15826-37-6 | Cromolyn disodium salt hydrate

Packsize	Purity	Availability	Price	Discounted Price
10mg	97%	in stock	$6.00	$4.00
50mg	97%	in stock	$8.00	$6.00
1g	97%	in stock	$16.00	$11.00
5g	97%	in stock	$53.00	$37.00
10g	97%	in stock	$100.00	$70.00
25g	97%	in stock	$181.00	$127.00

Description

• Catalog Number: AB79085
• Chemical Name: Cromolyn disodium salt hydrate
• CAS Number: 15826-37-6
• Molecular Formula: C23H14Na2O11
• Molecular Weight: 512.3302
• MDL Number: MFCD00057744
• SMILES: OC(COc1cccc2c1c(=O)cc(o2)C(=O)[O-])COc1cccc2c1c(=O)cc(o2)C(=O)[O-].[Na+].[Na+]

Computed Properties

• Complexity: 824
• Covalently-Bonded Unit Count: 3
• Heavy Atom Count: 36
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 6

Literature

• Cromolyn chitosan nanoparticles as a novel protective approach for colorectal cancer.

  Chemico-biological interactions 20170925

• Inhibitory effect of putranjivain A on allergic inflammation through suppression of mast cell activation.

  Toxicology and applied pharmacology 20140201

• Cromolyn sodium for insulin-induced lipoatrophy: old drug, new use.

  Diabetes care 20131201

• Naproxen and cromolyn as new glycogen synthase kinase 3β inhibitors for amelioration of diabetes and obesity: an investigation by docking simulation and subsequent in vitro/in vivo biochemical evaluation.

  Journal of biochemical and molecular toxicology 20130901

• Molecularly imprinted polymers for histamine recognition in aqueous environment.

  Amino acids 20121101

• Inhibiting tryptase after ischemia limits small intestinal ischemia-reperfusion injury through protease-activated receptor 2 in rats.

  The journal of trauma and acute care surgery 20121101

• Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice.

  Laboratory investigation; a journal of technical methods and pathology 20121001

• Mast cells activation contribute to small intestinal ischemia reperfusion induced acute lung injury in rats.

  Injury 20120801

• Pseudobronchiectasis after pertussis and mycoplasma infection.

  American journal of respiratory and critical care medicine 20120801

• Efficacy of topical cromolyn sodium 4% on pruritus in uremic nephrogenic patients: a randomized double-blind study in 60 patients.

  International journal of clinical pharmacology and therapeutics 20120701

• Cromolyn sodium for the prevention of chronic lung disease in preterm infants.

  The Cochrane database of systematic reviews 20120613

• Mast-cell-releasing tryptase triggers acute lung injury induced by small intestinal ischemia-reperfusion by activating PAR-2 in rats.

  Inflammation 20120601

• Diagnostics and new developments in the treatment of ocular allergies.

  Current allergy and asthma reports 20120601

• In vivo hydroquinone exposure causes tracheal hyperresponsiveness due to TNF secretion by epithelial cells.

  Toxicology letters 20120520

• Humoral regulation of heart rate during digestion in pythons (Python molurus and Python regius).

  American journal of physiology. Regulatory, integrative and comparative physiology 20120515

• Exhaled carbon monoxide levels in preschool-age children with episodic asthma.

  Pediatrics international : official journal of the Japan Pediatric Society 20120401

• SCF and TLR4 ligand cooperate to augment the tumor-promoting potential of mast cells.

  Cancer immunology, immunotherapy : CII 20120301

• Mast cell inhibition improves pulmonary vascular remodeling in pulmonary hypertension.

  Chest 20120301

• Modification of disodium cromoglycate passage across lung epithelium in vitro via incorporation into polymeric microparticles.

  The AAPS journal 20120301

• Liposomes: a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitis.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20120201

• Pharmacotherapy of rhinitis and rhinosinusitis.

  Facial plastic surgery clinics of North America 20120201

• Characterization of a model of tracheal plasma extravasation in passively sensitized rats using anti-allergic and anti-inflammatory drugs by oral and intratracheal route.

  Pulmonary pharmacology & therapeutics 20120201

• In vivo antitumor effect of cromolyn in PEGylated liposomes for pancreatic cancer.

  Journal of controlled release : official journal of the Controlled Release Society 20120130

• Refractory symptoms successfully treated with leukotriene inhibition in a child with systemic mastocytosis.

  Pediatric dermatology 20120101

• [Treatment of eye allergies].

  Duodecim; laaketieteellinen aikakauskirja 20120101

• Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans.

  PloS one 20120101

• Anti-inflammatory gallic Acid and wedelolactone are G protein-coupled receptor-35 agonists.

  Pharmacology 20120101

• Salivary cortisol monitoring: determination of reference values in healthy children and application in asthmatic children.

  Allergy and asthma proceedings 20120101

• Topical use of sodium cromoglicate (cromolyn sodium) to treat atopic dermatitis and other skin allergies.

