801
-
Genistein inhibits cell growth by modulating various mitogen-activated protein kinases and AKT in cervical cancer cells.
Annals of the New York Academy of Sciences 20090801
-
Ginkgolide B induces apoptosis via activation of JNK and p21-activated protein kinase 2 in mouse embryonic stem cells.
Annals of the New York Academy of Sciences 20090801
-
Gallic acid induces neuronal cell death through activation of c-Jun N-terminal kinase and downregulation of Bcl-2.
Annals of the New York Academy of Sciences 20090801
-
Cobalt protoporphyrin inhibition of lipopolysaccharide or lipoteichoic acid-induced nitric oxide production via blocking c-Jun N-terminal kinase activation and nitric oxide enzyme activity.
Chemico-biological interactions 20090715
-
Role of Paris PM(2.5) components in the pro-inflammatory response induced in airway epithelial cells.
Toxicology 20090710
-
Regulation of c-Fos and c-Jun gene expression by phospholipase C activity in adult cardiomyocytes.
Molecular and cellular biochemistry 20090701
-
Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells.
Journal of cellular physiology 20090701
-
Upregulation of proinflammatory cytokines and NO production in BV-activated avian macrophage-like cell line (HD11) requires MAPK and NF-kappaB pathways.
International immunopharmacology 20090701
-
Block-copolymer micelles as carriers of cell signaling modulators for the inhibition of JNK in human islets of Langerhans.
Biomaterials 20090701
-
Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells.
Carcinogenesis 20090701
-
Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.
Chemical biology & drug design 20090701
-
JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090701
-
Cadmium stimulates the expression of vascular cell adhesion molecule-1 (VCAM-1) via p38 mitogen-activated protein kinase (MAPK) and JNK activation in cerebrovascular endothelial cells.
Journal of pharmacological sciences 20090701
-
Effects of polychlorinated biphenyls on the neutrophil NADPH oxidase system.
Toxicology letters 20090622
-
NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells.
Toxicology letters 20090622
-
Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.
The Journal of biological chemistry 20090619
-
Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes.
Free radical biology & medicine 20090615
-
Activation of ERK and JNK signaling pathways by mycotoxin citrinin in human cells.
Toxicology and applied pharmacology 20090615
-
Zinc protoporphyrin inhibition of lipopolysaccharide-, lipoteichoic acid-, and peptidoglycan-induced nitric oxide production through stimulating iNOS protein ubiquitination.
Toxicology and applied pharmacology 20090615
-
Characterization of natural killer cells in nonobese diabetic/severely compromised immunodeficient mice during pregnancy.
Fertility and sterility 20090601
-
Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway.
The international journal of biochemistry & cell biology 20090601
-
The inhibition of JNK and p38 MAPKs downregulates IL-10 and differentially affects c-Jun gene expression in human monocytes.
Immunopharmacology and immunotoxicology 20090601
-
Inhibition of uncoupling protein 2 by genipin reduces insulin-stimulated glucose uptake in 3T3-L1 adipocytes.
Archives of biochemistry and biophysics 20090601
-
The protein synthesis inhibitor anisomycin induces macrophage apoptosis in rabbit atherosclerotic plaques through p38 mitogen-activated protein kinase.
The Journal of pharmacology and experimental therapeutics 20090601
-
Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 20090601
-
Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.
The Journal of clinical investigation 20090601
-
Acetaminophen and lipopolysaccharide act in synergy for the production of pro-inflammatory cytokines in murine RAW264.7 macrophages.
Journal of immunotoxicology 20090601
-
PHR regulates growth cone pausing at intermediate targets through microtubule disassembly.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520
-
Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activity.
Free radical biology & medicine 20090515
-
Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent.
Toxicology and applied pharmacology 20090515
-
Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression.
Cancer chemotherapy and pharmacology 20090501
-
JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090501
-
JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand.
Gut 20090501
-
Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase.
The Journal of biological chemistry 20090501
-
JNK is constitutively active in mantle cell lymphoma: cell cycle deregulation and polyploidy by JNK inhibitor SP600125.
The Journal of pathology 20090501
-
Echographic detection of diethylnitrosamine-induced liver tumors in rats and the effect of the intratumoral injection of an inhibitor of c-Jun N-terminal kinase.
Journal of gastroenterology and hepatology 20090501
-
NaF activates MAPKs and induces apoptosis in odontoblast-like cells.
Journal of dental research 20090501
-
Regulation of expression of matrix metalloproteinase-9 by JNK in Raw 264.7 cells: presence of inhibitory factor(s) suppressing MMP-9 induction in serum and conditioned media.
Experimental & molecular medicine 20090430
-
Inhibition of JNK enhances TGF-beta1-activated Smad2 signaling in mouse embryonic lung.
Pediatric research 20090401
-
Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells.
The Journal of pharmacology and experimental therapeutics 20090401
-
The TAK1-JNK cascade is required for IRF3 function in the innate immune response.
Cell research 20090401
-
Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.
Neurobiology of disease 20090401
-
N-acetyl cysteine mediates protection from 2-hydroxyethyl methacrylate induced apoptosis via nuclear factor kappa B-dependent and independent pathways: potential involvement of JNK.
Toxicological sciences : an official journal of the Society of Toxicology 20090401
-
TGF-beta effects on airway smooth muscle cell proliferation, VEGF release and signal transduction pathways.
Respirology (Carlton, Vic.) 20090401
-
Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways.
Placenta 20090401
-
Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling.
American journal of physiology. Cell physiology 20090401
-
A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration.
Nature neuroscience 20090401
-
Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts.
International journal of molecular medicine 20090401
-
Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway.
The FEBS journal 20090401
-
Neuroprotection by c-Jun NH2-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry.
Neuroscience 20090331
-
Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells.
Biochemical and biophysical research communications 20090320
-
Ultrafine particles from diesel engines induce vascular oxidative stress via JNK activation.
Free radical biology & medicine 20090315
-
Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress.
FEBS letters 20090304
-
Glial fibrillary acidic protein promoter targets pancreatic stellate cells.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090301
-
Role of mitogen-activated protein kinase cascades in inducible nitric oxide synthase expression by lipopolysaccharide in a rat Schwann cell line.
Neurochemical research 20090301
-
Inhibition of the activity of Rho-kinase reduces cardiomyocyte apoptosis in heart ischemia/reperfusion via suppressing JNK-mediated AIF translocation.
Clinica chimica acta; international journal of clinical chemistry 20090301
-
Metallic haptens induce differential phenotype of human dendritic cells through activation of mitogen-activated protein kinase and NF-kappaB pathways.
Toxicology in vitro : an international journal published in association with BIBRA 20090301
-
Blockage by SP600125 of Fcepsilon receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signalling pathway.
Journal of biochemistry 20090301
-
Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion.
Toxicology in vitro : an international journal published in association with BIBRA 20090301
-
Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells.
European journal of pharmacology 20090301
-
TNF-alpha reduces the level of Staphylococcus epidermidis internalization by bovine endothelial cells.
FEMS microbiology letters 20090301
-
C-jun N-terminal kinase-mediated signaling is essential for Staphylococcus aureus-induced U937 apoptosis.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20090301
-
Role of MAPKs in platinum-induced neuronal apoptosis.
Neurotoxicology 20090301
-
The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells.
Oncogene 20090212
-
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Amino acids 20090201
-
Daxx functions as a scaffold of a protein assembly constituted by GLUT4, JNK1 and KIF5B.
Journal of cellular physiology 20090201
-
Differential roles of MAPKs and MSK1 signalling pathways in the regulation of c-Jun during phenylephrine-induced cardiac myocyte hypertrophy.
Molecular and cellular biochemistry 20090201
-
c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer.
Carcinogenesis 20090201
-
Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.
American journal of physiology. Gastrointestinal and liver physiology 20090201
-
Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway.
Biomedical and environmental sciences : BES 20090201
-
SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression.
FEBS letters 20090105
-
7-Ketocholesterol upregulates interleukin-6 via mechanisms that are distinct from those of tumor necrosis factor-alpha, in vascular smooth muscle cells.
Journal of vascular research 20090101
-
TNF-alpha production in the skin.
Archives of dermatological research 20090101
-
Enhanced induction of LPS-induced fibroblast MCP-1 by interferon-gamma: involvement of JNK and MAPK phosphatase-1.
Cellular immunology 20090101
-
AP-1 and ERK1 but not p38 nor JNK is required for CRPV early protein 2-dependent MMP-9 promoter activation in rabbit epithelial cells.
Virus research 20090101
-
Oxidative stress resistance through blocking Hsp60 translocation followed by SAPK/JNK inhibition in aged human diploid fibroblasts.
Cell biochemistry and function 20090101
-
Induction of apoptosis in human leukemia cells by grape seed extract occurs via activation of c-Jun NH2-terminal kinase.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090101
-
Neuronal injury induces cytokine-induced neutrophil chemoattractant-1 (CINC-1) production in astrocytes.
Journal of pharmacological sciences 20090101
-
Activation of c-Jun N-terminal kinase cascades is involved in part of the neuronal degeneration induced by trimethyltin in cortical neurons of mice.
Journal of pharmacological sciences 20090101
-
Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways.
Molecular vision 20090101
-
Cisplatin primes murine peritoneal macrophages for enhanced expression of nitric oxide, proinflammatory cytokines, TLRs, transcription factors and activation of MAP kinases upon co-incubation with L929 cells.
Immunobiology 20090101
-
The role of c-Jun N-terminal kinases 1/2 in transforming growth factor beta(1)-induced expression of connective tissue growth factor and scar formation in the cornea.
The Journal of international medical research 20090101
-
The JNK pathway amplifies and drives subcellular changes in tau phosphorylation.
