153-78-6 | 2-Aminofluorene

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$21.00	$15.00
10g	98%	in stock	$29.00	$20.00
25g	98%	in stock	$46.00	$32.00
100g	98%	in stock	$165.00	$116.00
500g	98%	in stock	$800.00	$560.00

Description

• Catalog Number: AB61202
• Chemical Name: 2-Aminofluorene
• CAS Number: 153-78-6
• Molecular Formula: C13H11N
• Molecular Weight: 181.2331
• MDL Number: MFCD08459291
• SMILES: Nc1ccc2-c3c(Cc2c1)cccc3

Computed Properties

• Complexity: 213
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: 3.1

Literature

• In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding.

  Toxicology in vitro : an international journal published in association with BIBRA 20170401

• Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites.

  Archives of toxicology 20151201

• Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1.

  Chemical research in toxicology 20130617

• Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance.

  Chemical research in toxicology 20120820

• The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat.

  Experimental and molecular pathology 20120801

• Protective effect of Enicostema axillare on mutagenicity of Salmonella typhimurium by increasing free radical scavenging abilities.

  Pharmaceutical biology 20120601

• Synthesis, study on anti-arthritic, anti-inflammatory activity and toxicity of some novel bis-oxy cyclophane diamides.

  Bioorganic & medicinal chemistry letters 20120601

• Roles of human sulfotransferases in genotoxicity of carcinogens using genetically engineered umu test strains.

  Environmental and molecular mutagenesis 20120301

• Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice.

  PloS one 20120101

• [The role of metabolic activation of promutagens in the genome destabilization under pheromonal stress in the house mouse (Mus musculus)].

  Genetika 20111001

• Carbon black nanoparticles impair acetylation of aromatic amine carcinogens through inactivation of arylamine N-acetyltransferase enzymes.

  ACS nano 20110628

• Antimutagenic and antioxidant characteristics of Chukrasia tabularis A Juss extracts.

  International journal of toxicology 20110201

• Pulmonary cytochrome P450 enzymes belonging to the CYP4B subfamily from an Australian marsupial, the tammar wallaby (Macropus eugenii).

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110101

• Incorporation of 3-aminobenzanthrone into 2'-deoxyoligonucleotides and its impact on duplex stability.

  Journal of nucleic acids 20110101

• Broad spectrum antimutagenic activity of antioxidant active fraction of punica granatum L. peel extracts.

  Mutation research 20101221

• Cadmium alters the biotransformation of carcinogenic aromatic amines by arylamine N-acetyltransferase xenobiotic-metabolizing enzymes: molecular, cellular, and in vivo studies.

  Environmental health perspectives 20101201

• Antimutagenic potential of glucosinolate-rich seed extracts of broccoli (Brassica oleracea L var italica Plenck).

  International journal of toxicology 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Biosynthesis and characterization of organosoluble conjugated poly(2-aminofluorene) with the pyrazine bridged.

  Biomacromolecules 20101011

• Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet).

  Chemico-biological interactions 20100805

• Antioxidant and antimutagenic activity of Carum copticum fruit extracts.

  Toxicology in vitro : an international journal published in association with BIBRA 20100601

• Nuclear factor-kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis.

  Journal of gastroenterology and hepatology 20100401

• Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.

  Nature structural & molecular biology 20100301

• Enthalpy-entropy contribution to carcinogen-induced DNA conformational heterogeneity.

  Biochemistry 20100119

• Effect of antisense oligomer in controlling c-raf.1 overexpression during diethylnitrosamine-induced hepatocarcinogenesis in rat.

  Cancer chemotherapy and pharmacology 20100101

• Modulatory role of alizarin from Rubia cordifolia L. against genotoxicity of mutagens.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Mutagenicity of new lead compounds to treat sickle cell disease symptoms in a Salmonella/microsome assay.

  International journal of molecular sciences 20100101

• Cellular proliferation, cell death, and liver histology in Gambusia affinis after dietary exposure to benzidine and 2-aminofluorene.

  International journal of toxicology 20100101

• Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea.

  BMC complementary and alternative medicine 20100101

• DNA polymerase: structural homology, conformational dynamics, and the effects of carcinogenic DNA adducts.

  Journal of nucleic acids 20100101

• Anti- and pro-mutagenic effects of silymarin in the Ames bacterial reverse mutation assay.

