-
Reversal of oxidative stress by histamine H₃ receptor-ligands in experimental models of schizophrenia.
Arzneimittel-Forschung 20120501
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Histamine H₃ receptors modulate depolarization-evoked [³H]-noradrenaline release from rat olfactory bulb slices.
Neuropharmacology 20120201
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Histamine 3 receptor activation reduces the expression of neuronal angiotensin II type 1 receptors in the heart.
The Journal of pharmacology and experimental therapeutics 20120101
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Deletion and down-regulation of HRH4 gene in gastric carcinomas: a potential correlation with tumor progression.
PloS one 20120101
-
Protective effects of histamine H3-receptor ligands in schizophrenic behaviors in experimental models.
Pharmacological reports : PR 20120101
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Histamine h3 receptor: a novel therapeutic target in alcohol dependence?
Frontiers in systems neuroscience 20120101
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Integrative role of the histaminergic system in feeding and taste perception.
Frontiers in systems neuroscience 20120101
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Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.
Journal of medicinal chemistry 20111208
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The H4 histamine receptor agonist, clobenpropit, suppresses human cholangiocarcinoma progression by disruption of epithelial mesenchymal transition and tumor metastasis.
Hepatology (Baltimore, Md.) 20111101
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Role of H4 receptor in histamine-mediated responses in human melanoma.
Melanoma research 20111001
-
Regulation of ERK2 phosphorylation by histamine in splenocytes.
Immunopharmacology and immunotoxicology 20110601
-
N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands.
Bioorganic & medicinal chemistry 20110501
-
Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.
Molecular pharmacology 20110401
-
Histamine H(3) receptor-mediated modulation of perivascular nerve transmission in rat mesenteric arteries.
European journal of pharmacology 20110325
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Beneficial interaction between clobenpropit and pyridoxine in prevention of electroshock-induced seizures in mice: lack of histaminergic mechanisms.
Human & experimental toxicology 20110101
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Modulation of hematopoiesis through histamine receptor signaling.
Frontiers in bioscience (Scholar edition) 20110101
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Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression.
BMC cancer 20110101
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Histaminergic mechanisms for modulation of memory systems.
Neural plasticity 20110101
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Comparison of the pharmacological properties of human and rat histamine H(3)-receptors.
Biochemical pharmacology 20101101
-
Investigation of 4-piperidinols as novel H3 antagonists.
Bioorganic & medicinal chemistry letters 20101101
-
Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection.
Journal of psychopharmacology (Oxford, England) 20100601
-
Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
The Journal of pharmacology and experimental therapeutics 20100601
-
The H3 receptor antagonist clobenpropit protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells.
Die Pharmazie 20100401
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Modeling G protein-coupled receptors for structure-based drug discovery using low-frequency normal modes for refinement of homology models: application to H3 antagonists.
Proteins 20100201
-
R-(-)-alpha-methylhistamine, a histamine H3 receptor agonist, induces endothelium-dependent vasodilation in rat mesenteric resistance arteries.
Biological & pharmaceutical bulletin 20100101
-
Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.
Bioorganic & medicinal chemistry letters 20091201
-
[Effects of clobenpropit and histidine on reinstatement of morphine-induced conditioned place preference].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20091101
-
The histamine H receptor as a new target for treatment of canine inflammatory skin diseases.
Veterinary dermatology 20091001
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Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.
Bioorganic & medicinal chemistry letters 20090801
-
Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.
Bioorganic & medicinal chemistry 20090601
-
The histamine H4 receptor is functionally expressed on T(H)2 cells.
The Journal of allergy and clinical immunology 20090301
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The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.
Behavioural pharmacology 20090301
-
Histamine H4 receptor antagonism reduces hapten-induced scratching behaviour but not inflammation.
Experimental dermatology 20090101
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H4 histamine receptors mediate cell cycle arrest in growth factor-induced murine and human hematopoietic progenitor cells.
PloS one 20090101
-
Histamine H4 receptors modulate dendritic cell migration through skin--immunomodulatory role of histamine.