  International journal of pharmaceutical compounding 20120101

• Cerebral mast cells mediate blood-brain barrier disruption in acute experimental ischemic stroke through perivascular gelatinase activation.

  Stroke 20111201

• Development and validation of a nighttime sleep diary in asthmatic children.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20111101

• Mast cell stabilization: novel medication for obesity and diabetes.

  Diabetes/metabolism research and reviews 20111101

• A double-masked study to compare the efficacy and safety of topical cromolyn for the treatment of allergic conjunctivitis.

  Journal of the Formosan Medical Association = Taiwan yi zhi 20111101

• Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists.

  Journal of medicinal chemistry 20111027

• Sensory nerve induced inflammation contributes to heterotopic ossification.

  Journal of cellular biochemistry 20111001

• Mast cell function and death in Trypanosoma cruzi infection.

  The American journal of pathology 20111001

• Noncovalent polymerization of mesogens crystallizes lysozyme: correlation between nonamphiphilic lyotropic liquid crystal phase and protein crystal formation.

  Langmuir : the ACS journal of surfaces and colloids 20110906

• The significance of chloride in the inhibitory action of disodium cromoglycate on immunologically-stimulated rat peritoneal mast cells.

  Biochimica et biophysica acta 20110901

• Effects of disodium cromoglycate on cationic exchange of deoxygenated sickle cells.

  European journal of pharmacology 20110831

• Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.

  Pain 20110801

• The role of decongestants, cromolyn, guafenesin, saline washes, capsaicin, leukotriene antagonists, and other treatments on rhinitis.

  Immunology and allergy clinics of North America 20110801

• Chrysin suppresses mast cell-mediated allergic inflammation: involvement of calcium, caspase-1 and nuclear factor-κB.

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• 1H and 13C NMR studies of glycine in anisotropic media: double-quantum transitions and the effects of chiral interactions.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20110701

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• Synthesis of novel mast cell-stabilising and anti-allergic 1,2,3,4-tetrahydro-1-naphthalenols and related compounds.

  European journal of medicinal chemistry 20110501

• Sodium cromolyn reduces expression of CTGF, ADAMTS1, and TIMP3 and modulates post-injury patellar tendon morphology.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20110501

• Effect of aminoguanidine on the conjunctival histamine and nitrite levels in experimental conjunctivitis.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110401

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  International journal of pharmaceutics 20110227

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  International journal of dermatology 20110201

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  Phytomedicine : international journal of phytotherapy and phytopharmacology 20110115

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  Pediatric dermatology 20110101

• Sodium cromoglycate and eformoterol attenuate sensitivity and reactivity to inhaled mannitol in subjects with bronchiectasis.

  Respirology (Carlton, Vic.) 20110101

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  Expert opinion on drug delivery 20110101

• Ameliorative potential of sodium cromoglycate and diethyldithiocarbamic acid in restraint stress-induced behavioral alterations in rats.

  Pharmacological reports : PR 20110101

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  Respiratory research 20110101

• Disodium cromoglycate attenuates hypoxia induced enlargement of end-expiratory lung volume in rats.

  Physiological research 20110101

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  The Biochemical journal 20101215

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  Magnetic resonance in chemistry : MRC 20101101

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  Bioorganic & medicinal chemistry letters 20101101

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  Acta dermato-venereologica 20101101

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  Medicine and science in sports and exercise 20101001

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  Microcirculation (New York, N.Y. : 1994) 20101001

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  European journal of clinical pharmacology 20100901

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  Arteriosclerosis, thrombosis, and vascular biology 20100901

• Noncovalent polymerization and assembly in water promoted by thermodynamic incompatibility.

  The journal of physical chemistry. B 20100819

• Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 1. Albuterol sulfate and disodium cromoglycate.

  Journal of pharmaceutical sciences 20100801

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  Medizinische Klinik (Munich, Germany : 1983) 20100801

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  World journal of gastroenterology 20100721

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  Journal of immunology (Baltimore, Md. : 1950) 20100701

• Interactive medical case. A rash hypothesis.

  The New England journal of medicine 20100617

• Treatment of allergic rhinitis.

  American family physician 20100615

• Asthma in pregnancy: pathophysiology, diagnosis and management.

  Obstetrics and gynecology clinics of North America 20100601

• Effect of oral cromolyn sodium on CKD-associated pruritus and serum tryptase level: a double-blind placebo-controlled study.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501

• Exercise-induced wheeze: Fraction of exhaled nitric oxide-directed management.

  Respirology (Carlton, Vic.) 20100501

• Sodium cromoglycate alone and in combination with montelukast on the airway response to mannitol in asthmatic subjects.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20100501

• Effect of dodecylmaltoside (DDM) on uptake of BCS III compounds, tiludronate and cromolyn, in Caco-2 cells and rat intestine model.

  Drug delivery 20100401

• Shared treatment decision making improves adherence and outcomes in poorly controlled asthma.

  American journal of respiratory and critical care medicine 20100315

• Topical sodium cromoglicate relieves allergen- and histamine-induced dermal pruritus.

