136-47-0 | Tetracaine, HCl

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$14.00	$10.00
5g	98%	in stock	$36.00	$25.00
25g	98%	in stock	$96.00	$67.00
100g	98%	in stock	$293.00	$205.00

Description

• Catalog Number: AI32390
• Chemical Name: Tetracaine, HCl
• CAS Number: 136-47-0
• Molecular Formula: C15H25ClN2O2
• Molecular Weight: 300.8242
• MDL Number: MFCD00038912
• SMILES: CCCCNc1ccc(cc1)C(=O)OCCN(C)C.Cl
• NSC Number: 757337

Computed Properties

• Complexity: 249
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 9

Literature

• Relief of palatal injection pain by liposome-encapsulated 2% lignocaine prepared by ultrasonic dental scaler.

  The British journal of oral & maxillofacial surgery 20121201

• Interaction of local anesthetics with lipid bilayers investigated by ¹H MAS NMR spectroscopy.

  Biochimica et biophysica acta 20121201

• Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial access: a double-blind, randomized trial.

  British journal of anaesthesia 20121101

• Cross-over study of topical anaesthesia with tetracaine solution for transoral rigid laryngoscopy.

  The Journal of laryngology and otology 20121101

• Formation of drug/surfactant catanionic vesicles and their application in sustained drug release.

  International journal of pharmaceutics 20121015

• Effects of application durations and heat on the pharmacokinetic properties of drug delivered by a lidocaine/tetracaine patch: a randomized, open-label, controlled study in healthy volunteers.

  Clinical therapeutics 20121001

• Prospective, double-masked, randomized trial comparing lidocaine gel to tetracaine drops in femtosecond laser-assisted LASIK.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20121001

• Hemodynamic changes during spinal anesthesia in premature infants with congenital heart disease undergoing inguinal hernia correction.

  Paediatric anaesthesia 20120901

• The cardiovascular effects and pharmacokinetics of intranasal tetracaine plus oxymetazoline: preliminary findings.

  Journal of the American Dental Association (1939) 20120801

• Distribution of embutramide and mebezonium iodide in a suicide after tanax injection.

  Journal of analytical toxicology 20120601

• [Effect of adding phenylephrine on spinal anesthesia with tetracaine in elderly patients].

  Masui. The Japanese journal of anesthesiology 20120601

• Secondary tracheoesophageal puncture and myotomy--A novel outpatient technique.

  Head & neck 20120501

• Function and expression of ryanodine receptors and inositol 1,4,5-trisphosphate receptors in smooth muscle cells of murine feed arteries and arterioles.

  The Journal of physiology 20120415

• Nasal tetracaine spray-induced methemoglobinemia.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20120401

• Factors affecting patients' pain intensity during in office intravitreal injection procedure.

  Retina (Philadelphia, Pa.) 20120401

• A comparison of Rapydan® patch and Ametop® gel for venous cannulation.

  Anaesthesia 20120401

• Anaesthetic plus dilating gel improves pupil dilation for cataract surgery.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20120401

• The safety of flexible fibre-optic bronchoscopy and proceduralist-administered sedation: a tertiary referral centre experience.

  Internal medicine journal 20120301

• Effect of topical anesthetic agents and ethanol on corneoepithelial wound healing in an ex vivo whole-globe porcine model.

  Journal of cataract and refractive surgery 20120301

• Eyelid anaesthesia using tetracaine gel in the treatment of paediatric superglue tarsorrhaphy.

  Eye (London, England) 20120201

• A comparison of amethocaine and liposomal lidocaine cream as a pain reliever before venipuncture in children: a randomized control trial.

  Pediatric emergency care 20120201

• Determination of tetracaine hydrochloride by fluorescence quenching method with some aromatic amino acids as probes.

  Journal of fluorescence 20120101

• Improvement of tetracaine antinociceptive effect by inclusion in cyclodextrins.

  Journal of drug targeting 20120101

• [Morphological studies in different avian species on artefacts induced by euthanasia with T 61 ' or Pentobarbital (Narcoren)].

  Berliner und Munchener tierarztliche Wochenschrift 20120101

• Clinical efficacy of tetracaine anesthetic paste.

  General dentistry 20120101

• Assessment of the efficacy of topical anesthetics using the tactile spatial resolution method.

  Acta dermatovenerologica Croatica : ADC 20120101

• Subconjunctival bevacizumab for corneal neovascularization secondary to topical anesthetic abuse.

  Cutaneous and ocular toxicology 20111201

• Immediate vesicular eruption caused by topical 23% lidocaine 7% tetracaine ointment in a patient scheduled for laser therapy: a new adverse drug reaction.

  Journal of cosmetic dermatology 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Halogen substituents on the aromatic moiety of the tetracaine scaffold improve potency of cyclic nucleotide-gated channel block.

  Bioorganic & medicinal chemistry letters 20111101

• [Coffee ir T-61?].

  Tijdschrift voor diergeneeskunde 20111101

• Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells.

  Breast cancer research and treatment 20111001

• Myringotomy and ventilation tube insertion with minims tetracaine drops.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20111001

• Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+ content in rat ventricular myocytes.

  The Journal of physiology 20111001

• Novel gel formulations with catanionic aggregates enable prolonged drug release and reduced skin permeation.

  The Journal of pharmacy and pharmacology 20111001

• An impedance QCM study on the partitioning of bioactive compounds in supported phospholipid bilayers.

  Colloids and surfaces. B, Biointerfaces 20110901

• The effectiveness of Oraqix versus TAC(a) for placement of orthodontic temporary anchorage devices.

  The Angle orthodontist 20110901

• Three independent mechanisms contribute to tetracaine inhibition of cardiac calcium release channels.

  Journal of molecular and cellular cardiology 20110901

• Allergic contact dermatitis caused by tetracaine contained in otic drops.

  Contact dermatitis 20110901

• Effect of reversible inactivation of reuniens nucleus on memory processing in passive avoidance task.

  Behavioural brain research 20110801

• High-throughput screening of drug-lipid membrane interactions via counter-propagating second harmonic generation imaging.

  Analytical chemistry 20110801

• [Comparison of intrathecal morphine and buprenorphine for postoperative analgesia in cesarean delivery].

  Masui. The Japanese journal of anesthesiology 20110801

• Cyclic nucleotide-gated channel block by hydrolysis-resistant tetracaine derivatives.

  Journal of medicinal chemistry 20110714

• In situ calibration of nucleoplasmic versus cytoplasmic Ca²+ concentration in adult cardiomyocytes.

  Biophysical journal 20110518

• Heterogeneous function of ryanodine receptors, but not IP3 receptors, in hamster cremaster muscle feed arteries and arterioles.

  American journal of physiology. Heart and circulatory physiology 20110501

• A comparison of the effects of preanesthetic administration of crystalloid versus colloid on intrathecal spread of isobaric spinal anesthetics and cerebrospinal fluid movement.

  Anesthesia and analgesia 20110401

• Randomized trial of anesthetic methods for intravitreal injections.

  Retina (Philadelphia, Pa.) 20110301

• Liquid chromatography-tandem mass spectrometry detection of the quaternary ammonium compound mebezonium as an active ingredient in t61.

  Journal of analytical toxicology 20110301

• Intravitreal injection anesthesia--comparison of different topical agents: a prospective randomized controlled trial.

  American journal of ophthalmology 20110201

• Determination of stimulants and narcotics as well as their in vitro metabolites by online CE-ESI-MS.

  Electrophoresis 20110201

• Duration of corneal anaesthesia following multiple doses and two concentrations of tetracaine hydrochloride eyedrops on the normal equine cornea.