  Phytotherapy research : PTR 20091001

• Screening for reactive metabolites using electro-optical arrays featuring human liver cytosol and microsomal enzyme sources and DNA.

  Chemical communications (Cambridge, England) 20090928

• Mutagenicity of aromatic amines and amides with chemical models for cytochrome P450 in Ames assay.

  Toxicology in vitro : an international journal published in association with BIBRA 20090901

• Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta.

  Biochemistry 20090519

• Influence of water hydrogen bonding on the reactions of arylnitrenium ions with guanosine: hydrogen-bonding effects can favor reaction at the C8 site.

  The journal of physical chemistry. B 20090507

• Kinetics of deoxy-CTP incorporation opposite a dG-C8-N-2-aminofluorene adduct by a high-fidelity DNA polymerase.

  Journal of molecular biology 20090306

• A stable and sensitive testing system for potential carcinogens based on DNA damage-induced gene expression in human HepG2 cell.

  Toxicology in vitro : an international journal published in association with BIBRA 20090201

• Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis.

  Journal of molecular histology 20090201

• 4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.

  Toxicological sciences : an official journal of the Society of Toxicology 20090101

• Mutagenicity of Chinese traditional medicine Semen Armeniacae amarum by two modified Ames tests.

  BMC complementary and alternative medicine 20090101

• Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.

  Journal of parasitology research 20090101

• Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole.

  Interdisciplinary toxicology 20081201

• Possible relationship between the risk of Japanese bladder cancer cases and the CYP4B1 genotype.

  Japanese journal of clinical oncology 20080901

• High-throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 1. Evidence for an ortho effect on the fragmentation of 4-benzenesulfinyl-3-methylphenylamine using electrospray ionisation mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20080801

• Mutagenicity and antimutagenicity of teas used in popular medicine in the salmonella/microsome assay.

  Toxicology in vitro : an international journal published in association with BIBRA 20080601

• Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.

  Biochemical pharmacology 20080401

• Electrochemical genotoxicity screening for arylamines bioactivated by N-acetyltransferase.

  Analytical chemistry 20080215

• Fluorescence probing of aminofluorene-induced conformational heterogeneity in DNA duplexes.

  Chemical research in toxicology 20080201

• Antigenotoxic effect of extract from Cynara cardunculus L.

  Phytotherapy research : PTR 20080101

• Determination of genotoxic, antigenotoxic and cytotoxic potential of the extract from lichen Cetraria aculeata (Schreb.) Fr. in vitro.

  Phytotherapy research : PTR 20080101

• Effects of luteolin on distribution and metabolism of 2-aminofluorene in male Sprague-Dawley rats.

  In vivo (Athens, Greece) 20080101

• Modulation of energy metabolic enzyme expression in N-nitrosodiethylamine-mediated hepatocarcinogenesis by Chinese herbs, Huqi San.

  BioFactors (Oxford, England) 20080101

• Solvent effects on intermolecular proton transfer: the rates of nitrene protonation and their correlation with Swain acity.

  Organic letters 20071206

• The metabolic activation of 2-aminofluorine, 4-aminobiphenyl, and benzidine by cytochrome P-450-107S1 of Pseudomonas aeruginosa.

  Toxicology in vitro : an international journal published in association with BIBRA 20071201

• Probing the sequence effects on NarI-induced -2 frameshift mutagenesis by dynamic 19F NMR, UV, and CD spectroscopy.

  Biochemistry 20071120

• Time-resolved resonance Raman investigation of the 2-fluorenylnitrenium ion reactions with C8 guanosine derivatives.

  The journal of physical chemistry. B 20071108

• Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells.

  Chemical research in toxicology 20071101

• Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse.

  Drug metabolism and disposition: the biological fate of chemicals 20070701

• The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test.

  Mutation research 20070518

• Time-resolved resonance Raman study of the reaction of the 2-fluorenylnitrenium ion with 2-fluorenylazide.

  The journal of physical chemistry. A 20070301

• Conformation-specific recognition of carcinogen-DNA adduct in escherichia coli nucleotide excision repair.

  Chemical research in toxicology 20070101

• Effects of oral administration of berberine on distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats.

  In vivo (Athens, Greece) 20070101

• Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by Benzo(alpha)pyrene and 2-aminofluorene metabolites.

