1429-50-1 | Ethylenediaminetetra(methylenephosphonic acid)

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$17.00	$12.00
25g	95%	in stock	$24.00	$17.00
100g	95%	in stock	$62.00	$44.00
500g	96%	in stock	$251.00	$176.00

Description

• Catalog Number: AB74138
• Chemical Name: Ethylenediaminetetra(methylenephosphonic acid)
• CAS Number: 1429-50-1
• Molecular Formula: C6H20N2O12P4
• Molecular Weight: 436.1242
• MDL Number: MFCD00058893
• SMILES: OP(=O)(CN(CP(=O)(O)O)CCN(CP(=O)(O)O)CP(=O)(O)O)O

Computed Properties

• Complexity: 486
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 14
• Hydrogen Bond Donor Count: 8
• Rotatable Bond Count: 11
• XLogP3: -11.2

Literature

• Is ¹⁵³Samarium-ethylene-diamine-tetramethyl-phosphonate (EDTMP) bone uptake influenced by bisphosphonates in patients with castration-resistant prostate cancer?

  World journal of urology 20120401

• (153)Sm-EDTMP appears to accumulate only trivially within peritoneal ascites.

  Journal of nuclear medicine technology 20120301

• Lanthanides caged by the organic chelates; structural properties.

  Journal of physics. Condensed matter : an Institute of Physics journal 20110413

• Ethylene diamine tetramethylene phosphonic acid labeled with various β(-)-emitting radiometals: labeling optimization and animal biodistribution.

  Cancer biotherapy & radiopharmaceuticals 20110401

• Strategy for bone metastases treatment in patients with impending cord compression or vertebral fractures: a pilot study.

  World journal of nuclear medicine 20110101

• Multispecies animal investigation on biodistribution, pharmacokinetics and toxicity of 177Lu-EDTMP, a potential bone pain palliation agent.

  Nuclear medicine and biology 20100201

• Production, quality control and pharmacokinetic studies of Ho-EDTMP for therapeutic applications.

  Scientia pharmaceutica 20100101

• Studies on the development of 99mTc-labeled biphosphonate alginate beads.

  Hellenic journal of nuclear medicine 20100101

• Background, reasons and benefits using the vienna protocol for the treatment of painful bone recurrences with 153Samarium-EDTMP.

  Anticancer research 20090801

• [Bone-targeted ultradeformable nanoliposomes].

  Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20090418

• Controlled size and morphology of EDTMP-doped hydroxyapatite nanoparticles as model for 153Samarium-EDTMP doping.

  Journal of materials science. Materials in medicine 20080901

• 177Lu-EDTMP: a viable bone pain palliative in skeletal metastasis.

  Cancer biotherapy & radiopharmaceuticals 20080401

• Preparation and pre-vivo evaluation of no-carrier-added, carrier-added and cross-complexed [(68)Ga]-EDTMP formulations.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080201

• Pre vivo, ex vivo and in vivo evaluations of [68Ga]-EDTMP.

  Nuclear medicine and biology 20070501

• From structural properties of the EuIII complex with ethylenediaminetetra(methylenephosphonic acid) (H8EDTMP) towards biomedical applications.

  Dalton transactions (Cambridge, England : 2003) 20061021

• Clinical role of Sm-153 EDTMP in the treatment of painful bone metastatic disease.

  Clinical nuclear medicine 20061001

• Competitive adsorption of phosphate and phosphonates onto goethite.

  Water research 20060601

• Samarium-153 ethylenediamine tetramethylene phosphonate therapy for bone pain palliation in skeletal metastases.

  Indian journal of cancer 20060101

• Binding studies of [18F]-fluoride and polyphosphonates radiolabelled with [99mTc], [111In], [153Sm] and [188Re] on bone compartments: verification of the pre vivo model?

  Bone 20050901

• Modeling of immunoglobulin uptake by N,N,N',N'-ethylenediaminetetramethylenephosphonic acid-modified zirconia particles under static and dynamic conditions.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050705

• A pilot study of antitumor effect of gallium ethylenediaminetetramethylene phosphonate [Ga(III)-EDTMP] in tumor-bearing rats.

  Advances in therapy 20050101

• Cytotoxic and genotoxic effect of the [166Dy]Dy/166Ho-EDTMP in vivo generator system in mice.

  Nuclear medicine and biology 20041101

• 153 Samarium-EDTMP in myeloablative dosage followed by a second autotransplantation in patients with relapsed multiple myeloma.

  Haematologica 20040901

• Preparation of (166)Dy/(166)Ho-EDTMP: a potential in vivo generator system for bone marrow ablation.

  Nuclear medicine communications 20040601

• Labelling of EDTMP (Multibone) with [111In], [99mTc] and [188Re] using different carriers for 'cross complexation'.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20040501

• Bone lesion detection with carrier-added 99mTc-EDTMP in comparison with 99mTc-DPD.

  Nuclear medicine communications 20040401

• Functional and structural study on chelator-induced suppression of S2/S1 FTIR spectrum in photosynthetic oxygen-evolving complex.

  Journal of inorganic biochemistry 20031001

• Evaluation of a freeze-dried kit for EDTMP-based bone-seeking radiopharmaceuticals.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20030401

• Interaction of immunoglobulin G with N,N,N',N'-ethylenediaminetetramethylenephosphonic acid-modified zirconia.

  Journal of chromatography. A 20030307

• Environmental risk assessment of phosphonates, used in domestic laundry and cleaning agents in The Netherlands.

  Chemosphere 20020501

• Determination of strong binding chelators and their metal complexes by anion-exchange chromatography and inductively coupled plasma mass spectrometry.

  Journal of chromatography. A 20020222

• 177Lu labelled polyaminophosphonates as potential agents for bone pain palliation.

  Nuclear medicine communications 20020101

• Preparation and biological evaluation of 188Re-ethylenediamine-N,N,N',N'-tetrakis(methylene phosphonic acid) as a potential agent for bone pain palliation.

  Nuclear medicine communications 20020101

• [153Sm-EDTMP in a patient suffering from colon cancer with bone metastasis].

  Revista espanola de medicina nuclear 20010401