13081-18-0 | Ethyl trifluoropyruvate

Packsize	Purity	Availability	Price	Discounted Price
10g	96%	in stock	$6.00	$5.00
25g	96%	in stock	$14.00	$10.00
100g	96%	in stock	$42.00	$30.00

Description

• Catalog Number: AB46140
• Chemical Name: Ethyl trifluoropyruvate
• CAS Number: 13081-18-0
• Molecular Formula: C5H5F3O3
• Molecular Weight: 170.0866
• MDL Number: MFCD00114935
• SMILES: CCOC(=O)C(=O)C(F)(F)F

Computed Properties

• Complexity: 172
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• XLogP3: 1.5

Literature

• Asymmetric synthesis of the carbon-14-labeled selective glucocorticoid receptor modulator using cinchona alkaloid catalyzed addition of 6-bromoindole to ethyl trifluoropyruvate.

  Molecules (Basel, Switzerland) 20120530

• Ethyl 3,3,3-trifluoro-2-hy-droxy-2-(5-meth-oxy-1H-indol-3-yl)propionate.

  Acta crystallographica. Section E, Structure reports online 20110701

• Straightforward synthesis of enantiopure (R)- and (S)-trifluoroalaninol.

  Organic & biomolecular chemistry 20101021

• Joint experimental and DFT study of the gas-phase unimolecular elimination kinetic of methyl trifluoropyruvate.

  The journal of physical chemistry. A 20100805

• Catalytic asymmetric synthesis of 3-(alpha-hydroxy-beta-carbonyl) oxindoles by a Sc(III)-catalyzed direct aldol-type reaction.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100322

• The first organocatalytic carbonyl-ene reaction: isomerisation-free C-C bond formations catalysed by H-bonding thio-ureas.

  Beilstein journal of organic chemistry 20070101

• Cinchona-alkaloid-catalyzed enantioselective direct aldol-type reaction of oxindoles with ethyl trifluoropyruvate.

  Angewandte Chemie (International ed. in English) 20070101

• Asymmetric platinum group metal-catalyzed carbonyl-ene reactions: carbon-carbon bond formation versus isomerization.

  The Journal of organic chemistry 20061222

• Straightforward synthesis of (S)- and (R)-alpha-trifluoromethyl proline from chiral oxazolidines derived from ethyl trifluoropyruvate.

  Organic letters 20061221

• Highly enantioselective organocatalytic hydroxyalkylation of indoles with ethyl trifluoropyruvate.

  Angewandte Chemie (International ed. in English) 20050513

• Regioselectively nucleus and/or side-chain fluorinated 2-(Phenanthryl)propionic acids by an effective combination of radical and organometallic chemistry.

  The Journal of organic chemistry 20050121