15641-58-4 | 2,2,3,3-Tetramethylcyclopropanecarboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
10g	95%	in stock	$14.00	$10.00
25g	95%	in stock	$25.00	$18.00
100g	95%	in stock	$54.00	$38.00
500g	95%	in stock	$249.00	$175.00

Description

• Catalog Number: AA78485
• Chemical Name: 2,2,3,3-Tetramethylcyclopropanecarboxylic acid
• CAS Number: 15641-58-4
• Molecular Formula: C8H14O2
• Molecular Weight: 142.1956
• MDL Number: MFCD00011538
• SMILES: OC(=O)C1C(C1(C)C)(C)C

Computed Properties

• Complexity: 166
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.9

Literature

• Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.

  Disease models & mechanisms 20120301

• Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.

  Epilepsy research 20120201

• Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.

  Journal of medicinal chemistry 20090423

• Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives.

  Biochemical pharmacology 20050515

• Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.

  Journal of medicinal chemistry 20040812