Neuropharmacology 20090101
-
Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members.
PloS one 20090101
-
The proliferation and migration effects of huangqi on RSC96 Schwann cells.
The American journal of Chinese medicine 20090101
-
Protective effects of SP600125 in a diet-induced rat model of non-alcoholic steatohepatitis.
Scandinavian journal of gastroenterology 20090101
-
Transcription of the protein kinase C-delta gene is activated by JNK through c-Jun and ATF2 in response to the anticancer agent doxorubicin.
Experimental & molecular medicine 20081231
-
Cardiotrophin-1 induces intercellular adhesion molecule-1 expression by nuclear factor kappaB activation in human umbilical vein endothelial cells.
Chinese medical journal 20081220
-
Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
Cancer research 20081215
-
Brefeldin A activates CHOP promoter at the AARE, ERSE and AP-1 elements.
Molecular and cellular biochemistry 20081201
-
Realgar-induced differentiation is associated with MAPK pathways in HL-60 cells.
Cell biology international 20081201
-
Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.
Neuropharmacology 20081201
-
o,p'-DDT induces cyclooxygenase-2 gene expression in murine macrophages: Role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways.
Toxicology and applied pharmacology 20081201
-
Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis.
Neurobiology of disease 20081201
-
In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway.
Apoptosis : an international journal on programmed cell death 20081201
-
Phosphatidylinositol acts through mitogen-activated protein kinase to stimulate hepatic apolipoprotein A-I secretion.
Metabolism: clinical and experimental 20081201
-
[Impact of PTEN gene knockout in human breast carcinoma MCF-7 cells on activity of JNK pathway].
Ai zheng = Aizheng = Chinese journal of cancer 20081201
-
[The influence of JNK inhibitor on hemodynamics after ischemia/reperfusion injury to the heart in rats].
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20081201
-
Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells.
Journal of endocrinological investigation 20081201
-
JNK1 regulates histone acetylation in trigeminal neurons following chemical stimulation.
Biochemical and biophysical research communications 20081128
-
Reciprocal influences of CB1 cannabinoid receptor agonists on ERK and JNK signalling in N1E-115 cells.
FEBS letters 20081126
-
Virtual screening to successfully identify novel janus kinase 3 inhibitors: a sequential focused screening approach.
Journal of medicinal chemistry 20081113
-
Selenium attenuates pro-inflammatory gene expression in macrophages.
Molecular nutrition & food research 20081101
-
Egr-1 mRNA induction by medium flow involves mRNA stabilization and is enhanced by the p38 inhibitor SB203580 in osteoblast-like cells.
Acta physiologica (Oxford, England) 20081101
-
Initiation of caspase-independent death in mouse mesangial cells by Cd2+: involvement of p38 kinase and CaMK-II.
Journal of cellular physiology 20081101
-
IL-6/sIL-6R enhances cathepsin B and L production via caveolin-1-mediated JNK-AP-1 pathway in human gingival fibroblasts.
Journal of cellular physiology 20081101
-
Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition.
Gut 20081101
-
Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line.
Experimental cell research 20081101
-
Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling.
The Journal of steroid biochemistry and molecular biology 20081101
-
Mechanism of signal transduction in tumor necrosis factor-like weak inducer of apoptosis-induced matrix degradation by MMP-3 upregulation in disc tissues.
Spine 20081101
-
Activation of peripheral ephrinBs/EphBs signaling induces hyperalgesia through a MAPKs-mediated mechanism in mice.
Pain 20081031
-
Peroxisome proliferator-activated receptor gamma down-regulates follistatin in intestinal epithelial cells through SP1.
The Journal of biological chemistry 20081031
-
IL-18 enhances ULBP2 expression through the MAPK pathway in leukemia cells.
Immunology letters 20081030
-
The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.
Journal of cellular physiology 20081001
-
(-)-Epigallocatechin gallate inhibits basic fibroblast growth factor-stimulated interleukin-6 synthesis in osteoblasts.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081001
-
Expression and regulation of c-Jun N-terminal kinase (JNK) in endometrial cells in vivo and in vitro.
Histochemistry and cell biology 20081001
-
TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells.
Cancer investigation 20081001
-
The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism.
Molecular pharmacology 20081001
-
A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines.
Leukemia 20081001
-
Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5.
Free radical biology & medicine 20081001
-
A combination of sulindac and arsenic trioxide synergistically induces apoptosis in human lung cancer H1299 cells via c-Jun NH2-terminal kinase-dependent Bcl-xL phosphorylation.
Lung cancer (Amsterdam, Netherlands) 20080901
-
Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling.
The Journal of pharmacology and experimental therapeutics 20080901
-
6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-alpha mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.
Biochemical and biophysical research communications 20080829
-
Activation of endothelial cells to pathological status by down-regulation of connexin43.
Cardiovascular research 20080801
-
Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080801
-
Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies.
The Biochemical journal 20080801
-
Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.
The Journal of biological chemistry 20080801
-
Characterization of early events involved in human dendritic cell maturation induced by sensitizers: cross talk between MAPK signalling pathways.
Toxicology and applied pharmacology 20080801
-
The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease.
Neuroscience research 20080801
-
JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis.
Pigment cell & melanoma research 20080801
-
BDNF induces late-phase LTP of C-fiber evoked field potentials in rat spinal dorsal horn.
Experimental neurology 20080801
-
Differential roles of p38-MAPK and JNKs in mediating early protection or apoptosis in the hyperthermic perfused amphibian heart.
The Journal of experimental biology 20080801
-
Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases.
Oncology reports 20080801
-
P-glycoprotein down-regulates expression of breast cancer resistance protein in a drug-free state.
FEBS letters 20080723
-
Piceatannol attenuates hydrogen-peroxide- and peroxynitrite-induced apoptosis of PC12 cells by blocking down-regulation of Bcl-XL and activation of JNK.
The Journal of nutritional biochemistry 20080701
-
Dexamethasone-induced expression of endothelial mitogen-activated protein kinase phosphatase-1 involves activation of the transcription factors activator protein-1 and 3',5'-cyclic adenosine 5'-monophosphate response element-binding protein and the generation of reactive oxygen species.
Endocrinology 20080701
-
JNK as a positive regulator of angiogenic potential in endothelial cells.
Cell biology international 20080701
-
Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors.
American journal of physiology. Heart and circulatory physiology 20080701
-
c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice.
Cancer research 20080701
-
Differential bortezomib sensitivity in head and neck cancer lines corresponds to proteasome, nuclear factor-kappaB and activator protein-1 related mechanisms.
Molecular cancer therapeutics 20080701
-
Cytosolic accumulation of gammaH2AX is associated with tropomyosin-related kinase A-induced cell death in U2OS cells.
Experimental & molecular medicine 20080630
-
Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells.
Cancer letters 20080618
-
The toxic effect of pyrrolizidine alkaloid clivorine on the human embryonic kidney 293 cells and its primary mechanism.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080601
-
Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
Toxicological sciences : an official journal of the Society of Toxicology 20080601
-
Prevotella intermedia induces matrix metalloproteinase-9 expression in human periodontal ligament cells.
FEMS microbiology letters 20080601
-
Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080601
-
25-hydroxycholesterol induces mitochondria-dependent apoptosis via activation of glycogen synthase kinase-3beta in PC12 cells.
Free radical research 20080601
-
Pharmacological inhibitors of JNK and ERK kinases SP600125 and U0126 are not appropriate tools for studies of drug metabolism because they activate aryl hydrocarbon receptor.
General physiology and biophysics 20080601
-
[Redox-dependent regulation of apoptosis as a function of intracellular reactive oxygen species in oxidative stress].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080601
-
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury.
The Journal of biological chemistry 20080516
-
JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro.
American journal of physiology. Endocrinology and metabolism 20080501
-
Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells.
Laboratory investigation; a journal of technical methods and pathology 20080501
-
Cruzipain and SP600125 induce p38 activation, alter NO/arginase balance and favor the survival of Trypanosoma cruzi in macrophages.
Acta tropica 20080501
-
In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity.
Anesthesia and analgesia 20080501
-
The JNK signaling pathway is involved in sodium-selenite-induced apoptosis mediated by reactive oxygen in HepG2 cells.
Cancer biology & therapy 20080501
-
Role of recombinant mitogen-activated protein kinases JNK and p38 in the regulation of apoptosis in blood mononuclear cells under conditions of oxidative stress in vitro.
Bulletin of experimental biology and medicine 20080501
-
Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells.
Toxicology 20080418
-
Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells.
Toxicology and applied pharmacology 20080415
-
Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1).
Bioorganic & medicinal chemistry 20080415
-
MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
Journal of neurochemistry 20080401
-
Changes in the expression and dynamics of SHP-1 and SHP-2 during cerulein-induced acute pancreatitis in rats.
Biochimica et biophysica acta 20080401
-
Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively.
The FEBS journal 20080401
-
Anti-fas activating antibody enhances trophoblast outgrowth on endometrial epithelial cells by induction of P38 MAPK/JNK-mediated apoptosis.
Placenta 20080401
-
Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts.
Free radical research 20080401
-
Distinct role of c-Jun N-terminal kinase isoforms in human neutrophil apoptosis regulated by tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20080401
-
[Effect of staurosporine induced apoptosis of MCF7/GFP-Bax stable cell line on Bax translocation from cytosol into mitochondria].
Yao xue xue bao = Acta pharmaceutica Sinica 20080401
-
Lipopolysaccharide (LPS) of Porphyromonas gingivalis induces IL-1beta, TNF-alpha and IL-6 production by THP-1 cells in a way different from that of Escherichia coli LPS.
Innate immunity 20080401
-
Inhibition of c-Jun N-terminal kinase sensitizes tumor cells to flavonoid-induced apoptosis through down-regulation of JunD.