  Immunopharmacology and immunotoxicology 20070101

• Predicting drug metabolism-dependent toxicity for humans with a genetically engineered cell battery.

  Alternatives to laboratory animals : ATLA 20061201

• Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5.

  Toxicology 20061110

• In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice.

  Drug metabolism and disposition: the biological fate of chemicals 20061001

• Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2.

  The Journal of pharmacology and experimental therapeutics 20061001

• Stoichiometrically different inclusion complexes of 2-aminofluorene and 2-amino-9-hydroxyfluorene in beta-cyclodextrin: a spectrofluorimetric study.

  Journal of fluorescence 20060901

• Induced circular dichroism characteristics as conformational probes for carcinogenic aminofluorene-DNA adducts.

  Chemical research in toxicology 20060801

• Fluorimetric study on molecular recognition of beta-cyclodextrin with 2-amino-9-fluorenone.

  Journal of fluorescence 20060701

• Microbial transformation of aniline derivatives: regioselective biotransformation and detoxification of 2-phenylenediamine by Bacillus cereus strain PDa-1.

  Journal of bioscience and bioengineering 20060701

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• A battery of in vivo and in vitro tests useful for genotoxic pollutant detection in surface waters.

  Aquatic toxicology (Amsterdam, Netherlands) 20060420

• Metabolic activation of bladder procarcinogens, 2-aminofluorene, 4-aminobiphenyl, and benzidine by Pseudomonas aeruginosa and other human endogenous bacteria.

  Toxicology in vitro : an international journal published in association with BIBRA 20060401

• Study on the mutagenicity and antimutagenicity of beta-ionone in the Salmonella/microsome assay.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060401

• Solvent effects on the reactivity of fluorenyl nitrenium ion with DNA-like probes.

  Biophysical chemistry 20060201

• Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.

  PLoS biology 20060101

• The role of Ca2+ in (-)-menthol-induced human promyelocytic leukemia HL-60 cell death.

  In vivo (Athens, Greece) 20060101

• Ketoprofen-inhibited N-acetyltransferase activity and gene expression in human colon tumor cells.

  Anticancer research 20060101

• Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2).

  Melanoma research 20051201

• Heterologous co-expression of human cytochrome P450 1A2 and polymorphic forms of N-acetyltransferase 2 for studies on aromatic amines in V79 Chinese hamster cells.

  Alternatives to laboratory animals : ATLA 20051201

• New fluorophores based on trifluorenylamine with very large intrinsic three-photon absorption cross sections.

  Organic letters 20051027

• Berberine inhibits arylamine N-acetyltransferase activity and gene expression in Salmonella typhi.

  Current microbiology 20051001

• Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin.

  Drug metabolism and disposition: the biological fate of chemicals 20050901

• Evaluation of mutagenic and antimutagenic activities of alpha-bisabolol in the Salmonella/microsome assay.

  Mutation research 20050801

• Oral administration of paclitaxel affects the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20050801

• Diallyl disulfide inhibits N-acetyltransferase activity and gene expression in human esophagus epidermoid carcinoma CE 81T/VGH cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050701

• Time-resolved resonance Raman observation of the 2-fluorenylnitrenium ion reaction with guanosine to form a C8 intermediate.

  Journal of the American Chemical Society 20050615

• Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes.

  Toxicology 20050601

• Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.

  Mutagenesis 20050501

• Incorporation of N2-deoxyguanosine metabolic adducts of 2-aminonaphthalene and 2-aminofluorene into oligomeric DNA.

  Chemical research in toxicology 20050301

• Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1.

  The protein journal 20050201

• Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase.

  The Biochemical journal 20050115

• Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening.

  Biochemical pharmacology 20050115

• Effects of ellagic acid by oral administration on distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats.

  In vivo (Athens, Greece) 20050101

• Ellagic acid inhibits growth and arylamine N-acetyltransferase activity and gene expression in Staphylococcus aureus.

  In vivo (Athens, Greece) 20050101

• N-acetyltransferase is involved in baicalein-induced N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells.

  In vivo (Athens, Greece) 20050101

• Effects of aspirin on the in vitro and in vivo acetylation of 2-aminofluorene in Sprague-Dawley rats.

  In vivo (Athens, Greece) 20050101

• Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells.

  Anticancer research 20050101

• Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines.

