1361019-05-7 | 3,5-Dibromo-1-methyl-1h-pyrazole

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$12.00	$9.00
250mg	97%	in stock	$22.00	$15.00
1g	97%	in stock	$32.00	$22.00
5g	97%	in stock	$99.00	$69.00
25g	97%	in stock	$446.00	$312.00

Description

• Catalog Number: AY12681
• Chemical Name: 3,5-Dibromo-1-methyl-1h-pyrazole
• CAS Number: 1361019-05-7
• Molecular Formula: C4H4Br2N2
• Molecular Weight: 239.896
• MDL Number: MFCD28399417
• SMILES: Brc1cc(n(n1)C)Br

Upstream Synthesis Route

To synthesize 3,5-Dibromo-1-methyl-1H-pyrazole from commercially available starting materials, follow the steps outlined below:

Step 1: Synthesis of 1-Methylpyrazole
Begin with the condensation of acetylacetone with methylhydrazine. Acetylacetone (3-oxobutan-2-one) reacts with methylhydrazine in an acid-catalyzed environment to produce 1-methylpyrazole. Typically, an acidic medium like hydrochloric acid can be used to facilitate the condensation reaction.

Step 2: Bromination
Subject the 1-methylpyrazole to bromination using elemental bromine (Br2) in a solvent like dichloromethane. The reaction is usually done in the presence of a catalytic amount of an acid, such as ferric bromide (FeBr3), which acts as a Lewis acid to facilitate the electrophilic substitution of hydrogen atoms with bromine atoms on the 3 and 5 positions of the pyrazole ring.

Ensure all steps are conducted under controlled conditions appropriate for the reactivity of the reagents and sensitivity of the intermediates. This synthesis route is expected to yield 3,5-dibromo-1-methyl-1H-pyrazole, which should then be purified by standard methods (e.g., recrystallization or column chromatography) to attain the desired level of purity for subsequent applications.