  The British journal of dermatology 20100301

• Early weaning stress impairs development of mucosal barrier function in the porcine intestine.

  American journal of physiology. Gastrointestinal and liver physiology 20100301

• Skin thickness in children treated with daily or periodical inhaled budesonide for mild persistent asthma. The Helsinki early intervention childhood asthma study.

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• Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts.

  The Journal of clinical investigation 20100104

• Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators involved.

  Toxicon : official journal of the International Society on Toxinology 20100101

• Synthesis and evaluation of dimeric 1,2,3,4-tetrahydro-naphthalenylamine and indan-1-ylamine derivatives with mast cell-stabilising and anti-allergic activity.

  European journal of medicinal chemistry 20100101

• Tramadol-induced seizurogenic effect: a possible role of opioid-dependent histamine H1 receptor activation-linked mechanism.

  Naunyn-Schmiedeberg's archives of pharmacology 20100101

• Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study.

  European journal of ophthalmology 20100101

• Prevention of mast cell degranulation by disodium cromoglycate delayed the regression of hypoxic pulmonary hypertension in rats.

  Respiration; international review of thoracic diseases 20100101

• Localized cold urticaria to the face in a pediatric patient: a case report and literature review.

  Pediatric dermatology 20100101

• Anti-allergic drugs and the Annexin-A1 system.

  Pharmacological reports : PR 20100101

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  Duodecim; laaketieteellinen aikakauskirja 20100101

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  The Cochrane database of systematic reviews 20100101

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  European journal of dermatology : EJD 20100101

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  Ceskoslovenska fysiologie 20100101

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• Diastereoisomers of 2-benzyl-2, 3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol: potential anti-inflammatory agents.

  Bioorganic & medicinal chemistry letters 20091015

• The effect of asthma therapeutics on signalling and transcriptional regulation of airway smooth muscle function.

  Pulmonary pharmacology & therapeutics 20091001

• Role of mast cells and protease-activated receptor-2 in cyclooxygenase-2 expression in urothelial cells.

  American journal of physiology. Regulatory, integrative and comparative physiology 20091001

• Mast cells are early responders after hypoxia-ischemia in immature rat brain.

  Stroke 20090901

• Development of a rapid and automatic optosensor for the determination of cromolyn in biological samples.

  Talanta 20090815

• The effects of disodium cromoglycate on enhanced adherence of Haemophilus influenzae to A549 cells infected with respiratory syncytial virus.

  Pediatric research 20090801

• Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

  Nature medicine 20090801

• Cyclosporine A eye drops inhibit the early-phase reaction in a type-I allergic conjunctivitis model in mice.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090801

• Mast cell degranulation--a mechanism for the anti-arrhythmic effect of endothelin-1?

  British journal of pharmacology 20090701

• Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1.

  Biochemical pharmacology 20090615

• Comparison of efficacy of bromfenac sodium 0.1% ophthalmic solution and fluorometholone 0.02% ophthalmic suspension for the treatment of allergic conjunctivitis.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090601

• The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats.

  European journal of pain (London, England) 20090501

• Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae).

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20090301

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  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090301

• Up-regulation of S100P expression by non-steroidal anti-inflammatory drugs and its role in anti-tumorigenic effects.

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  Nihon Jibiinkoka Gakkai kaiho 20090201

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  Pharmacology 20090101

• Synthesis and evaluation of 4-amino-3,4-dihydro-2H-naphthalen-1-one derivatives as mast cell stabilising and anti-inflammatory compounds.

  European journal of medicinal chemistry 20081201

• Chemical and physical compatibility of levalbuterol inhalation solution concentrate mixed with budesonide, ipratropium bromide, cromolyn sodium, or acetylcysteine sodium.

  Respiratory care 20081201

• Inhaled sodium cromoglycate for asthma in children.

  The Cochrane database of systematic reviews 20081008

• Ophthalmologic findings in children with asthma receiving inhaled budesonide.

  The Journal of allergy and clinical immunology 20081001

• Compatibility and aerosol characteristics of formoterol fumarate mixed with other nebulizing solutions.

  The Annals of pharmacotherapy 20081001

• Influence of cromolyn sodium and compound 48/80 administered prior to and after reperfusion on the third day's survival rate in a rat intestinal ischemia model.

  Chinese medical journal 20080920

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  The Veterinary record 20080906

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  Biomedical chromatography : BMC 20080901

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  Yao xue xue bao = Acta pharmaceutica Sinica 20080901

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  Archives of disease in childhood. Fetal and neonatal edition 20080701

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  British journal of pharmacology 20080701

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  International journal of pharmaceutics 20080624

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  International journal of pharmaceutics 20080605

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  International journal of pharmaceutics 20080605

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  Annual review of immunology 20080101

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  International archives of allergy and immunology 20080101

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  Respiration; international review of thoracic diseases 20080101

• Prevention of exercise-induced asthma by a fixed combination of disodium cromoglycate plus reproterol compared with montelukast in young patients.