Allergy 20081001
-
Electrophysiology-based analysis of human histamine H(4) receptor pharmacology using GIRK channel coupling in Xenopus oocytes.
European journal of pharmacology 20080904
-
Apomorphine-induced turning behavior in 6-hydroxydopamine lesioned rats is increased by histidine and decreased by histidine decarboxylase, histamine H1 and H2 receptor antagonists, and an H3 receptor agonist.
Pharmacology, biochemistry, and behavior 20080901
-
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
International immunopharmacology 20080801
-
Human inflammatory dendritic epidermal cells express a functional histamine H4 receptor.
The Journal of investigative dermatology 20080701
-
Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
Journal of medicinal chemistry 20080612
-
Zebrafish: An in vivo model for the study of neurological diseases.
Neuropsychiatric disease and treatment 20080601
-
4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
Journal of medicinal chemistry 20080522
-
Comparison of the effect of an H(3)-inverse agonist on energy intake and hypothalamic histamine release in normal mice and leptin resistant mice with high fat diet-induced obesity.
Behavioural brain research 20080409
-
Efficient approaches to S-alkyl-N-alkylisothioureas: syntheses of histamine H3 antagonist clobenpropit and its analogues.
The Journal of organic chemistry 20080321
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Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells.
Cellular and molecular neurobiology 20080201
-
The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.
Cancer biology & therapy 20080101
-
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells.
BMC pharmacology 20080101
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Histamine-induced itch and its relationship with pain.
Molecular pain 20080101
-
Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptors.
The Journal of physiology 20070901
-
Histamine downregulates monocyte CCL2 production through the histamine H4 receptor.
The Journal of allergy and clinical immunology 20070801
-
The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes.
European journal of pharmacology 20070719
-
Histamine H4 receptor agonists have more activities than H4 agonism in antigen-specific human T-cell responses.
Immunology 20070601
-
The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons.
European journal of pharmacology 20070601
-
Histamine H3-receptor agonists and imidazole-based H3-receptor antagonists can be thermodynamically discriminated.
British journal of pharmacology 20070601
-
Correlation of apparent affinity values from H3-receptor binding assays with apparent affinity (pKapp) and intrinsic activity (alpha) from functional bioassays.
British journal of pharmacology 20070501
-
Role of histamine in ghrelin-induced gastroprotection against acute gastric lesions.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070401
-
Histamine augments beta2-adrenoceptor-induced cyclic AMP accumulation in human prostate cancer cells DU-145 independently of known histamine receptors.
Biochemical pharmacology 20070315
-
[Reversing effect of histamine on neurotoxicity induced by beta-amyloid1-42].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20070301
-
Pre-synaptic histamine H3 receptors regulate glutamate, but not GABA release in rat thalamus.
Neuropharmacology 20070201
-
Role of apolipoprotein E in anxiety.
Neural plasticity 20070101
-
STAT1 phosphorylation and cleavage is regulated by the histamine (H4) receptor in human atopic and non-atopic lymphocytes.
International immunopharmacology 20061001
-
Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway.
Neuropharmacology 20060901
-
Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.
British journal of pharmacology 20060701
-
Effect of endogenous histamine in the ventral hippocampus on fear memory deficits induced by scopolamine as evaluated by step-through avoidance response in rats.
Physiology & behavior 20060415
-
Histamine excites neonatal rat sympathetic preganglionic neurons in vitro via activation of H1 receptors.
Journal of neurophysiology 20060401
-
Probing the importance of N-glycosylation for [(3)H] clobenpropit binding to human H (3) receptors expressed in HEK 293 cells . 3. Molecular and chemical aspects of the histamine receptors.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401
-
Role of substance P on histamine H(3) antagonist-induced scratching behavior in mice.
Journal of pharmacological sciences 20060401
-
N-(4-Trifluoromethylphenyl)amide group of the synthetic histamine receptor agonist inhibits nicotinic acetylcholine receptor-mediated catecholamine secretion.