Toxicology and applied pharmacology 20080315
-
Cytotoxic effects of metal protoporphyrins in glioblastoma cells: roles of albumin, reactive oxygen species, and heme oxygenase-1.
Toxicology letters 20080315
-
Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080315
-
Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301
-
The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper.
Free radical biology & medicine 20080301
-
Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice.
Hepatology (Baltimore, Md.) 20080301
-
Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells.
FEMS immunology and medical microbiology 20080301
-
Blockade of c-Jun N-terminal kinase activation abrogates hyperglycemia-induced yolk sac vasculopathy in vitro.
American journal of obstetrics and gynecology 20080301
-
Role of mitogen-activated protein kinases in the iNOS production and cytokine secretion by Salmonella enterica serovar Typhimurium porins.
Cytokine 20080301
-
Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.
American journal of physiology. Cell physiology 20080301
-
p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.
Cancer research 20080301
-
Stress-activated protein kinase inhibition to ameliorate lung ischemia reperfusion injury.
The Journal of thoracic and cardiovascular surgery 20080301
-
MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells.
Life sciences 20080227
-
SP600125 inhibits Kv channels through a JNK-independent pathway in cancer cells.
Biochemical and biophysical research communications 20080222
-
The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus.
Virology 20080220
-
c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway.
Journal of cellular biochemistry 20080215
-
Interleukin-1beta gene in orange-spotted grouper, Epinephelus coioides: molecular cloning, expression, biological activities and signal transduction.
Molecular immunology 20080201
-
c-Jun N-terminal kinases trigger both degeneration and neurite outgrowth in primary hippocampal and cortical neurons.
Journal of neurochemistry 20080201
-
Transient and sustained oxidative stress differentially activate the JNK1/2 pathway and apoptotic phenotype in H9c2 cells.
Molecular and cellular biochemistry 20080201
-
JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC.
Experimental cell research 20080201
-
Internalization of Staphylococcus aureus by bovine endothelial cells is associated with the activity state of NF-kappaB and modulated by the pro-inflammatory cytokines TNF-alpha and IL-1beta.
Scandinavian journal of immunology 20080201
-
Rapid and bi-directional regulation of AMPA receptor phosphorylation and trafficking by JNK.
The EMBO journal 20080123
-
JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes.
Biochemical pharmacology 20080115
-
Basal c-Jun N-terminal kinases promote mitotic progression through histone H3 phosphorylation.
Cell cycle (Georgetown, Tex.) 20080115
-
4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.
Biochemistry 20080108
-
Human TAO kinase 1 induces apoptosis in SH-SY5Y cells.
Cell biology international 20080101
-
c-Jun N-terminal kinase inhibitor II (SP600125) activates Mullerian inhibiting substance type II receptor-mediated signal transduction.
Endocrinology 20080101
-
Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors.
Experimental hematology 20080101
-
Inhibitors of c-Jun N-terminal kinases: JuNK no more?
Biochimica et biophysica acta 20080101
-
Role of JNK-dependent serine phosphorylation of paxillin in migration of corneal epithelial cells during wound closure.
Investigative ophthalmology & visual science 20080101
-
High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kappaB and AP-1 activities.
The Journal of endocrinology 20080101
-
Involvement of ROS/ASMase/JNK signalling pathway in inhibiting UVA-induced apoptosis of HaCaT cells by polypeptide from Chlamys farreri.
Free radical research 20080101
-
Inhibition of c-Jun N-terminal kinase pathway attenuates cerebral vasospasm after experimental subarachnoid hemorrhage through the suppression of apoptosis.
Acta neurochirurgica. Supplement 20080101
-
Membrane initiated signaling by 1,25alpha-dihydroxyvitamin D3 in LNCaP prostate cancer cells.
Advances in experimental medicine and biology 20080101
-
JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin.
Journal of inflammation (London, England) 20080101
-
Potentiation by platelet-derived growth factor-BB of FGF-2-stimulated VEGF release in osteoblasts.
Journal of bone and mineral metabolism 20080101
-
NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper.
Journal of biochemical and molecular toxicology 20080101
-
Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts.
Prostaglandins, leukotrienes, and essential fatty acids 20080101
-
Up-regulation of endothelin type B receptors in the human internal mammary artery in culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways.
BMC cardiovascular disorders 20080101
-
Retinoid acid inhibits IL-1-induced iNOS, COX-2 and chemokine production in human chondrocytes.
Immunological investigations 20080101
-
Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells.
Journal of experimental & clinical cancer research : CR 20080101
-
Phorbol 12-myristate 13-acetate-activated protein kinase C increased migratory activity of subconjunctival fibroblasts via stress-activated protein kinase pathways.
Molecular vision 20071221
-
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Proceedings of the National Academy of Sciences of the United States of America 20071218
-
The selectivity of protein kinase inhibitors: a further update.
The Biochemical journal 20071215
-
Nitric oxide dysregulates adipocytokine expression in 3T3-L1 adipocytes.
Biochemical and biophysical research communications 20071207
-
MAPK inhibitors and pifithrin-alpha block cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071201
-
Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK, and P38 regulation.
Journal of pharmacological sciences 20071201
-
Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde.
European journal of pharmacology 20071114
-
Berberine-induced LDLR up-regulation involves JNK pathway.
Biochemical and biophysical research communications 20071103
-
EGCG-targeted p57/KIP2 reduces tumorigenicity of oral carcinoma cells: role of c-Jun N-terminal kinase.
Toxicology and applied pharmacology 20071101
-
Inhibition of ERK and JNK decreases both osmosensitive taurine release and cell proliferation in glioma cells.
Neurochemical research 20071101
-
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
The Biochemical journal 20071101
-
Thimerosal-induced apoptosis in human SCM1 gastric cancer cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation.
Toxicological sciences : an official journal of the Society of Toxicology 20071101
-
Geranylgeranylacetone, an inducer of the 70-kDa heat shock protein (HSP70), elicits unfolded protein response and coordinates cellular fate independently of HSP70.
Molecular pharmacology 20071101
-
Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases.
Molecular and cellular neurosciences 20071101
-
Involvement of c-Jun NH2-terminal kinase and nitric oxide-mediated mitochondria-dependent intrinsic pathway signaling in cardiotoxin-induced muscle cell death: role of testosterone.
Apoptosis : an international journal on programmed cell death 20071101
-
Mechanistic roles of leptin in osteogenic stimulation in thoracic ligament flavum cells.
The Journal of biological chemistry 20071012
-
Long-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase.
The Journal of biological chemistry 20071012
-
Involvement of Na+/H+ exchangers in induction of cyclooxygenase-2 by vacuolar-type (H+)-ATPase inhibitors in RAW 264 cells.
FEBS letters 20071002
-
Involvement of c-Jun N-terminal kinase in G2/M arrest and FasL-mediated apoptosis induced by a novel indoloquinoline derivative, IQDMA, in K562 cells.
Leukemia research 20071001
-
Patterns of kinase activation induced by injury in the murine femoral artery.
The Journal of surgical research 20071001
-
Inhibition of Jun NH2-terminal kinases suppresses the growth of experimental head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20071001
-
Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.
Drug metabolism and pharmacokinetics 20071001
-
House dust mite induces expression of intercellular adhesion molecule-1 in EoL-1 human eosinophilic leukemic cells.
Journal of Korean medical science 20071001
-
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.
The Journal of biological chemistry 20070928
-
Manganese chloride stimulates rat microglia to release hydrogen peroxide.
Toxicology letters 20070910
-
Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells.
Toxicology 20070905
-
IGF-I plus E2 induces proliferation via activation of ROS-dependent ERKs and JNKs in human breast carcinoma cells.
Journal of cellular physiology 20070901
-
Opposing effects of Bad phosphorylation at two distinct sites by Akt1 and JNK1/2 on ischemic brain injury.
Cellular signalling 20070901
-
Inhibition of c-Jun N-terminal kinase in the CA1 region of the dorsal hippocampus blocks extinction of inhibitory avoidance memory.
Behavioural pharmacology 20070901
-
Ras pathway activation in malignant mesothelioma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070901
-
Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.
Free radical biology & medicine 20070815
-
Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
The Journal of biological chemistry 20070803
-
Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF alpha in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis.
Annals of the rheumatic diseases 20070801
-
Effect of JNK inhibition on cisplatin-induced renal damage.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
-
Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells.
International immunopharmacology 20070801
-
Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoic acid-induced iNOS gene expression and NO production in macrophages.
International immunopharmacology 20070801
-
Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.
International immunopharmacology 20070801
-
Interleukin-1beta modulates endogenous thyroid hormone receptor alpha gene transcription in liver cells.
The Journal of endocrinology 20070801
-
Expression and function of mixed lineage kinases in dendritic cells.
International immunology 20070801
-
[Effect of phosphorylated c-Jun expression on COX-2 expression in the substantia nigra of MPTP mouse model of subacute Parkinson disease].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070801
-
Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.
The Biochemical journal 20070715
-
c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons.
Neuroscience 20070713
-
PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK.
Neuroscience letters 20070705
-
Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure.
Gut 20070701
-
Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kappaB and AP-1: IkappaB kinase and c-Jun-N-terminal kinase as respective potential upstream targets.
Carcinogenesis 20070701
-
Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity.
Endocrinology 20070701
-
Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125.
The Journal of pharmacology and experimental therapeutics 20070701
-
TNFalpha induces apoptosis through JNK/Bax-dependent pathway in differentiated, but not naïve PC12 cells.
Cell cycle (Georgetown, Tex.) 20070615
-
Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK.
Cancer letters 20070608
-
Involvement of c-Jun N-terminal kinases activation in diabetic embryopathy.