  Equine veterinary journal 20110101

• Determination of tear break-up time reference values and ocular tolerance of tetracaine hydrochloride eyedops in healthy horses.

  Equine veterinary journal 20110101

• Ab externo trabeculectomy performed under topical anesthesia supplemented by conscious sedation.

  Cirugia y cirujanos 20110101

• Ca2+ paradox injury mediated through TRPC channels in mouse ventricular myocytes.

  British journal of pharmacology 20101201

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Spontaneous Ca2+ sparks and Ca2+ homeostasis in a minimal model of permeabilized ventricular myocytes.

  American journal of physiology. Heart and circulatory physiology 20101201

• Lidocaine/tetracaine medicated plaster: in minor dermatological and needle puncture procedures.

  Drugs 20101112

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Surgery for esotropia under topical anesthesia.

  Ophthalmology 20101001

• Cetacaine-induced complication during transesophageal echocardiography placement.

  Journal of cardiothoracic and vascular anesthesia 20100801

• Dimethylformamide metabolism following self-harm using a veterinary euthanasia product.

  Clinical toxicology (Philadelphia, Pa.) 20100801

• Microcalorimetric and zeta potential study on binding of drugs on liposomes.

  Colloids and surfaces. B, Biointerfaces 20100701

• [Topical anesthesia before vascular access in children. Comparison of a warmth-producing lidocaine-tetracaine patch with a lidocaine-prilocaine patch].

  Der Anaesthesist 20100601

• Cost benefit analysis of amethocaine (Ametop) compared with EMLA for intravenous cannulation in a children's emergency department.

  Emergency medicine journal : EMJ 20100601

• Simultaneous determination of procaine, lidocaine, ropivacaine, tetracaine and bupivacaine in human plasma by high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100501

• Fibroblast growth factor and insulin-like growth factor rescue growth cones of sensory neurites from collapse after tetracaine-induced injury.

  Anesthesia and analgesia 20100501

• CaMKII-dependent diastolic SR Ca2+ leak and elevated diastolic Ca2+ levels in right atrial myocardium of patients with atrial fibrillation.

  Circulation research 20100402

• A comparison of topical application of 1% tetracaine gel before and after the procedure in removal of cutaneous pigmentation with Q-switched neodymium-doped yttrium aluminium garnet laser (1064/532 nm).

  Photomedicine and laser surgery 20100401

• A rapid methodology for the characterization of dialkyl tertiary amine-N-oxide metabolites using structurally dependent dissociation pathways and reconstructed ion current chromatograms.

  Analytical chemistry 20100315

• Oral acetaminophen (paracetamol) for additional analgesia in phacoemulsification cataract surgery performed using topical anesthesia Randomized double-masked placebo-controlled trial.

  Journal of cataract and refractive surgery 20100301

• Efficacy of topical anesthesia for foldable phakic intraocular lens implantation for the correction of myopia.

  Journal of cataract and refractive surgery 20100301

• Brain penetration of local anaesthetics in the rat: Implications for experimental neuroscience.

  Journal of neuroscience methods 20100215

• Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

  Journal of molecular and cellular cardiology 20100201

• The effect of combined topical-intracameral anaesthesia on neuroleptic requirements during cataract surgery.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20100201

• The effect of a new topical local anaesthetic delivery system on forearm skin blood flow reactivity.

  Anaesthesia 20100201

• Lidocaine spray vs tetracaine solution for transnasal fiber-optic laryngoscopy.

  American journal of otolaryngology 20100101

• Formulation, characterization and testing of tetracaine hydrochloride-loaded albumin-chitosan microparticles for ocular drug delivery.

  Journal of microencapsulation 20100101

• Simultaneous determination of tetracaine, proline, and enoxacin in human urine by CE with ECL detection.

  Journal of chromatographic science 20100101

• Functional deficits after intraneural injection during interscalene block.

  Regional anesthesia and pain medicine 20100101

• Evaluation of the depth and duration of anesthesia from heated lidocaine/tetracaine (Synera) patches compared with placebo patches applied to healthy adult volunteers.

  Regional anesthesia and pain medicine 20100101

• Lidocaine spray versus tetracaine solution for monopolar submucosal diathermy for inferior turbinate hypertrophy.

  B-ENT 20100101

• Reliability and validity of observer ratings of pain using the visual analog scale (VAS) in infants undergoing immunization injections.

  Pain 20091215

• Combined deep topical and superior subconjunctival anesthesia for extracapsular cataract extraction in a rural eye camp.

  Anesthesia and analgesia 20091201

• Tetracaine (ametop) compared to placebo for reducing pain associated with intramuscular injection of palivizumab (synagis).

  Journal of pediatric nursing 20091201

• Local-anaesthetic day-case treatment of Stelling type 1 ulnar duplication in babies up to 4 months of age.

  The Journal of hand surgery, European volume 20091201

• Only tetracaine and not other local anaesthetics induce apoptosis in rat cortical astrocytes.

  British journal of anaesthesia 20091101

• Interdigitation and vesicle-to-micelle transformation induced by a local anesthetic tetracaine in phospholipids bilayers.

  Colloids and surfaces. B, Biointerfaces 20090801

• The contribution of inositol 1,4,5-trisphosphate and ryanodine receptors to agonist-induced Ca(2+) signaling of airway smooth muscle cells.

  American journal of physiology. Lung cellular and molecular physiology 20090801

• [Clinical observation on effect of auricular point injection combined with superficial anesthesia for nasal endoscopy surgery].

  Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20090801

• Randomised controlled trial on the effectiveness of lidocaine gel vs tetracaine drops as the sole topical anaesthetic agent for primary pterygium surgery.

  Eye (London, England) 20090701

• Implications of regular solution theory on the release mechanism of catanionic mixtures from gels.

  Colloids and surfaces. B, Biointerfaces 20090701

• Energetic state is a strong regulator of sarcoplasmic reticulum Ca2+ loss in cardiac muscle: different efficiencies of different energy sources.

  Cardiovascular research 20090701

• Does topical application of adrenaline on nasal mucosa induce significant haemodynamic changes under general anaesthesia?

  European journal of anaesthesiology 20090701

• Effect of tetracaine-induced spinal anesthesia on pial microcirculation in pentobarbital anesthetized rats.

  Journal of neurosurgical anesthesiology 20090701

• Amethocaine versus EMLA for successful intravenous cannulation in a children's emergency department: a randomised controlled study.

  Emergency medicine journal : EMJ 20090701

• Mitochondrial free calcium regulation during sarcoplasmic reticulum calcium release in rat cardiac myocytes.

  Journal of molecular and cellular cardiology 20090601

• Cooling tetracaine to reduce pain of instillation before surgery.

  Eye (London, England) 20090601

• Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis.

  Biomedical chromatography : BMC 20090501

• Gel formation in systems composed of drug containing catanionic vesicles and oppositely charged hydrophobically modified polymer.

  Colloids and surfaces. B, Biointerfaces 20090501

• Spinal anesthesia with isobaric tetracaine in patients with previous lumbar spinal surgery.

  Yonsei medical journal 20090430

• Structural determinants of drugs acting on the Nav1.8 channel.

  The Journal of biological chemistry 20090417

• Calcium store-mediated signaling in sustentacular cells of the mouse olfactory epithelium.

  Glia 20090415

• Assessment of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular cardiomyocytes.

  Biophysical journal 20090408

• Long-lasting allergic contact blepharoconjunctivitis to phenylephrine eyedrops.

