-
Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study.
Journal of peptide science : an official publication of the European Peptide Society 20141101
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Upregulated copper transporters in hypoxia-induced pulmonary hypertension.
PloS one 20140101
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MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-mesenchymal transition (EMT) phenotype and are highly invasive in vitro.
The Journal of biological chemistry 20131018
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Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma.
Head & neck 20130201
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Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice.
Hypertension research : official journal of the Japanese Society of Hypertension 20121101
-
Changes in lysyl oxidase (LOX) distribution and its decreased activity in keratoconus corneas.
Experimental eye research 20121101
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The role of lysyl oxidase family members in the stabilization of abdominal aortic aneurysms.
American journal of physiology. Heart and circulatory physiology 20121015
-
LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma.
Ophthalmology 20120901
-
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.
Breast cancer research and treatment 20120801
-
Factor XIIIA transglutaminase expression and secretion by osteoblasts is regulated by extracellular matrix collagen and the MAP kinase signaling pathway.
Journal of cellular physiology 20120701
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Fibroblasts--a key host cell type in tumor initiation, progression, and metastasis.
Upsala journal of medical sciences 20120501
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Effect of defective collagen synthesis on epithelial implant interface: lathyritic model in dogs. An experimental preliminary study.
The Journal of oral implantology 20120401
-
The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation.
The Journal of biological chemistry 20120127
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Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation.
PloS one 20120101
-
Variations in LOXL1 associated with exfoliation glaucoma do not affect amine oxidase activity.
Molecular vision 20120101
-
Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts.
PloS one 20120101
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Triarylmethanes, a new class of cx50 inhibitors.
Frontiers in pharmacology 20120101
-
Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral.
Bone 20111201
-
Lysyl oxidase regulates MMTV promoter: indirect evidence of histone H1 involvement.
Biochemistry and cell biology = Biochimie et biologie cellulaire 20111201
-
Methods to reduce the contraction of tissue-engineered buccal mucosa for use in substitution urethroplasty.
European urology 20111001
-
Effects of prolonged vaginal distension and β-aminopropionitrile on urinary continence and urethral structure.
Urology 20111001
-
Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans.
The Journal of clinical investigation 20110502
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[Effect of lysyl oxidase on migration and adhesion of human gastric cancer HGC-27 cells in vitro].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110501
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A new unifying hypothesis for lathyrism, konzo and tropical ataxic neuropathy: nitriles are the causative agents.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110301
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Life-long programming implications of exposure to tobacco smoking and nicotine before and soon after birth: evidence for altered lung development.
International journal of environmental research and public health 20110301
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The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin.
Molecular biology reports 20110101
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In vitro modulation of cartilage shape plasticity by biochemical regulation of matrix remodeling.
Tissue engineering. Part A 20110101
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Chromatin supraorganization, mitotic abnormalities and proliferation in cells with increased or down-regulated lox expression: Indirect evidence of a LOX-histone H1 interaction in vivo.
Micron (Oxford, England : 1993) 20110101
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Reciprocal roles of angiotensin II and Angiotensin II Receptors Blockade (ARB) in regulating Cbfa1/RANKL via cAMP signaling pathway: possible mechanism for hypertension-related osteoporosis and antagonistic effect of ARB on hypertension-related osteoporosis.
International journal of molecular sciences 20110101
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The ratio 1660/1690 cm(-1) measured by infrared microspectroscopy is not specific of enzymatic collagen cross-links in bone tissue.
PloS one 20110101
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Lysyl oxidase silencing impairs keratinocyte differentiation in a reconstructed-epidermis model.
Experimental dermatology 20101201
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High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function.
Diabetes 20101201
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Lung interstitial cells during alveolarization.
Korean journal of pediatrics 20101201
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T3 affects expression of collagen I and collagen cross-linking in bone cell cultures.
Biochemical and biophysical research communications 20101112
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In search of a new therapeutic target for the treatment of genetically triggered thoracic aortic aneurysms and cardiovascular conditions: insights from human and animal lathyrism.
Interactive cardiovascular and thoracic surgery 20100901
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Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment.