Biochemical and biophysical research communications 20070608
-
Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.
Neurochemistry international 20070601
-
Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity.
Journal of cellular biochemistry 20070601
-
Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation.
International journal of cancer 20070601
-
Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
European journal of pharmacology 20070601
-
Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells.
Cancer research 20070601
-
Suppression of alloreactivity and allograft rejection by SP600125, a small molecule inhibitor of c-Jun N-terminal kinase.
Transplantation 20070527
-
The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation.
The Journal of biological chemistry 20070518
-
SP600125, a selective JNK inhibitor, protects ischemic renal injury via suppressing the extrinsic pathways of apoptosis.
Life sciences 20070508
-
Thrombin-induced ischemic tolerance is prevented by inhibiting c-jun N-terminal kinase.
Brain research 20070507
-
c-Jun N-terminal kinase mediates AML1-ETO protein-induced connexin-43 expression.
Biochemical and biophysical research communications 20070504
-
Induced secretion of insulin-like growth factor binding protein-1 (IGFBP-1) in human hepatoma cell HepG2 by rubratoxin B.
Archives of toxicology 20070501
-
Inhibitory effect of TNF-alpha on the intestinal absorption of galactose.
Journal of cellular biochemistry 20070501
-
P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells.
Cellular signalling 20070501
-
c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation.
Cell death and differentiation 20070501
-
Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase.
Molecular pharmacology 20070501
-
The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARgamma in rat activated hepatic stellate cell in vitro.
Laboratory investigation; a journal of technical methods and pathology 20070501
-
IKappaB-kinase/nuclear factor-kappaB signaling prevents thermal injury-induced gut damage by inhibiting c-Jun NH2-terminal kinase activation.
Critical care medicine 20070501
-
Celecoxib decreases fatty acid synthase expression via down-regulation of c-Jun N-terminal kinase-1.
Experimental biology and medicine (Maywood, N.J.) 20070501
-
[CD147 stimulates the angiogenesis in rheumatoid synovium via the activation of vascular endothelial growth factor].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070501
-
Hydroquinone, a reactive metabolite of benzene, reduces macrophage-mediated immune responses.
Molecules and cells 20070430
-
Kinetic characterization of human JNK2alpha2 reaction mechanism using substrate competitive inhibitors.
Biochemistry 20070424
-
(-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: inhibition of p44/p42 MAP kinase activation.
FEBS letters 20070403
-
Differential regulation of indoleamine 2,3-dioxygenase by lipopolysaccharide and interferon gamma in murine bone marrow derived dendritic cells.
FEBS letters 20070403
-
Curcumin attenuates glutamate-induced HT22 cell death by suppressing MAP kinase signaling.
Molecular and cellular biochemistry 20070401
-
Inhibition of JNK activation prolongs survival after smoke inhalation from fires.
American journal of physiology. Lung cellular and molecular physiology 20070401
-
TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells--Mechanisms behind a possible new 'hot' cancer treatment.
Biochimica et biophysica acta 20070401
-
Interleukin-1 mediates thermal injury-induced lung damage through C-Jun NH2-terminal kinase signaling.
Critical care medicine 20070401
-
Interleukin-1 in thermal injury: what is next?
Critical care medicine 20070401
-
Flashlamp pulsed-dye laser suppressed TGF-beta1 expression and proliferation in cultured keloid fibroblasts is mediated by MAPK pathway.
Lasers in surgery and medicine 20070401
-
c-Jun N-terminal kinase inhibitor SP600125 modulates the period of mammalian circadian rhythms.
Neuroscience 20070330
-
Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts.
European journal of pharmacology 20070322
-
An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from D-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins.
Life sciences 20070313
-
Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1.
Journal of leukocyte biology 20070301
-
Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070301
-
REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer.
International journal of molecular medicine 20070301
-
Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.
Journal of biochemistry 20070301
-
Bone morphogenetic protein-4 abrogates lumen formation by mammary epithelial cells and promotes invasive growth.
Biochemical and biophysical research communications 20070216
-
p38MAPK activation is involved in androgen-independent proliferation of human prostate cancer cells by regulating IL-6 secretion.
Biochemical and biophysical research communications 20070216
-
Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 20070215
-
Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207
-
Inhibitory effect of obovatol on nitric oxide production and activation of NF-kappaB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells.
European journal of pharmacology 20070205
-
Inhibition of JNK increases survival of transplanted dopamine neurons in Parkinsonian rats.
Cell death and differentiation 20070201
-
Inhibition of c-Jun N-terminal kinase rescues influenza epitope-specific human cytolytic T lymphocytes from activation-induced cell death.
Journal of leukocyte biology 20070201
-
A novel pathway for transcriptional regulation of alpha-synuclein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070201
-
The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice.
Hepatology (Baltimore, Md.) 20070201
-
Macrophage migration inhibitory factor induces MMP-9 expression in macrophages via the MEK-ERK MAP kinase pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20070201
-
Complementary effects of HDAC inhibitor 4-PB on gap junction communication and cellular export mechanisms support restoration of chemosensitivity of PDAC cells.
British journal of cancer 20070115
-
Neurotoxicity assessment using zebrafish.
Journal of pharmacological and toxicological methods 20070101
-
Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells.
Biochemical pharmacology 20070101
-
Dopaminergic and adrenergic toxicities on SK-N-MC human neuroblastoma cells are mediated through G protein signaling and oxidative stress.
Apoptosis : an international journal on programmed cell death 20070101
-
JNK1 contributes to metabotropic glutamate receptor-dependent long-term depression and short-term synaptic plasticity in the mice area hippocampal CA1.
The European journal of neuroscience 20070101
-
Polyphenols downregulate PAI-1 gene expression in cultured human coronary artery endothelial cells: molecular contributor to cardiovascular protection.
Thrombosis research 20070101
-
Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis.
Journal of vascular research 20070101
-
c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.
BMC cell biology 20070101
-
The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
-
UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures.
BMC plant biology 20070101
-
Ca2+ stimulates COX-2 expression through calcium-sensing receptor in fibroblasts.
Biochemical and biophysical research communications 20061229
-
Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes.
Cancer letters 20061208
-
Involvement of MAP kinases in lipopolysaccharide-induced histamine production in RAW 264 cells.
Life sciences 20061203
-
Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis.
Cell death and differentiation 20061201
-
Involvement of p38 MAP kinase and Smad3 in TGF-beta-mediated mast cell functions.
Cellular signalling 20061201
-
Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
Journal of cellular physiology 20061201
-
The c-Jun-N-terminal-Kinase inhibitor SP600125 enhances the butyrate derivative D1-induced apoptosis via caspase 8 activation in Kasumi 1 t(8;21) acute myeloid leukaemia cells.
British journal of haematology 20061201
-
Activation-induced cell death of human melanoma specific cytotoxic T lymphocytes is mediated by apoptosis-inducing factor.
European journal of immunology 20061201
-
JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation.
Hepatology (Baltimore, Md.) 20061201
-
Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.
Cancer research 20061201
-
Interleukin-1beta up-regulates inducible nitric oxide by way of phosphoinositide 3-kinase-dependent in a cochlear cell model.
The Laryngoscope 20061201
-
In vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine production.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20061201
-
[Amelioration of insulin resistance after scald by c-Jun N-terminal kinase inhibitor in rat].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20061201
-
[The role of MAPK/ERK1/2 signaling pathway in aldosterone stimulated transforming growth factor-beta1 synthesis in renal tubular epithelial cells].
Zhonghua yi xue za zhi 20061128
-
Emodin inhibits TNF alpha-induced MMP-1 expression through suppression of activator protein-1 (AP-1).
Life sciences 20061125
-
Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes.
Toxicology and applied pharmacology 20061115
-
Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis.
Oncogene 20061109
-
Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
Carcinogenesis 20061101
-
Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells.
The Journal of pharmacology and experimental therapeutics 20061101
-
Activation of mitogen-activated protein kinases is essential for hydrogen peroxide -induced apoptosis in retinal pigment epithelial cells.
Apoptosis : an international journal on programmed cell death 20061101
-
Histamine differentially interacts with tumor necrosis factor-alpha and thrombin in endothelial tissue factor induction: the role of c-Jun NH2-terminal kinase.
Journal of thrombosis and haemostasis : JTH 20061101
-
P38 MAPK protects against TNF-alpha-provoked apoptosis in LNCaP prostatic cancer cells.
Apoptosis : an international journal on programmed cell death 20061101
-
Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.
Development (Cambridge, England) 20061101
-
Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model.
Journal of immunology (Baltimore, Md. : 1950) 20061101
-
Diabetes-induced mechanical hyperalgesia involves spinal mitogen-activated protein kinase activation in neurons and microglia via N-methyl-D-aspartate-dependent mechanisms.
Molecular pharmacology 20061001
-
Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma.
Leukemia 20061001
-
Regulation by Jun N-terminal kinase/stress activated protein kinase of cytokine expression in Mycobacterium avium subsp paratuberculosis-infected bovine monocytes.
American journal of veterinary research 20061001
-
Transcriptional regulation of the human Sia-alpha2,3-Gal-beta1,4-GlcNAc-R:alpha2,8-sialyltransferase (hST8Sia III) by retinoic acid in human glioblastoma tumor cell line.
Biochimica et biophysica acta 20061001
-
Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers.
Cancer letters 20060928
-
Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation.
The Journal of surgical research 20060901
-
Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.
The Journal of clinical endocrinology and metabolism 20060901
-
p38 MAPK downregulates phosphorylation of Bad in doxorubicin-induced endothelial apoptosis.
Biochemical and biophysical research communications 20060901
-
Growth suppression of human mast cells expressing constitutively active c-kit receptors by JNK inhibitor SP600125.