Biochemical pharmacology 20060227
-
Histamine increases sickle erythrocyte adherence to endothelium.
British journal of haematology 20060201
-
Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125
-
Effects of intracerebroventricular administration of ultra low doses of histaminergic drugs on morphine state-dependent memory of passive avoidance in mice.
Behavioural brain research 20060106
-
Histamine (H3) receptors modulate the excitatory amino acid receptor response of the vestibular afferents.
Brain research 20051207
-
Cross state-dependent retrieval between histamine and lithium.
Physiology & behavior 20050915
-
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
The Journal of pharmacology and experimental therapeutics 20050901
-
G protein-dependent pharmacology of histamine H3 receptor ligands: evidence for heterogeneous active state receptor conformations.
The Journal of pharmacology and experimental therapeutics 20050701
-
Histamine-3 receptor antagonists reduce superoxide anion generation and lipid peroxidation in rat brain homogenates.
The Journal of pharmacy and pharmacology 20050601
-
Generation of cell lines for drug discovery through random activation of gene expression: application to the human histamine H3 receptor.
Assay and drug development technologies 20050601
-
Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 20050501
-
Influence of intracerebroventricular administration of histaminergic drugs on morphine state-dependent memory in the step-down passive avoidance test.
Pharmacology 20050501
-
Effect of combined histamine H1 and H3 receptor blockade on cutaneous microvascular permeability elicited by compound 48/80.
Life sciences 20050304
-
Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists.
Asian Pacific journal of allergy and immunology 20050301
-
2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists.
Journal of medicinal chemistry 20050113
-
Histamine H3 receptors modulate reactive hyperemia in rat gut.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901
-
Histamine H3 receptor activation inhibits dopamine D1 receptor-induced cAMP accumulation in rat striatal slices.
Neuroscience letters 20040708
-
Presynaptic cannabinoid CB(1) receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats.
British journal of pharmacology 20040601
-
Ligand identification for G-protein-coupled receptors: a lead generation perspective.
Current opinion in chemical biology 20040601
-
1-alkyl-4-acylpiperazines as a new class of imidazole-free histamine H(3) receptor antagonists.
Journal of medicinal chemistry 20040520
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Effect of the histamine H3-antagonist clobenpropit on spatial memory deficits induced by MK-801 as evaluated by radial maze in Sprague-Dawley rats.
Behavioural brain research 20040505
-
Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice.
British journal of pharmacology 20040501
-
Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation.
British journal of pharmacology 20040501
-
[Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040501
-
Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia.
Methods and findings in experimental and clinical pharmacology 20040501
-
Histamine h3 receptor antagonists potentiate methamphetamine self-administration and methamphetamine-induced accumbal dopamine release.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040401
-
Inhibitory effect of iodophenpropit, a selective histamine H3 antagonist, on amygdaloid kindled seizures.
Brain research bulletin 20040315
-
Involvement of central and peripheral histamine H(3) receptors in the control of the vascular tone and oxygen uptake in the mesenteric circulation of the rat.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040301
-
Activation of histamine H3 receptors in human nasal mucosa inhibits sympathetic vasoconstriction.
European journal of pharmacology 20040119
-
Effects of clobenpropit on pentylenetetrazole-kindled seizures in rats.
European journal of pharmacology 20031215
-
Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor.
British journal of pharmacology 20031101
-
Histamine H3 receptors regulate vascular permeability changes in the skin of mast cell-deficient mice.
International immunopharmacology 20031101
-
Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats.
Pharmacology 20030901
-
Involvement of histamine H3 receptors in scratching behaviour in mast cell-deficient mice.
The British journal of dermatology 20030701
-
Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.
The Journal of pharmacology and experimental therapeutics 20030601
-
An in vitro study of histamine on the pulmonary artery of the Wistar-Kyoto and spontaneously hypertensive rats.
European journal of pharmacology 20030530
-
Molecular and pharmacological characterization of the mouse histamine H3 receptor.
European journal of pharmacology 20030425
-
Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
Journal of medicinal chemistry 20030410
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Replacement of imidazole by a piperidine moiety differentially affects the potency of histamine H3-receptor antagonists.