  Allergy 20090401

• The use of topical anaesthesia during repair of minor lacerations in Departments of Emergency Medicine: a literature review.

  International emergency nursing 20090401

• Localized contact urticaria caused by lidocaine/tetracaine peel.

  Archives of dermatology 20090401

• Effect of reversible inactivation of the reuniens nucleus on spatial learning and memory in rats using Morris water maze task.

  Behavioural brain research 20090302

• Corneal transplant with topical tetracaine 1% as the sole anaesthetic agent.

  Acta ophthalmologica 20090301

• Methemoglobinemia related to local anesthetics: a summary of 242 episodes.

  Anesthesia and analgesia 20090301

• A national survey of the anesthetic management of tonsillectomy surgery in children.

  Paediatric anaesthesia 20090201

• Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access.

  British journal of anaesthesia 20090201

• [Peritopic anesthesia in cataract surgery].

  Archivos de la Sociedad Espanola de Oftalmologia 20090201

• Rapid activation of plasticity-associated gene transcription in hippocampal neurons provides a mechanism for encoding of one-trial experience.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128

• Resonance Rayleigh scattering spectra, non-linear scattering spectra of tetracaine hydrochloride-erythrosin system and its analytical application.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090101

• Antibacterial activity of preservative-free topical anesthetic drops in current use in ophthalmology departments.

  Cornea 20090101

• [Effect of double anaesthetic Colicursi (tetracaine 0.1% and oxybuprocaine 0.4%) on central and paracentral corneal thickness].

  Archivos de la Sociedad Espanola de Oftalmologia 20090101

• Topical anesthesia in strabismus surgery: a review of 101 cases.

  Journal of pediatric ophthalmology and strabismus 20090101

• Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery.

  BMC ophthalmology 20090101

• Comparative efficacy of 2 topical anesthetics for the placement of orthodontic temporary anchorage devices.

  Anesthesia progress 20090101

• Development of a liquid chromatography-tandem mass spectrometry method for an euthanasic veterinarian drug: Tanax.

  Journal of pharmaceutical and biomedical analysis 20081104

• Access and binding of local anesthetics in the closed sodium channel.

  Molecular pharmacology 20081001

• Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics.

  Journal of cardiovascular pharmacology 20081001

• Anesthetic keratopathy after photorefractive keratectomy.

  Journal of cataract and refractive surgery 20081001

• Retrobulbar versus topical anesthesia for phacoemulsification.

  Pakistan journal of biological sciences : PJBS 20081001

• Function of Ca(2+) release channels in Purkinje cells that survive in the infarcted canine heart: a mechanism for triggered Purkinje ectopy.

  Circulation. Arrhythmia and electrophysiology 20080913

• Peripheral refraction in normal infant rhesus monkeys.

  Investigative ophthalmology & visual science 20080901

• Transient hyperaemic response to assess vascular reactivity of skin: effect of topical anaesthesia.

  British journal of anaesthesia 20080901

• Temperature-sensitive TREK currents contribute to setting the resting membrane potential in embryonic atrial myocytes.

  The Journal of physiology 20080801

• Optimizing local anesthesia for grommet insertion: eutectic mixture of local anaesthetics versus Ametop: a randomized clinical trial.

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20080801

• Cataract surgery complication rates.

  Ophthalmology 20080801

• Catanionic aggregates formed from drugs and lauric or capric acids enable prolonged release from gels.

  Journal of colloid and interface science 20080715

• Warm lidocaine/tetracaine patch versus placebo before pediatric intravenous cannulation: a randomized controlled trial.

  Annals of emergency medicine 20080701

• Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation.

  Heart rhythm 20080701

• Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anesthetics.

  Drug delivery 20080601

• Comparison of two column characterisation systems based on pharmaceutical applications.

  Journal of chromatography. A 20080502

• Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production.

  Nature 20080424

• Topical anaesthesia and intravenous cannulation success in paediatric patients: a randomized double-blind trial.

  British journal of anaesthesia 20080401

• Therapeutic experience from 1428 patients with pediatric tracheobronchial foreign body.

  Journal of pediatric surgery 20080401

• Synergistically enhanced transdermal permeation and topical analgesia of tetracaine gel containing menthol and ethanol in experimental and clinical studies.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080301

• Partial inhibition of sarcoplasmic reticulum ca release evokes long-lasting ca release events in ventricular myocytes: role of luminal ca in termination of ca release.

  Biophysical journal 20080301

• Lipid composition alters drug action at the nicotinic acetylcholine receptor.

  Molecular pharmacology 20080301

• The effects of prehydration on the properties of cerebrospinal fluid and the spread of isobaric spinal anesthetic drug.

  Anesthesia and analgesia 20080301

• Brief report: a randomized controlled trial of Synera versus lidocaine for epidural needle insertion in labouring parturients.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20080301

• Sub-plasmalemmal [Ca2+]i upstroke in myocytes of the guinea-pig small intestine evoked by muscarinic stimulation: IP3R-mediated Ca2+ release induced by voltage-gated Ca2+ entry.

  Cell calcium 20080201

• Modification of smooth muscle Ca2+-sparks by tetracaine: evidence for sequential RyR activation.

  Cell calcium 20080201

• [Fluorescence quenching reaction of tetracaine hydrochloride with erythrosine and their analytical applications].

  Guang pu xue yu guang pu fen xi = Guang pu 20080201

• Block of cyclic nucleotide-gated channels by tetracaine derivatives: role of apolar interactions at two distinct locations.

  Bioorganic & medicinal chemistry letters 20080115

• Systemic exposure to lidocaine and tetracaine is low after an application of a lidocaine 7%-tetracaine 7% peel in adults.

  International journal of dermatology 20080101

• Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials.

  Regional anesthesia and pain medicine 20080101

• Topical amethocaine gel 4% for intramuscular injection in term neonates: a double-blind, placebo-controlled, randomized trial.

  Clinical therapeutics 20080101

• Patch-test reactions to topical anesthetics: retrospective analysis of cross-sectional data, 2001 to 2004.

  Dermatitis : contact, atopic, occupational, drug 20080101

• Effect of topical anesthetics on intraocular pressure and pachymetry.

  European journal of ophthalmology 20080101

• Effects on pupil size and accommodation from topical lidocaine hydrochloride and tetracaine hydrochloride.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071201

• Toxicities of topical ophthalmic anesthetics.

  Expert opinion on drug safety 20071101

• Phacoemulsification complication rates.

  Ophthalmology 20071101

• IP3-dependent nuclear Ca2+ signalling in the mammalian heart.

  The Journal of physiology 20071015

• Caffeine-activated large-conductance plasma membrane cation channels in cardiac myocytes: characteristics and significance.

  American journal of physiology. Heart and circulatory physiology 20071001

• Diplopia after topical pharyngeal anesthesia for transesophageal echocardiography.

  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20071001

• Use of the Synera patch for local anesthesia before vascular access procedures: a randomized, double-blind, placebo-controlled study.

  Pain medicine (Malden, Mass.) 20070901

• The lidocaine/tetracaine peel: a novel topical anesthetic for dermatologic procedures in adult patients.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20070901

• Routine immunization practices: use of topical anesthetics and oral analgesics.

  Pediatrics 20070901

• Drug interaction or drug overdose? Supercaine revisited.

  Anesthesia and analgesia 20070801

• Topical anaesthesia alone versus topical anaesthesia with intracameral lidocaine for phacoemulsification.

  The Cochrane database of systematic reviews 20070718

• Role of cADPR in sodium nitroprusside-induced opossum esophageal longitudinal smooth muscle contraction.