Genes to cells : devoted to molecular & cellular mechanisms 20060901
-
PPARgamma phosphorylation mediated by JNK MAPK: a potential role in macrophage-derived foam cell formation.
Acta pharmacologica Sinica 20060901
-
Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products.
Arthritis and rheumatism 20060901
-
SP600125, a selective JNK inhibitor, aggravates hepatic ischemia-reperfusion injury.
Experimental & molecular medicine 20060831
-
Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death.
Experimental & molecular medicine 20060831
-
Acquired tolerance in cadmium-adapted lung epithelial cells: roles of the c-Jun N-terminal kinase signaling pathway and basal level of metallothionein.
Toxicology and applied pharmacology 20060815
-
atRA-induced apoptosis of mouse embryonic palate mesenchymal cells involves activation of MAPK pathway.
Toxicology and applied pharmacology 20060815
-
TNFalpha and GM-CSF-induced activation of the CAEV promoter is independent of AP-1.
Virology 20060815
-
Ligustilide inhibits vascular smooth muscle cells proliferation.
European journal of pharmacology 20060807
-
Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein.
Toxicology and applied pharmacology 20060801
-
Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema.
The Journal of pharmacology and experimental therapeutics 20060801
-
Copper-induced stimulation of extracellular signal-regulated kinase in trout hepatocytes: the role of reactive oxygen species, Ca2+, and cell energetics and the impact of extracellular signal-regulated kinase signaling on apoptosis and necrosis.
Toxicological sciences : an official journal of the Society of Toxicology 20060801
-
Low concentrations of paraquat induces early activation of extracellular signal-regulated kinase 1/2, protein kinase B, and c-Jun N-terminal kinase 1/2 pathways: role of c-Jun N-terminal kinase in paraquat-induced cell death.
Toxicological sciences : an official journal of the Society of Toxicology 20060801
-
Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes.
Apoptosis : an international journal on programmed cell death 20060801
-
c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa.
Free radical biology & medicine 20060801
-
Prostaglandin D2 induces the phosphorylation of HSP27 in osteoblasts: function of the MAP kinase superfamily.
Prostaglandins, leukotrienes, and essential fatty acids 20060801
-
c-Jun N-terminal kinase negatively regulates dsRNA and RSV induction of tumor necrosis factor- alpha transcription in human epithelial cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20060801
-
p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.
Brain research 20060712
-
Manganese modulates pro-inflammatory gene expression in activated glia.
Neurochemistry international 20060701
-
Nuclear factor-kappa B-independent anti-inflammatory action of salicylate in human endothelial cells: induction of heme oxygenase-1 by the c-jun N-terminal kinase/activator protein-1 pathway.
The Journal of pharmacology and experimental therapeutics 20060701
-
Essential role of c-Jun-NH2-terminal kinase on synergy induction of apoptosis by TRAIL plus ADM in ADM resistant MCF-7/ADM cells.
Apoptosis : an international journal on programmed cell death 20060701
-
Perfusion-culture-based secreted bioluminescence reporter assay in living cells.
Analytical biochemistry 20060701
-
Map kinase c-JUN N-terminal kinase mediates PMMA induction of osteoclasts.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20060701
-
c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.
Gastroenterology 20060701
-
Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
The Journal of biological chemistry 20060630
-
Ionizing radiation induces apoptosis and inhibits neuronal differentiation in rat neural stem cells via the c-Jun NH2-terminal kinase (JNK) pathway.
Oncogene 20060622
-
Synaptogenesis regulates axotomy-induced activation of c-Jun-activator protein-1 transcription.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060614
-
Mitogen-activated protein kinases mediate arsenic-induced down-regulation of survivin in human lung adenocarcinoma cells.
Archives of toxicology 20060601
-
JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages.
International immunopharmacology 20060601
-
Interplay between epidermal growth factor receptor and Janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells.
Molecular cancer research : MCR 20060601
-
Dracorhodin perchlorate induces apoptosis in HL-60 cells.
Journal of Asian natural products research 20060601
-
Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis.
Brain research 20060530
-
Two distinct steps of Bak regulation during apoptotic stress signaling: different roles of MEKK1 and JNK1.
Experimental cell research 20060515
-
Regression of aortic aneurysms through pharmacologic therapy?
The New England journal of medicine 20060511
-
Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury.
Neuroscience letters 20060508
-
N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells.
Oncogene 20060504
-
Oxidative stress and mitogen-activated protein kinase phosphorylation mediate ammonia-induced cell swelling and glutamate uptake inhibition in cultured astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503
-
Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.
Carcinogenesis 20060501
-
Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases.
Journal of hepatology 20060501
-
Zn2+-induced IL-8 expression involves AP-1, JNK, and ERK activities in human airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 20060501
-
Manganese induces inducible nitric oxide synthase (iNOS) expression via activation of both MAP kinase and PI3K/Akt pathways in BV2 microglial cells.
Neuroscience letters 20060501
-
Iron released by sodium nitroprusside contributes to heme oxygenase-1 induction via the cAMP-protein kinase A-mitogen-activated protein kinase pathway in RAW 264.7 cells.
Molecular pharmacology 20060501
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
Roles for phosphoinositide 3-kinases, Bruton's tyrosine kinase, and Jun kinases in B lymphocyte chemotaxis and homing.
European journal of immunology 20060501
-
The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis.
Immunology 20060501
-
MAP kinase regulation of IP10/CXCL10 chemokine gene expression in microglial cells.
Brain research 20060501
-
The novel antioxidant 3-O-caffeoyl-1-methylquinic acid induces Nrf2-dependent phase II detoxifying genes and alters intracellular glutathione redox.
Free radical biology & medicine 20060415
-
The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
International journal of oncology 20060401
-
Involvement of protein kinases on the upregulation of endothelin receptors in rat basilar and mesenteric arteries.
Experimental biology and medicine (Maywood, N.J.) 20060401
-
Differential involvement of nuclear factor-kappaB and activator protein-1 pathways in the interleukin-1beta-mediated decrease of deiodinase type 1 and thyroid hormone receptor beta1 mRNA.
The Journal of endocrinology 20060401
-
S-adenosyl-methionine decreases ethanol-induced apoptosis in primary hepatocyte cultures by a c-Jun N-terminal kinase activity-independent mechanism.
World journal of gastroenterology 20060328
-
Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species.
Journal of cell science 20060315
-
Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.
Molecular and cellular endocrinology 20060309
-
Interleukin-1 beta up-regulates tissue inhibitor of matrix metalloproteinase-1 mRNA and phosphorylation of c-jun N-terminal kinase and p38 in hepatic stellate cells.
World journal of gastroenterology 20060307
-
Resveratrol protects against 4-hydroxynonenal-induced apoptosis by blocking JNK and c-JUN/AP-1 signaling.
Toxicological sciences : an official journal of the Society of Toxicology 20060301
-
Opposing effect of p38 MAP kinase and JNK inhibitors on the development of heart failure in the cardiomyopathic hamster.
Cardiovascular research 20060301
-
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
-
Pro-inflammatory signaling by Jun-N-terminal kinase in inflammatory bowel disease.
International journal of molecular medicine 20060301
-
Selective pharmacologic inhibition of c-Jun NH2-terminal kinase radiosensitizes thyroid anaplastic cancer cell lines via induction of terminal growth arrest.
Thyroid : official journal of the American Thyroid Association 20060301
-
FADD phosphorylation is critical for cell cycle regulation in breast cancer cells.
British journal of cancer 20060227
-
Inhibition of apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling.
Biochemistry 20060221
-
Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.
Cardiovascular research 20060215
-
As2O3-induced c-Src/EGFR/ERK signaling is via Sp1 binding sites to stimulate p21WAF1/CIP1 expression in human epidermoid carcinoma A431 cells.
Cellular signalling 20060201
-
A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.
Journal of lipid research 20060201
-
Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line.
Journal of leukocyte biology 20060201
-
Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells.
Cardiovascular research 20060201
-
The roles of Akt and MAPK family members in silymarin's protection against UV-induced A375-S2 cell apoptosis.
International immunopharmacology 20060201
-
Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathways.
Journal of periodontal research 20060201
-
Transcriptional repression of telomerase RNA gene expression by c-Jun-NH2-kinase and Sp1/Sp3.
Cancer research 20060201
-
c-Jun N-terminal kinase contributes to norepinephrine-induced contraction through phosphorylation of caldesmon in rat aortic smooth muscle.
Journal of pharmacological sciences 20060201
-
Brain ischemia/reperfusion-induced expression of DP5 and its interaction with Bcl-2, thus freeing Bax from Bcl-2/Bax dimmers are mediated by c-Jun N-terminal kinase (JNK) pathway.
Neuroscience letters 20060130
-
Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.
FEBS letters 20060123
-
NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation.
Biochemical and biophysical research communications 20060106
-
Opposite effect of ERK1/2 and JNK on p53-independent p21WAF1/CIP1 activation involved in the arsenic trioxide-induced human epidermoid carcinoma A431 cellular cytotoxicity.
Journal of biomedical science 20060101
-
c-Jun NH2-terminal kinase mediates interleukin-1beta-induced inhibition of lacrimal gland secretion.
Journal of neurochemistry 20060101
-
c-Jun N-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production.
Journal of neuroscience research 20060101
-
Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal.
Free radical biology & medicine 20060101
-
NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription.
Journal of immunology (Baltimore, Md. : 1950) 20060101
-
Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA.
Cellular microbiology 20060101
-
Activation of c-Jun N-terminal kinase (JNK) signalling in experimentally induced gastric lesions in rats.
Clinical and experimental immunology 20060101
-
Thermal injury-induced peroxynitrite production and pulmonary inducible nitric oxide synthase expression depend on JNK/AP-1 signaling.