  Arzneimittel-Forschung 20080101

• Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the survival rates after intestinal ischemia reperfusion injury in rats.

  BMC gastroenterology 20080101

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  Allergy 20071201

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  Nihon rinsho. Japanese journal of clinical medicine 20071028

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  Nederlands tijdschrift voor geneeskunde 20071013

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  American journal of physiology. Gastrointestinal and liver physiology 20070801

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  International journal of colorectal disease 20070701

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• Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.

  European journal of pharmacology 20070601

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  Arthritis and rheumatism 20070601

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  Pediatrics international : official journal of the Japan Pediatric Society 20070601

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  Circulation 20070515

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  Circulation 20070515

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  Pediatric pulmonology 20070501

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  Reproduction (Cambridge, England) 20070501

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  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070401

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  British journal of anaesthesia 20070301

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  Lung 20070101

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  Journal of the National Cancer Institute 20061220

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  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20061201

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• A brief history of inhaled asthma therapy over the last fifty years.

  Primary care respiratory journal : journal of the General Practice Airways Group 20061201

• Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.

  European annals of allergy and clinical immunology 20061201

• Binding of anti-inflammatory drug cromolyn sodium to bovine serum albumin.

  International journal of biological macromolecules 20061115

• Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat.

  Journal of immunology (Baltimore, Md. : 1950) 20061115

• Clinical response of patients with sickle cell anemia to cromolyn sodium nasal spray.

  American journal of hematology 20061101

• [Enhancement of nonsteroidal, anti-inflammatory drugs and preventive effect of antihistamines and disodium cromoglycate on wheat allergy].

  Arerugi = [Allergy] 20061001

• Health economic impact of olopatadine compared to branded and generic sodium cromoglycate in the treatment of seasonal allergic conjunctivitis in the UK.

  Current medical research and opinion 20060901

• Cromolyn administration (to block mast cell degranulation) reduces necrosis of dystrophic muscle in mdx mice.

  Neurobiology of disease 20060801

• A late cutaneous response in actively sensitized rats: a new method for evaluating the efficacy of antiallergic drugs.

  Journal of pharmacological sciences 20060801

• Protective effects of nedocromil sodium and sodium cromoglycate on gastroduodenal ulcers: a comparative study in rats.

  Inflammopharmacology 20060801

• Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents.

  The American journal of pathology 20060701

• Lyotropic liquid crystal as a real-time detector of microbial immune complexes.

  Letters in applied microbiology 20060701

• Assessing the impact of asthma guideline implementation.

  Chest 20060701

• The interaction and compatibility between a soft contact lens and an ophthalmic drug.

  Eye & contact lens 20060701

• Cerebral mast cells regulate early ischemic brain swelling and neutrophil accumulation.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060501

• Exhaled carbon monoxide levels in school-age children with episodic asthma.

  Pediatric pulmonology 20060501

• Inhibition of mast cell PGD2 release protects against mannitol-induced airway narrowing.

  The European respiratory journal 20060501

• Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma.

  The Cochrane database of systematic reviews 20060419

• The effect of cromoglycate on time-dependent histamine and serotonin concentrations in stored blood products.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20060401

• Nociceptin-induced histamine release in the brain: comparison with compound 48/80- and substance P-induced amine secretions.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• The inhibitory effect of disodium cromoglycate on the growth of Chlamydophila (Chlamydia) pneumoniae in vitro.

  Biological & pharmaceutical bulletin 20060401

• Expression of urocortin in rat lung and its effect on pulmonary vascular permeability.

  The Journal of endocrinology 20060401

• Cromolyn sodium: a potential therapy for uremic pruritus?

  Hemodialysis international. International Symposium on Home Hemodialysis 20060401

• Inhibition of mast cell degranulation-induced drop of blood pressure with clemastine, cromolyn and compound 48/80 pretreatment.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• Effects of nebulized sodium cromoglycate on adult patients with severe refractory asthma.

  Respiratory medicine 20060301

• Mucosal eosinophilia and response to H1/H2 antagonist and cromolyn therapy in pediatric dyspepsia.

  Clinical pediatrics 20060301

• Anti-allergic properties of Mangifera indica L. extract (Vimang) and contribution of its glucosylxanthone mangiferin.

  The Journal of pharmacy and pharmacology 20060301

• Effectiveness of budesonide nebulising suspension compared to disodium cromoglycate in early childhood asthma.

  Current medical research and opinion 20060201

• Managing asthma in expectant mothers.

  Treatments in respiratory medicine 20060101

• Oral beta2-agonist use by preschool children with asthma in East and Central Harlem, New York.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20060101

• Mononuclear cell membranes: stabilization by reproterol and cromoglycate, destabilization by fenoterol and salbutamol.

  Arzneimittel-Forschung 20060101

• Effects of early intervention with inhaled sodium cromoglycate in childhood asthma.

  Lung 20060101

• Forskolin versus sodium cromoglycate for prevention of asthma attacks: a single-blinded clinical trial.

