-
Mitochondrial Channel Opener Diazoxide Attenuates Hypoxia-Induced sFlt-1 Release in Human Choriocarcinoma Cells.
Journal of menopausal medicine 20140401
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Role of ROS/RhoA/PI3K/PKB signaling in NS1619-mediated blood-tumor barrier permeability increase.
Journal of molecular neuroscience : MN 20120901
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Mitochondrial K+ channels are involved in ischemic postconditioning in rat hearts.
The journal of physiological sciences : JPS 20120701
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Impairment of neurovascular coupling in type 1 diabetes mellitus in rats is linked to PKC modulation of BK(Ca) and Kir channels.
American journal of physiology. Heart and circulatory physiology 20120315
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Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats.
American journal of physiology. Heart and circulatory physiology 20120301
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The LRRC26 protein selectively alters the efficacy of BK channel activators.
Molecular pharmacology 20120101
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Microglial Ca(2+)-activated K(+) channels are possible molecular targets for the analgesic effects of S-ketamine on neuropathic pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20111130
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Large conductance Ca2+ -activated K+ channel activation with NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle.
European journal of pharmacology 20111116
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Closure of multiple types of K+ channels is necessary to induce changes in renal vascular resistance in vivo in rats.
Pflugers Archiv : European journal of physiology 20111101
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CRH acts on CRH-R1 and -R2 to differentially modulate the expression of large-conductance calcium-activated potassium channels in human pregnant myometrium.
Endocrinology 20111101
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Effects of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients.
BJU international 20110801
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Functional and molecular characterization of maxi K+ -channels (BK(Ca)) in buffalo myometrium.
Animal reproduction science 20110701
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Phasic activity of urinary bladder smooth muscle in the streptozotocin-induced diabetic rat: effect of potassium channel modulators.
European journal of pharmacology 20110625
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The mitochondrial Ca(2+)-activated K(+) channel contributes to cardioprotection by limb remote ischemic preconditioning in rat.
Life sciences 20110606
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High glucose alters apoptosis and proliferation in HEK293 cells by inhibition of cloned BK Ca channel.
Journal of cellular physiology 20110601
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Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats.
Neuroscience letters 20110415
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Participation of BKCa2+ and KATP potassium ion channels in the contractility of human term pregnant myometrium in in vitro conditions.
The journal of obstetrics and gynaecology research 20110301
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Mitochondrial BKCa channels contribute to protection of cardiomyocytes isolated from chronically hypoxic rats.
American journal of physiology. Heart and circulatory physiology 20110201
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Role of large-conductance Ca²+-activated K+ channels in adenosine A₁ receptor-mediated pharmacological postconditioning in H9c2 cells.
Canadian journal of physiology and pharmacology 20110101
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BMS-191011, an opener of large-conductance Ca2+-activated potassium channels, dilates rat retinal arterioles in vivo.
Biological & pharmaceutical bulletin 20110101
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Cytoprotective action of the potassium channel opener NS1619 under conditions of disrupted calcium homeostasis.
Pharmacological reports : PR 20110101
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N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors.
Bioorganic & medicinal chemistry letters 20101215
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Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
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Inhibition of trigeminovascular dural nociceptive afferents by Ca(2+)-activated K(+) (MaxiK/BK(Ca)) channel opening.
Pain 20101001
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Antecedent ethanol attenuates cerebral ischemia/reperfusion-induced leukocyte-endothelial adhesive interactions and delayed neuronal death: role of large conductance, Ca2+-activated K+ channels.
Microcirculation (New York, N.Y. : 1994) 20100801
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KCa channels as therapeutic targets in episodic ataxia type-2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100526
-
Experimental diabetes mellitus down-regulates large-conductance Ca2+-activated K+ channels in cerebral artery smooth muscle and alters functional conductance.
Current neurovascular research 20100501
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Mitochondrial matrix K+ flux independent of large-conductance Ca2+-activated K+ channel opening.
