1346574-57-9 | Gsk126

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$80.00	$56.00
5mg	95%	in stock	$105.00	$74.00
25mg	95%	in stock	$178.00	$124.00
100mg	95%	in stock	$463.00	$324.00

Description

• Catalog Number: AE35687
• Chemical Name: Gsk126
• CAS Number: 1346574-57-9
• Molecular Formula: C31H38N6O2
• Molecular Weight: 526.6724200000001
• MDL Number: MFCD23381067
• SMILES: CC[C@@H](n1cc(c2c1cc(cc2C(=O)NCc1c(C)cc([nH]c1=O)C)c1ccc(nc1)N1CCNCC1)C)C

Computed Properties

• Complexity: 972
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 39
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 7
• XLogP3: 3.9

Literature

• Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2.

  The Journal of biological chemistry 20151113

• EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.

  Nature 20121206

• Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens.

  Journal of biomolecular screening 20121201