Critical care medicine 20060101
-
[Effects of sp600125 on proliferation and protein expression of bcl-2 and c-myc in hepatic stellate cells].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060101
-
Trimidox induces apoptosis via cytochrome c release in NALM-6 human B cell leukaemia cells.
Basic & clinical pharmacology & toxicology 20060101
-
Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: implication in inducible nitric oxide synthase expression.
BMC pharmacology 20060101
-
Inhibition of UVA-induced c-Jun N-terminal kinase activity results in caspase-dependent apoptosis in human keratinocytes.
Photochemistry and photobiology 20060101
-
C-Jun N-terminal kinase (JNK) regulation of iNOS expression in glial cells: predominant role of JNK1 isoform.
Antioxidants & redox signaling 20060101
-
Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells.
Respiratory research 20060101
-
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Arthritis research & therapy 20060101
-
JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages.
Mediators of inflammation 20060101
-
Up-regulation of P-glycoprotein expression by catalase via JNK activation in HepG2 cells.
Redox report : communications in free radical research 20060101
-
Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis.
Cancer research 20051215
-
Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway.
Cellular signalling 20051201
-
Gaseous nitrogen oxide repressed benzo[a]pyrene-induced human lung fibroblast cell apoptosis via inhibiting JNK1 signals.
Archives of toxicology 20051201
-
Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression.
American journal of physiology. Gastrointestinal and liver physiology 20051201
-
KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells.
Journal of lipid research 20051201
-
Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase.
Nature medicine 20051201
-
Aneurysm treatments expand.
Nature medicine 20051201
-
X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1).
The Journal of biological chemistry 20051118
-
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation.
The Journal of biological chemistry 20051118
-
Arsenite enhances tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1.
Toxicology and applied pharmacology 20051115
-
The role of p38 MAP kinase and c-Jun N-terminal protein kinase signaling in the differentiation and apoptosis of immortalized neural stem cells.
Mutation research 20051111
-
Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation.
Leukemia 20051101
-
Regulation of B7.1 costimulatory molecule is mediated by the IFN regulatory factor-7 through the activation of JNK in lipopolysaccharide-stimulated human monocytic cells.
Journal of immunology (Baltimore, Md. : 1950) 20051101
-
Agents targeting c-Jun N-terminal kinase pathway as potential neuroprotectants.
Expert opinion on investigational drugs 20051101
-
[Role of MAPK in the migration of human coronary artery smooth muscle cell into three-dimensional fibrin gel].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20051101
-
Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes.
Mediators of inflammation 20051024
-
The role of p-c-Jun in survival and outgrowth of developing sensory neurons.
Neuroreport 20051017
-
Arsenic trioxide induces Hsp70 expression via reactive oxygen species and JNK pathway in MDA231 cells.
Life sciences 20051014
-
Regulation of cAMP-induced arylalkylamine N-acetyltransferase, Period1, and MKP-1 gene expression by mitogen-activated protein kinases in the rat pineal gland.
Brain research. Molecular brain research 20051003
-
Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.
European journal of pharmacology 20051003
-
Effects of the JNK inhibitor anthra[1,9-cd]pyrazol-6(2H)-one (SP-600125) on soluble guanylyl cyclase alpha1 gene regulation and cGMP synthesis.
American journal of physiology. Cell physiology 20051001
-
Phosphorylation of the retinoid x receptor at the omega loop, modulates the expression of retinoic-acid-target genes with a promoter context specificity.
Cellular signalling 20051001
-
Conditional expression of MAP kinase phosphatase-2 protects against genotoxic stress-induced apoptosis by binding and selective dephosphorylation of nuclear activated c-jun N-terminal kinase.
Cellular signalling 20051001
-
Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells.
Arteriosclerosis, thrombosis, and vascular biology 20051001
-
Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite.
Molecular and cellular biology 20051001
-
JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
Cellular and molecular life sciences : CMLS 20051001
-
Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation.
The Journal of clinical investigation 20051001
-
Mitomycin-C induces the apoptosis of human Tenon's capsule fibroblast by activation of c-Jun N-terminal kinase 1 and caspase-3 protease.
Investigative ophthalmology & visual science 20051001
-
Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
The Journal of biological chemistry 20050923
-
c-Jun N-terminal kinase activation in dorsal root ganglion contributes to pain hypersensitivity.
Biochemical and biophysical research communications 20050916
-
Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation.
Molecular biology of the cell 20050901
-
Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells.
Journal of toxicology and environmental health. Part A 20050901
-
Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.
Cell cycle (Georgetown, Tex.) 20050901
-
Ablation of the spindle assembly checkpoint by a compound targeting Mps1.
EMBO reports 20050901
-
Inhibition of inflammatory bone erosion by constitutively active STAT-6 through blockade of JNK and NF-kappaB activation.
Arthritis and rheumatism 20050901
-
Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB.
American journal of respiratory cell and molecular biology 20050801
-
Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling.
Bone 20050801
-
HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells.
Free radical biology & medicine 20050801
-
Multiple anti-apoptotic pathways stimulated by EGF in cytotrophoblasts.
Placenta 20050801
-
Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism.
Journal of neurochemistry 20050801
-
Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest.
Cancer research 20050801
-
Mitogen-activated protein kinases (MAPKs) mediate SIN-1/ glucose deprivation-induced death in rat primary astrocytes.
Archives of pharmacal research 20050801
-
Histamine induces tissue factor expression: implications for acute coronary syndromes.
Circulation 20050719
-
Eosinophil migration induced by mast cell chymase is mediated by extracellular signal-regulated kinase pathway.
Biochemical and biophysical research communications 20050715
-
Radical mediators and mitogen-activated protein kinase signaling in oxygen-dependent radiosensitivity of human tumor cell lines.
Free radical biology & medicine 20050715
-
Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
Cancer research 20050715
-
Cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells through activation of the proapoptotic Bcl-2 family proteins and MAPK pathway.
Life sciences 20050708
-
P-glycoprotein-independent apoptosis induction by a novel synthetic compound, MMPT [5-[(4-methylphenyl)methylene]-2-(phenylamino)-4(5H)-thiazolone].
The Journal of pharmacology and experimental therapeutics 20050701
-
Investigating the neuroprotective mechanism of action of a CDK5 inhibitor by phosphoproteome analysis.
Journal of cellular biochemistry 20050701
-
CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway.
Experimental cell research 20050701
-
Polypeptide from Chlamys farreri inhibits murine thymocytes apoptosis and modulates UVB induced signaling pathway activation.
Life sciences 20050701
-
Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage.
Stroke 20050701
-
Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection.
Current eye research 20050701
-
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.
The Journal of biological chemistry 20050617
-
Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors.
Archives of biochemistry and biophysics 20050615
-
Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells.
Toxicology and applied pharmacology 20050615
-
Inhibition of the PI3K pathway sensitizes fludarabine-induced apoptosis in human leukemic cells through an inactivation of MAPK-dependent pathway.
Biochemical and biophysical research communications 20050603
-
c-Jun NH2-terminal kinase mediation of angiotensin II-induced proliferation of human mesangial cells.
American journal of physiology. Renal physiology 20050601
-
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050601
-
Short-term interleukin-1(beta) increases the release of secreted APP(alpha) via MEK1/2-dependent and JNK-dependent alpha-secretase cleavage in neuroglioma U251 cells.
Journal of neuroscience research 20050601
-
DNA topoisomerase I is a cofactor for c-Jun in the regulation of epidermal growth factor receptor expression and cancer cell proliferation.
Molecular and cellular biology 20050601
-
Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells.
The Journal of endocrinology 20050601
-
Inflammatory pathway analysis using a high content screening platform.
Assay and drug development technologies 20050601
-
Activation of c-Jun N-terminal kinase is required for neurite outgrowth of dopaminergic neuronal cells.
Neuroreport 20050531
-
2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process.
Oncogene 20050526
-
Contribution of mitogen-activated protein kinases to NMDA-induced neurotoxicity in the rat retina.
Brain research 20050524
-
Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8.
The Journal of biological chemistry 20050513
-
Keratinocyte growth factor expression by fibroblasts in pulmonary fibrosis: poor response to interleukin-1beta.
American journal of respiratory cell and molecular biology 20050501
-
Inhibition of c-Jun N-terminal kinase limits lipopolysaccharide-induced pulmonary neutrophil influx.
American journal of respiratory and critical care medicine 20050501
-
Juzentaihoto, a Kampo medicine, enhances IL-12 production by modulating Toll-like receptor 4 signaling pathways in murine peritoneal exudate macrophages.
International immunopharmacology 20050501
-
Pepsin-digested bovine lactoferrin induces apoptotic cell death with JNK/SAPK activation in oral cancer cells.
Journal of pharmacological sciences 20050501
-
c-Jun NH2-terminal kinase-interacting protein-3 facilitates phosphorylation and controls localization of amyloid-beta precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413
-
Requirement for ERK activation in acetone extract identified from Bupleurum scorzonerifolium induced A549 tumor cell apoptosis and keratin 8 phosphorylation.
Life sciences 20050408
-
Inhibition of tumor growth, angiogenesis, and tumor cell proliferation by a small molecule inhibitor of c-Jun N-terminal kinase.
The Journal of pharmacology and experimental therapeutics 20050401
-
Leptin induces hypertrophy via p38 mitogen-activated protein kinase in rat vascular smooth muscle cells.
Biochemical and biophysical research communications 20050401
-
Cigarette smoke extract induces endothelial cell injury via JNK pathway.
Biochemical and biophysical research communications 20050401
-
Jun N-terminal kinase is essential for CD40-mediated IgE class switching in B cells.