  In vivo (Athens, Greece) 20050101

• Berberine decreased N-acetylation of 2-aminofluorene through inhibition of N-acetyltransferase gene expression in human leukemia HL-60 cells.

  Anticancer research 20050101

• Effects of exposure to diesel exhaust particles (DEP) on pulmonary metabolic activation of mutagenic agents.

  Mutation research 20041212

• Antimutagenicity of coriander (Coriandrum sativum) juice on the mutagenesis produced by plant metabolites of aromatic amines.

  Toxicology letters 20041102

• Evidence for arylamine N-acetyltransferase activity in Klebsiella pneumoniae.

  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20040801

• Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines.

  Chemical research in toxicology 20040401

• Mass spectrometric investigation of the mechanism of inactivation of hamster arylamine N-acetyltransferase 1 by N-hydroxy-2-acetylaminofluorene.

  Chemical research in toxicology 20040301

• Inhibition of N-acetyltransferase activity and gene expression in human colon cancer cell lines by diallyl sulfide.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040201

• Human acetyl CoA:arylamine N-acetyltransferase variants generated by random mutagenesis.

  Molecular pharmacology 20040101

• The inhibition of N-acetyltransferase activity and gene expression in human bladder cancer cells (T24) by shikonin.

  In vivo (Athens, Greece) 20040101

• PCR and flow cytometric analysis of paclitaxel-inhibited arylamine N-acetyltransferase activity and gene expression in human osteogenic sarcoma cells (U-2 OS).

  Anticancer research 20040101

• N-acetyltransferase activity is involved in paclitaxel-induced N-acetylation of 2-aminofluorene in human bladder cancer cells (T24).

  Anticancer research 20040101

• Shikonin inhibits the growth and N-acetylation of 2-aminofluorene in Helicobacter pylori from ulcer patients.

  Anticancer research 20040101

• N-ethylphenyl acetamide (EPA) inhibits DNA synthesis and N-acetylation of 2-aminofluorene in human colon tumor cells (colo 205).

  Anticancer research 20040101

• Paclitaxel inhibits N-acetyltransferase activity and gene expression in human stomach tumor cells (SC-M1).

  Research communications in molecular pathology and pharmacology 20040101

• Gypenosides inhibited N-acetylation of 2-aminofluorene, N-acetyltransferase gene expression and DNA adduct formation in human cervix epithelioid carcinoma cells (HeLa).

  Research communications in molecular pathology and pharmacology 20040101

• Effects of tamoxifen on DNA adduct formation and arylamines N-acetyltransferase activity in human breast cancer cells.

  Research communications in molecular pathology and pharmacology 20040101

• Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease.

  Biochemistry 20031104

• Arylamine N-acetyltransferases: covalent modification and inactivation of hamster NAT1 by bromoacetamido derivatives of aniline and 2-aminofluorene.

  Journal of protein chemistry 20031101

• Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells.

  Leukemia research 20030901

• Neonatal ontogeny of murine arylamine N-acetyltransferases: implications for arylamine genotoxicity.

  Toxicological sciences : an official journal of the Society of Toxicology 20030601

• Curcumin inhibited the arylamines N-acetyltransferase activity, gene expression and DNA adduct formation in human lung cancer cells (A549).

  Toxicology in vitro : an international journal published in association with BIBRA 20030601

• Paclitaxel (taxol) inhibits the arylamine N-acetyltransferase activity and gene expression (mRNA NAT1) and 2-aminofluorene-DNA adduct formation in human bladder carcinoma cells (T24 and TSGH 8301).

  Pharmacology & toxicology 20030601

• Characterization of pulmonary CYP4B2, specific catalyst of methyl oxidation of 3-methylindole.

  Molecular pharmacology 20030501

• Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin.

  Drug metabolism and disposition: the biological fate of chemicals 20030401

• Time-resolved resonance Raman and density functional study of an azirine intermediate in the 2-fluorenylnitrene ring-expansion reaction to form a dehydroazepine product.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030317

• Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster.

  Pharmacogenetics 20030301

• Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay.

  Mutagenesis 20030301

• Mutagenic and antimutagenic potential of the medicinal plants M. laevigata and C. xanthocarpa.