American journal of physiology. Cell physiology 20100301
-
Arterial stiffness is regulated by nitric oxide and endothelium-derived hyperpolarizing factor during changes in blood flow in humans.
Hypertension (Dallas, Tex. : 1979) 20100301
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Expression of Ca2+ -activated K+ channels in human dermal fibroblasts and their roles in apoptosis.
Skin pharmacology and physiology 20100101
-
Activation of endothelial BKCa channels causes pulmonary vasodilation.
Vascular pharmacology 20100101
-
Large conductance calcium-activated potassium channels (BKCa) modulate trigeminovascular nociceptive transmission.
Cephalalgia : an international journal of headache 20091201
-
Impaired function of coronary BK(Ca) channels in metabolic syndrome.
American journal of physiology. Heart and circulatory physiology 20091101
-
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nature chemical biology 20091001
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Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model.
Cancer biology & therapy 20091001
-
Mechanism of differential cardiovascular response to propofol in Dahl salt-sensitive, Brown Norway, and chromosome 13-substituted consomic rat strains: role of large conductance Ca2+ and voltage-activated potassium channels.
The Journal of pharmacology and experimental therapeutics 20090901
-
Immediate neuronal preconditioning by NS1619.
Brain research 20090818
-
Activation of the BK(Ca) channel increases outflow facility and decreases trabecular meshwork cell volume.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090801
-
Plasticity and emerging role of BKCa channels in nociceptive control in neuropathic pain.
Journal of neurochemistry 20090701
-
Novel oxime and oxime ether derivatives of 12,14-dichlorodehydroabietic acid: design, synthesis, and BK channel-opening activity.
Bioorganic & medicinal chemistry letters 20081215
-
1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII.
European journal of medicinal chemistry 20081101
-
Restoration of calcium influx corrects membrane hyperexcitability in injured rat dorsal root ganglion neurons.
Anesthesia and analgesia 20080901
-
Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers.
Journal of medicinal chemistry 20080828
-
BK channel openers inhibit ROS production of isolated rat brain mitochondria.
Experimental neurology 20080801
-
Calcium-activated potassium channels contribute to human skeletal muscle microvascular endothelial dysfunction related to cardiopulmonary bypass.
Surgery 20080801
-
New amido derivatives as potential BKCa potassium channel activators. XI.
European journal of medicinal chemistry 20080401
-
The regulation of mitochondrial respiration by opening of mKCa channels is age-dependent.
European journal of pharmacology 20080114
-
Mitochondrial big conductance KCa channel and cardioprotection in infant rabbit heart.
Journal of cardiovascular pharmacology 20071101
-
The role of potassium ion channels in cough and other reflexes of the airways.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071101
-
The mitochondrial Ca2+-activated K+ channel activator, NS 1619 inhibits L-type Ca2+ channels in rat ventricular myocytes.
Biochemical and biophysical research communications 20071012
-
Reverse electron flow-induced ROS production is attenuated by activation of mitochondrial Ca2+-sensitive K+ channels.
American journal of physiology. Heart and circulatory physiology 20070901
-
Stimulation of Ca2+-gated Cl- currents by the calcium-dependent K+ channel modulators NS1619 [1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one] and isopimaric acid.
The Journal of pharmacology and experimental therapeutics 20070601
-
Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow.
The Journal of pharmacology and experimental therapeutics 20070501
-
Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels.
Naunyn-Schmiedeberg's archives of pharmacology 20070301
-
Pharmacological and physiological stimuli do not promote Ca(2+)-sensitive K+ channel activity in isolated heart mitochondria.
Cardiovascular research 20070301
-
3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR.
Journal of medicinal chemistry 20070208
-
The mitochondrial K(ATP) channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070201
-
[Effect of activation of mitochondrial ATP sensitive potassium channel and calcium activated potassium channel on the permeability transition of mitochondria from both normal and ischemic rat brain].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070201
-
Renovascular BK(Ca) channels are not activated in vivo under resting conditions and during agonist stimulation.