Nature medicine 20100901
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Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion.
Oncogene 20100708
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Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor.
The Journal of biological chemistry 20100702
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Intracellular lysyl oxidase: effect of a specific inhibitor on nuclear mass in proliferating cells.
Biochemical and biophysical research communications 20100611
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Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of gamma-tocotrienol in breast cancer cells.
Cancer letters 20100528
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The effect of lathyrism on dentin structure of the rat incisors: a morphometric and scanning electron microscopic investigation.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100501
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Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
Hypertension (Dallas, Tex. : 1979) 20100501
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Bleomycin induces upregulation of lysyl oxidase in cultured human fetal lung fibroblasts.
Acta pharmacologica Sinica 20100501
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Lysyl oxidase expression and inhibition in uveal melanoma.
Melanoma research 20100401
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Differential effects of homocysteine and beta aminopropionitrile on preosteoblastic MC3T3-E1 cells.
Bone 20100301
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Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.
British journal of cancer 20100202
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Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer.
Journal of carcinogenesis 20100101
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Experimental models of abdominal aortic aneurysms.
The open cardiovascular medicine journal 20100101
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Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours.
ChemMedChem 20091001
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Comparison of the effects of semicarbazide and beta-aminopropionitrile on the arterial extracellular matrix in the Brown Norway rat.
Toxicology and applied pharmacology 20090915
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Functional consequences of mitochondrial DNA deletions in human skin fibroblasts: increased contractile strength in collagen lattices is due to oxidative stress-induced lysyl oxidase activity.
The American journal of pathology 20090901
-
Reduced collagen biosynthesis is the hallmark of cerebral aneurysm: contribution of interleukin-1beta and nuclear factor-kappaB.
Arteriosclerosis, thrombosis, and vascular biology 20090701
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Sea urchin arylsulfatase, an extracellular matrix component, is involved in gastrulation during embryogenesis.
Development genes and evolution 20090601
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Proteoglycan production is required in initial stages of new cartilage matrix formation but inhibits integrative cartilage repair.
Journal of tissue engineering and regenerative medicine 20090201
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Wound-healing modulation in upper airway stenosis-Myths and facts.
Head & neck 20090101
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The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells.
PloS one 20090101
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Osteitis fibrosa is mediated by Platelet-Derived Growth Factor-A via a phosphoinositide 3-kinase-dependent signaling pathway in a rat model for chronic hyperparathyroidism.
Endocrinology 20081101
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Ultrastructural and histomorphometric alterations of rat jaw bones after experimental induction of lathyrism.
Archives of oral biology 20081001
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Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells.
The Journal of biological chemistry 20080829
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Collagen cross-linking influences osteoblastic differentiation.
Calcified tissue international 20080501
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Contribution of collagen network features to functional properties of engineered cartilage.
Osteoarthritis and cartilage 20080301
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Cartilage growth and remodeling: modulation of balance between proteoglycan and collagen network in vitro with beta-aminopropionitrile.
Osteoarthritis and cartilage 20080101
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Effect of cellular aging on collagen biosynthesis: I. Methodological considerations and pharmacological applications.
Archives of gerontology and geriatrics 20080101
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50 years ago in CORR : skeletal lesions produced by aminonitriles by Ignacio V. Ponseti MD CORR 1957;9:131-144.
Clinical orthopaedics and related research 20080101
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Active lysyl oxidase (LOX) correlates with focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes.
Neuropathology and applied neurobiology 20071201
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Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis.
American journal of physiology. Gastrointestinal and liver physiology 20071201
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Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta.
Drug metabolism and disposition: the biological fate of chemicals 20071001
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Essential role of lysyl oxidases in notochord development.
Developmental biology 20070715
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Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-beta1 effects.
Matrix biology : journal of the International Society for Matrix Biology 20070701
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Distinct steps of cross-linking, self-association, and maturation of tropoelastin are necessary for elastic fiber formation.
Journal of molecular biology 20070608
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Mechanism for covalent binding of rofecoxib to elastin of rat aorta.
The Journal of pharmacology and experimental therapeutics 20070301
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The aminolysis of N-aroyl beta-lactams occurs by a concerted mechanism.
