1576-37-0 | N-Benzyl-p-toluenesulfonamide

Packsize	Purity	Availability	Price	Discounted Price
50mg	98%	in stock	$6.00	$4.00
250mg	98%	in stock	$9.00	$6.00
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$36.00	$25.00
100g	98%	in stock	$401.00	$281.00

Description

• Catalog Number: AA79555
• Chemical Name: N-Benzyl-p-toluenesulfonamide
• CAS Number: 1576-37-0
• Molecular Formula: C14H15NO2S
• Molecular Weight: 261.3394
• MDL Number: MFCD00159328
• SMILES: Cc1ccc(cc1)S(=O)(=O)NCc1ccccc1
• NSC Number: 37123

Computed Properties

• Complexity: 333
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 2.7

Literature

• Paying the piper: the cost of Ca2+ pumping during the mating call of toadfish.

  The Journal of physiology 20111115

• Patterned femtosecond-laser ablation of Xenopus laevis melanocytes for studies of cell migration, wound repair, and developmental processes.

  Biomedical optics express 20110801

• Disrupted membrane structure and intracellular Ca²⁺ signaling in adult skeletal muscle with acute knockdown of Bin1.

  PloS one 20110101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• N-Benzyl-N-ethyl-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20101001

• Second harmonic generation microscopy probes different states of motor protein interaction in myofibrils.

  Biophysical journal 20100922

• Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis.

  Aging 20100801

• Is the cross-bridge stiffness proportional to tension during muscle fiber activation?

  Biophysical journal 20100602

• Skeletal muscle excitation-contraction coupling is independent of a conserved heptad repeat motif in the C-terminus of the DHPRbeta(1a) subunit.

  Cell calcium 20100601

• Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells.

  American journal of physiology. Endocrinology and metabolism 20100501

• ATP consumption by sarcoplasmic reticulum Ca2+ pumps accounts for 50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle.

  American journal of physiology. Cell physiology 20100301

• Loss of Smyhc1 or Hsp90alpha1 function results in different effects on myofibril organization in skeletal muscles of zebrafish embryos.

  PloS one 20100101

• Glycolysis in contracting rat skeletal muscle is controlled by factors related to energy state.

  The Biochemical journal 20090513

• A myosin II ATPase inhibitor reduces force production, glucose transport, and phosphorylation of AMPK and TBC1D1 in electrically stimulated rat skeletal muscle.

  American journal of physiology. Endocrinology and metabolism 20090501

• The effect of myofilament compliance on kinetics of force generation by myosin motors in muscle.

  Biophysical journal 20090121

• Defective glycinergic synaptic transmission in zebrafish motility mutants.

  Frontiers in molecular neuroscience 20090101

• The energetic cost of activation in mouse fast-twitch muscle is the same whether measured using reduced filament overlap or N-benzyl-p-toluenesulphonamide.

  Acta physiologica (Oxford, England) 20080801

• Causes of excitation-induced muscle cell damage in isometric contractions: mechanical stress or calcium overload?

  American journal of physiology. Regulatory, integrative and comparative physiology 20070601

• Energy conservation attenuates the loss of skeletal muscle excitability during intense contractions.

  American journal of physiology. Endocrinology and metabolism 20070301

• Mechanical load plays little role in contraction-mediated glucose transport in mouse skeletal muscle.

  The Journal of physiology 20070301

• Voltage-dependent calcium influx mediates maturation of myofibril arrangement in ascidian larval muscle.

  Developmental biology 20070115

• Effects of BTS (N-benzyl-p-toluene sulphonamide), an inhibitor for myosin-actin interaction, on myofibrillogenesis in skeletal muscle cells in culture.

  Zoological science 20061101

• Cross bridges account for only 20% of total ATP consumption during submaximal isometric contraction in mouse fast-twitch skeletal muscle.

  American journal of physiology. Cell physiology 20060701

• Measurement of activation energy and oxidative phosphorylation onset kinetics in isolated muscle fibers in the absence of cross-bridge cycling.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060601

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• The effects of the myosin-II inhibitor N-benzyl-p-toluene sulphonamide on fatigue in mouse single intact toe muscle fibres.

  Acta physiologica (Oxford, England) 20060101

• N-Benzyl-p-toluene sulphonamide allows the recording of trains of intracellular action potentials from nerve-stimulated intact fast-twitch skeletal muscle of the rat.

  Experimental physiology 20051101

• Inhibition of cross-bridge formation has no effect on contraction-associated phosphorylation of p38 MAPK in mouse skeletal muscle.

  American journal of physiology. Cell physiology 20050401

• Cardiac troponin C (TnC) and a site I skeletal TnC mutant alter Ca2+ versus crossbridge contribution to force in rabbit skeletal fibres.

  The Journal of physiology 20050201

• Effects of a myosin-II inhibitor (N-benzyl-p-toluene sulphonamide, BTS) on contractile characteristics of intact fast-twitch mammalian muscle fibres.

  Journal of muscle research and cell motility 20050101

• The action potential-evoked sarcoplasmic reticulum calcium release is impaired in mdx mouse muscle fibres.

  The Journal of physiology 20040515

• Cross-bridge blocker BTS permits direct measurement of SR Ca2+ pump ATP utilization in toadfish swimbladder muscle fibers.

  American journal of physiology. Cell physiology 20031001

• Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide.

  Biochemistry 20030527

• Skeletal muscle myosin cross-bridge cycling is necessary for myofibrillogenesis.

  Cell motility and the cytoskeleton 20030501

• A small-molecule inhibitor of skeletal muscle myosin II.

  Nature cell biology 20020101