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Agomelatine: mechanism of action and pharmacological profile in relation to antidepressant properties.
British journal of pharmacology 20140801
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Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors.
Bioorganic & medicinal chemistry letters 20130115
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Cardiovascular effects of melatonin receptor agonists.
Expert opinion on investigational drugs 20121101
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Circadian rhythms in obsessive-compulsive disorder.
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Role of melatonin in mood disorders and the antidepressant effects of agomelatine.
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Agomelatine may improve REM sleep behavior disorder symptoms.
Journal of clinical psychopharmacology 20121001
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Melatonin and synthetic melatonergic agonists: actions and metabolism in the central nervous system.
Central nervous system agents in medicinal chemistry 20120901
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Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease.
Menopause (New York, N.Y.) 20120801
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Agomelatine treatment with adolescents with ADHD.
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Agomelatine versus venlafaxine XR in the treatment of anhedonia in major depressive disorder: a pilot study.
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(1-{[2-(6-Methoxynaphthalen-1-yl)ethyl]amino}ethylidene)oxidanium bromide monohydrate.
Acta crystallographica. Section C, Crystal structure communications 20120801
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Agomelatine for the treatment of posttraumatic stress disorder: a case report.
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20120801
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The antidepressant agomelatine inhibits stress-mediated changes in amino acid efflux in the rat hippocampus and amygdala.
Brain research 20120723
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Anticonvulsant effects of agomelatine in mice.
Epilepsy & behavior : E&B 20120701
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Agomelatine prevents relapse in generalized anxiety disorder: a 6-month randomized, double-blind, placebo-controlled discontinuation study.
The Journal of clinical psychiatry 20120701
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Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC.
Psychopharmacology 20120601
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Agomelatine-induced akathisia with concomitant duloxetine medication: a case report.
Pharmacopsychiatry 20120601
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Melatonin and its analogs in insomnia and depression.
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Treating ADHD with agomelatine.
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The long-term abnormalities in circadian expression of Period 1 and Period 2 genes in response to stress is normalized by agomelatine administered immediately after exposure.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120301
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Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I).
European journal of medicinal chemistry 20120301
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Emerging drugs for major depressive disorder.
Expert opinion on emerging drugs 20120301
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Melatonergic drugs for therapeutic use in insomnia and sleep disturbances of mood disorders.
CNS & neurological disorders drug targets 20120301
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Agomelatine and the brave old world of narrative-based medicine.
Evidence-based mental health 20120201
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Agomelatine suppresses locomotor hyperactivity in olfactory bulbectomised rats: a comparison to melatonin and to the 5-HT(2c) antagonist, S32006.
European journal of pharmacology 20120105
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Agomelatine improves sleep in a patient with fatal familial insomnia.
Pharmacopsychiatry 20120101
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CNS drugs 20120101
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Validated LC-MS/MS method for quantification of agomelatine in human plasma and its application in a pharmacokinetic study.
Journal of mass spectrometry : JMS 20120101
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Emerging targets for the pharmacological treatment of depression: focus on melatonergic system.
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Neuropsychiatric disease and treatment 20120101
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Agomelatine: an antidepressant without deterioration of sexual response.
Journal of sex & marital therapy 20120101
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Translatability scoring in drug development: eight case studies.
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Mens sana monographs 20120101
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Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101
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Inflammation-related disorders in the tryptophan catabolite pathway in depression and somatization.
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Synergistic mechanisms involved in the antidepressant effects of agomelatine.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120101
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Circadian dimension and severity of depression.
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Onset, time course and trajectories of improvement with antidepressants.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120101
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Anhedonia and major depression: the role of agomelatine.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120101
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Relief of intractable posthypoxic myoclonus after administration of agomelatine.
Clinical neuropharmacology 20120101
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Agomelatine augmentation of escitalopram therapy in treatment-resistant obsessive-compulsive disorder: a case report.
Case reports in psychiatry 20120101
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Toward the definition of stereochemical requirements for MT2-selective antagonists and partial agonists by studying 4-phenyl-2-propionamidotetralin derivatives.
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Melatonin receptor agonists: new options for insomnia and depression treatment.
CNS neuroscience & therapeutics 20111201
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Chronic agomelatine and fluoxetine induce antidepressant-like effects in H/Rouen mice, a genetic mouse model of depression.