  The Journal of international medical research 20060101

• Disodium cromoglycate inhibits capsaicin-induced eosinophil infiltration of conjunctiva independent of mast cells.

  Japanese journal of ophthalmology 20060101

• A cross-sectional study of medication-related factors and caries experience in asthmatic children.

  Pediatric dentistry 20060101

• Nebulized drug admixtures: effect on aerosol characteristics and albuterol output.

  Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20060101

• Interaction of cromolyn sodium with human serum albumin: a fluorescence quenching study.

  Bioorganic & medicinal chemistry 20051215

• Sodium cromoglycate therapy in wheezing infants: preliminary evidence of beneficial outcome at early school age.

  Pediatrics international : official journal of the Japan Pediatric Society 20051201

• Eosinophilic esophagitis: a 10-year experience in 381 children.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20051201

• Asthma and other wheezing disorders in children.

  Clinical evidence 20051201

• Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma.

  International archives of allergy and immunology 20051101

• Involvement of mast cells in the development of fibrosis in rats with postmyocarditis dilated cardiomyopathy.

  Biological & pharmaceutical bulletin 20051101

• Salt effects on the phase behavior, structure, and rheology of chromonic liquid crystals.

  The journal of physical chemistry. B 20051020

• Effect of amino acids on the dispersion of disodium cromoglycate powders.

  Journal of pharmaceutical sciences 20051001

• [Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise].

  Arerugi = [Allergy] 20051001

• Role of gastric mast cells in the regulation of central TRH analog-induced hyperemia in rats.

  Peptides 20050901

• Efficacy, cost-effectiveness, and tolerability of mometasone furoate, levocabastine, and disodium cromoglycate nasal sprays in the treatment of seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050901

• Mast cell involvement in the adenosine mediated airway hyper-reactivity in a murine model of ovalbumin-induced lung inflammation.

  British journal of pharmacology 20050801

• The effect of water to ethanol feed ratio on physical properties and aerosolization behavior of spray dried cromolyn sodium particles.

  Journal of pharmaceutical sciences 20050501

• The challenge of mild persistent asthma.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050501

• [Hyper-IgE syndrome].

  Nihon rinsho. Japanese journal of clinical medicine 20050501

• Roger Altounyan and the discovery of cromolyn (sodium cromoglycate).

  The Journal of allergy and clinical immunology 20050401

• The discovery of cromolyn sodium and its effect on research and practice in allergy and immunology.

  The Journal of allergy and clinical immunology 20050401

• Cromolyn sodium: fitting an old friend into current asthma treatment.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20050301

• Predicting the clinical course of suspected acute viral upper respiratory tract infection in children.

  Family practice 20050201

• Asthma controller therapy during pregnancy.

  American journal of obstetrics and gynecology 20050201

• Efficacy and acceptability of a new topical skin lotion of sodium cromoglicate (Altoderm) in atopic dermatitis in children aged 2-12 years: a double-blind, randomized, placebo-controlled trial.

  The British journal of dermatology 20050201

• NAEPP expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update.

  The Journal of allergy and clinical immunology 20050101

• Effect of reproterol either alone or combined with disodium cromoglycate on airway responsiveness to methacholine.

  Pulmonary pharmacology & therapeutics 20050101

• [What is the treatment for atopic dermatitis flares in children?].

  Annales de dermatologie et de venereologie 20050101

• [Development of technology of sodium cromoglycate eye drops].

  Medicina (Kaunas, Lithuania) 20050101

• Lung deposition after electronically breath-controlled inhalation and manually triggered conventional inhalation in cystic fibrosis patients.

  Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20050101

• [Strategies for the prevention and treatment of allergies in children and adolescents].

  MMW Fortschritte der Medizin 20041209

• Prevention of adhesions by sodium chromoglycate, dexamethasone, saline and aprotinin after pelvic surgery.

  ANZ journal of surgery 20041201

• Oral absorption enhancement of cromolyn sodium through noncovalent complexation.

  Pharmaceutical research 20041201

• The effect of vehicle on physical properties and aerosolisation behaviour of disodium cromoglycate microparticles spray dried alone or with L-leucine.

  International journal of pharmaceutics 20041105

• Pharmacologic approaches to daytime and nighttime symptoms of allergic rhinitis.

  The Journal of allergy and clinical immunology 20041101

• Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women.

  American journal of obstetrics and gynecology 20041101

• The effect of montelukast versus usual care on health care resource utilization in children aged 2 to 5 years with asthma.

  Clinical therapeutics 20041101

• Induction of premature labor and delivery by allergic reaction and prevention by histamine H1 receptor antagonist.

  American journal of obstetrics and gynecology 20041001

• Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters.

  Circulation 20040921

• Intratracheal dosing with disodium cromoglycate inhibits late asthmatic response by attenuating eicosanoid production in guinea pigs.

  European journal of pharmacology 20040816

• Induced sputum in children with newly diagnosed mild asthma: the effect of 6 months of treatment with budesonide or disodium cromoglycate.

