1408168-69-3 | Potassium (2-methoxyethyl)trifluoroborate

Packsize	Purity	Availability	Price	Discounted Price
100mg	96%	in stock	$203.00	$142.00
250mg	96%	in stock	$323.00	$226.00
1g	96%	in stock	$907.00	$635.00
5g	96%	in stock	$2,702.00	$1,892.00
10g	96%	in stock	$4,497.00	$3,148.00

Description

• Catalog Number: AE39902
• Chemical Name: Potassium (2-methoxyethyl)trifluoroborate
• CAS Number: 1408168-69-3
• Molecular Formula: C3H7BF3KO
• Molecular Weight: 165.9916
• MDL Number: MFCD18861717
• SMILES: COCC[B-](F)(F)F.[K+]

Upstream Synthesis Route

To synthesize Potassium (2-methoxyethyl)trifluoroborate (KF(MeOCH2CH2)BF3), one might commence with 2-chloroethanol as the starting material. Firstly, perform an O-alkylation using a methylating agent such as dimethyl sulfate or methyl iodide to obtain 2-methoxyethanol. This alkoxyethanol is then converted to its corresponding tosylate or mesylate ester by treatment with p-toluenesulfonyl chloride or methanesulfonyl chloride respectively in the presence of a base, typically triethylamine (TEA).

Next, conduct a nucleophilic substitution of the tosylate/mesylate with a fluoride source, for instance, tetrabutylammonium fluoride (TBAF) to yield 2-methoxyethyl fluoride. This fluoride is then subjected to a boronation reaction using a boron trifluoride (BF3) donor, such as triethylborane, creating the corresponding 2-methoxyethyltrifluoroborate ester.

Finally, a salt metathesis is carried out by treating the ester with potassium carbonate (K2CO3) in a suitable solvent such as aqueous solution or acetonitrile, affording the desired Potassium (2-methoxyethyl)trifluoroborate product upon purification, commonly executed through crystallization or precipitation, followed by filtration and drying.