Pharmacology, biochemistry, and behavior 20111201
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Mode of action of agomelatine: synergy between melatonergic and 5-HT2C receptors.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20111201
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Could the underestimation of bipolarity obstruct the search for novel antidepressant drugs?
Expert opinion on pharmacotherapy 20111201
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The effects of agomelatine on sexual function in depressed patients and healthy volunteers.
Human psychopharmacology 20111201
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Efficacy of antidepressants for late-life depression: a meta-analysis and meta-regression of placebo-controlled randomized trials.
The Journal of clinical psychiatry 20111201
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Pharmacotherapy of anxiety disorders: a critical review.
Dialogues in clinical neuroscience 20111201
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The influence of melatonin and agomelatine on urodynamic parameters in experimental overactive bladder model--preliminary results.
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Nature reviews. Drug discovery 20111031
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Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats.
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N-Acetyl-5-arylalkoxytryptamine analogs: probing the melatonin receptors for MT(1) -selectivity.
Archiv der Pharmazie 20111001
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Expert opinion on pharmacotherapy 20111001
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Agomelatine: protecting the CNS from the effects of stress.
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Agomelatine facilitates positive versus negative affective processing in healthy volunteer models.
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Comparison of agomelatine and escitalopram on nighttime sleep and daytime condition and efficacy in major depressive disorder patients.
International clinical psychopharmacology 20110901
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A benefit-risk assessment of agomelatine in the treatment of major depression.
Drug safety 20110901
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Agomelatine: a narrative review.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110901
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Publication bias and outcome reporting bias: agomelatine as a case example.
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A consensus statement for safety monitoring guidelines of treatments for major depressive disorder.
The Australian and New Zealand journal of psychiatry 20110901
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Chronotherapeutics and psychiatry: setting the clock to relieve the symptoms.
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Therapeutic potential of melatonin and its analogs in Parkinson's disease: focus on sleep and neuroprotection.
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Lancet (London, England) 20110813
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The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors.
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7-Meth-oxy-3,4-dihydro-naphthalen-1(2H)-one.
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[The effects of antidepressants on sleep in depressed patients with particular reference to trazodone in comparison to agomelatine, amitriptyline, doxepin, mianserine and mirtazapine].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20110701
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Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat.
Pharmacology, biochemistry, and behavior 20110601
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Melatonin agonists in primary insomnia and depression-associated insomnia: are they superior to sedative-hypnotics?
Progress in neuro-psychopharmacology & biological psychiatry 20110601
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Neurochemical and neuropharmacological aspects of circadian disruptions: an introduction to asynchronization.
Current neuropharmacology 20110601
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Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine.
Psychopharmacology 20110501
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Focus on agomelatine.
Current medical research and opinion 20110401
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Efficacy of antidepressants for dysthymia: a meta-analysis of placebo-controlled randomized trials.
The Journal of clinical psychiatry 20110401
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Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress.
Behavioural brain research 20110317
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Cartesian theories on the passions, the pineal gland and the pathogenesis of affective disorders: an early forerunner.
Psychological medicine 20110301
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Agomelatine as chronopsychopharmaceutics restoring circadian rhythms and enhancing resilience to stress: a wishfull thinking or an innovative strategy for superior management of depression?
Psychiatria Danubina 20110301
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Hormone treatment of depression.
Dialogues in clinical neuroscience 20110301
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Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands.
Bioorganic & medicinal chemistry letters 20110215
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CNS & neurological disorders drug targets 20110201
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Agomelatine in the treatment of panic disorder.
Progress in neuro-psychopharmacology & biological psychiatry 20110115
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Melatonin and its agonist ramelteon in Alzheimer's disease: possible therapeutic value.
International journal of Alzheimer's disease 20110101
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The societal costs of insomnia.
Neuropsychiatric disease and treatment 20110101
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Switching from serotonin reuptake inhibitors to agomelatine in patients with refractory obsessive-compulsive disorder: a 3 month follow-up case series.
Annals of general psychiatry 20110101
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Melatonin and the metabolic syndrome: physiopathologic and therapeutical implications.
Neuroendocrinology 20110101
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Major depressive disorder, anhedonia and agomelatine: an open-label study.