  Allergy 20040801

• Cough and angioedema from angiotensin-converting enzyme inhibitors: new insights into mechanisms and management.

  Current opinion in allergy and clinical immunology 20040801

• Prevention of bronchoconstriction in sensitized guinea pigs: efficacy of common prophylactic drugs.

  Respiratory physiology & neurobiology 20040720

• Tolerance induction to rofecoxib in a patient with Bartter's syndrome.

  Allergy 20040701

• Are inhaled corticosteroids safe and effective in infants with asthma-like symptoms?

  Pediatrics 20040701

• In vitro and in vivo inhibitory effects of disodium cromoglycate on influenza virus infection.

  Biological & pharmaceutical bulletin 20040601

• Asthma and other wheezing disorders in infants and children.

  Clinical evidence 20040601

• Disodium cromoglycate stabilizes mast cell degranulation while reducing the number of hemoglobin-induced microvascular leaks in rat mesentery.

  American journal of physiology. Heart and circulatory physiology 20040501

• Pemirolast potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats.

  Neuropharmacology 20040501

• Self-association of cromolyn sodium in aqueous solution characterized by nuclear magnetic resonance spectroscopy.

  Journal of pharmaceutical sciences 20040501

• Mast cells and reactive oxygen species in citric acid-induced airway constriction.

  Journal of applied physiology (Bethesda, Md. : 1985) 20040501

• Effect of disodium cromoglycate on mast cell-mediated immediate-type allergic reactions.

  Life sciences 20040423

• [Pediatric bronchial asthma. How reliable are the guidelines?].

  MMW Fortschritte der Medizin 20040422

• LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam.

  Phytochemistry 20040401

• Disodium cromoglycate suppresses the induction of cysteinyl leukotriene synthesis during granulocytic differentiation in HL-60 cells.

  Respiratory medicine 20040301

• Mast cells degranulation affects angiogenesis in the rat uterine cervix during pregnancy.

  Reproduction (Cambridge, England) 20040301

• Histamine and fluoxetine: common playground in the rat conjunctiva?

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301

• Twelve-month safety and efficacy of inhaled fluticasone propionate in children aged 1 to 3 years with recurrent wheezing.

  Pediatrics 20040201

• A method for determining whether hypotension caused by novel compounds in preclinical development results from histamine release.

  Journal of pharmacological and toxicological methods 20040101

• A simple pharmacokinetic method to evaluate the pulmonary dose in clinical practice--analyses of inhaled sodium cromoglycate.

  Respiratory medicine 20040101

• Treatment of allergic rhinitis during pregnancy.

  American journal of rhinology 20040101

• Inhaled cromones for prolonged non-specific cough in children.

  The Cochrane database of systematic reviews 20040101

• Does wearing a noseclip during inhalation improve lung deposition?

  Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20040101

• Acute asthma attack caused by ophthalmic application of antiallergic agents.

  Japanese journal of ophthalmology 20040101

• Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats?

  Journal of toxicology. Clinical toxicology 20040101

• Single-dose agents in the prevention of exercise-induced asthma: a descriptive review.

  Treatments in respiratory medicine 20040101

• [Lung functioning changes of asthmatic adults in treatment with cromolyn sodium and beclomethasone].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101

• Activation of mast cells by systemic hypoxia, but not by local hypoxia, mediates increased leukocyte-endothelial adherence in cremaster venules.

  Journal of applied physiology (Bethesda, Md. : 1985) 20031201

• Clinical course of acute infection of the upper respiratory tract in children: cohort study.

  BMJ (Clinical research ed.) 20031108

• Disodium cromoglycate prevents ileum hyperreactivity to histamine in Toxocara canis-infected guinea pigs.

  Pharmacological research 20031101

• No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis.

  Pediatric pulmonology 20031101

• Hyaluronidase inhibitors (sodium cromoglycate and sodium auro-thiomalate) reduce the local tissue damage and prolong the survival time of mice injected with Naja kaouthia and Calloselasma rhodostoma venoms.

  Toxicon : official journal of the International Society on Toxinology 20031101

• Mast cell inhibitor cromolyn increases blood clotting and hypoxia in murine breast cancer.

  International journal of cancer 20031020

• Norepinephrine-induced cardiac hypertrophy and fibrosis are not due to mast cell degranulation.

  Molecular and cellular biochemistry 20031001

• Cost-effective pharmacotherapy for inhalant allergic rhinitis.

  Otolaryngologic clinics of North America 20031001

• Salmeterol versus sodium cromoglycate for the protection of exercise induced asthma in children--a randomised cross-over study.

  European journal of medical research 20030929

• Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox.

  The Biochemical journal 20030901

• Effects of budesonide inhalation suspension compared with cromolyn sodium nebulizer solution on health status and caregiver quality of life in childhood asthma.

  Pediatrics 20030901

• Tricin from a malagasy connaraceous plant with potent antihistaminic activity.

  Journal of natural products 20030901

• Oral disodium cromoglycate and ketotifen for a patient with eosinophilic gastroenteritis, food allergy and protein-losing enteropathy.

