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Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Bioorganic & medicinal chemistry 20121115
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Syntheses of (-)-pelletierine and (-)-homopipecolic acid.
Organic & biomolecular chemistry 20120407
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Structure-activity relationship studies of SYA 013, a homopiperazine analog of haloperidol.
Bioorganic & medicinal chemistry 20120301
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Current pharmacological advances in the treatment of cardiac arrest.
Emergency medicine international 20120101
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Development of a liquid chromatography-tandem mass spectrometric method for the simultaneous determination of tropane alkaloids and glycoalkaloids in crops.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110901
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Elucidation of the mechanism of N-demethylation catalyzed by cytochrome P450 monooxygenase is facilitated by exploiting nitrogen-15 heavy isotope effects.
Archives of biochemistry and biophysics 20110601
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Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud.
Evidence-based complementary and alternative medicine : eCAM 20110101
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Co-expression of AaPMT and AaTRI effectively enhances the yields of tropane alkaloids in Anisodus acutangulus hairy roots.
BMC biotechnology 20110101
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Beneficial effects of anisodamine in shock involved cholinergic anti-inflammatory pathway.
Frontiers in pharmacology 20110101
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Modeling natural anti-inflammatory compounds by molecular topology.
International journal of molecular sciences 20110101
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High-performance liquid-chromatographic tandem-mass spectrometric methods for atropinesterase-mediated enantioselective and chiral determination of R- and S-hyoscyamine in plasma.
Analytica chimica acta 20101108
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Determination of the natural abundance delta15N of nortropane alkaloids by gas chromatography-isotope ratio mass spectrometry of their ethylcarbamate esters.
Analytical and bioanalytical chemistry 20100201
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Przeglad lekarski 20100101
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Determination of nitrogen-15 isotope fractionation in tropine: evaluation of extraction protocols for isotope ratio measurement by isotope ratio mass spectrometry.
Rapid communications in mass spectrometry : RCM 20091201
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Molecular cloning and characterization of two tropinone reductases in Anisodus acutangulus and enhancement of tropane alkaloid production in AaTRI-transformed hairy roots.
Biotechnology and applied biochemistry 20091023
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Synthesis of heteroaromatic tropeines and heterogeneous binding to glycine receptors.
Bioorganic & medicinal chemistry 20091001
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The development of ultrashort acting neuromuscular relaxant tropane derivatives.
Journal of critical care 20090301
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Potencies of cocaine methiodide on major cocaine targets in mice.
PloS one 20090101
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Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol.
Journal of medicinal chemistry 20081009
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The functional divergence of short-chain dehydrogenases involved in tropinone reduction.
The Plant journal : for cell and molecular biology 20080501
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Characterization of Atropa belladonna L. compounds by capillary electrophoresis-electrospray ionization-time of flight-mass spectrometry and capillary electrophoresis-electrospray ionization-ion trap-mass spectrometry.
Electrophoresis 20080501
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Synthesis of (nor)tropeine (di)esters and allosteric modulation of glycine receptor binding.
Bioorganic & medicinal chemistry 20080215
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Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs.
Pharmacological reports : PR 20080101
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Optimization of homonuclear 2D NMR for fast quantitative analysis: application to tropine-nortropine mixtures.
Journal of pharmaceutical and biomedical analysis 20070312
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Calystegines in potatoes with genetically engineered carbohydrate metabolism.
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Immunolocalisation of two tropinone reductases in potato (Solanum tuberosum L.) root, stolon, and tuber sprouts.
Planta 20061201
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Brassicaceae contain nortropane alkaloids.
Phytochemistry 20060901
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Quaternary derivatives of granatanol diesters: potent, ultrashort acting non-depolarizing neuromuscular relaxants.
Life sciences 20060704
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Tropinone reductases, enzymes at the branch point of tropane alkaloid metabolism.
Phytochemistry 20060201
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Sensitive and specific liquid chromatographic-tandem mass spectrometric assay for atropine and its eleven metabolites in rat urine.
Journal of pharmaceutical and biomedical analysis 20060123
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Spirit, mind and body in Chumash healing.
Evidence-based complementary and alternative medicine : eCAM 20051201
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Organotins disrupt the 11beta-hydroxysteroid dehydrogenase type 2-dependent local inactivation of glucocorticoids.
Environmental health perspectives 20051101
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Alkaloid content of the seeds from Erythroxylum Coca var. Coca.
Journal of forensic sciences 20051101
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Overexpression of tropinone reductases alters alkaloid composition in Atropa belladonna root cultures.
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Altered nitrogen metabolism associated with de-differentiated suspension cultures derived from root cultures of Datura stramonium studied by heteronuclear multiple bond coherence (HMBC) NMR spectroscopy.
Journal of experimental botany 20040501
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Preparing for chemical terrorism: stability of injectable atropine sulfate.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040401
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Induction of tropane alkaloid formation in transformed root cultures of Brugmansia suaveolens (Solanaceae).
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Alkaloids in plants and root cultures of Atropa belladonna overexpressing putrescine N-methyltransferase.
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Role of 5-HT3 receptors in the mechanisms of central pain syndrome.
Bulletin of experimental biology and medicine 20030601
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Biosynthesis of calystegines: 15N NMR and kinetics of formation in root cultures of Calystegia sepium.
Phytochemistry 20030201
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Structure-activity relationships among derivatives of dicarboxylic acid esters of tropine.
Pharmacology & therapeutics 20021001
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Molecular cloning, expression and characterization of tropinone reductase II, an enzyme of the SDR family in Solanum tuberosum (L.).
Plant molecular biology 20020201
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Receptor binding studies of soft anticholinergic agents.
AAPS pharmSci 20011201
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Calystegines in Calystegia sepium derive from the tropane alkaloid pathway.
Phytochemistry 20011101
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Photochemical N-demethylation of alkaloids.
Bioorganic & medicinal chemistry letters 20010226
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Atropine Metabolism by Pseudomonas sp. Strain AT3: Evidence for Nortropine as an Intermediate in Tropine Breakdown and Reactions Leading to Succinate.
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