139264-17-8 | Zolmitriptan

Packsize	Purity	Availability	Price	Discounted Price
1mg	98% by HPLC	in stock	$70.00	$49.00
5mg	≥98%	in stock	$74.00	$52.00
1g	97%	in stock	$90.00	$63.00
5g	97%	in stock	$195.00	$136.00
10g	97%	in stock	$299.00	$209.00
25g	97%	in stock	$535.00	$374.00

Description

• Catalog Number: AA60180
• Chemical Name: Zolmitriptan
• CAS Number: 139264-17-8
• Molecular Formula: C16H21N3O2
• Molecular Weight: 287.3568
• MDL Number: MFCD00871503
• SMILES: CN(CCc1c[nH]c2c1cc(C[C@H]1COC(=O)N1)cc2)C
• NSC Number: 760383

Computed Properties

• Complexity: 375
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 2.2

Literature

• Takotsubo syndrome (or apical ballooning syndrome) secondary to Zolmitriptan.

  American journal of therapeutics 20150101

• Bioequivalence study of 2 orodispersible formulations of zolmitriptan 5 mg in healthy volunteers.

  Arzneimittel-Forschung 20121001

• Pharmacokinetic evaluation of zolmitriptan for the treatment of migraines.

  Expert opinion on drug metabolism & toxicology 20120801

• Rheological evaluation of thermoreversible and mucoadhesive nasal gels of Zolmitriptan.

  European review for medical and pharmacological sciences 20120801

• The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 1.

  Bioorganic & medicinal chemistry letters 20120715

• Quantitative determination of zolmitriptan in rat blood and cerebrospinal fluid by reversed phase HPLC-ESI-MS/MS analysis: application to in vivo preclinical pharmacokinetic study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120715

• [CME 'Takotsubo cardiomyopathy].

  Praxis 20120620

• Fast relief from migraine attacks using fast-disintegrating sublingual zolmitriptan tablets.

  Drug development and industrial pharmacy 20120601

• Frovatriptan versus zolmitriptan for the acute treatment of migraine with aura: a subgroup analysis of a double-blind, randomized, multicenter, Italian study.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120501

• Clinical reasoning: a 62-year-old migraineur with a new kind of headache attacks.

  Neurology 20120221

• [Myocardial infarction after taking zolmitriptan].

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20120201

• Identification, preparation and UHPLC determination of process-related impurity in zolmitriptan.

  Journal of pharmaceutical and biomedical analysis 20120125

• Zolmitriptan-induced acute myocardial infarction.

  Cardiology journal 20120101

• Preparation and evaluation of zolmitriptan submicron emulsion for rapid and effective nasal absorption in beagle dogs.

  Drug development and industrial pharmacy 20111201

• Surface thermodynamics of mucoadhesive dry powder formulation of zolmitriptan.

  AAPS PharmSciTech 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Evaluation of submicron emulsion as vehicles for rapid-onset intranasal delivery and improvement in brain targeting of zolmitriptan.

  Drug delivery 20111101

• Influence of formulation variables in transdermal drug delivery system containing zolmitriptan.

  International journal of pharmaceutics 20111031

• Zolmitriptan induced acute coronary syndrome: a unique case.

  American journal of therapeutics 20110901

• Formulation of zolmitriptan sublingual tablets prepared by direct compression with different polymers: in vitro and in vivo evaluation.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801

• Evolution of paediatric off-label use after new significant medicines become available for adults: a study on triptans in Finnish children 1994-2007.

  British journal of clinical pharmacology 20110601

• N-methyl-D-aspartate receptor-mediated modulations of the anti-allodynic effects of 5-HT1B/1D receptor stimulation in a rat model of trigeminal neuropathic pain.

  European journal of pain (London, England) 20110501

• Efficacy of frovatriptan in the acute treatment of menstrually related migraine: analysis of a double-blind, randomized, multicenter, Italian, comparative study versus zolmitriptan.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110501

• Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan.

  Cephalalgia : an international journal of headache 20110201

• Antimigraine efficacy of telcagepant based on patient's historical triptan response.