Naunyn-Schmiedeberg's archives of pharmacology 20030101
-
Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels.
BMC neuroscience 20030101
-
Coordination of histamine H3 receptor antagonists with human adrenal cytochrome P450 enzymes.
Pharmacology 20021101
-
Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.
British journal of pharmacology 20021101
-
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
European journal of pharmacology 20021018
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Histamine H3 receptor activation inhibits neurogenic sympathetic vasoconstriction in porcine nasal mucosa.
European journal of pharmacology 20021011
-
Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells.
The Journal of pharmacology and experimental therapeutics 20021001
-
Ligands for histamine H(3) receptors modulate cell proliferation and migration in rat oxyntic mucosa.
British journal of pharmacology 20020901
-
Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model.
Pharmacology, biochemistry, and behavior 20020601
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Presynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway.
Molecular pharmacology 20020101
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Identification of a histamine H4 receptor on human eosinophils--role in eosinophil chemotaxis.
Journal of receptor and signal transduction research 20020101
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Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.
The Journal of pharmacology and experimental therapeutics 20011201
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Dynamics of histamine H(3) receptor antagonists on brain histamine metabolism: do all histamine H(3) receptor antagonists act at a single site?
European journal of pharmacology 20011116
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Histamine H3 receptor-mediated impairment of contextual fear conditioning and in-vivo inhibition of cholinergic transmission in the rat basolateral amygdala.
The European journal of neuroscience 20011101
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Involvement of central histamine in amygdaloid kindled seizures in rats.
Behavioural brain research 20011015
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Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
The Journal of pharmacology and experimental therapeutics 20011001
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Histaminergic modulation of GABAergic transmission in rat ventromedial hypothalamic neurones.
The Journal of physiology 20010801
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[Identification and characterization of histamine H4 receptor].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010701
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Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010601
-
Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.
Journal of medicinal chemistry 20010524
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Histamine H3 receptor-mediated inhibition of sympathetically evoked mydriasis in rats.
European journal of pharmacology 20010504
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Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.
British journal of pharmacology 20010501
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[Role of central histamine in amygdaloid kindled seizures].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010501
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Genomic organization and characterization of splice variants of the human histamine H3 receptor.
The Biochemical journal 20010415
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Different antagonist binding properties of human and rat histamine H3 receptors.
Bioorganic & medicinal chemistry letters 20010409
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Novel histamine H(3)-receptor antagonists and partial agonists with a non-aminergic structure.
British journal of pharmacology 20010401
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Effect of clobenpropit on regional cerebral blood flow in rat hippocampus.
Acta pharmacologica Sinica 20010401
-
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.
Molecular pharmacology 20010301
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Cloning and characterization of a novel human histamine receptor.
The Journal of pharmacology and experimental therapeutics 20010301
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H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways.
Naunyn-Schmiedeberg's archives of pharmacology 20010201
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The rat H3 receptor: gene organization and multiple isoforms.
Biochemical and biophysical research communications 20010112
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Cortical acetylcholine release elicited by stimulation of histamine H1 receptors in the nucleus basalis magnocellularis: a dual-probe microdialysis study in the freely moving rat.
The European journal of neuroscience 20010101
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Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.
British journal of pharmacology 20001201
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Identification of a histamine H(3)-like receptor in the zebrafish (Danio rerio) brain.
Journal of neurochemistry 20000801
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Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.
The Journal of pharmacology and experimental therapeutics 20000601
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Effects of histamine H3 receptor agonists and antagonists on cognitive performance and scopolamine-induced amnesia.
Behavioural brain research 19991001
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Histamine inhibits the production of interleukin-12 through interaction with H2 receptors.
The Journal of clinical investigation 19981115
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Effect of interleukin-1beta on the ascending and descending reflex in rat small intestine.
European journal of pharmacology 19981023
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Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.
Naunyn-Schmiedeberg's archives of pharmacology 19970201
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Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian hamster.
Endocrinology
