14197-60-5 | Ginsenoside rg3

Packsize	Purity	Availability	Price	Discounted Price
5mg	95%	in stock	$36.00	$25.00
25mg	95%	in stock	$96.00	$67.00
100mg	95%	in stock	$283.00	$198.00

Description

• Catalog Number: AD22245
• Chemical Name: Ginsenoside rg3
• CAS Number: 14197-60-5
• Molecular Formula: C42H72O13
• Molecular Weight: 785.0133
• MDL Number: MFCD06410950
• SMILES: OC[C@H]1O[C@@H](O[C@H]2CC[C@]3([C@H](C2(C)C)CC[C@@]2([C@@H]3C[C@@H](O)[C@H]3[C@@]2(C)CC[C@@H]3[C@](CCC=C(C)C)(O)C)C)C)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O

Computed Properties

• Complexity: 1370
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 20
• Heavy Atom Count: 55
• Hydrogen Bond Acceptor Count: 13
• Hydrogen Bond Donor Count: 9
• Rotatable Bond Count: 10
• XLogP3: 4

Literature

• Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype.

  Chemico-biological interactions 20180301

• Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway.

  Chemico-biological interactions 20160825

• Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

  Toxicology in vitro : an international journal published in association with BIBRA 20160301

• Novel roles of ginsenoside Rg3 in apoptosis through downregulation of epidermal growth factor receptor.

  Chemico-biological interactions 20150525

• Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance.

  Toxicology 20140801

• YY162 prevents ADHD-like behavioral side effects and cytotoxicity induced by Aroclor1254 via interactive signaling between antioxidant potential, BDNF/TrkB, DAT and NET.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140301

• Ginsenoside Re and Rd enhance the expression of cholinergic markers and neuronal differentiation in Neuro-2a cells.

  Biological & pharmaceutical bulletin 20140101

• Chronic treatment with ginsenoside Rg3 induces Akt-dependent senescence in human glioma cells.

  International journal of oncology 20121101

• Neuroprotective effect of 20(R)-ginsenoside Rg(3) against transient focal cerebral ischemia in rats.

  Neuroscience letters 20120927

• Ginsenoside Rg3 inhibits endothelial progenitor cell differentiation through attenuation of VEGF-dependent Akt/eNOS signaling.

  Phytotherapy research : PTR 20120901

• Conversion of protopanaxadiol type saponins to ginsenoside Rg3 by lemon.

  Natural product communications 20120901

• Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling.

  Journal of natural medicines 20120701

• Ginsenoside Rg3 enhances the chemosensitivity of tumors to cisplatin by reducing the basal level of nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1/NAD(P)H quinone oxidoreductase-1 and prevents normal tissue damage by scavenging cisplatin-induced intracellular reactive oxygen species.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120701

• Stereospecificity of ginsenoside Rg3 in promotion of the immune response to ovalbumin in mice.

  International immunology 20120701

• Stereospecific antioxidant effects of ginsenoside Rg3 on oxidative stress induced by cyclophosphamide in mice.

  Fitoterapia 20120601

• Ginsenoside Rg3 attenuates cell migration via inhibition of aquaporin 1 expression in PC-3M prostate cancer cells.

  European journal of pharmacology 20120515

• Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells.

  Cancer biology & therapy 20120501

• Stereoisomers ginsenosides-20(S)-Rg₃ and -20(R)-Rg₃ differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma.

  Biochemical pharmacology 20120401

• Enzymatic biotransformation of ginsenoside Rb1 to 20(S)-Rg3 by recombinant β-glucosidase from Microbacterium esteraromaticum.

  Applied microbiology and biotechnology 20120401

• Microbial transformation of ginsenoside Rg3 to ginsenoside Rh2 by Esteya vermicola CNU 120806.

  World journal of microbiology & biotechnology 20120401

• Effects of ginseng rhizome and ginsenoside Ro on testosterone 5α-reductase and hair re-growth in testosterone-treated mice.

  Phytotherapy research : PTR 20120101

• Cytoprotective effect of 20S-Rg3 on benzo[a]pyrene-induced DNA damage.