  American journal of physiology. Gastrointestinal and liver physiology 20070601

• Tetracaine-membrane interactions: effects of lipid composition and phase on drug partitioning, location, and ionization.

  Biophysical journal 20070601

• The effect of topical tetracaine eye drops on emergence behavior and pain relief after strabismus surgery.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20070601

• Effects of local anesthetics on opioid inhibition of calcium current in rat dorsal root ganglion neurons.

  Neuroscience letters 20070518

• Ca2+-sparks constitute elementary building blocks for global Ca2+-signals in myocytes of retinal arterioles.

  Cell calcium 20070501

• Acetylcholine-induced asynchronous calcium waves in intact human bronchial muscle bundle.

  American journal of respiratory cell and molecular biology 20070501

• Non-thiol reagents regulate ryanodine receptor function by redox interactions that modify reactive thiols.

  Antioxidants & redox signaling 20070501

• Influence of the baricity of a local anaesthetic agent on sedation with propofol during spinal anaesthesia.

  British journal of anaesthesia 20070401

• Safety of cataract surgery under topical anesthesia with oral sedation without anesthetic monitoring.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20070401

• The safety and efficacy of spinal anesthesia for surgery in infants.

  Anesthesia and analgesia 20070301

• Dilation efficacy: is 1% cyclopentolate enough?

  Optometry (St. Louis, Mo.) 20070301

• Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.

  Circulation research 20070216

• CaM or cAMP: linking beta-adrenergic stimulation to 'leaky' RyRs.

  Circulation research 20070216

• Possible malignant hyperthermia during spinal anaesthesia with tetracaine.

  Anaesthesia 20070201

• Cocaine versus tetracaine in septoplasty: a prospective, randomized, controlled trial.

  The Journal of laryngology and otology 20070201

• Tetracaine hydrochloride 0.5% versus lidocaine 2% jelly as a topical anesthetic agent in cataract surgery: comparative clinical trial.

  Journal of cataract and refractive surgery 20070101

• [7-year survey of anesthesia for cesarean section--comparison of tetracaine and bupivacaine as intrathecal anesthetic agents].

  Masui. The Japanese journal of anesthesiology 20070101

• How effective is tetracaine 4% gel, before a venipuncture, in reducing procedural pain in infants: a randomized double-blind placebo controlled trial.

  BMC pediatrics 20070101

• Safety and efficacy of two ocular anesthetic methods for phacoemulsification: topical anesthesia and viscoanesthesia (VisThesia).

  European journal of ophthalmology 20070101

• Warnings for makers of compounded pain products.

  FDA consumer 20070101

• Surface anesthesia for office-based retinal procedures.

  Retina (Philadelphia, Pa.) 20070101

• A study on the influence of emulsion droplet size on the skin penetration of tetracaine.

  Skin pharmacology and physiology 20070101

• Changes in percutaneous oxygen tension induced by spinal anesthesia.

  Journal of anesthesia 20070101

• KNO3/benzocaine/tetracaine gel use for maintenance visit pain control.

  General dentistry 20070101

• Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101

• A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part 1.

  Arzneimittel-Forschung 20070101

• Urinary catheterization may not be necessary in minor surgery under spinal anesthesia with long-acting local anesthetics.

  Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20061201

• Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding.

  Journal of molecular modeling 20060901

• Tetracaine at a small concentration delayed nerve growth without destroying neurites and growth cones.

  Anesthesia and analgesia 20060901

• Topical reaction.

  Paediatric nursing 20060901

• Solid-state characterization of non-stoichiometric hydrates of ester-type local anaesthetics. Part XI. Crystal polymorphism of local anaesthetic drugs.

  International journal of pharmaceutics 20060831

• Population patch clamp improves data consistency and success rates in the measurement of ionic currents.

  Journal of biomolecular screening 20060801

• EMLA and amethocaine for reduction of children's pain associated with needle insertion.

  The Cochrane database of systematic reviews 20060719

• Efficacy of intraoral topical anesthetics in children.

  Journal of dentistry 20060701

• Cellular mechanism for spontaneous calcium oscillations in astrocytes.

  Acta pharmacologica Sinica 20060701

• [The short-term ventilation tube].

  Laryngo- rhino- otologie 20060701

• Does amethocaine gel influence blood results obtained from capillary sampling?

  Paediatric nursing 20060701

• Double-blind study on the effects of topical anesthesia on laryngeal secretions.

  Journal of voice : official journal of the Voice Foundation 20060601

• Topical local anaesthetic (tetracaine) reduces pain from botulinum toxin injections for axillary hyperhidrosis.

  The British journal of surgery 20060601

• Effect of the composition of lecithin/n-propanol/isopropyl myristate/water microemulsions on barrier properties of mice skin for transdermal permeation of tetracaine hydrochloride: in vitro.

  Colloids and surfaces. B, Biointerfaces 20060601

• Methemoglobinemia after fiberoptic intubation in a patient with an unstable cervical fracture: a case report.

  Journal of spinal disorders & techniques 20060601

• Contact dermatitis and bradycardia in a preterm infant given tetracaine 4% gel.

  Therapeutic drug monitoring 20060601

• Site-specific skin reactions to amethocaine.

  Paediatric nursing 20060601

• Comparison of two approaches to brachial plexus anesthesia for proximal upper extremity surgery: interscalene and intersternocleidomastoid.

  AANA journal 20060601

• Reducing ryanodine receptor open probability as a means to abolish spontaneous Ca2+ release and increase Ca2+ transient amplitude in adult ventricular myocytes.

  Circulation research 20060526

• Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymers.

  Journal of controlled release : official journal of the Controlled Release Society 20060501

• Polymorphism and pseudopolymorphism of salicaine and salicaine hydrochloride crystal polymorphism of local anaesthetic drugs, part V.

  Journal of pharmaceutical sciences 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Comparison of ethyl chloride spray with topical anaesthetic in children experiencing venepuncture.

  Paediatric nursing 20060401

• The effects of an AMPA receptor antagonist on the neurotoxicity of tetracaine intrathecally administered in rabbits.

  Anesthesia and analgesia 20060301

• Transdermal permeation of tetracaine hydrochloride by lecithin microemulsion: in vivo.

  Colloids and surfaces. B, Biointerfaces 20060301

• Methemoglobinemia and acute hemolysis after tetracaine lozenge use.

  Journal of critical care 20060301

• Molecular mechanisms and binding site location for the noncompetitive antagonist crystal violet on nicotinic acetylcholine receptors.

  Biochemistry 20060221

• Intravenous morphine and topical tetracaine for treatment of pain in [corrected] neonates undergoing central line placement.

  JAMA 20060215

• Tetracaine oral gel in patients treated with radiotherapy for head-and-neck cancer: final results of a phase II study.

  International journal of radiation oncology, biology, physics 20060201

• Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease.

  Neurobiology of aging 20060201

• Efficient characterization of use-dependent ion channel blockers by real-time monitoring of channel state.

  Assay and drug development technologies 20060201

• Mechanical characterization and drug permeation properties of tetracaine-loaded bioadhesive films for percutaneous local anesthesia.

  Drug development and industrial pharmacy 20060201

• Liquid-phase microextraction combined with high-performance liquid chromatography for the determination of local anaesthetics in human urine.

  Journal of pharmaceutical and biomedical analysis 20060123

• The safety and efficacy of spinal anesthesia for surgery in infants: the Vermont Infant Spinal Registry.

  Anesthesia and analgesia 20060101

• Discomfort and tetracaine.