American journal of physiology. Regulatory, integrative and comparative physiology 20070101
-
Modulation by homocysteine of the iberiotoxin-sensitive, Ca2+ -activated K+ channels of porcine coronary artery smooth muscle cells.
European journal of pharmacology 20060928
-
Antiangiogenic effect of rosiglitazone is mediated via peroxisome proliferator-activated receptor gamma-activated maxi-K channel opening in human umbilical vein endothelial cells.
The Journal of biological chemistry 20060512
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
Cardiac mitochondrial preconditioning by Big Ca2+-sensitive K+ channel opening requires superoxide radical generation.
American journal of physiology. Heart and circulatory physiology 20060101
-
Heat shock protein modulation of KATP and KCa channel cerebrovasodilation after brain injury.
American journal of physiology. Heart and circulatory physiology 20050901
-
Doxapram stimulates the carotid body via a different mechanism than hypoxic chemotransduction.
Respiratory physiology & neurobiology 20050512
-
Influence of diabetes mellitus, hypercholesterolemia, and their combination on EDHF-mediated responses in mice.
Journal of cardiovascular pharmacology 20050501
-
The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues.
Journal of pharmacological sciences 20050501
-
Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning.
The Journal of pharmacology and experimental therapeutics 20050201
-
Mitochondrial Ca2+-activated K+ channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A.
Circulation 20050118
-
Nitric oxide stimulates a large-conductance Ca-activated K+ channel in human skin fibroblasts through protein kinase G pathway.
Skin pharmacology and physiology 20050101
-
Description and role in proliferation of iberiotoxin-sensitive currents in different human mammary epithelial normal and cancerous cells.
Biochimica et biophysica acta 20041215
-
Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice.
American journal of physiology. Heart and circulatory physiology 20041101
-
Cannabinoid receptor agonists inhibit sensory nerve activation in guinea pig airways.
American journal of respiratory and critical care medicine 20041101
-
Important role of superoxide dismutase in EDHF-mediated responses of human mesenteric arteries.
Journal of cardiovascular pharmacology 20041101
-
A novel mechanism of regulation of cardiac contractility by mitochondrial functional state.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801
-
Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle.
Naunyn-Schmiedeberg's archives of pharmacology 20040501
-
Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive K+ channels, and sodium nitroprusside and dibutyryl-cGMP.
European journal of pharmacology 20040405
-
Cilostazol enhances casein kinase 2 phosphorylation and suppresses tumor necrosis factor-alpha-induced increased phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and apoptotic cell death in SK-N-SH cells.
The Journal of pharmacology and experimental therapeutics 20040101
-
In vivo properties of potassium channels in cerebral blood vessels during diabetes mellitus.
Microcirculation (New York, N.Y. : 1994) 20040101
-
Cerebrovascular vasodilation to extraluminal acidosis occurs via combined activation of ATP-sensitive and Ca2+-activated potassium channels.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20031001
-
Natural modulators of large-conductance calcium-activated potassium channels.
Planta medica 20031001
-
Functional analysis of large conductance Ca2(+)-activated K(+) channels: ion flux studies by atomic absorption spectrometry.
Assay and drug development technologies 20031001
-
Cilostazol prevents tumor necrosis factor-alpha-induced cell death by suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and activation of Akt/cyclic AMP response element-binding protein phosphorylation.
The Journal of pharmacology and experimental therapeutics 20030901
-
The K+ channel openers diazoxide and NS1619 induce depolarization of mitochondria and have differential effects on cell Ca2+ in CD34+ cell line KG-1a.
Experimental hematology 20030901
-
Differential effects of pulsatile versus steady flow on coronary endothelial membrane potential.
American journal of physiology. Heart and circulatory physiology 20030701
-
Differential role of PTK and ERK MAPK in superoxide impairment of K(ATP) and K(Ca) channel cerebrovasodilation.
American journal of physiology. Regulatory, integrative and comparative physiology 20030701
-
Large-conductance K+ channel openers NS1619 and NS004 as inhibitors of mitochondrial function in glioma cells.