  Phytotherapy research : PTR 20030301

• Studies on correlation of antimutagenic and antiproliferative activities of Juglans regia L.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101

• Bioassay-guided isolation of antimutagenic factors from fruits of Terminalia bellerica.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101

• Luteolin induces N-acetylation and DNA adduct of 2-aminofluorene accompanying N-acetyltransferase activity and gene expression in human bladder cancer T24 cell line.

  Anticancer research 20030101

• Paclitaxel affects the amounts of the N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in Sprague-Dawley rats.

  In vivo (Athens, Greece) 20030101

• N-acetyltransferase is involved in gypenosides-induced N-acetylation of 2-aminofluorene and DNA adduct formation in human cervix epidermoid carcinoma cells (Ca Ski).

  In vivo (Athens, Greece) 20030101

• Curcumin decreases the DNA adduct formation, arylamines N-acetyltransferase activity and gene expression in human colon tumor cells (colo 205).

  In vivo (Athens, Greece) 20030101

• Effects of (-)-menthol on the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats.

  In vivo (Athens, Greece) 20030101

• Deacylation of N-arylformamides and N-arylacetamides by formamidase in rat liver.

  Drug metabolism and disposition: the biological fate of chemicals 20021201

• Antimutagenic effects of black tea (World Blend) and its two active polyphenols theaflavins and thearubigins in Salmonella assays.

  Phytotherapy research : PTR 20021101

• Antimutagenic activities of acetone and methanol fractions of Terminalia arjuna.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

• Quercetin glucuronides inhibited 2-aminofluorene acetylation in human acute myeloid HL-60 leukemia cells.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20021001

• Comments on the history and importance of aromatic and heterocyclic amines in public health.

  Mutation research 20020930

• Metabolic oxidation of carcinogenic arylamines by p450 monooxygenases: theoretical support for the one-electron transfer mechanism.

  Mutation research 20020930

• Berberine inhibited arylamine N-acetyltransferase activity and gene expression and DNA adduct formation in human malignant astrocytoma (G9T/VGH) and brain glioblastoma multiforms (GBM 8401) cells.

  Neurochemical research 20020901

• Chemical models for cytochrome P450 as a biomimetic metabolic activation system in mutation assays.

  Mutation research 20020826

• Functional genomics of C190T single nucleotide polymorphism in human N-acetyltransferase 2.

  Biological chemistry 20020601

• Time-resolved resonance Raman spectroscopy and density functional study of 2-fluorenylnitrene and its dehydroazepine products.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20020503

• The effect of paclitaxel on 2-aminofluorene-DNA adducts formation and arylamine N-acetyltransferase activity and gene expression in human lung tumor cells (A549).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020501

• The effect of paclitaxel on gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020501

• Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents. Part II: alkylation far away from the amino function.

  Mutation research 20020325

• A correlative study on antimutagenic and chemopreventive activity of Acacia auriculiformis A. Cunn. and Acacia nilotica (L.) Willd. Ex Del.

  Drug and chemical toxicology 20020201

• Effects of butylated hydroxyanisole and butylated hydroxytoluene on DNA adduct formation and arylamine N-acetyltransferase activity in human bladder tumour cells.

  Journal of applied toxicology : JAT 20020101

• Antimutagenic and anticarcinogenic effects of Phyllanthus amarus.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020101

• Modulatory effect of phenolic fractions of Terminalia arjuna on the mutagenicity in Ames assay.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20020101

• Preliminary evaluation of the cytotoxic and genotoxic potential of D-003: Mixture of very long chain fatty acids.

  Teratogenesis, carcinogenesis, and mutagenesis 20020101

• Hydrocortisone affects the N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in Sprague-Dawley rats.

  Anticancer research 20020101

• Induction of light emission by luminescent bacteria treated with UV light and chemical mutagens.

  Journal of applied genetics 20020101

• Oral administration of 5-methoxypsoralen affects the distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats.

  In vivo (Athens, Greece) 20020101

• Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in human promyelocytic leukemia cells.

  The American journal of Chinese medicine 20020101

• Reversion mutation in dark variants of luminous bacteria and its application in gene toxicant monitoring.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101

• Activities of cytochrome p450 enzymes in liver and kidney microsomes from systemic carnitine deficiency mice with a gene mutation of carnitine/organic cation transporter.