  Ophthalmology 20060101

• Interaction of botulinum toxin type A with local anesthetic agents: an experimental study with rabbits.

  Aesthetic plastic surgery 20060101

• In vitro interactions with the Cytochrome P450 system, toxicity, and local anaesthetic effects of Fomocaine Alkylmorpholine derivatives in rats.

  Arzneimittel-Forschung 20060101

• Pain induced by phacoemulsification without sedation using topical or peribulbar anesthesia.

  Journal of cataract and refractive surgery 20060101

• Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors.

  The international journal of biochemistry & cell biology 20060101

• How effective is tetracaine 4% gel, before a peripherally inserted central catheter, in reducing procedural pain in infants: a randomized double-blind placebo controlled trial [ISRCTN75884221].

  BMC medicine 20060101

• Differential sensitivity to perchlorate and caffeine of tetracaine-resistant Ca2+ release in frog skeletal muscle.

  Journal of muscle research and cell motility 20060101

• Pharmacological and toxicological testing of the enantiomers of two chiral fomocaine alkylmorpholine derivatives in comparison to their in vitro interactions on drug metabolism in rats.

  Arzneimittel-Forschung 20060101

• Re: 'the tetracaine provocation test (TPT) for inducing early involutional entropion'.

  Ophthalmic plastic and reconstructive surgery 20060101

• The use of tetracaine 0.25% solution in nasal packing removal.

  American journal of rhinology 20060101

• Restoring theta-like rhythmicity in rats restores initial learning in the Morris water maze.

  Hippocampus 20060101

• Photo-induced covalent attachment of agonists as a tool to study allosteric mechanisms of nicotinic acetylcholine receptors.

  Journal of molecular neuroscience : MN 20060101

• IP3-mediated Ca2+ increases do not involve the ryanodine receptor, but ryanodine receptor antagonists reduce IP3-mediated Ca2+ increases in guinea-pig colonic smooth muscle cells.

  The Journal of physiology 20051201

• The use of peripheral nerve blocks at the elbow for carpal tunnel release.

  Journal of clinical anesthesia 20051201

• Menthol facilitates the skin analgesic effect of tetracaine gel.

  International journal of pharmaceutics 20051123

• A comparison of two double-injection techniques for peribulbar block analgesia: infero-temporal plus supero-medial vs. infero-temporal plus medial-percaruncular.

  Acta anaesthesiologica Scandinavica 20051101

• Hypobaric spinal anesthesia with 0.2% tetracaine for total joint hip arthroplasy.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20051101

• Topical anesthetics for dermal instrumentation: a systematic review of randomized, controlled trials.

  Annals of emergency medicine 20051001

• Topical anesthetic sprays directly associated with a serious, sometimes fatal adverse drug reaction: methemoglobinemia.

  Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20051001

• LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast.

  Genes & genetic systems 20051001

• Modifications to the tetracaine scaffold produce cyclic nucleotide-gated channel blockers with widely varying efficacies.

  Journal of medicinal chemistry 20050908

• Allergic contact dermatitis to a urologic lubricant.

  Dermatitis : contact, atopic, occupational, drug 20050901

• Kinetics of interaction of local anesthetics with human serum albumin.

  Bulletin of experimental biology and medicine 20050901

• Minimal sodium channel pore consisting of S5-P-S6 segments preserves intracellular pharmacology.

  Biochemical and biophysical research communications 20050819

• Hazard of compounded anesthetic gel.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050715

• The nerve root entry zone is highly vulnerable to intrathecal tetracaine in rabbits.

  Anesthesia and analgesia 20050701

• Calcium oscillations in interstitial cells of the rabbit urethra.

  The Journal of physiology 20050601

• Local anesthetics facilitate ion transport across lipid planar bilayer membranes under an electric field: dependence on type of lipid bilayer.

  Colloids and surfaces. B, Biointerfaces 20050525

• Differential effects of bupivacaine and tetracaine on capsaicin-induced currents in dorsal root ganglion neurons.

  Neuroscience letters 20050520

• Postoperative analgesia after spinal blockade in infants and children undergoing cardiac surgery.

  Anesthesia and analgesia 20050501

• Randomised controlled trial of sub-Tenon's block versus topical anaesthesia for cataract surgery: a comparison of patient satisfaction.

  The British journal of ophthalmology 20050301

• Comparative efficacy and costs of various topical anesthetics for repair of dermal lacerations: a systematic review of randomized, controlled trials.

  Journal of clinical anesthesia 20050301

• Evaluation of the S-Caine Peel for induction of local anesthesia for laser-assisted tattoo removal: randomized, double-blind, placebo-controlled, multicenter study.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20050301

• Randomized, double-blind, placebo-controlled study evaluating the lidocaine/tetracaine patch for induction of local anesthesia prior to minor dermatologic procedures in geriatric patients.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20050301

• Intravenous ketamine sedation for painful oncology procedures.

  Paediatric anaesthesia 20050201

• A randomized controlled trial to evaluate S-Caine patch for reducing pain associated with vascular access in children.

  Anesthesiology 20050201

• Self-warming lidocaine/tetracaine patch effectively and safely induces local anesthesia during minor dermatologic procedures.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20050201

• [Topical anesthesia as routine procedure in cataract surgery -- evaluation of pain and complications in 1010 cases].

  Klinische Monatsblatter fur Augenheilkunde 20050101

• Effects of local anesthetics on human bladder contractility.

  Neurourology and urodynamics 20050101

• A critical review of the topical local anesthetic amethocaine (Ametop) for pediatric pain.

  Paediatric drugs 20050101

• [Tetracaine-induced systemic contact-type dermatitis].

  Allergologia et immunopathologia 20050101

• [Comparison between the pain induced by phacoemulsification with topical anesthesia and by peribulbar anesthesia without sedation].

  Arquivos brasileiros de oftalmologia 20050101

• Rapid human skin permeation and topical anaesthetic activity of a new amethocaine microemulsion.

  Skin pharmacology and physiology 20050101

• Analysis of possible cross-contamination with the Venturi system atomizer.

  American journal of rhinology 20050101

• The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations.

  Pediatric emergency care 20041201

• Topical 4% amethocaine gel reduces the pain of subcutaneous measles-mumps-rubella vaccination.

  Pediatrics 20041201

• Effects of a corneal anesthetic on extinction of the classically conditioned nictitating membrane response in the rabbit (Oryctolagus cuniculus).

  Behavioral neuroscience 20041201

• Cocaine flakes versus tetracaine/adrenaline solution for local anaesthesia in septoplasty.

  Rhinology 20041201

• Minimal dosage of tetracaine supplemented with epinephrine for spinal anesthesia in anorectal surgery.

  Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20041201

• Relief of pain and anxiety in pediatric patients in emergency medical systems.

  Pediatrics 20041101

• X-ray scattering study of pike olfactory nerve: elastic, thermodynamic and physiological properties of the axonal membrane.

  Journal of molecular biology 20041008

• Anesthetic implications of Leigh's syndrome.

  Paediatric anaesthesia 20040901

• [Glucose attenuating local anesthetic-induced hemolysis].

  Masui. The Japanese journal of anesthesiology 20040901

• Methemoglobinemia: sudden dyspnea and oxyhemoglobin desaturation after esophagoduodenoscopy.

  Respiratory care 20040801

• Muscle surgery in patients with Graves' disease using topical anesthesia.

  Ophthalmology 20040801

• Allergic contact dermatitis from tetracaine in the beauty industry.

  Contact dermatitis 20040801

• Local anaesthetics--Nupercaine and Amethcaine.