Organic & biomolecular chemistry 20070207
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Bonding of articular cartilage using a combination of biochemical degradation and surface cross-linking.
Arthritis research & therapy 20070101
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Unilateral pedicle screws asymmetric tethering: an innovative method to create idiopathic deformity.
Journal of orthopaedic surgery and research 20070101
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Functional diversity of lysyl hydroxylase 2 in collagen synthesis of human dermal fibroblasts.
Experimental cell research 20061101
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Use of an in vitro model of tissue-engineered skin to investigate the mechanism of skin graft contraction.
Tissue engineering 20061101
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A novel type of lysine oxidase: L-lysine-epsilon-oxidase.
Biochimica et biophysica acta 20061001
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Periodontal & systemic bone changes in rats with experimental lathyrism.
The Indian journal of medical research 20060401
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Investigation of keratinocyte regulation of collagen I synthesis by dermal fibroblasts in a simple in vitro model.
The British journal of dermatology 20060301
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The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model.
Clinical cancer research : an official journal of the American Association for Cancer Research 20060301
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Examination of the stress-induced expression of the collagen binding heat shock protein, hsp47, in Xenopus laevis cultured cells and embryos.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20060101
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Phenotypical and functional characterization of alveolar macrophage subpopulations in the lungs of NO2-exposed rats.
Respiratory research 20060101
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Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism.
Cancer research 20051215
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Collagen and elastin cross-linking: a mechanism of constrictive remodeling after arterial injury.
American journal of physiology. Heart and circulatory physiology 20051101
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Members of the lysyl oxidase family are expressed during the development of the frog Xenopus laevis.
Differentiation; research in biological diversity 20051001
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The Formation of lysine tyrosylquinone (LTQ) is a self-processing reaction. Expression and characterization of a Drosophila lysyl oxidase.
Biochemistry 20050906
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Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2.
Journal of hepatology 20050901
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Kinetics of collagen crosslinking in adult bovine articular cartilage.
Osteoarthritis and cartilage 20050801
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Drosophila lysyl oxidases Dmloxl-1 and Dmloxl-2 are differentially expressed and the active DmLOXL-1 influences gene expression and development.
The Journal of biological chemistry 20050617
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Treatment of cartilage with beta-aminopropionitrile accelerates subsequent collagen maturation and modulates integrative repair.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20050501
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Determination of systemically & locally induced periodontal defects in rats.
The Indian journal of medical research 20050301
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Inhibition of breast adenocarcinoma growth by intratumoral injection of lipophilic long-acting lathyrogens.
Anti-cancer drugs 20050201
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Inhibition of lysyl oxidase activity can delay phenotypic modulation of chondrocytes in two-dimensional culture.
Osteoarthritis and cartilage 20050201
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The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded.
Cardiovascular diabetology 20050101
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Synthesis and evaluation of long-acting D-penicillamine derivatives.
Connective tissue research 20050101
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Effect of bestatin on angiotensin I-, II- and III-induced collagen gel contraction in cardiac fibroblasts.
Journal of the renin-angiotensin-aldosterone system : JRAAS 20041201
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The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.
The Journal of biological chemistry 20040924
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A role for lysyl oxidase regulation in the control of normal collagen deposition in differentiating osteoblast cultures.
Journal of cellular physiology 20040701
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Medical management of superficial digital flexor tendonitis: a comparative study in 219 horses (1992-2000).
Equine veterinary journal 20040701
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The role of ascorbic acid on collagen structure and levels of serum interleukin-6 and tumour necrosis factor-alpha in experimental lathyrism.
Clinical and experimental dermatology 20040301
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Collagen production in cardiac fibroblasts during inhibition of angiotensin-converting enzyme and aminopeptidases.
Journal of hypertension 20040101
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Tropoelastin inhibits vascular calcification via 67-kDa elastin binding protein in cultured bovine aortic smooth muscle cells.
Journal of atherosclerosis and thrombosis 20040101
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The effects of beta-aminopropionitrile on colonic anastomosis in rats.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 20040101
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Expression and purification of enzymatically active forms of the human lysyl oxidase-like protein 4.
