1432660-47-3 | 1-[5-(Cyclopropylsulfamoyl)-2-(thiophen-3-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea

Packsize	Purity	Availability	Price	Discounted Price
1mg	≥98%	in stock	$57.00	$40.00
5mg	≥98%	in stock	$144.00	$101.00
10mg	98% by HPLC	in stock	$239.00	$168.00
25mg	98% by HPLC	in stock	$442.00	$310.00
50mg	98% by HPLC	in stock	$713.00	$499.00
100mg	98% by HPLC	in stock	$1,192.00	$835.00
500mg	98% by HPLC	in stock	$3,722.00	$2,605.00
1000mg	98% by HPLC	in stock	$5,922.00	$4,145.00

Description

• Catalog Number: AE35573
• Chemical Name: 1-[5-(Cyclopropylsulfamoyl)-2-(thiophen-3-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
• CAS Number: 1432660-47-3
• Molecular Formula: C21H18F3N3O3S2
• Molecular Weight: 481.5111
• MDL Number: MFCD26097285
• SMILES: O=C(Nc1cc(ccc1c1ccsc1)S(=O)(=O)NC1CC1)Nc1cccc(c1)C(F)(F)F

Computed Properties

• Complexity: 771
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 6
• XLogP3: 4.2

Literature

• Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.

  The Journal of biological chemistry 20150109