  Drug metabolism and disposition: the biological fate of chemicals 20120101

• Ginsenoside Rg3 reduces lipid accumulation with AMP-Activated Protein Kinase (AMPK) activation in HepG2 cells.

  International journal of molecular sciences 20120101

• Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells.

  Basic & clinical pharmacology & toxicology 20111001

• Ginsenoside Rg3 inhibits CXCR4 expression and related migrations in a breast cancer cell line.

  International journal of clinical oncology 20111001

• Ginsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway.

  World journal of gastroenterology 20110821

• Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: a 26-week intramuscular repeated administration study in Beagle dogs.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801

• Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction.

  European journal of pharmacology 20110801

• Effect of ginsenosides Rg3 and Re on glucose transport in mature 3T3-L1 adipocytes.

  Phytotherapy research : PTR 20110501

• Immunopotentiation and antitumor effects of a ginsenoside Rg₃-fortified red ginseng preparation in mice bearing H460 lung cancer cells.

  Environmental toxicology and pharmacology 20110501

• [Effect of ginsenoside Rg3 on hepatic fibrosis in murine schistosomiasis japonica].

  Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20110430

• Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds.

  Journal of natural products 20110425

• Antidepressant-like effect of altered Korean red ginseng in mice.

  Behavioral medicine (Washington, D.C.) 20110401

• Ginsenoside Rg3 enhances large conductance Ca2+-activated potassium channel currents: a role of Tyr360 residue.

  Molecules and cells 20110227

• Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53.

  Cancer letters 20110227

• Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling.

  International journal of oncology 20110201

• Effects of ginsenoside on large-conductance K(Ca) channels in human corporal smooth muscle cells.

  International journal of impotence research 20110101

• Vascular smooth muscle dysfunction and remodeling induced by ginsenoside Rg3, a bioactive component of ginseng.

  Toxicological sciences : an official journal of the Society of Toxicology 20101001

• [Inhibitory effect of ginsenoside Rg3 on the tube-like structure formation in human nasopharyngeal carcinoma HNE-1 cell line in vitro].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001

• Enzymatic preparation of 20(S, R)-protopanaxadiol by transformation of 20(S, R)-Rg3 from black ginseng.

  Phytochemistry 20100901

• Ginsenoside Rg3 inhibits tumor necrosis factor-alpha-induced expression of cell adhesion molecules in human endothelial cells.

  Die Pharmazie 20100901

• Determination of ginsenoside Rg3 in human plasma and urine by high performance liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100815

• Ginsenoside rb1 and rg3 attenuate glucocorticoid-induced neurotoxicity.

  Cellular and molecular neurobiology 20100801

• Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit.

  European journal of pharmacology 20100710

• Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides.

  Bioorganic & medicinal chemistry letters 20100501

• Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB.

  European journal of pharmacology 20100410

• Improving enzymatic production of ginsenoside Rh2 from Rg3 by using nonionic surfactant.

  Applied biochemistry and biotechnology 20100201

• Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

• The ginsenoside Rg3 has a stimulatory effect on insulin signaling in L6 myotubes.

  Biochemical and biophysical research communications 20091106

• [Efficacy of Shenyi Capsule combined with gemcitabine plus cisplatin in treatment of advanced esophageal cancer: a randomized controlled trial].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20091101

• [The effects of ginsenosides Rg3 on the expressions of VEGF and KDR in human lung squamous cancer cells].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091101

• Optimization of the enzymatic production of 20(S)-ginsenoside Rg(3) from white ginseng extract using response surface methodology.

  New biotechnology 20091031

• [Ginsenoside Rg3 induces apoptosis of human lung squamous cell carcinoma SK-MES-1 cell line].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901

• Mutations Leu427, Asn428, and Leu431 residues within transmembrane domain-I-segment 6 attenuate ginsenoside-mediated L-type Ca(2+) channel current inhibitions.

  Biological & pharmaceutical bulletin 20090701

• Anxiolytic-like effects of ginsenosides Rg3 and Rh2 from red ginseng in the elevated plus-maze model.

