14003-96-4 | 7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$18.00	$13.00
5mg	98%	in stock	$40.00	$28.00
10mg	98%	in stock	$60.00	$42.00
25mg	98%	in stock	$90.00	$63.00
50mg	98%	in stock	$136.00	$95.00

Description

• Catalog Number: AA61959
• Chemical Name: 7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde
• CAS Number: 14003-96-4
• Molecular Formula: C11H8O4
• Molecular Weight: 204.1788
• MDL Number: MFCD12027255
• SMILES: O=Cc1c(O)ccc2c1oc(=O)cc2C

Computed Properties

• Complexity: 321
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.5

Literature

• Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity.

  Journal of medicinal chemistry 20140522

• Synthesis, spectroscopic characterization and biological evaluation studies of Schiff's base derived from naphthofuran-2-carbohydrazide with 8-formyl-7-hydroxy-4-methyl coumarin and its metal complexes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

• 8-Formyl-4-methyl-2-oxo-2H-chromen-7-yl 4-methyl-benzenesulfonate.

  Acta crystallographica. Section E, Structure reports online 20110601

• Synthesis, physico-chemical investigations of Co(II), Ni(II) and Cu(II) complexes and their in vitro microbial, cytotoxic, DNA cleavage studies.

  Journal of enzyme inhibition and medicinal chemistry 20100601

• DNA cleavage and in vitro antimicrobial studies of Co(II), Ni(II), and Cu(II) complexes with ONNO donor Schiff bases: synthesis, spectral characterization, and electrochemical studies.

  Journal of enzyme inhibition and medicinal chemistry 20100201

• Synthesis, characterization, DNA cleavage and in vitro antimicrobial studies of La(III), Th(IV) and VO(IV) complexes with Schiff bases of coumarin derivatives.

  European journal of medicinal chemistry 20090701

• Synthesis, spectral characterization, in vitro microbial and cytotoxic studies of lanthanum(III) and thorium(IV) complexes with 1,2,4-triazole Schiff bases.

  Journal of enzyme inhibition and medicinal chemistry 20090601

• Synthesis, spectral characterization and in vitro biological studies of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases.

  Journal of enzyme inhibition and medicinal chemistry 20090401

• Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases.

  European journal of medicinal chemistry 20081201

• Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.

  Journal of medicinal chemistry 20080227