  Headache 20110101

• Autoradiographic Mapping of 5-HT(1B/1D) Binding Sites in the Rhesus Monkey Brain Using [carbonyl-C]zolmitriptan.

  International journal of molecular imaging 20110101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries.

  The Journal of pharmacology and experimental therapeutics 20100901

• Nitroglycerin provocation in normal subjects is not a useful human migraine model?

  Cephalalgia : an international journal of headache 20100801

• Zolmitriptan and human aggression: interaction with alcohol.

  Psychopharmacology 20100701

• Frovatriptan versus zolmitriptan for the acute treatment of migraine: a double-blind, randomized, multicenter, Italian study.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20100601

• Comparison of the vasoconstrictor effects of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) and zolmitriptan in human isolated coronary arteries.

  Journal of cardiovascular pharmacology 20100501

• Drug dependence associated with triptans and ergot derivatives: a case/non-case study.

  European journal of clinical pharmacology 20100401

• Micellar nanocarriers: potential nose-to-brain delivery of zolmitriptan as novel migraine therapy.

  Pharmaceutical research 20100401

• Anodic voltammetry of zolmitriptan at boron-doped diamond electrode and its analytical applications.

  Die Pharmazie 20100401

• Prinzmetal-variant angina in a patient using zolmitriptan and citalopram.

  The American journal of emergency medicine 20100201

• Triptans for acute cluster headache.

  The Cochrane database of systematic reviews 20100101

• A new stability indicating HPLC method for related substances in zolmitriptan.

  Indian journal of pharmaceutical sciences 20100101

• Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.

  Bioorganic & medicinal chemistry letters 20091201

• Preparation of zolmitriptan-chitosan microparticles by spray drying for nasal delivery.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091008

• Zolmitriptan nasal spray in the acute treatment of cluster headache: a meta-analysis of two studies.

  Headache 20091001

• Zolmitriptan compared to propranolol in the treatment of acute neuroleptic-induced akathisia: a comparative double-blind study.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090701

• Controlled non-invasive transdermal iontophoretic delivery of zolmitriptan hydrochloride in vitro and in vivo.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090601

• [Induction of rat hepatic cytochrome P-450 3A by zolmitriptan mediated with pregnane X receptor].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20090501

• Evidence base for the medical treatments used in cluster headache.

  Current pain and headache reports 20090401

• Migraine and telcagepant [corrected].

  Lancet (London, England) 20090321

• Molecule of the month. Telcagepant.

  Drug news & perspectives 20090301

• A study of the interaction between enantiomers of zolmitriptan and hydroxypropyl-beta-cyclodextrin by capillary electrophoresis.

  Analytical and bioanalytical chemistry 20090101

• Alcohol and cluster headaches.

  Headache 20090101

• [Cluster headache].

  Duodecim; laaketieteellinen aikakauskirja 20090101

• Triptans and troponin: a case report.

  Orphanet journal of rare diseases 20090101

• Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial.

  Lancet (London, England) 20081220

• CGRP-receptor antagonism in migraine treatment.

  Lancet (London, England) 20081220

• Male-specific induction of CYP3A2 in rats by zolmitriptan.

  The Journal of pharmacy and pharmacology 20081201

• Difference in triptan effect in patients with migraine and early allodynia.

  Cephalalgia : an international journal of headache 20081001

• In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions.

  Basic & clinical pharmacology & toxicology 20080801

• Tactile-induced ultrasonic vocalization in the rat: a novel assay to assess anti-migraine therapies in vivo.

  Cephalalgia : an international journal of headache 20080701

• Meta-analysis of the efficacy and safety of zolmitriptan in the acute treatment of migraine.

  Headache 20080201

• Fabrication of molecularly imprinted hybrid monoliths via a room temperature ionic liquid-mediated nonhydrolytic sol-gel route for chiral separation of zolmitriptan by capillary electrochromatography.

  Electrophoresis 20080201

• Acute treatment of paediatric migraine: a meta-analysis of efficacy.

  Journal of paediatrics and child health 20080101

• Oral zolmitriptan in the short-term prevention of menstrual migraine: a randomized, placebo-controlled study.

  CNS drugs 20080101

• Clinical pharmacology of the serotonin receptor agonist, zolmitriptan.