  Anaesthesia and intensive care 20040801

• A Raman spectroscopic investigation of bioadhesive tetracaine local anaesthetic formulations.

  International journal of pharmaceutics 20040726

• Phase separation of cholesterol from phosphatidylserine-cholesterol mixtures in the presence of the local anesthetic tetracaine.

  Chemistry and physics of lipids 20040701

• Anesthesia affects olfaction and chemosensory event-related potentials.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20040601

• Requirement of ryanodine receptors for pacemaker Ca2+ activity in ICC and HEK293 cells.

  Journal of cell science 20040601

• Interaction of serotonin1A receptors from bovine hippocampus with tertiary amine local anesthetics.

  Cellular and molecular neurobiology 20040601

• Combined topical and intracameral anesthesia in penetrating keratoplasty.

  Cornea 20040501

• Rapid skin anesthesia using a new topical amethocaine formulation: a preclinical study.

  Anesthesia and analgesia 20040501

• Tetracycline compound placement to prevent dry socket: a postoperative study of 200 impacted mandibular third molars.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20040501

• Tongue entrapment in an aluminum juice can.

  Pediatric emergency care 20040401

• Pupil dilatation with intracameral 1% lidocaine during glaucoma filtering surgery.

  American journal of ophthalmology 20040401

• Intracellular calcium increases in growth cones exposed to tetracaine.

  Anesthesia and analgesia 20040301

• Inclusion of epinephrine to hyperbaric tetracaine and the supine position enhance the cephalad spread of spinal anaesthesia compared with hyperbaric teracaine alone in the lithotomy position.

  Acta anaesthesiologica Scandinavica 20040301

• Enhanced production and action of cyclic ADP-ribose during oxidative stress in small bovine coronary arterial smooth muscle.

  Microvascular research 20040301

• A rapid and sensitive high-performance liquid chromatography method for determination of embutramide (a Tanax or T61 component) in human blood with photodiode-array UV detection.

  Journal of analytical toxicology 20040301

• The need for caution with topical anesthesia during endoscopic procedures, as liberal use may result in methemoglobinemia.

  Journal of clinical gastroenterology 20040301

• Arachidonic acid regulates two Ca2+ entry pathways via nitric oxide.

  Cellular signalling 20040201

• The use of EMLA cream to decrease venipuncture pain in children.

  Journal of pediatric nursing 20040201

• A randomized, double-blind, placebo-controlled study of the efficacy of tetracaine gel (Ametop) for pain relief during topical photodynamic therapy.

  The British journal of dermatology 20040201

• Effect of receptor solution specific conductivity on iontophoresis of tetracaine hydrochloride.

  Yao xue xue bao = Acta pharmaceutica Sinica 20040201

• Effects of alpha-scorpion toxin, tityustoxin on the release of [3H] dopamine of rat brain prefrontal cortical slices.

  Neurochemistry international 20040101

• Local anesthetics worsen renal function after ischemia-reperfusion injury in rats.

  American journal of physiology. Renal physiology 20040101

• Ryanodine receptors in peritoneal mast cells: possible role in the modulation of exocytotic activity.

  Pflugers Archiv : European journal of physiology 20040101

• 60-minute application of S-Caine Peel prior to 1,064 nm long-pulsed Nd:YAG laser treatment of leg veins.

  Lasers in surgery and medicine 20040101

• Addition of epinephrine to intrathecal tetracaine augments depression of the bispectral index during intraoperative propofol sedation.

  Journal of anesthesia 20040101

• Development of the bioadhesive tetracaine gels for enhanced local anesthetic effects.

  Drug development and industrial pharmacy 20040101

• Perineal allergic contact dermatitis due to tetracaine in a urological lubricant.

  Contact dermatitis 20040101

• [Studies for analyzing prohibited ingredients such as tetracaine hydrochloride in cosmetics].

  Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20040101

• A randomized controlled trial evaluating the efficacy of tetracaine gel for pain relief from peripherally inserted central catheters in infants.

  Advances in neonatal care : official journal of the National Association of Neonatal Nurses 20031201

• Topical tetracaine prior to arterial puncture: a randomized, placebo-controlled clinical trial.

  Respiratory medicine 20031101

• Elevated sarcoplasmic reticulum Ca2+ leak in intact ventricular myocytes from rabbits in heart failure.

  Circulation research 20031003

• Thirty-minute application of the S-Caine peel prior to nonablative laser treatment.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20031001

• Two randomized, double-blind, placebo-controlled studies evaluating the S-Caine Peel for induction of local anesthesia before long-pulsed Nd:YAG laser therapy for leg veins.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20031001

• Randomized trial of novel tetracaine patch to provide local anaesthesia in neonates undergoing venepuncture.

  British journal of anaesthesia 20031001

• Amethocaine or ketorolac eyedrops provide inadequate analgesia in pediatric strabismus surgery.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031001

• [A case of emergency surgery in a patient with bronchial asthma under continuous spinal anesthesia].

  Masui. The Japanese journal of anesthesiology 20031001

• Catanionic drug-surfactant mixtures: phase behavior and sustained release from gels.

  Pharmaceutical research 20031001

• [Spinal anesthesia using hyperbaric bupivacaine HCl for cesarean section].

  Masui. The Japanese journal of anesthesiology 20030901

• [Tetracaine drops versus lidocaine gel for topical anaesthesia in cataract surgery].

  Klinische Monatsblatter fur Augenheilkunde 20030901

• Lipid-protein interactions and effect of local anesthetics in acetylcholine receptor-rich membranes from Torpedo marmorata electric organ.

  Biochemistry 20030805

• Lidocaine attenuates cytokine-induced cell injury in endothelial and vascular smooth muscle cells.

  Anesthesia and analgesia 20030801

• A comparison of the neurotoxic effects on the spinal cord of tetracaine, lidocaine, bupivacaine, and ropivacaine administered intrathecally in rabbits.

  Anesthesia and analgesia 20030801

• Pediatric wound triage protocols.

  Annals of emergency medicine 20030701

• Application of topical local anesthetic at triage reduces treatment time for children with lacerations: a randomized controlled trial.

  Annals of emergency medicine 20030701

• Bye-bye benzocaine?

  Nursing 20030701

• Comparison of lidocaine 2% gel versus amethocaine as the sole anesthetic agent for strabismus surgery.

  Ophthalmology 20030701

• Mechanisms underlying combined action of clonidine and local anesthetics.

  Bulletin of experimental biology and medicine 20030701

• Determination of cetylpyridinium chloride and tetracaine hydrochloride in buccal tablets by RP-HPLC.

  Journal of pharmaceutical and biomedical analysis 20030601

• A prospective, randomized, double-blind comparison of buffered versus plain tetracaine in reducing the pain of topical ophthalmic anesthesia.

  Annals of emergency medicine 20030601

• Extended lifetime of reagentless detector for multiple inhibitors of acetylcholinesterase.

  Biosensors & bioelectronics 20030501

• Effects of tetracaine and bupivacaine on chemiluminescence generated by formyl-methionyl-leucyl-phenylalanine-stimulated human leukocytes and cell-free systems.

  International immunopharmacology 20030501

• Formulation and efficacy studies of new topical anesthetic creams.

  Drug development and industrial pharmacy 20030501

• Recurrent neurological symptoms in a patient after repeat combined spinal and epidural anaesthesia.

  British journal of anaesthesia 20030301

• Saddle block using 10-20% tetracaine for patients with perineal pain due to recurrent rectal cancer.