  Drug metabolism and pharmacokinetics 20020101

• Metabolic activation of three arylamines and two organophosphorus insecticides by coriander (Coriandrum sativum) a common edible vegetable.

  Toxicology letters 20011215

• Leukemia inhibitory factor decreases the arylamine N-acetyltransferase activity in human cumulus granulosa cells.

  Journal of assisted reproduction and genetics 20011201

• Sulindac inhibited gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in T24 human bladder tumor cells.

  Urological research 20011201

• Transient-resonance Raman and density functional theory investigation of 4-biphenylylnitrenium, 2-fluorenylnitrenium, and diphenylnitrenium ions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20011119

• Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents. Part I. Alkylation ortho to the amino function.

  Mutation research 20011115

• Studies on the antimutagenesis of Phyllanthus orbicularis: mechanisms involved against aromatic amines.

  Mutation research 20011115

• N-benzylimidazole for preparation of S9 fraction with multi-induction of metabolizing enzymes in short-term genotoxicity assays.

  Mutagenesis 20011101

• S9 induction by the combined treatment with cyclohexanol and albendazole.

  Mutagenesis 20011101

• Vitamin C inhibited DNA adduct formation and arylamine N-acetyltransferase activity and gene expression in rat glial tumor cells.

  Neurochemical research 20011001

• Kinetics of acetyl coenzyme A: arylamine N-acetyltransferase from rapid and slow acetylator human benign prostatic hyperplasia tissues.

  Urological research 20011001

• CYP1A2 is expressed along with CYP1A1 in the human lung.

  Cancer letters 20010928

• Antimutagenicity and induction of anticarcinogenic phase II enzymes by basidiomycetes.

  Journal of ethnopharmacology 20010901

• Kinetics of acetyl coenzyme A: arylamine N-acetyltransferase from human cumulus cells.

  Journal of assisted reproduction and genetics 20010901

• Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010701

• A transgenic mouse expressing human CYP4B1 in the liver.

  Biochemical and biophysical research communications 20010615

• Inhibitory actions of luteolin on the growth and arylamine N-acetyltransferase activity in strains of Helicobacter pylori from ulcer patients.

  Toxicology in vitro : an international journal published in association with BIBRA 20010601

• Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.

  Mutation research 20010531

• Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms.

  Pharmacogenetics 20010401

• Transient resonance Raman and density functional theory investigation of the 2-fluorenylnitrenium ion.

  Journal of the American Chemical Society 20010321

• CYP1A2 is expressed along with CYP1A1 in the human lung.

  Cancer letters 20010310

• Antimutagenic potential of extracts isolated from Terminalia arjuna.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20010101

• Ellagic acid inhibited 2-aminofluorene and p-aminobenzoic acid acetylation by mononuclear leucocytes from Sprague-Dawley rats.

  Cytobios 20010101

• Luteolin inhibits the growth and arylamine N-acetyl-transferase activity in Neisseria gonorrhoeae.

  Microbios 20010101

• Effect of norcantharidin on N-acetyltransferase activity in HepG2 cells.

  The American journal of Chinese medicine 20010101

• Metabolism of 2-nitrofluorene, 2-aminofluorene and 2-acylaminofluorenes in rat and dog and the role of intestinal bacteria.

  Xenobiotica; the fate of foreign compounds in biological systems 20010101

• Effects of carmustine on aminofluorene-DNA adducts formation in rat glial tumor cells.

  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20010101

• Effects of (-)-menthol on arylamine N-acetyltransferase activity in human liver tumor cells.

  The American journal of Chinese medicine 20010101

• Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons.

  Mutation research 20000323

• Rhein affects arylamine N-acetyltransferase activity in Helicobacter pylori from peptic ulcer patients.

  Journal of applied toxicology : JAT 19980101

• Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation.

  Mutation research 19970801

• p53 protein expression by hepatocarcinogens in the rat liver and its potential role in mitoinhibition of normal hepatocytes as a mechanism of hepatic tumour promotion.

  Carcinogenesis 19970501

• Function and localization of cytochromes P450 involved in the metabolic activation of food-derived heterocyclic amines.

  Princess Takamatsu symposia 19950101

• Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test.

  Mutation research 19931201

• Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.

  Cancer research 19890615

• N-hydroxy-2-acetylaminofluorene as effective inhibitor of aldehyde oxidase.

  Biochemical and biophysical research communications 19860716