Journal of biological regulators and homeostatic agents 20110101
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Class effect of pharmacotherapy in bipolar disorder: fact or misbelief?
Annals of general psychiatry 20110101
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Circadian rhythms, melatonin and depression.
Current pharmaceutical design 20110101
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The Clinical Global Impression Scale and the influence of patient or staff perspective on outcome.
BMC psychiatry 20110101
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Melatonin in mitochondrial dysfunction and related disorders.
International journal of Alzheimer's disease 20110101
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Efficacy of duloxetine and agomelatine does not exceed that of other antidepressants in patients with autistic disorder: preliminary results in 3 patients.
The primary care companion for CNS disorders 20110101
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Influence of Pre-Training Predator Stress on the Expression of c-fos mRNA in the Hippocampus, Amygdala, and Striatum Following Long-Term Spatial Memory Retrieval.
Frontiers in behavioral neuroscience 20110101
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Is circadian rhythm disruption important in obsessive-compulsive disorder (OCD)? A case of successful augmentation with agomelatine for the treatment of OCD.
Clinical neuropharmacology 20110101
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Disruption of circadian rhythms: a crucial factor in the etiology of depression.
Depression research and treatment 20110101
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[Melatoninergic antidepressant valdoxan].
Eksperimental'naia i klinicheskaia farmakologiia 20110101
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Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence.
PloS one 20110101
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Illuminating the deleterious effects of light at night.
F1000 medicine reports 20110101
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[Possibilities of preventive treatment of migraine with the MT1- and MT2 agonist and 5-HT2с receptor antagonist agomelatin (valdoxan)].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101
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Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.
PloS one 20110101
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Disrupted chronobiology of sleep and cytoprotection in obesity: possible therapeutic value of melatonin.
Neuro endocrinology letters 20110101
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Diazepam discontinuation through agomelatine in schizophrenia with insomnia and depression.
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Effect of agomelatine and its interaction with the daily corticosterone rhythm on progenitor cell proliferation in the dentate gyrus of the adult rat.
Neuropharmacology 20101101
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Superior antidepressant efficacy results of agomelatine versus fluoxetine in severe MDD patients: a randomized, double-blind study.
International clinical psychopharmacology 20101101
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A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation.
Current neuropharmacology 20100901
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The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats.
CNS neuroscience & therapeutics 20100801
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Nature reviews. Drug discovery 20100801
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Restoring circadian rhythms: a new way to successfully manage depression.
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The antidepressant agomelatine improves the quality of life of depressed patients: implications for remission.
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The importance of early symptom relief in antidepressant treatment: focus on agomelatine.
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Drug and therapeutics bulletin 20100801
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Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice.
The international journal of neuropsychopharmacology 20100701
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Dialogues in clinical neuroscience 20100601
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Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands.
Bioorganic & medicinal chemistry 20100515
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A randomized double-blind placebo-controlled trial of treatment as usual plus exogenous slow-release melatonin (6 mg) or placebo for sleep disturbance and depressed mood.
International clinical psychopharmacology 20100501
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Australian family physician 20100501
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Impact of the novel antidepressant agomelatine on disturbed sleep-wake cycles in depressed patients.
Human psychopharmacology 20100401
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MMW Fortschritte der Medizin 20100311
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Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration.
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Human psychopharmacology 20100301
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Expert review of neurotherapeutics 20100201
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Better sexual acceptability of agomelatine (25 and 50 mg) compared with paroxetine (20 mg) in healthy male volunteers. An 8-week, placebo-controlled study using the PRSEXDQ-SALSEX scale.
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PloS one 20100101
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Molecular brain 20100101
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The emerging modern face of mood disorders: a didactic editorial with a detailed presentation of data and definitions.
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Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways.
BMC neuroscience 20100101
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Frontiers in systems neuroscience 20100101
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Frontiers in molecular neuroscience 20100101
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Techniques for studying inverse agonist activity of antidepressants at recombinant nonedited 5-HT(₂C-INI) receptor and native neuronal 5-HT(₂C) receptors.
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Prescrire international 20091201
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Dialogues in clinical neuroscience 20080601
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20080401
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Jet lag: therapeutic use of melatonin and possible application of melatonin analogs.
Travel medicine and infectious disease 20080101
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Melatonergic drugs in clinical practice.