  Planta medica 20090601

• A role for Leu247 residue within transmembrane domain 2 in ginsenoside-mediated alpha7 nicotinic acetylcholine receptor regulation.

  Molecules and cells 20090531

• Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel.

  Archives of pharmacal research 20090501

• [Effect of ginsenoside Rg3 on Pim-3 and Bad proteins in human pancreatic cancer cell line PANC-1].

  Ai zheng = Aizheng = Chinese journal of cancer 20090501

• Proteomic analysis of the anti-cancer effect of 20S-ginsenoside Rg3 in human colon cancer cell lines.

  Bioscience, biotechnology, and biochemistry 20090423

• 20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain.

  Phytotherapy research : PTR 20090401

• Generation and characterization of monoclonal antibody to ginsenoside rg3.

  Biological & pharmaceutical bulletin 20090401

• The effects of ginsenoside Rg(3) on human Kv1.4 channel currents without the N-terminal rapid inactivation domain.

  Biological & pharmaceutical bulletin 20090401

• Ginsenoside Rg3 promotes beta-amyloid peptide degradation by enhancing gene expression of neprilysin.

  The Journal of pharmacy and pharmacology 20090301

• Antiobesity effect of ginsenoside Rg3 involves the AMPK and PPAR-gamma signal pathways.

  Phytotherapy research : PTR 20090201

• [Effect of gensenoside Rg3 on apoptosis of Hep-2 and expression of HIF-1alha in human laryngeal cancer cell line under anoxic conditions].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090101

• Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice.

  BMC cancer 20090101

• The anti-fatigue effect of 20(R)-ginsenoside Rg3 in mice by intranasally administration.

  Biological & pharmaceutical bulletin 20081101

• Research on the antitumor effect of ginsenoside Rg3 in B16 melanoma cells.

  Melanoma research 20081001

• Antiangiogenic effect of capecitabine combined with ginsenoside Rg3 on breast cancer in mice.

  Cancer biotherapy & radiopharmaceuticals 20081001

• Therapeutic potential of 20(S)-ginsenoside Rg(3) against streptozotocin-induced diabetic renal damage in rats.

  European journal of pharmacology 20080904

• [Fungal biotransformation of ginsenoside Rg3].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20080901

• Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis.

  Chinese medical journal 20080805

• Metabonomics study on the effects of the ginsenoside Rg3 in a beta-cyclodextrin-based formulation on tumor-bearing rats by a fully automatic hydrophilic interaction/reversed-phase column-switching HPLC-ESI-MS approach.

  Analytical chemistry 20080615

• Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells.

  International journal of oncology 20080501

• Involvement of batrachotoxin binding sites in ginsenoside-mediated voltage-gated Na+ channel regulation.

  Brain research 20080408

• 20(S)-ginsenoside Rg3 enhances glucose-stimulated insulin secretion and activates AMPK.

  Biological & pharmaceutical bulletin 20080401

• Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue.

  Molecular pharmacology 20080301

• Effect and mechanism of ginsenoside Rg3 on postoperative life span of patients with non-small cell lung cancer.

  Chinese journal of integrative medicine 20080301

• Modifications of aliphatic side chain of 20(S)-ginsenoside RG3 cause an enhancement or loss of brain Na+ channel current inhibitions.

  Biological & pharmaceutical bulletin 20080301

• [Raman spectroscopy study on the structure of ginsenoside Rg3].

  Guang pu xue yu guang pu fen xi = Guang pu 20080301

• 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol, a novel natural product for prostate cancer therapy: activity in vitro and in vivo and mechanisms of action.

  British journal of cancer 20080226

• Protective effects of ginsenoside Rg(3) against cyclophosphamide-induced DNA damage and cell apoptosis in mice.

  Archives of toxicology 20080201

• Selective toxicity of ginsenoside Rg3 on multidrug resistant cells by membrane fluidity modulation.

  Archives of pharmacal research 20080201

• Neuroprotective effects of ginseng saponins against L-type Ca2+ channel-mediated cell death in rat cortical neurons.

