14984-68-0 | Cloperastine hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
10mg	95%	in stock	$6.00	$4.00
1g	98%(HPLC)	in stock	$47.00	$33.00
5g	>97.0%(T)(HPLC)	in stock	$74.00	$52.00
25g	>97.0%(T)(HPLC)	in stock	$242.00	$169.00

Description

• Catalog Number: AA75043
• Chemical Name: Cloperastine hydrochloride
• CAS Number: 14984-68-0
• Molecular Formula: C20H25Cl2NO
• Molecular Weight: 366.3246
• MDL Number: MFCD00079012
• SMILES: Clc1ccc(cc1)C(c1ccccc1)OCCN1CCCCC1.Cl
• NSC Number: 758635

Computed Properties

• Complexity: 318
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 6
• Undefined Atom Stereocenter Count: 1

Literature

• Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol.

  Environmental toxicology 20140201

• Development of chromatographic methods for the determination of genotoxic impurities in cloperastine fendizoate.

  Journal of pharmaceutical and biomedical analysis 20120305

• Cloperastine-based cough syrup and acute dystonic reactions.

  Developmental medicine and child neurology 20120301

• [Is the GIRK channel a possible target in the development of a novel therapeutic drug of urinary disturbance?].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110401

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.

  Antimicrobial agents and chemotherapy 20100901

• [Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100501

• Simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma by liquid chromatography-tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20100205

• Ameliorating effects of cloperastine on dysfunction of the urinary bladder caused by cerebral infarction in conscious rats.

  Canadian journal of physiology and pharmacology 20091101

• Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparations.

  International journal of pharmaceutics 20070420

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents.

  Drugs under experimental and clinical research 20040101