Arzneimittel-Forschung 20080101
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Agomelatine: AGO 178, AGO178, S 20098.
Drugs in R&D 20080101
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Melatonin receptor agonists: SAR and applications to the treatment of sleep-wake disorders.
Current topics in medicinal chemistry 20080101
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Non-REM sleep instability in patients with major depressive disorder: subjective improvement and improvement of non-REM sleep instability with treatment (Agomelatine).
Sleep medicine 20071201
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A review of the efficacy and tolerability of agomelatine in the treatment of major depression.
Expert opinion on investigational drugs 20071201
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Agomelatine: a novel atypical antidepressant.
Journal of psychosocial nursing and mental health services 20071201
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Improvement in subjective sleep in major depressive disorder with a novel antidepressant, agomelatine: randomized, double-blind comparison with venlafaxine.
The Journal of clinical psychiatry 20071101
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Major depressive disorder, sleep EEG and agomelatine: an open-label study.
The international journal of neuropsychopharmacology 20071001
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Efficacy of agomelatine, a MT1/MT2 receptor agonist with 5-HT2C antagonistic properties, in major depressive disorder.
The international journal of neuropsychopharmacology 20071001
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Evidence of agomelatine's antidepressant efficacy: the key points.
International clinical psychopharmacology 20071001
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High-quality remission: potential benefits of the melatonergic approach for patients with major depressive disorder.
International clinical psychopharmacology 20071001
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The interaction between the internal clock and antidepressant efficacy.
International clinical psychopharmacology 20071001
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New antidepressants or more of the same?
Neuropsychiatric disease and treatment 20071001
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[Pharmacotherapy of depression: recent developments].
Revue medicale suisse 20070919
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Severe depression and antidepressants: focus on a pooled analysis of placebo-controlled studies on agomelatine.
International clinical psychopharmacology 20070901
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Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data.
Bipolar disorders 20070901
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The phase shift hypothesis for the circadian component of winter depression.
Dialogues in clinical neuroscience 20070901
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Agomelatine and its therapeutic potential in the depressed patient.
Neuropsychiatric disease and treatment 20070801
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First evidence of melatonin receptors distribution in the suprachiasmatic nucleus of tree shrew brain.
Neuro endocrinology letters 20070601
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20070601
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20070501
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20070401
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Agomelatine in the treatment of seasonal affective disorder.
Psychopharmacology 20070301
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Emerging treatments for major depression.
Expert review of neurotherapeutics 20070201
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[Melatonin, melatonin receptor agonists and tryptophan as sleep aids].
Pharmazie in unserer Zeit 20070101
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Hippocampal neurogenesis, depressive disorders, and antidepressant therapy.
Neural plasticity 20070101
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Role of the melatonin system in the control of sleep: therapeutic implications.
CNS drugs 20070101
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[New hypnotics: perspectives from sleep physiology].
Vertex (Buenos Aires, Argentina) 20070101
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Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model.
Behavioural pharmacology 20061201
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Could agomelatine be the ideal antidepressant?
Expert review of neurotherapeutics 20061101
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[Agomelatine: the first 'melatoninergic' antidepressant].
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20061001
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New directions for drug discovery.
Dialogues in clinical neuroscience 20060901
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Effects of melatonin and agomelatine in anxiety-related procedures in rats: interaction with diazepam.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060801
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Melatonin: Nature's most versatile biological signal?
The FEBS journal 20060701
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Agomelatine targets a range of major depressive disorder symptoms.
Current opinion in investigational drugs (London, England : 2000) 20060701
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Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis.
Biological psychiatry 20060601
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Future prospects in depression research.
Dialogues in clinical neuroscience 20060601
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Treatments in depression.
Dialogues in clinical neuroscience 20060601
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Depression and sleep: pathophysiology and treatment.
Dialogues in clinical neuroscience 20060601
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Homology modelling of the serotoninergic 5-HT2c receptor.
Journal of enzyme inhibition and medicinal chemistry 20060601
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Prospects for the treatment of depression.
The Australian and New Zealand journal of psychiatry 20060501
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Placebo-controlled trial of agomelatine in the treatment of major depressive disorder.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060201
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Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety.
Behavioural pharmacology 20060201
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Why do we need new and better antidepressants?
