1403254-99-8 | Epz-6438

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$16.00	$11.00
5mg	97%	in stock	$20.00	$14.00
10mg	97%	in stock	$36.00	$25.00
25mg	97%	in stock	$44.00	$31.00
50mg	97%	in stock	$52.00	$36.00
100mg	97%	in stock	$76.00	$53.00
250mg	97%	in stock	$123.00	$86.00
1g	97%	in stock	$326.00	$228.00
5g	97%	in stock	$1,131.00	$792.00

Description

• Catalog Number: AE35667
• Chemical Name: Epz-6438
• CAS Number: 1403254-99-8
• Molecular Formula: C34H44N4O4
• Molecular Weight: 572.7376
• MDL Number: MFCD24849415
• SMILES: CCN(c1cc(cc(c1C)C(=O)NCc1c(C)cc([nH]c1=O)C)c1ccc(cc1)CN1CCOCC1)C1CCOCC1

Computed Properties

• Complexity: 992
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 42
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 9
• XLogP3: 4.2

Upstream Synthesis Route

The compound N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-carboxamide is commonly utilized in chemical synthesis as a versatile building block. Its unique structure contains multiple functional groups that can participate in a variety of synthetic reactions, making it valuable for constructing complex molecules such as pharmaceutical intermediates or fine chemicals. The presence of the amide, amino, methyl, and morpholinyl groups in the molecule enables it to engage in diverse chemical transformations, facilitating the creation of structurally intricate and biologically active compounds. In organic synthesis, this compound serves as a key component for the development of novel chemical entities with potential applications in medicinal chemistry, materials science, and other fields requiring the creation of specialized molecules.

Literature

• Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2.

  Proceedings of the National Academy of Sciences of the United States of America 20130507