  Asian Pacific journal of allergy and immunology 20030901

• No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis.

  Pediatric pulmonology 20030801

• The role of the mast cell in asthma.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030801

• Stress-induced interleukin-6 release in mice is mast cell-dependent and more pronounced in Apolipoprotein E knockout mice.

  Cardiovascular research 20030701

• Salmeterol resolves airway obstruction but does not possess anti-eosinophil efficacy in newly diagnosed asthma: a randomized, double-blind, parallel group biopsy study comparing the effects of salmeterol, fluticasone propionate, and disodium cromoglycate.

  The Journal of allergy and clinical immunology 20030701

• General strategy for the management of bronchial asthma in pregnancy.

  Respiratory medicine 20030701

• Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products.

  American journal of obstetrics and gynecology 20030601

• Antiallergic activity of ginseng and its ginsenosides.

  Planta medica 20030601

• Asthma and other wheezing disorders of childhood.

  Clinical evidence 20030601

• Development and validation of a sensitive liquid chromatographic-tandem mass spectrometric method for the determination of cromolyn sodium in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505

• Anti-inflammatory treatment for recurrent wheezing in the first five years of life.

  Pediatric pulmonology 20030401

• Effect of protease-activated receptors on guinea-pig ileum contraction in vitro.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401

• A combined analysis of two studies assessing the ocular comfort of antiallergy ophthalmic agents.

  Clinical therapeutics 20030401

• Treatment compliance, passive smoking, and asthma control: a three year cohort study.

  Archives of disease in childhood 20030301

• Adenosine monophosphate bronchial provocation and the actions of asthma therapy.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030301

• Salbutamol, beclomethasone or sodium chromoglycate suppress coughing induced by iv fentanyl.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20030301

• In-situ-micronization of disodium cromoglycate for pulmonary delivery.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030301

• The role of aspirin in vernal keratoconjunctivitis.

  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20030301

• The anti-allergic effects of a cromolyn sodium-chlorpheniramine combination compared to ketotifen in the conjunctival allergen challenge model.

  European journal of ophthalmology 20030301

• A systematic review of alternative therapies in the irritable bowel syndrome.

  Archives of internal medicine 20030210

• Oral desensitizing treatment in food allergy: clinical and immunological results.

  Alimentary pharmacology & therapeutics 20030201

• Nicorandil: albuterol-like or cromolyn-like?

  Critical care medicine 20030201

• Gastric hypersecretion associated to iodoacetamide-induced mild gastritis in mice.

  Naunyn-Schmiedeberg's archives of pharmacology 20030201

• Asthma prevalence and drug prescription in asthmatic children.

  European annals of allergy and clinical immunology 20030201

• Preparation and evaluation of a liposomal formulation of sodium cromoglicate.

  International journal of pharmaceutics 20030130

• Mast cells mediate the microvascular inflammatory response to systemic hypoxia.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030101

• Pycnogenol inhibits the release of histamine from mast cells.

  Phytotherapy research : PTR 20030101

• Long-term management of asthma.

  Indian journal of pediatrics 20030101

• Lung deposition in cystic fibrosis patients using an ultrasonic or a jet nebulizer.

  Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20030101

• Comparison of the efficacy and tolerability of topically administered azelastine, sodium cromoglycate and placebo in the treatment of seasonal allergic conjunctivitis and rhino-conjunctivitis.

  Current medical research and opinion 20030101

• Inhaled sodium cromoglycate for asthma in children.

  The Cochrane database of systematic reviews 20030101

• Evaluation of parental preference for the treatment of asthmatic children aged 6 to 11 years with oral montelukast or inhaled cromolyn: a randomized, open-label, crossover study.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20030101

• [Study of biopharmaceutic characteristics of cromoglycate eye drops].

  Medicina (Kaunas, Lithuania) 20030101

• [Longitudinal study of children with bronchopulmonary dysplasia treated with disodium cromoglycate].

  Medycyna wieku rozwojowego 20030101

• Inhalation and deposition of nebulized sodium cromoglycate in two different particle size distributions in children with asthma.

  Pediatric pulmonology 20021101

• Long-term management of asthma in children: effectiveness of inhaled corticosteroids compared to other medications.

  The Journal of allergy and clinical immunology 20021101

• Sodium cromoglycate and doxantrazole are oxygen radical scavengers.

  The European respiratory journal 20021001

• A comparison of the efficacy and tolerability of olopatadine hydrochloride 0.1% ophthalmic solution and cromolyn sodium 2% ophthalmic solution in seasonal allergic conjunctivitis.

  Clinical therapeutics 20021001

• The role of sodium cromolyn in treatment of paraquat-induced pulmonary fibrosis in rat.

  Pharmacological research 20020901

• [Enhancing effects of ion-pair complexes on skin permeation of cromolyn in vitro].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020901

• Mast cells as a target of rheumatoid arthritis treatment.

  Japanese journal of pharmacology 20020901

• Inhaled sodium cromoglycate in children with asthma.

