13850-16-3 | Tormentic acid

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$75.00	$52.00

Description

• Catalog Number: AA58517
• Chemical Name: Tormentic acid
• CAS Number: 13850-16-3
• Molecular Formula: C30H48O5
• Molecular Weight: 488.6991
• MDL Number: MFCD09970923
• SMILES: O[C@@H]1C[C@@]2(C)[C@H](C([C@H]1O)(C)C)CC[C@@]1([C@@H]2CC=C2[C@@]1(C)CC[C@@]1([C@H]2[C@](C)(O)[C@H](C)CC1)C(=O)O)C
• NSC Number: 720893

Computed Properties

• Complexity: 956
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 11
• Heavy Atom Count: 35
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 1
• XLogP3: 5

Literature

• Tormentic acid derivatives: synthesis and apoptotic activity.

  European journal of medicinal chemistry 20121001

• Euscaphic acid isolated from roots of Rosa rugosa inhibits LPS-induced inflammatory responses via TLR4-mediated NF-κB inactivation in RAW 264.7 macrophages.

  Journal of cellular biochemistry 20120601

• [Studies on the chemical constituents of Rubus parvifolius].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110101

• Hepatoprotective effects of Rubus aleaefolius Poir. and identification of its active constituents.

  Journal of ethnopharmacology 20100527

• [Studies on the lowering blood sugar substances from agrimony (II)].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100501

• 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches.

  Bioorganic & medicinal chemistry 20100215

• Euscaphic acid, a new hypoglycemic natural product from Folium Eriobotryae.

  Die Pharmazie 20081001

• [Studies on chemical constituents from stem barks of Fraxinus paxiana].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801

• Aldose-reductase- and protein-glycation-inhibitory principles from the whole plant of Duchesnea chrysantha.

  Chemistry & biodiversity 20080201

• Naturally occurring compounds affect glutamatergic neurotransmission in rat brain.

  Neurochemical research 20071101

• [Chemical constituents from root of Actinidia chinensis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

• Ursolic acid: a potent inhibitor of superoxides produced in the cellular system.

  Phytotherapy research : PTR 20070601

• Phytochemical and analgesic activity of extract, fractions and a 19-hydroxyursane-type triterpenoid obtained from Rubus rosaefolius (Rosaceae).

  Biological & pharmaceutical bulletin 20070501

• Ursane triterpenoids inhibit atherosclerosis and xanthoma in LDL receptor knockout mice.

  Cardiovascular drugs and therapy 20061001

• [Studies on the chemical constituents in herb of Ludwigia octovalvis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

• Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects.

  Bioscience, biotechnology, and biochemistry 20040101

• Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice.

  European journal of pharmacology 20021025

• Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases.

  Biochimica et biophysica acta 20020429

• Antimycobacterial plant terpenoids.

  Planta medica 20011101

• [Chemical constituents from the fruit of Rosa bella Rehd. et Wils].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010801

• Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.

  Journal of natural products 19980901

• Anti-HIV triterpene acids from Geum japonicum.

  Journal of natural products 19960701