The Journal of biological chemistry 20031226
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Effect of dexamethasone on root resorption after delayed replantation of rat tooth.
Journal of endodontics 20031201
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Purification of enzymatically active human lysyl oxidase and lysyl oxidase-like protein from Escherichia coli inclusion bodies.
Protein expression and purification 20031001
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TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice.
Thorax 20030901
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Collagen crosslinking and cell density have distinct effects on fibroblast-mediated contraction of collagen gels.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20030801
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Elastic fiber production in cardiovascular tissue-equivalents.
Matrix biology : journal of the International Society for Matrix Biology 20030601
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Pathological observation of brain arteries and spontaneous aneurysms in hypertensive rats.
Chinese medical journal 20030301
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Chemical and biomechanical characterization of hyperhomocysteinemic bone disease in an animal model.
BMC musculoskeletal disorders 20030101
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Treatment of acute schistosomiasis mansoni with praziquantel and an antifibrotic agent in mice. Maintenance of resistance to infection.
Arzneimittel-Forschung 20030101
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Collagen fibrillogenesis by chondrocytes in alginate.
Tissue engineering 20021201
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Metabolism of tresperimus by rat aorta semicarbazide-sensitive amine oxidase (SSAO).
Fundamental & clinical pharmacology 20021201
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An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats.
Journal of vascular surgery 20021001
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Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall.
Arteriosclerosis, thrombosis, and vascular biology 20020901
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Biochemical and toxicological evaluation of agent-cofactor reactivity as a mechanism of action for osteolathyrism.
Toxicology 20020815
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A molecular role for lysyl oxidase in breast cancer invasion.
Cancer research 20020801
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Regulation of the expression of lysyl oxidase mRNA in cultured rabbit retinal pigment epithelium cells.
Matrix biology : journal of the International Society for Matrix Biology 20020601
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Osteolathyrism in the rat: an X-ray diffraction study of collagen from normal and lathyritic rats. 1964.
Academic radiology 20020501
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Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
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Integrative articular cartilage repair: dependence on developmental stage and collagen metabolism.
Osteoarthritis and cartilage 20020301
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Effect of beta-aminopropionitrile and hyaluronic acid on repair of collagenase-induced injury of the rabbit Achilles tendon.
Journal of comparative pathology 20020101
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Effects of hydrocortisone and beta-aminopropionitrile on stress-strain and stress-relaxation behaviors, and birefringent retardation of collagen fibers in the rat incisor periodontal ligament.
Connective tissue research 20020101
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[Granular media calcinosis of the aorta. Structural findings, historical review and pathogenetic significance].
Zeitschrift fur Kardiologie 20011201
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Beta-aminopropionitrile treatment can accelerate recovery of mice after spinal cord injury.
European journal of pharmacology 20011026
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Effects of beta-aminopropionitrile on equine tendon metabolism in vitro and on effects of insulin-like growth factor-I on matrix production by equine tenocytes.
American journal of veterinary research 20011001
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Force deficits after stretches of activated rat muscle-tendon complex with reduced collagen cross-linking.
European journal of applied physiology 20010901
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Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage.
The Journal of biological chemistry 20010629
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Building Elastin. Incorporation of recombinant human tropoelastin into extracellular matrices using nonelastogenic rat-1 fibroblasts as a source for lysyl oxidase.
American journal of respiratory cell and molecular biology 20010601
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Amine oxidase-like activity of polyphenols. Mechanism and properties.
European journal of biochemistry 20010401
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Characterization of a model compound for the lysine tyrosylquinone cofactor of lysyl oxidase.
Biochemical and biophysical research communications 20010216
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Experimental copper deficiency, chromium deficiency and additional molybdenum supplementation in goats--pathological findings.
Acta veterinaria Scandinavica 20010101
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Teratological studies on craniofacial malformations.
Swedish dental journal. Supplement 19970101
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The effect of beta-aminopropionitrile on elastin gene expression in smooth muscle cell cultures.
Biochemical and biophysical research communications 19910916