  Biochemical and biophysical research communications 20080118

• Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514.

  Phytochemistry 20080101

• [Correlation of insulin-like growth factor-1 (IGF-1) to angiogenesis of breast cancer in IGF-1-deficient mice].

  Ai zheng = Aizheng = Chinese journal of cancer 20071101

• Preventive effect of 20(S)-ginsenoside Rg3 against lipopolysaccharide-induced hepatic and renal injury in rats.

  Free radical research 20071001

• Marked production of ginsenosides Rd, F2, Rg3, and compound K by enzymatic method.

  Chemical & pharmaceutical bulletin 20071001

• Mutations of arginine 222 in pre-transmembrane domain I of mouse 5-HT(3A) receptor abolish 20(R)- but not 20(S)-ginsenoside Rg(3) inhibition of 5-HT-mediated ion currents.

  Biological & pharmaceutical bulletin 20070901

• Panaxadiol glycosides that induce neuronal differentiation in neurosphere stem cells.

  Journal of natural products 20070801

• [Inducement effect of ginsenoside Rg3 on apoptosis of human bladder transitional cell carcinoma cell line EJ].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

• Bifidus fermentation increases hypolipidemic and hypoglycemic effects of red ginseng.

  Journal of microbiology and biotechnology 20070701

• Red American ginseng: ginsenoside constituents and antiproliferative activities of heat-processed Panax quinquefolius roots.

  Planta medica 20070601

• Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer.

  Chinese medical journal 20070405

• Neuroprotective effects of ginsenoside Rg3 against homocysteine-induced excitotoxicity in rat hippocampus.

  Brain research 20070309

• Identification of ginsenoside interaction sites in 5-HT3A receptors.

  Neuropharmacology 20070301

• [Effect of adjuvant chemotherapy of ginsenoside Rg3 combined with mitomycin C and tegafur in advanced gastric cancer].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20070101

• Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models.

  Biological & pharmaceutical bulletin 20060901

• The angiosuppressive effects of 20(R)- ginsenoside Rg3.

  Biochemical pharmacology 20060814

• [Determination of ginsenoside Rd and its metabolites in rat urine by LC-MS].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060801

• The antistress effect of ginseng total saponin and ginsenoside Rg3 and Rb1 evaluated by brain polyamine level under immobilization stress.

  Pharmacological research 20060701

• Reductions in levels of the Alzheimer's amyloid beta peptide after oral administration of ginsenosides.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060601

• Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/interferon-gamma-stimulated BV-2 microglial cells.

  Planta medica 20060601

• 20(S)-ginsenoside Rh2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons.

  European journal of pharmacology 20060424

• Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma.

  Biochemical and biophysical research communications 20060414

• Stereospecific effects of ginsenoside Rg3 epimers on swine coronary artery contractions.

  Biological & pharmaceutical bulletin 20060201

• [The effects of 20(R)-Rg3 on lung carcinoma A549 cell line and endogenous VEGF secreted by tumor cells].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060101

• [Metabolite fingerprint and biomarkers identification of rat urine after dosed with ginsenoside Rg3 based on ultra high performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS)].

  Se pu = Chinese journal of chromatography 20060101

• [Effects of ginsenoside Rg3 on the micro-lymphatic metastasis of colorectal neoplasms].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20051201

• Characteristics of ginsenoside Rg3-mediated brain Na+ current inhibition.

  Molecular pharmacology 20051001

• Hepatoprotective effect of 20(S)-ginsenosides Rg3 and its metabolite 20(S)-ginsenoside Rh2 on tert-butyl hydroperoxide-induced liver injury.

  Biological & pharmaceutical bulletin 20051001

• Potential effects of microglial activation induced by ginsenoside Rg3 in rat primary culture: enhancement of type A Macrophage Scavenger Receptor expression.

  Archives of pharmacal research 20051001

• Evidence that the tertiary structure of 20(S)-ginsenoside Rg(3) with tight hydrophobic packing near the chiral center is important for Na(+) channel regulation.