Biochemical pharmacology 20030601
-
BK channel openers inhibit migration of human glioma cells.
Pflugers Archiv : European journal of physiology 20030501
-
Coronary myogenic constriction antagonizes EDHF-mediated dilation: role of KCa channels.
Hypertension (Dallas, Tex. : 1979) 20030401
-
Doxapram stimulates carotid body with different mechanisms from hypoxic chemotransduction.
Advances in experimental medicine and biology 20030101
-
Modulation of action potential firing by iberiotoxin and NS1619 in rat dorsal root ganglion neurons.
Neuroscience 20030101
-
Prolonged activation of Ca2+-activated K+ current contributes to the long-lasting refractory period of Aplysia bag cell neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20021201
-
Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane.
Science (New York, N.Y.) 20021101
-
[BK channels play an important role as a negative feedback mechanism in the regulation of spontaneous rhythmic contraction of urinary bladder smooth muscles].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101
-
Protein tyrosine kinase and mitogen-activated protein kinase activation contribute to K(ATP) and K(ca) channel impairment after brain injury.
Brain research 20020712
-
4,5-diphenyltriazol-3-ones: openers of large-conductance Ca(2+)-activated potassium (maxi-K) channels.
Journal of medicinal chemistry 20020704
-
Enhancement of contraction of rat mesenteric artery by acteoside: role of endothelial nitric oxide.
Journal of natural products 20020701
-
Potassium channels and human corporeal smooth muscle cell tone: further evidence of the physiological relevance of the Maxi-K channel subtype to the regulation of human corporeal smooth muscle tone in vitro.
The Journal of urology 20020601
-
Regulation of blood-brain tumor barrier permeability by calcium-activated potassium channels.
The Journal of pharmacology and experimental therapeutics 20020601
-
14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries.
Circulation research 20020517
-
Vascular smooth muscle cell membrane depolarization after NOS inhibition hypertension.
American journal of physiology. Heart and circulatory physiology 20020501
-
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
-
[Changes in the post-ischemic glutaminic vascular reactions in newborn swine].
Ideggyogyaszati szemle 20020120
-
BK channel activity determines the extent of cell degeneration after oxygen and glucose deprivation: a study in organotypical hippocampal slice cultures.
Neuroscience 20020101
-
Human myofibroblastic hepatic stellate cells express Ca(2+)-activated K(+) channels that modulate the effects of endothelin-1 and nitric oxide.
Journal of hepatology 20011201
-
Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle.
Acta physiologica Scandinavica 20011101
-
New 5-substituted-1-(2-hydroxybenzoyl)-benzotriazoles, potassium channel activators. IV.
Farmaco (Societa chimica italiana : 1989) 20011101
-
Endothelin-Induced cyclooxygenase-dependent superoxide generation contributes to K+ channel functional impairment after brain injury.
Journal of neurotrauma 20011001
-
Vasopressin induced cyclooxygenase dependent superoxide generation contributes to K(+) channel function impairment after brain injury.
Brain research 20010810
-
Vasopressin-induced protein kinase C-dependent superoxide generation contributes to atp-sensitive potassium channel but not calcium-sensitive potassium channel function impairment after brain injury.
Stroke 20010601
-
Influence of Ca(2+)-activated K(+) channels on rat renal arteriolar responses to depolarizing agonists.
American journal of physiology. Renal physiology 20010401
-
Relaxant effects of 17-beta-estradiol in cerebral arteries through Ca(2+) entry inhibition.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010401
-
Modulation of recombinant small-conductance Ca(2+)-activated K(+) channels by the muscle relaxant chlorzoxazone and structurally related compounds.
The Journal of pharmacology and experimental therapeutics 20010301
-
A common mechanism for cystic fibrosis transmembrane conductance regulator protein activation by genistein and benzimidazolone analogs.
The Journal of pharmacology and experimental therapeutics 20010201
-
BK channel activation by NS-1619 is partially mediated by intracellular Ca2+ release in smooth muscle cells of porcine coronary artery.
British journal of pharmacology 20010201