International clinical psychopharmacology 20060201
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Biological rhythm disturbances in mood disorders.
International clinical psychopharmacology 20060201
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Pharmacology of a new antidepressant: benefit of the implication of the melatonergic system.
International clinical psychopharmacology 20060201
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Clinical efficacy of agomelatine in depression: the evidence.
International clinical psychopharmacology 20060201
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Sleep disturbances and depression: a challenge for antidepressants.
International clinical psychopharmacology 20060201
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Efficacy and tolerance profile of agomelatine and practical use in depressed patients.
International clinical psychopharmacology 20060201
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Therapeutic potential of melatonin ligands.
Chronobiology international 20060101
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Agomelatine: a preliminary review of a new antidepressant.
CNS drugs 20060101
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Antidepressant-like effects of agomelatine, melatonin and the NK1 receptor antagonist GR205171 in impulsive-related behaviour in rats.
Psychopharmacology 20051001
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Anxiolytic-like action of the antidepressant agomelatine (S 20098) after a social defeat requires the integrity of the SCN.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20051001
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[Development of a new antidepressant : agomelatine].
Medecine sciences : M/S 20051001
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Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men.
Clinical endocrinology 20050901
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Antidepressant action of agomelatine (S 20098) in a transgenic mouse model.
Progress in neuro-psychopharmacology & biological psychiatry 20050701
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Recent advances in melatonin receptor ligands.
Archiv der Pharmazie 20050601
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Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade.
Psychopharmacology 20050201
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Newer treatment studies for bipolar depression.
Bipolar disorders 20050101
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[Depression and neuroplasticity: implication of serotoninergic systems].
Therapie 20050101
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RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line.
Cancer letters 20041208
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Melatonin, sleep, and circadian rhythms: rationale for development of specific melatonin agonists.
Sleep medicine 20041101
-
Absence of discontinuation symptoms with agomelatine and occurrence of discontinuation symptoms with paroxetine: a randomized, double-blind, placebo-controlled discontinuation study.
International clinical psychopharmacology 20040901
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Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain.
Neuropharmacology 20040901
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Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: involvement of melatonin and serotonin receptors.
Journal of psychiatry & neuroscience : JPN 20040301
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Chronobiology and mood disorders.
Dialogues in clinical neuroscience 20031201
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Treatment of seasonal affective disorders.
Dialogues in clinical neuroscience 20031201
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20031101
-
Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats.
Psychopharmacology 20031001
-
The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways.
The Journal of pharmacology and experimental therapeutics 20030901
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New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Naunyn-Schmiedeberg's archives of pharmacology 20030601
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Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401
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Effect of agomelatine in the chronic mild stress model of depression in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030401
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Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands.
Journal of medicinal chemistry 20030327
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Gateways to clinical trials. March 2003.
Methods and findings in experimental and clinical pharmacology 20030301
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[Pilot study comparing in blind the therapeutic effect of two doses of agomelatine, melatonin- agonist and selective 5HT2c receptors antagonist, in the treatment of major depressive disorders].
L'Encephale 20030101
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Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT(2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study.
International clinical psychopharmacology 20020901
-
Gateways to Clinical Trials.
Methods and findings in experimental and clinical pharmacology 20020901
-
[Pilot study comparing in blind the therapeutic effect of two doses of agomelatine, melatoninergic agonist and selective 5HT2C receptors antagonist, in the treatment of major depressive disorders].
L'Encephale 20020101
-
S20098 affects the free-running rhythms of body temperature and activity and decreases light-induced phase delays of circadian rhythms of the rat.
Chronobiology international 20010901
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Melatonin or a melatonin agonist corrects age-related changes in circadian response to environmental stimulus.
American journal of physiology. Regulatory, integrative and comparative physiology 20010501
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Serine residues 110 and 114 are required for agonist binding but not antagonist binding to the melatonin MT(1) receptor.
Biochemical and biophysical research communications 20010420
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Evidence of melatonin involvement in pindolol-induced suppression of REM sleep.
Journal of neural transmission (Vienna, Austria : 1996) 20010101
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Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors.
Journal of medicinal chemistry 20001102
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GR196429: a nonindolic agonist at high-affinity melatonin receptors.
The Journal of pharmacology and experimental therapeutics 19980601