1346704-33-3 | Gsk343

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$32.00	$22.00
5mg	99%	in stock	$56.00	$39.00
10mg	99%	in stock	$90.00	$63.00
25mg	99%	in stock	$162.00	$113.00
50mg	99%	in stock	$313.00	$219.00

Description

• Catalog Number: AE35693
• Chemical Name: Gsk343
• CAS Number: 1346704-33-3
• Molecular Formula: C31H39N7O2
• Molecular Weight: 541.6871
• MDL Number: MFCD25563250
• SMILES: CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2c1cnn2C(C)C)c1ccnc(c1)N1CCN(CC1)C

Computed Properties

• Complexity: 986
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 40
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 4

Literature

• Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

  Nature communications 20140101

• Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition.

  Cell cycle (Georgetown, Tex.) 20130701

• Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2.

  ACS medicinal chemistry letters 20121213