  Expert opinion on drug metabolism & toxicology 20071201

• Renal ischaemic injuries during the use of zolmitriptan for treatment of migraines in a transplanted patient under tacrolimus therapy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101

• [Muscle cramps and myalgia related to zolmitriptan].

  Revista de neurologia 20071101

• [Trigeminal autonomic cephalgias: diagnostic and therapeutic implications].

  MMW Fortschritte der Medizin 20070906

• Patient preference for triptan formulations: a prospective study with zolmitriptan.

  Headache 20070901

• Meta-analysis examining the efficacy and safety of almotriptan in the acute treatment of migraine.

  Headache 20070901

• Zolmitriptan nasal spray in the acute treatment of cluster headache: a double-blind study.

  Neurology 20070828

• Acute renal failure in a 17-year-old female with ALL receiving escalating intravenous methotrexate without leukovorin.

  Pediatric blood & cancer 20070801

• Efficacy of zolmitriptan nasal spray in adolescent migraine.

  Pediatrics 20070801

• The impact of migraine: a case study.

  The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20070801

• The 1:1 inclusion compounds zolmitriptan-benzene and zolmitriptan-phenol.

  Acta crystallographica. Section C, Crystal structure communications 20070701

• Characterization of the human basilar artery contractile response to 5-HT and triptans.

  Fundamental & clinical pharmacology 20070601

• Transport characteristics of zolmitriptan in a human intestinal epithelial cell line Caco-2.

  The Journal of pharmacy and pharmacology 20070501

• Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.

  Neurology 20070424

• [Intranasal zolmitriptan acts quickly].

  Medizinische Monatsschrift fur Pharmazeuten 20070301

• Almotriptan and zolmitriptan in the acute treatment of migraine.

  Acta neurologica Scandinavica 20070101

• Effectiveness and satisfaction with zolmitriptan 5 mg nasal spray for treatment of migraine in real-life practice: results of a postmarketing surveillance study.

  Clinical drug investigation 20070101

• Hemifacial spasm and cluster headache.

  Cephalalgia : an international journal of headache 20070101

• Extractive spectrophotometric methods for determination of zolmitriptan in tablets.

  Journal of AOAC International 20070101

• Improved migraine management in primary care: results of a patient treatment experience study using zolmitriptan orally disintegrating tablet.

  International journal of clinical practice 20061201

• Effectiveness of intranasal zolmitriptan in acute cluster headache: a randomized, placebo-controlled, double-blind crossover study.

  Archives of neurology 20061101

• Zolmitriptan uptake by human intestinal epithelial Caco-2 cells.

  Die Pharmazie 20061001

• Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.

  Neurology 20060808

• Daily morning hemifacial spasm in a patient with cluster headache.

  Cephalalgia : an international journal of headache 20060601

• Efficacy and tolerability of almotriptan versus zolmitriptan for the acute treatment of menstrual migraine.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060501

• [Symptomatic treatment of migraine with zolmitriptan: experience with 82 patients].

  Neurologia (Barcelona, Spain) 20060501

• [Experience with intranasal zolmitriptan in cluster headache].

  Neurologia (Barcelona, Spain) 20060401

• Determination of zolmitriptan in human plasma by liquid chromatography-tandem mass spectrometry method: application to a pharmacokinetic study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217

• Blood-brain barrier penetration of zolmitriptan--modelling of positron emission tomography data.

  Journal of pharmacokinetics and pharmacodynamics 20060201

• Zolmitriptan oral tablet in migraine treatment: high placebo responses in adolescents.

  Headache 20060101

• Zolmitriptan intranasal: a review of the pharmacokinetics and clinical efficacy.

  Headache 20060101

• [Medical treatment of migraine attacks in the child].

  Revue de l'infirmiere 20060101

• Antimigraine drug, zolmitriptan, inhibits high-voltage activated calcium currents in a population of acutely dissociated rat trigeminal sensory neurons.

  Molecular pain 20060101

• Renal infarction during the use of rizatriptan and zolmitriptan: two case reports.