  Anesthesiology 20030301

• Toxicity of local anaesthetics.

  Best practice & research. Clinical anaesthesiology 20030301

• Clinical study of patient-controlled epidural analgesia with tetracaine hydrochloride after pulmonary lobectomy.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20030301

• Synaptic activity modifies the levels of Dorsal and Cactus at the neuromuscular junction of Drosophila.

  Journal of neurobiology 20030215

• Differential effects of courtship and mating on receptivity and brain metabolism in female red-sided garter snakes (Thamnophis sirtalis parietalis).

  Behavioral neuroscience 20030201

• A multiply charged tetracaine derivative blocks cyclic nucleotide-gated channels at subnanomolar concentrations.

  Biochemistry 20030121

• Haemodynamic changes during high spinal anaesthesia in children having open heart surgery.

  Paediatric anaesthesia 20030101

• Local anesthetics induce human renal cell apoptosis.

  American journal of nephrology 20030101

• Local anaesthetic effects and toxicity of seven new diethanolamine and morpholine derivatives of fomocaine. Testing in rats compared with procaine and tetracaine.

  Arzneimittel-Forschung 20030101

• [Use of 2% anilocaine solution for injections in ophthalmology].

  Vestnik oftalmologii 20030101

• Comparison of hemodynamic and anesthetic effects of hyperbaric bupivacaine and tetracaine in spinal anesthesia.

  Journal of anesthesia 20030101

• The tertiary amine local anesthetic dibucaine binds to the membrane skeletal protein spectrin.

  FEBS letters 20021218

• Depressed ryanodine receptor activity increases variability and duration of the systolic Ca2+ transient in rat ventricular myocytes.

  Circulation research 20021004

• Quantitative assessment of the SR Ca2+ leak-load relationship.

  Circulation research 20021004

• Sarcoplasmic reticulum calcium load regulates rat arterial smooth muscle calcium sparks and transient K(Ca) currents.

  The Journal of physiology 20021001

• A randomized controlled trial of the effectiveness of topical amethocaine in reducing pain during arterial puncture.

  Chest 20021001

• Effects of euthanasia on brain physiological activities monitored in real-time.

  Neurological research 20021001

• Blood investigation in a fatality involving the veterinary drug T-61.

  Journal of analytical toxicology 20021001

• Effective topical anesthetic agents and techniques.

  Dental clinics of North America 20021001

• Oral mucositis--current concepts and management.

  Annals of the Royal Australasian College of Dental Surgeons 20021001

• Calcium-induced calcium release and cyclic ADP-ribose-mediated signaling in the myocytes from small coronary arteries.

  Microvascular research 20020901

• Is cocaine needed in topical anaesthesia?

  Emergency medicine journal : EMJ 20020901

• [Spinal anesthesia in premature infants--indications, technical aspects and results].

  Harefuah 20020901

• Combined spinal and epidural anesthesia for abdominal aortic aneurysm surgery in patients with severe chronic pulmonary obstructive disease.

  International angiology : a journal of the International Union of Angiology 20020901

• Amphiphilic effects of local anesthetics on rotational mobility in neuronal and model membranes.

  Biochimica et biophysica acta 20020819

• Non-preserved 1% lidocaine solution has less antibacterial properties than currently available anaesthetic eye-drops.

  Current eye research 20020801

• Allosterically linked noncompetitive antagonist binding sites in the resting nicotinic acetylcholine receptor ion channel.

  Archives of biochemistry and biophysics 20020701

• The inhibitory effect of local anesthetics on bradykinin-induced phospholipase D activation in rat pheochromocytoma PC12 cells.

  Anesthesia and analgesia 20020701

• Principles of office anesthesia: part II. Topical anesthesia.

  American family physician 20020701

• Agonist-induced phasic and tonic responses in smooth muscle are mediated by InsP(3).

  Journal of cell science 20020515

• Reagent-less detection of a competitive inhibitor of immobilized acetylcholinesterase.

  Biosensors & bioelectronics 20020501

• Involvement of the mitogen-activated protein kinase family in tetracaine-induced PC12 cell death.

  Anesthesiology 20020501

• The effect of baricity of intrathecal morphine in children receiving tetracaine spinal anaesthesia for cardiac surgery: a preliminary report.

  Paediatric anaesthesia 20020501

• A laser-clinic nurse with allergic contact dermatitis from tetracaine.

  Contact dermatitis 20020501

• Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children.

  The Annals of pharmacotherapy 20020401

• Radial artery cannulation: topical amethocaine gel versus lidocaine infiltration.

  British journal of anaesthesia 20020401

• Bupivacaine, but not tetracaine, protects against the in vitro ischemic insult of rat hippocampal CA1 neurons.

  Neuroscience research 20020301

• The inhibition of the N-methyl-D-aspartate receptor channel by local anesthetics in mouse CA1 pyramidal neurons.

  Anesthesia and analgesia 20020201

• Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells.

  Clinical and experimental immunology 20020201

• Intercostal nerve block with 5% tetracaine for chronic pain syndromes.

  Journal of clinical anesthesia 20020201

• Amethocaine-lidocaine cream, a new topical formulation for preventing venopuncture-induced pain in children.

  Regional anesthesia and pain medicine 20020101

• [Characteristics of functioning of electromechanical coupling in striated muscles of higher and lower vertebrates].

  Biofizika 20020101

• Corneal complications following abuse of topical anesthetics.

  European journal of ophthalmology 20020101

• [Manufacture of tetracaine hydrochloride tablets using direct compression and moist granulation].

  Vojnosanitetski pregled 20020101

• Distribution of tetracaine and its metabolite in rabbits after high versus normal spinal anesthesia.

  Forensic science international 20011227

• Local anesthetics noncompetitively inhibit function of four distinct nicotinic acetylcholine receptor subtypes.

  The Journal of pharmacology and experimental therapeutics 20011201

• Inhibition of wild-type and mutant neuronal nicotinic acetylcholine receptors by local anesthetics.

  Molecular pharmacology 20011201

• Role of the bandage soft contact lens in the postoperative laser in situ keratomileusis patient.

  Journal of cataract and refractive surgery 20011201

• High-concentration tetracaine for the management of trigeminal neuralgia: quantitative assessment of sensory function after peripheral nerve block.

  The Clinical journal of pain 20011201

• Allergic contact dermatitis from local anaesthetic on peristomal skin.

  Contact dermatitis 20011201

• Topical anesthetics update: EMLA and beyond.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20011201

• Cauda equina syndrome after spinal tetracaine: electromyographic evaluation--20 years follow-up.

  Anesthesiology 20011101

• Ouabain stimulates unidirectional and net potassium efflux in resting mammalian skeletal muscle.

  Canadian journal of physiology and pharmacology 20011101

• UV-spectrophotometry study of membrane transport processes with a novel diffusion cell.

  International journal of pharmaceutics 20011023

• Calcium waves induced by hypertonic solutions in intact frog skeletal muscle fibres.

  The Journal of physiology 20011015

• The addition of epinephrine to tetracaine injected intrathecally sustains an increase in glutamate concentrations in the cerebrospinal fluid and worsens neuronal injury.

  Anesthesia and analgesia 20011001

• EMLA or Ametop, and for how long?

  Anaesthesia 20011001

• Allergic contact dermatitis to proparacaine with subsequent cross-sensitization to tetracaine from ophthalmic preparations.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20010901

• Phospholipase A(2) in rabbit tears: a host defense against Staphylococcus aureus.

  Investigative ophthalmology & visual science 20010901

• Role of airway receptors in altitude-induced dyspnea.