  Biochemical and biophysical research communications 20050812

• [Experimental study on anti-angiogenesis in mice with Lewis lung carcinoma by low-dose of cyclophosphamide combined with ginsenoside Rg3].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050801

• Relaxation of canine corporal smooth muscle relaxation by ginsenoside saponin Rg3 is independent from eNOS activation.

  Life sciences 20050520

• High performance liquid chromatographic-mass spectrometric determination of ginsenoside Rg3 and its metabolites in rat plasma using solid-phase extraction for pharmacokinetic studies.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050425

• [Effect of ginsenoside on the cellular proliferation, apoptosis and cell cycles in LC A549 and HUVEC 304 cell lines].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050401

• [The inhibition of 20(R)-ginsenoside Rg3 on the expressions of angiogenesis factors proteins in human lung adenocarcinoma cell line A549 and HUVEC304 cell].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

• [Anticarcinogenic effect of 20(R)-ginsenoside Rg3 on induced hepatocellular carcinoma in rats].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050301

• Memory enhancing and neuroprotective effects of selected ginsenosides.

  Archives of pharmacal research 20050301

• [Distribution and pharmacokinetics of 20S-ginsenoside Rg3 eyeointment in rabbit eye].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050301

• A role for the carbohydrate portion of ginsenoside Rg3 in Na+ channel inhibition.

  Molecules and cells 20050227

• In vivo rat metabolism and pharmacokinetic studies of ginsenoside Rg3.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

• Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats.

  Neuroscience letters 20050210

• Liquid chromatography/tandem mass spectrometry for pharmacokinetic studies of 20(R)-ginsenoside Rg3 in dog.

  Rapid communications in mass spectrometry : RCM 20050101

• [Experimental study on effect of chemotherapy combined ginsengnoside Rg3 in treating pulmonary carcinoma].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050101

• Evaluation of chemopreventive action and antimutagenic effect of the standardized Panax ginseng extract, EFLA400, in Swiss albino mice.

  Phytotherapy research : PTR 20050101

• Stereospecificity of ginsenoside Rg3 action on ion channels.

  Molecules and cells 20041231

• Changes of [3H]MK-801, [3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of transformed ginsenosides.

  Neurochemical research 20041201

• [Inhibitory effect of ginsenoside-Rg3 on lung metastasis of mouse melanoma transfected with ribonuclease inhibitor].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20041201

• Ginsenoside Rg3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons.

  Biochemical and biophysical research communications 20041015

• Hematopoietic effect of ginsenoside Rg3 in ICR mouse primary cultures and its application to a biological response modifier.

  Fitoterapia 20040601

• Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells.

  Archives of pharmacal research 20040401

• [Progress of the study on effective integredients from Chinese herbal medicine in anti-tumor metastasis].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040201

• Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase.

  British journal of pharmacology 20031001

• [Effect of ginsenoside Rg3 on the progression of orthotopically xenotransplanted human breast cancer in nude mice and its mechanism].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20030701

• [Advances in the study of tumor angiogenesis and anti-angiogenic Chinese herbal drugs].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030501

• Reversal of P-glycoprotein-mediated multidrug resistance by ginsenoside Rg(3).

  Biochemical pharmacology 20030101

• Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion.

  Mutation research 20030101

• [Effect of angiogenesis inhibitor Rg3 on the growth and metastasis of gastric cancer in SCID mice].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20020801

• [Antiangiogenesis of ginsenoside Rg3 in severe combined immunodeficient mice with human ovarian carcinoma].

  Zhonghua fu chan ke za zhi 20020401

• Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neurons.

  European journal of pharmacology 20020202

• Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities.

  Biological & pharmaceutical bulletin 20020101

• Characterization of ginseng saponin ginsenoside-Rg(3) inhibition of catecholamine secretion in bovine adrenal chromaffin cells.

  Biochemical pharmacology 20011001

• [Pharmacokinetic studies of 20(R)-ginsenoside RG3 in human volunteers].

  Yao xue xue bao = Acta pharmaceutica Sinica 20010301