  Clinical toxicology (Philadelphia, Pa.) 20060101

• Efficacy and tolerability of zolmitriptan oral tablet in the acute treatment of menstrual migraine.

  CNS drugs 20060101

• Molecular drug targets and structure based drug design: A holistic approach.

  Bioinformation 20060101

• Distribution of intranasal C-zolmitriptan assessed by positron emission tomography.

  Cephalalgia : an international journal of headache 20051201

• The study of enantioseparation of zolmitriptan on vancomycin-bonded chiral stationary phase.

  Journal of separation science 20051201

• Over-the-counter triptans--making the switch.

  The Lancet. Neurology 20051001

• A stability indicating LC method for zolmitriptan.

  Journal of pharmaceutical and biomedical analysis 20050915

• A validated chiral LC method for the enantiomeric separation of Zolmitriptan key intermediate, ZTR-5.

  Journal of pharmaceutical and biomedical analysis 20050915

• [Extrahepatic cholestasia during therapy with Zolmitriptan (AscoTop)].

  Zeitschrift fur Gastroenterologie 20050901

• Sumatriptan and zolmitriptan.

  Nursing times 20050901

• Multiple attack study on the available triptans in Italy versus placebo.

  European journal of neurology 20050701

• Intranasal zolmitriptan.

  Expert opinion on pharmacotherapy 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• The treatment of pediatric migraine.

  Pediatric annals 20050601

• Intranasal mucoadhesive microemulsions of zolmitriptan: preliminary studies on brain-targeting.

  Journal of drug targeting 20050601

• Triptans induce vasoconstriction of human arteries and veins from the thoracic wall.

  Journal of cardiovascular pharmacology 20050501

• Anti-migraine action of triptans is preceded by transient aggravation of headache caused by activation of meningeal nociceptors.

  Pain 20050501

• Myocardial infarction after taking zolmitriptan.

  The Yale journal of biology and medicine 20050501

• Determination of zolmitriptan enantiomers in rat liver microsomes by chiral high performance liquid chromatography with fl uorescence detection.

  Biomedical chromatography : BMC 20050401

• A validated chiral LC method for the determination of zolmitriptan and its potential impurities.

  Journal of pharmaceutical and biomedical analysis 20050309

• Pain-free rates with zolmitriptan 2.5 mg ODT in the acute treatment of migraine: results of a large double-blind placebo- controlled trial.

  Current medical research and opinion 20050301

• [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.

  Naunyn-Schmiedeberg's archives of pharmacology 20050301

• The 5-HT1D receptor agonist zolmitriptan for neuroleptic-induced akathisia: an open label preliminary study.

  International clinical psychopharmacology 20050101

• Correlation between lipophilicity and triptan outcomes.

  Headache 20050101

• Zolmitriptan 5 mg nasal spray: efficacy and onset of action in the acute treatment of migraine--results from phase 1 of the REALIZE Study.

  Headache 20050101

• Zolmitriptan nasal spray exhibits good long-term safety and tolerability in migraine: results of the INDEX trial.

  Headache 20050101

• Speed of onset, efficacy and tolerability of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled study.

  CNS drugs 20050101

• Distribution of zolmitriptan into the CNS in healthy volunteers: a positron emission tomography study.

  Drugs in R&D 20050101

• Part II: clinical efficacy and tolerability of zolmitriptan orally disintegrating tablet in the acute treatment of migraine.

  Current medical research and opinion 20050101

• Part III: the convenience of, and patient preference for, zolmitriptan orally disintegrating tablet.

  Current medical research and opinion 20050101

• Part IV: effects of zolmitriptan orally disintegrating tablet on migraine symptoms and ability to perform normal activities: a post-marketing surveillance study in Germany.

  Current medical research and opinion 20050101

• Myalgia and cramps associated with zolmitriptan.

  Clinical neuropharmacology 20050101

• Treatment satisfaction with zolmitriptan nasal spray for migraine in a real life setting: results from phase two of the REALIZE study.

  The journal of headache and pain 20050101

• Quantification of zolmitriptan in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

• Role of alcohol consumption in escalation to violence.

  Annals of the New York Academy of Sciences 20041201

• Benefits of treating highly disabled migraine patients with zolmitriptan while pain is mild.