  Medicine and science in sports and exercise 20010901

• Topical anesthesia--a new approach to cataract surgery.

  AORN journal 20010901

• Tetracaine topical anesthesia for myringotomy.

  The Laryngoscope 20010901

• Direct neurotoxicity of tetracaine on growth cones and neurites of growing neurons in vitro.

  Anesthesiology 20010901

• Dynamic regulation of sarcoplasmic reticulum Ca(2+) content and release by luminal Ca(2+)-sensitive leak in rat ventricular myocytes.

  Biophysical journal 20010801

• [Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)].

  Archivos de la Sociedad Espanola de Oftalmologia 20010801

• Topical anesthetics in children: agents and techniques that equally comfort patients, parents, and clinicians.

  Current opinion in pediatrics 20010801

• Spinal anesthesia with tetracaine in 7.5% or 0.75% glucose in adolescents and adults.

  Anesthesia and analgesia 20010701

• A comparison of the effects of ATP and tetracaine on spontaneous Ca(2+) release from rat permeabilised cardiac myocytes.

  The Journal of physiology 20010701

• Interactions between 3-(Trifluoromethyl)-3-(m-[(125)I]iodophenyl)diazirine and tetracaine, phencyclidine, or histrionicotoxin in the Torpedo series nicotinic acetylcholine receptor ion channel.

  Molecular pharmacology 20010601

• Temporary inactivation of the retrosplenial cortex causes a transient reorganization of spatial coding in the hippocampus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601

• Effects of local anesthetics on the contractility of rat bladders.

  The Journal of urology 20010601

• Local anesthetic inhibition of voltage-activated potassium currents in rat dorsal root ganglion neurons.

  Anesthesiology 20010601

• A prospective multicenter trial to determine the incidence of transient neurologic symptoms after spinal anesthesia with phenylephrine added to 0.5% tetracaine.

  Hiroshima journal of medical sciences 20010601

• Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. EMLA or amethocaine (tetracaine) for topical analgesia in children.

  Emergency medicine journal : EMJ 20010501

• No more tears: a randomized controlled double-blind trial of Amethocaine gel vs. placebo in the management of procedural pain in neonates.

  Journal of advanced nursing 20010501

• A randomised, double-blind, placebo-controlled, comparative study of topical skin analgesics and the anxiety and discomfort associated with venous cannulation.

  British dental journal 20010428

• Charge movements in intact amphibian skeletal muscle fibres in the presence of cardiac glycosides.

  The Journal of physiology 20010415

• The clinical use of small-dose tetracaine spinal anesthesia for transurethral prostatectomy.

  Anesthesia and analgesia 20010401

• The effect of conduction block on the spinal release of immunoreactive-neuropeptide Y (ir-NPY) in the neuropathic rat.

  Pain 20010401

• Resident's column: Use of topical anesthetics in children.

  Pediatric annals 20010401

• Differential effects of airway anesthesia on ozone-induced pulmonary responses in human subjects.

  American journal of respiratory and critical care medicine 20010401

• Ametop gel and suture removal.

  British journal of plastic surgery 20010301

• Endoscopic carbon dioxide laser turbinoplasty.

  The Journal of laryngology and otology 20010301

• Corneal sensation after topical anesthesia.

  Cornea 20010301

• Topical anesthesia for cataract surgery: a population-based perspective.

  Journal of cataract and refractive surgery 20010301

• Local anesthetic-induced microscopic and mesoscopic effects in micelles. A fluorescence, spin label and SAXS study. Single angle X-ray scattering.

  Biochimica et biophysica acta 20010209

• Blood concentrations of tetracaine and its metabolite following spinal anesthesia.

  Forensic science international 20010201

• Topical anesthesia for phacoemulsification and painless subconjunctival antibiotic injection.

  Journal of cataract and refractive surgery 20010201

• Topical amethocaine gel for pain relief of heel prick blood sampling: a randomised double blind controlled trial.

  Archives of disease in childhood. Fetal and neonatal edition 20010101

• The effect of dexamethasone on postoperative pain and emesis after intrathecal neostigmine.

  Anesthesia and analgesia 20010101

• Insecticidal activity of common reagents for insect foreign bodies of the ear.

  The Laryngoscope 20010101

• Effect of tetracaine chlorhydrate on the mechanical properties of the erythrocyte membrane.

  Blood cells, molecules & diseases 20010101

• Pain management for neonatal circumcision.

  Paediatric drugs 20010101

• Redox properties of local anesthetics: A structural determinant of closed channel blockers in BTX-modified Na+ channels.

  Membrane & cell biology 20010101

• Comparison of HPLC and GC-MS methods for determination of embutramide (a component of Tanax or T-61) in biological specimens.

  Journal of analytical toxicology 20010101

• Simultaneous determination of mepivacaine, tetracaine, and p-butylaminobenzoic acid by high-performance liquid chromatography.

  Journal of pharmacological and toxicological methods 20010101

• Potential neurotoxicity of spinal anesthesia with lidocaine.

  Mayo Clinic proceedings 20000901

• Unexpected recurrent seizures following repeated spinal injections of tetracaine--a case report.

  Acta anaesthesiologica Sinica 20000601

• Nitric oxide synthesis inhibition modifies the cardiotoxicity of tetracaine and lidocaine.

  Anesthesia and analgesia 19990401

• Apnea following spinal anaesthesia in two former pre-term infants.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 19981001

• The recovery profile of hyperbaric spinal anesthesia with lidocaine, tetracaine, and bupivacaine.

  Regional anesthesia and pain medicine 19980101

• Treatment of hypotension after hyperbaric tetracaine spinal anesthesia.

  Anesthesiology 19971101

• Treatment of hypotension after hyperbaric tetracaine spinal anesthesia. A randomized, double-blind, cross-over comparison of phenylephrine and epinephrine.

  Anesthesiology 19970401

• Conus medullaris injury following both tetracaine and lidocaine spinal anesthesia.

  Journal of clinical anesthesia 19961201

• Intrathecal hyperbaric 0.5% tetracaine as a possible cause of transient neurologic toxicity.

  Anesthesia and analgesia 19960501

• Persistent sacral sensory deficit induced by intrathecal local anesthetic infusion in the rat.

  Anesthesiology 19940401

• Urethral stricture following transurethral resection of the prostate. The role of local anaesthetics.

  British journal of urology 19931201

• A single exposure to cocaine or immobilization stress provides extremely long-lasting, selective protection against sudden cardiac death from tetracaine.

  Life sciences 19890101

• Recurrent seizures following mucosal application of TAC.

  Annals of emergency medicine 19880601

• [Acute poisoning by tetracaine following topical oropharyngeal administration].

  Revista espanola de anestesiologia y reanimacion 19880101

• Comparative CNS toxicity of lidocaine, etidocaine, bupivacaine, and tetracaine in awake dogs following rapid intravenous administration.

  Anesthesia and analgesia 19830401

• Survival following 1000 mg of amethocaine.

  British journal of anaesthesia 19790501

• Central-nervous-system toxicity of local anesthetic mixtures in monkeys.

  Anesthesiology 19770301

• Transient iatrogenic transverse myelitis.

  Anaesthesia 19770101

• [Use of plasmion in the correction of possible hypovolemia after peridural anesthesia, neuroleptanalgesia and alfatesine anesthesia].

  Anesthesie, analgesie, reanimation 19760101

• [A case of clinical death caused by dicaine sensitivity].

  Khirurgiia 19700101

• Keratitis from misuse of corneal anesthetics.

  The New England journal of medicine 19680822