The Journal of allergy and clinical immunology 20050401
-
Retinoic acid and arsenic trioxide cooperate for apoptosis through phosphorylated RXR alpha.
Oncogene 20050331
-
Activation of c-Jun NH2-terminal kinase (JNK) signaling pathway is essential for the stimulation of hepatitis C virus (HCV) non-structural protein 3 (NS3)-mediated cell growth.
Virology 20050315
-
A small molecule-kinase interaction map for clinical kinase inhibitors.
Nature biotechnology 20050301
-
Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
Molecular cancer therapeutics 20050301
-
SAPK/JNK plays a role in transforming growth factor-beta-induced VEGF synthesis in osteoblasts.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050301
-
The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways.
Brain research 20050221
-
Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
-
Cypermethrin blocks a mitochondria-dependent apoptotic signal initiated by deficient N-linked glycosylation within the endoplasmic reticulum.
Cellular signalling 20050201
-
Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line.
Cellular signalling 20050201
-
Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways.
Arteriosclerosis, thrombosis, and vascular biology 20050201
-
c-Jun N-terminal kinase is involved in mercuric ions-mediated interleukin-4 secretion in mast cells.
International archives of allergy and immunology 20050201
-
Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes.
European journal of pharmacology 20050131
-
Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes.
Toxicology 20050115
-
Implication of the MAPK pathways in the maturation of human dendritic cells induced by nickel and TNF-alpha.
Toxicology 20050115
-
Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase.
Biochemical and biophysical research communications 20050114
-
Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: effects of SP600125.
European journal of pharmacology 20050104
-
Synthesis of the Na-K-ATPase gamma-subunit is regulated at both the transcriptional and translational levels in IMCD3 cells.
American journal of physiology. Renal physiology 20050101
-
Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells.
Hypertension (Dallas, Tex. : 1979) 20050101
-
Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK.
Neurobiology of aging 20050101
-
Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis.
Gastroenterology 20050101
-
Interleukin-1beta-induced transdifferentiation of renal proximal tubular cells is mediated by activation of JNK and p38 MAPK.
Nephron. Experimental nephrology 20050101
-
Differential involvement of p38 and JNK MAP kinases in HIV-1 Tat and gp120-induced apoptosis and neurite degeneration in striatal neurons.
Neuroscience 20050101
-
Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.
Respiratory research 20050101
-
JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine.
The Journal of biological chemistry 20041231
-
Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells.
Experimental & molecular medicine 20041231
-
Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages.
Free radical biology & medicine 20041215
-
p38alpha, but not p38beta, inhibits the phosphorylation and presence of c-FLIPS in DISC to potentiate Fas-mediated caspase-8 activation and type I apoptotic signaling.
Journal of cell science 20041215
-
c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia.
Cancer research 20041215
-
Lipopolysaccharide stimulates nitric oxide synthase-2 expression in murine skeletal muscle and C(2)C(12) myoblasts via Toll-like receptor-4 and c-Jun NH(2)-terminal kinase pathways.
American journal of physiology. Cell physiology 20041201
-
Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells.
International immunology 20041201
-
Methotrexate enhances prostaglandin D2-stimulated heat shock protein 27 induction in osteoblasts.
Prostaglandins, leukotrienes, and essential fatty acids 20041201
-
Induction of serine racemase by inflammatory stimuli is dependent on AP-1.
Annals of the New York Academy of Sciences 20041201
-
Microtubule disarray in primary cultures of human hepatocytes inhibits transcriptional activity of the glucocorticoid receptor via activation of c-jun N-terminal kinase.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20041201
-
KR-31378 protects cardiac H9c2 cells from chemical hypoxia-induced cell death via inhibition of JNK/p38 MAPK activation.
The Japanese journal of physiology 20041201
-
c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK).
Oncogene 20041125
-
Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress.
Molecular cell 20041119
-
UV-induced apoptosis in SH-SY5Y cells: contribution to apoptosis by JNK signaling and cytochrome c.
Journal of neuroscience research 20041115
-
Rescuing melanoma epitope-specific cytolytic T lymphocytes from activation-induced cell death, by SP600125, an inhibitor of JNK: implications in cancer immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 20041115
-
Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Circulation research 20041112
-
Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
-
Transforming growth factor-beta induces the expression of ANF and hypertrophic growth in cultured cardiomyoblast cells through ZAK.
Biochemical and biophysical research communications 20041105
-
Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways.
Brain research. Molecular brain research 20041104
-
Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
Carcinogenesis 20041101
-
Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons.
Molecular and cellular neurosciences 20041101
-
Possible pathophysiological roles of mitogen-activated protein kinases (MAPKs) in endometriosis.
American journal of reproductive immunology (New York, N.Y. : 1989) 20041101
-
Protective effects of SP600125 a new inhibitor of c-jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis.
Life sciences 20041029
-
Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin.
Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
-
Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.
Journal of applied physiology (Bethesda, Md. : 1985) 20041001
-
Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets.
Endocrinology 20041001
-
Calcium-mediated activation of c-Jun NH2-terminal kinase (JNK) and apoptosis in response to cadmium in murine macrophages.
Toxicological sciences : an official journal of the Society of Toxicology 20041001
-
MAP kinases differentially regulate the expression of macrophage hyperactivity after thermal injury.
Journal of cellular physiology 20041001
-
Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells.
Journal of biomechanics 20041001
-
High sensitivity of fibroblast cell lines derived from LEC rats to heat treatment.
The Journal of veterinary medical science 20041001
-
Anti-apoptotic and pro-apoptotic effect of NEPP11 on manganese-induced apoptosis and JNK pathway activation in PC12 cells.
Brain research 20040924
-
Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration.
European journal of pharmacology 20040913
-
Regulation of tumor necrosis factor-alpha in glioma cells by lead and lipopolysaccharide: involvement of common signaling pathway.
Toxicology letters 20040910
-
Indirubin-3'-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons.
Neuroscience letters 20040909
-
The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
-
Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection.
Circulation 20040907
-
Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages.
The Journal of general virology 20040901
-
Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships.
Molecular pharmacology 20040901
-
Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
Circulation research 20040820
-
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation.
The Journal of clinical investigation 20040816
-
p21(Cip-1/SDI-1/WAF-1) expression via the mitogen-activated protein kinase signaling pathway in insulin-induced chondrogenic differentiation of ATDC5 cells.
Biochemical and biophysical research communications 20040806
-
A c-Jun NH2-terminal kinase inhibitor SP600125 (anthra[1,9-cd]pyrazole-6 (2H)-one) blocks activation of pancreatic stellate cells.
The Journal of pharmacology and experimental therapeutics 20040801
-
Jun N-terminal kinase promotes proliferation of immature erythroid cells and erythropoietin-dependent cell lines.
Blood 20040801
-
JNK MAP kinase is involved in the humoral immune response of the greater wax moth larvae Galleria mellonella.
Archives of insect biochemistry and physiology 20040801
-
Interleukin-4 increases murine airway response to kinins, via up-regulation of bradykinin B1-receptors and altered signalling along mitogen-activated protein kinase pathways.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040801
-
The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway.
The Journal of biological chemistry 20040730
-
Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.
The Journal of biological chemistry 20040716
-
Induction of matrix metalloproteinase-2 by tenascin-X deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase phosphorylation pathway.
Experimental cell research 20040715
-
Mood stabilizers inhibit glucocorticoid receptor function in LMCAT cells.
European journal of pharmacology 20040714
-
JNK signaling involved in the effects of cyclic AMP on IL-1beta plus IFNgamma-induced inducible nitric oxide synthase expression in hepatocytes.
Cellular signalling 20040701
-
Amphetamine activates connexin43 gene expression in cultured neonatal rat cardiomyocytes through JNK and AP-1 pathway.
Cardiovascular research 20040701
-
Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats.
Immunology 20040701
-
C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression.
Drug metabolism and disposition: the biological fate of chemicals 20040701
-
Macrophage-mediated renal injury is dependent on signaling via the JNK pathway.
Journal of the American Society of Nephrology : JASN 20040701
-
Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin.
Molecular cancer therapeutics 20040701
-
Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner.
Circulation research 20040611
-
Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells.
Oncogene 20040603
-
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.
The EMBO journal 20040602
-
BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists.
The EMBO journal 20040602
-
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
Journal of the American Society of Nephrology : JASN 20040601
-
Involvement of SAPK/JNK in prostaglandin E(1)-induced VEGF synthesis in osteoblast-like cells.
Molecular and cellular endocrinology 20040531
-
Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway.
The Journal of biological chemistry 20040521
-
Involvement of stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK) in prostaglandin F2alpha-induced heat shock protein 27 in osteoblasts.
Prostaglandins, leukotrienes, and essential fatty acids 20040501
-
The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
Experimental cell research 20040501
-
Anti-apoptotic effects of curcumin on photosensitized human epidermal carcinoma A431 cells.
Journal of cellular biochemistry 20040501
-
Dimethylaminopurine inhibits metabolic effects of insulin in primary adipocytes.
The Journal of nutritional biochemistry 20040501
-
Involvement of ROS and JNK1 in selenite-induced apoptosis in Chang liver cells.
Experimental & molecular medicine 20040430
-
JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells.
The Journal of biological chemistry 20040423
-
Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells.
Toxicology and applied pharmacology 20040415
-
Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040401
-
The role of c-Jun N-terminal kinase in the A beta-mediated impairment of LTP and regulation of synaptic transmission in the hippocampus.
Neuropharmacology 20040401
-
MAPK signaling pathways modulate IL-1beta expression in human keratinocytes.
Archives of biochemistry and biophysics 20040401
-
Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells.
Journal of cellular biochemistry 20040401
-
Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cells via extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase activation.