  Cephalalgia : an international journal of headache 20041101

• Migraine treatment strategies: the global Migraine And Zolmitriptan Evaluation (MAZE) survey--phase IV.

  Current medical research and opinion 20041101

• Acute myocardial infarction following the use of antimigraine therapy.

  The Journal of invasive cardiology 20041001

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  No to shinkei = Brain and nerve 20040901

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  No to shinkei = Brain and nerve 20040901

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  No to shinkei = Brain and nerve 20040901

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  Cephalalgia : an international journal of headache 20040801

• The therapeutic profile of zolmitriptan in clinical practice.

  International journal of clinical practice 20040801

• Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.

  Naunyn-Schmiedeberg's archives of pharmacology 20040701

• Impact of migraine on patients and their families: the Migraine And Zolmitriptan Evaluation (MAZE) survey--Phase III.

  Current medical research and opinion 20040701

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  Clinical evidence 20040601

• High-performance liquid chromatographic analysis of zolmitriptan in human plasma using fluorescence detection.

  Journal of pharmaceutical and biomedical analysis 20040528

• Double-blind clinical trials of oral triptans vs other classes of acute migraine medication - a review.

  Cephalalgia : an international journal of headache 20040501

• Effects of chronic sumatriptan and zolmitriptan treatment on 5-HT receptor expression and function in rats.

  Cephalalgia : an international journal of headache 20040501

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  Neurologia (Barcelona, Spain) 20040501

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  Headache 20040301

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  International journal of clinical practice 20040301

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  Headache 20040201

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  Pharmacoepidemiology and drug safety 20040201

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  Health news (Waltham, Mass.) 20040201

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  The Medical letter on drugs and therapeutics 20040119

• Effects of acute or chronic administration of anti-migraine drugs sumatriptan and zolmitriptan on serotonin synthesis in the rat brain.

  Cephalalgia : an international journal of headache 20040101

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  Annals of neurology 20040101

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  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040101

• Fixed drug eruption of the penis due to zolmitriptan.

  Dermatology (Basel, Switzerland) 20040101

• Determining triptan preference for the individual patient.

  Headache 20040101

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  CNS drugs 20040101

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  CNS drugs 20040101

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  Expert review of neurotherapeutics 20040101

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  Chemico-biological interactions 20031215

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  Gastroenterologia y hepatologia 20031201

• Comparative efficacy of eletriptan and zolmitriptan in the acute treatment of migraine.

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• Migraine headache.

  Clinical evidence 20031201

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  Neurology 20031028

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  Neurology 20031028

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  Cephalalgia : an international journal of headache 20031001

• Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet.

  International journal of clinical practice 20030901

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  Drug metabolism and disposition: the biological fate of chemicals 20030701

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  Current opinion in neurology 20030601

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  MMW Fortschritte der Medizin 20030526

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  MMW Fortschritte der Medizin 20030526

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  Current pain and headache reports 20030401

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  Neurology 20030311

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  Praxis 20030226

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  Journal of clinical pharmacy and therapeutics 20030201

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  Schmerz (Berlin, Germany) 20030101

• Speed of onset and efficacy of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled, dose-ranging study versus zolmitriptan tablet.

  CNS drugs 20030101

• Migraine prevalence and treatment patterns: the global Migraine and Zolmitriptan Evaluation survey.

  Headache 20030101

• Transcranial Doppler in migraine attacks before and after treatment with oral zolmitriptan or sumatriptan.

  Headache 20030101

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  Drugs 20030101

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  CNS drugs 20030101

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  Drugs 20030101

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  Headache 20030101

• The antimigraine 5-HT 1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain.

  British journal of pharmacology 20021201

• Ergot and triptan overuse in Austria--an evaluation of clinical data and cost.

  Cephalalgia : an international journal of headache 20021201

• Preliminary studies of the pharmacokinetics and tolerability of zolmitriptan nasal spray in healthy volunteers.

  Journal of clinical pharmacology 20021101

• Pharmacokinetics, dose proportionality, and tolerability of single and repeat doses of a nasal spray formulation of zolmitriptan in healthy volunteers.

  Journal of clinical pharmacology 20021101

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  Psychopharmacology 20021001

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  Neurology 20020827

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  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020801

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  Expert opinion on pharmacotherapy 20020701

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  Archives of neurology 20020701

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  European journal of clinical pharmacology 20020701

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• Re: Zakrzewska JM. Cluster headache: review of the literature. Br J Oral Maxillofac Surg 2001; 39: 103-113.

  The British journal of oral & maxillofacial surgery 20020201

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  Headache 20020201

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  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020125

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  Ideggyogyaszati szemle 20020120

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  European neurology 20020101

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  Medicina (Kaunas, Lithuania) 20020101

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  Functional neurology 20020101

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  Neurology 20011113

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  Neurology 20011023

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  Cephalalgia : an international journal of headache 20011001

• Have the triptans fulfilled their promise?

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20010901

• Triptans are all different.

  Archives of neurology 20010901

• What matters is not the differences between triptans, but the differences between patients.

  Archives of neurology 20010901

• Effect of rizatriptan and other triptans on the nausea symptom of migraine: a post hoc analysis.

  Headache 20010901

• Zolmitriptan--a 5-HT1B/D agonist, alcohol, and aggression in mice.

  Psychopharmacology 20010901

• Serotonergic effects and extracellular brain levels of eletriptan, zolmitriptan and sumatriptan in rat brain.

  European journal of pharmacology 20010817

• Establishing a standard of speed for assessing the efficacy of the serotonin(1B/1D) agonists (triptans).

  Archives of neurology 20010701

• An open preference study with sumatriptan 50 mg and zolmitriptan 2.5 mg in 100 migraine patients.

  Cephalalgia : an international journal of headache 20010701

• Recent development in paediatric headache.

  Current opinion in neurology 20010601

• Zolmitriptan versus sumatriptan for the acute oral treatment of migraine: a randomized, double-blind, international study.

  European journal of neurology 20010501

• Decreased sensitivity of 5-HT(1D) receptors in melancholic depression.

  The British journal of psychiatry : the journal of mental science 20010501

• [Current topics: expectation for new triptans].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20010410

• Discovery of 4-[3-(trans-3-dimethylaminocyclobutyl)-1H-indol-5-ylmethyl]-(4S)-oxazolidin-2-one (4991W93), a 5HT(1B/1D) receptor partial agonist and a potent inhibitor of electrically induced plasma extravasation.

  Journal of medicinal chemistry 20010301

• Zolmitriptan versus sumatriptan comparison trial.

  Headache 20010301

• Acute treatment of migraine and the role of triptans.

  Current neurology and neuroscience reports 20010301

• What is the optimal strategy for managing acute migraine headaches?

  The Journal of family practice 20010201

• New abortive agents for the treatment of migraine.

  Advances in internal medicine 20010101

• NMR studies on three optical active drug molecules.

  Acta poloniae pharmaceutica 20010101

• The cost effectiveness of stratified care in the management of migraine.

  PharmacoEconomics 20010101

• Triptans in the treatment of basilar migraine and migraine with prolonged aura.

  Headache 20010101

• Zolmitriptan: differences from sumatriptan.

  Current medical research and opinion 20010101

• Comparative aspects of triptans in treating migraine.

  Clinical cornerstone 20010101

• Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?

  Cephalalgia : an international journal of headache 20001001

• Profiles of 5-HT 1B/1D agonists in acute migraine with special reference to second generation agents.

  Acta neurologica Belgica 19990601

• Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors.

  European journal of pharmacology 19990305

• [Mechanism of action of zolmitriptan].

  Neurologia (Barcelona, Spain) 19981001

• Zolmitriptan (311C90) does not interact with fluoxetine in healthy volunteers.

  International journal of clinical pharmacology and therapeutics 19980601

• Pharmacological analysis of the haemodynamic effects of 5-HT1B/D receptor agonists in the normotensive rat.

  British journal of pharmacology 19980101

• Pre-clinical pharmacology of zolmitriptan (Zomig; formerly 311C90), a centrally and peripherally acting 5HT1B/1D agonist for migraine.

  Cephalalgia : an international journal of headache 19971001