Molecular pharmacology 20040401
-
Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040331
-
Lipopolysaccharide-induced c-Jun NH2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-Kinase and Syk-mediated pathways.
The Journal of biological chemistry 20040319
-
Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent.
The Journal of biological chemistry 20040319
-
Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential.
Biochimica et biophysica acta 20040311
-
Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways.
The Journal of biological chemistry 20040305
-
Reciprocal regulation of beta-adrenergic receptor mRNA stability by mitogen activated protein kinase activation and inhibition.
Molecular and cellular biochemistry 20040301
-
Thombospondin-1 disrupts estrogen-induced endothelial cell proliferation and migration and its expression is suppressed by estradiol.
Molecular cancer research : MCR 20040301
-
Ventilation-induced neutrophil infiltration depends on c-Jun N-terminal kinase.
American journal of respiratory and critical care medicine 20040215
-
Bcl-2 enhances neurite extension via activation of c-Jun N-terminal kinase.
Biochemical and biophysical research communications 20040206
-
Sphingomyelinase of Helicobacter pylori-induced cytotoxicity in AGS gastric epithelial cells via activation of JNK kinase.
Biochemical and biophysical research communications 20040206
-
c-Jun is regulated by combination of enhanced expression and phosphorylation in acute-overloaded rat heart.
American journal of physiology. Heart and circulatory physiology 20040201
-
DEP-induced fra-1 expression correlates with a distinct activation of AP-1-dependent gene transcription in the lung.
American journal of physiology. Lung cellular and molecular physiology 20040201
-
SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease.
Neuroscience research 20040201
-
Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells.
Molecular cancer research : MCR 20040201
-
12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.
The Journal of biological chemistry 20040130
-
All-trans retinoic acid potentiates Taxotere-induced cell death mediated by Jun N-terminal kinase in breast cancer cells.
Oncogene 20040115
-
Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell death.
European journal of pharmacology 20040112
-
An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase.
The Journal of biological chemistry 20040109
-
Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040107
-
Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1.
The Journal of biological chemistry 20040102
-
Opposed arsenite-induced signaling pathways promote cell proliferation or apoptosis in cultured lung cells.
Carcinogenesis 20040101
-
Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms.
Carcinogenesis 20040101
-
Retinoblastoma protein and CCAAT/enhancer-binding protein beta are required for 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL60 cells.
Cancer research 20040101
-
Erianin induces a JNK/SAPK-dependent metabolic inhibition in human umbilical vein endothelial cells.
In vivo (Athens, Greece) 20040101
-
Characterization of Cd-induced molecular events prior to cellular damage in primary rat hepatocytes in culture: activation of the stress activated signal protein JNK and transcription factor AP-1.
Journal of biochemical and molecular toxicology 20040101
-
Inhibition of c-Jun NH2-terminal kinase or extracellular signal-regulated kinase improves lung injury.
Respiratory research 20040101
-
p38 MAP kinase mediates bilirubin-induced neuronal death of cultured rat cerebellar granule neurons.
Neuroscience letters 20031226
-
IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase.
Cellular signalling 20031201
-
Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.
British journal of pharmacology 20031201
-
Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase.
British journal of pharmacology 20031201
-
Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin).
Toxicology and applied pharmacology 20031201
-
N-nitrosocarbofuran induces apoptosis in mouse brain microvascular endothelial cells (bEnd.3).
Journal of pharmacological sciences 20031201
-
Biologic sequelae of c-Jun NH(2)-terminal kinase (JNK) activation in multiple myeloma cell lines.
Oncogene 20031127
-
Inhibition of JNK signaling diminishes early but not late cellular stress-induced apoptosis.
International journal of cancer 20031120
-
Inhibition by dexamethasone of interleukin 13 production via glucocorticoid receptor-mediated inhibition of c-Jun phosphorylation.
FEBS letters 20031120
-
C-jun N-terminal kinase (JNK) inhibitor, SP600125, blocks interleukin (IL)-6-induced vascular endothelial growth factor (VEGF) production: cyclosporine A partially mimics this inhibitory effect.
Transplantation 20031115
-
Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.
Cytokine 20031107
-
Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH2-terminal kinase.
American journal of physiology. Regulatory, integrative and comparative physiology 20031101
-
The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor.
Drug metabolism and disposition: the biological fate of chemicals 20031101
-
Mitogen activated protein kinases selectively regulate palytoxin-stimulated gene expression in mouse keratinocytes.
Toxicology and applied pharmacology 20031101
-
Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20031101
-
Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes.
The Journal of biological chemistry 20031010
-
Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis.
Neuropharmacology 20031001
-
Involvement of the JNK-like protein of the Aedes albopictus mosquito cell line, C6/36, in phagocytosis, endocytosis and infection of West Nile virus.
Insect molecular biology 20031001
-
Inhibition of the SAPK/JNK pathway blocks the stimulatory effects of glutamine on fluid secretion by the Malpighian tubules of Rhodnius prolixus.
Journal of insect physiology 20031001
-
The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.
The Journal of pharmacology and experimental therapeutics 20030901
-
Involvement of stress-activated protein kinase/c-Jun N-terminal kinase in endothelin-1-induced heat shock protein 27 in osteoblasts.
European journal of endocrinology 20030901
-
Sphingosine-1-phosphate-induced ERK activation protects human melanocytes from UVB-induced apoptosis.
Archives of pharmacal research 20030901
-
The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration.
The EMBO journal 20030815
-
SP600125, an inhibitor of c-jun N-terminal kinase, activates CREB by a p38 MAPK-mediated pathway.
Biochemical and biophysical research communications 20030808
-
Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases.
American journal of physiology. Lung cellular and molecular physiology 20030801
-
The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells.
Carcinogenesis 20030801
-
c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages.
Molecular pharmacology 20030801
-
Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-alpha in cultured human umbilical vein endothelial cells.
Cardiovascular research 20030801
-
Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase.
Surgery 20030801
-
The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity.
Chemistry & biology 20030801
-
c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production.
Journal of immunology (Baltimore, Md. : 1950) 20030715
-
c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells.
The Journal of biological chemistry 20030711
-
JNK phosphorylates paxillin and regulates cell migration.
Nature 20030710
-
Ephrin-B1 reverse signaling activates JNK through a novel mechanism that is independent of tyrosine phosphorylation.
The Journal of biological chemistry 20030704
-
Effects of transforming growth factor-[beta] and budesonide on mitogen-activated protein kinase activation and apoptosis in airway epithelial cells.
American journal of respiratory cell and molecular biology 20030701
-
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.
Genes & development 20030701
-
The role of JNK and p38 MAPK activities in UVA-induced signaling pathways leading to AP-1 activation and c-Fos expression.
Neoplasia (New York, N.Y.) 20030701
-
JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents.
The Journal of biological chemistry 20030620
-
The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair.
The Journal of biological chemistry 20030606
-
C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts.
American journal of respiratory cell and molecular biology 20030601
-
Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes.
Hepatology (Baltimore, Md.) 20030601
-
Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes.
The Journal of biological chemistry 20030516
-
JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells.
The Journal of biological chemistry 20030516
-
Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA.
Journal of immunology (Baltimore, Md. : 1950) 20030515
-
Comparison between ischaemic and anisomycin-induced preconditioning: role of p38 MAPK.
Cardiovascular drugs and therapy 20030501
-
The specificities of protein kinase inhibitors: an update.
The Biochemical journal 20030401
-
c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration.
Hepatology (Baltimore, Md.) 20030401
-
Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
Clinical cancer research : an official journal of the American Association for Cancer Research 20030401
-
Involvement of SAPK/JNK in basic fibroblast growth factor-induced vascular endothelial growth factor release in osteoblasts.
The Journal of endocrinology 20030401
-
Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF.
Oncogene 20030327
-
Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation.
The Journal of biological chemistry 20030307
-
Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.
Oncogene 20030306
-
Type 2 deiodinase expression is stimulated by growth factors in human vascular smooth muscle cells.
Molecular and cellular endocrinology 20030227
-
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.
Blood 20030215
-
Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells.
Molecular pharmacology 20030201
-
Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.
Journal of neurochemistry 20030201
-
Inhibition of hippocampal Jun N-terminal kinase enhances short-term memory but blocks long-term memory formation and retrieval of an inhibitory avoidance task.
The European journal of neuroscience 20030201
-
Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
The Journal of biological chemistry 20030103
-
A role for c-Jun N-terminal kinase in the inhibition of long-term potentiation by interleukin-1beta and long-term depression in the rat dentate gyrus in vitro.
Neuroscience 20030101
-
p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth.
Molecular cancer 20030101
-
Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein.
The Biochemical journal 20021115
-
[Synergetic effect of mitogen-activated protein kinase pathway on expression of tumor necrosis factor alpha gene in RAW 264.7 cells induced by lipopolysaccharide].
Zhonghua yi xue za zhi 20021025
-
c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes.
Circulation research 20021004
-
Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase.
Archives of biochemistry and biophysics 20020915
-
An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression.
Biochimica et biophysica acta 20020508
-
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
-
Stress-activated protein kinase/c-Jun N-terminal kinase (JNK) plays a part in endothelin-1-induced vascular endothelial growth factor synthesis in osteoblasts.
Journal of cellular biochemistry 20020101
-
Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571.
Cancer biology & therapy 20020101
-
Role of JNK in hypertonic activation of Cl(-)-dependent Na(+)/H(+) exchange in Xenopus oocytes.
American journal of physiology. Cell physiology 20011201
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase.
Proceedings of the National Academy of Sciences of the United States of America 20011120
-
TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells.
Hepatology (Baltimore, Md.) 20011101
-
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis.
The Journal of clinical investigation 20010701
-
Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation.
Molecular endocrinology (Baltimore, Md.)