  Thorax 20020801

• In vitro deposition of the respirable fraction of dry powder inhalations determined by laser diffractometry and inertial impaction.

  Die Pharmazie 20020801

• Water dynamics in channel hydrates investigated using H/D exchange.

  International journal of pharmaceutics 20020725

• Fluticasone for the treatment of symptomatic bronchial asthma in children treated with sodium cromogylate--a prospective, randomised trial.

  European journal of medical research 20020628

• [Exercise-induced asthma. Not a reason to be benched].

  MMW Fortschritte der Medizin 20020627

• Management of suspected acute viral upper respiratory tract infection in children with intranasal sodium cromoglicate: a randomised controlled trial.

  Lancet (London, England) 20020622

• Generalized bullae in an infant.

  Archives of dermatology 20020601

• Balancing safety and efficacy in the treatment of pediatric asthma.

  The Journal of allergy and clinical immunology 20020601

• (S)nifty treatment for pollen allergies.

  Health news (Waltham, Mass.) 20020601

• One-year trial on safety and normal linear growth with flunisolide HFA in children with asthma.

  Clinical pediatrics 20020601

• Allergic rhinitis remains an important disease.

  The Journal of the American Osteopathic Association 20020601

• Improved strategies and new treatment options for allergic rhinitis.

  The Journal of the American Osteopathic Association 20020601

• Efficacy and patient satisfaction with cromolyn sodium nasal solution in the treatment of seasonal allergic rhinitis: a placebo-controlled study.

  Clinical therapeutics 20020601

• The combination of nebulized sodium cromoglycate and salbutamol in the treatment of moderate-to-severe asthma in children.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20020601

• Airway hyperresponsiveness to adenosine induced by lipopolysaccharide in Brown Norway rats.

  British journal of pharmacology 20020501

• Nebulized budesonide inhalation suspension compared with cromolyn sodium nebulizer solution for asthma in young children: results of a randomized outcomes trial.

  Pediatrics 20020501

• Relative lung and systemic bioavailability of sodium cromoglycate inhaled products using urinary drug excretion post inhalation.

  Biopharmaceutics & drug disposition 20020501

• Floating a metered-dose inhaler is not an accurate measure of remaining medicine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020501

• Ischaemic preconditioning and mast cell histamine release: microdialysis of isolated rat hearts.

  Pharmacological research 20020501

• Effect of interventions during acute respiratory syncytial virus bronchiolitis on subsequent long term respiratory morbidity.

  The Pediatric infectious disease journal 20020501

• Management of allergic and nonallergic rhinitis.

  Evidence report/technology assessment (Summary) 20020501

• Perinatal immunomodulation.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20020501

• Interaction of S100 proteins with the antiallergic drugs, olopatadine, amlexanox, and cromolyn: identification of putative drug binding sites on S100A1 protein.

  Biochemical and biophysical research communications 20020412

• Use of intranasal cromolyn sodium for allergic rhinitis.

  Mayo Clinic proceedings 20020401

• Inhaled sodium cromoglycate in children with asthma.

  Thorax 20020301

• Medical management of Cronkhite-Canada syndrome.

  Southern medical journal 20020201

• Efficacy and safety of inhaled steroid and cromone treatment in school-age children: a randomized pragmatic pilot study.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20020201

• The effect of cosolvents on the formulation of nanoparticles from low-molecular-weight poly(l)lactide.

  AAPS PharmSciTech 20020201

• Assessment of the relationship between hyperalgesia and peripheral inflammation in magnesium-deficient rats.

  Life sciences 20020118

• From khellin to sodium cromoglycate--a tribute to the work of Dr. R. E. C. Altounyan (1922-1987).

  Die Pharmazie 20020101

• The effect of disodium cromoglycate, budesonide, and cyclosporin A on interleukin-4, interleukin-5, and interleukin-13 secretions in Der p I-stimulated T cells from house dust mite-sensitive atopic and nonatopic individuals.

  Allergy and asthma proceedings 20020101

• Topical treatment of pyoderma gangraenosum.

  Dermatology (Basel, Switzerland) 20020101

• Single dose of ketotifen fumarate .025% vs 2 weeks of cromolyn sodium 4% for allergic conjunctivitis.

  Advances in therapy 20020101

• Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion.

  American journal of respiratory medicine : drugs, devices, and other interventions 20020101

• Determination of sodium cromoglycate in human plasma by liquid chromatography-mass spectrometry in the turbo ion spray mode.

  Journal of chromatography. B, Biomedical sciences and applications 20011225

• Reasons for and costs of hospitalization for pediatric asthma: a prospective 1-year follow-up in a population-based setting.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20011201

• [Inhalation therapy].

  Annales de medecine interne 20011201

• [Effects of roxithromycin on proliferation and activation of mast cells].

  The Japanese journal of antibiotics 20011201

• Sodium cromoglycate in asthma.

  Thorax 20011101

• Therapy choices beyond antihistamines. Vasomotor rhinitis.

  Advance for nurse practitioners 20011101

• [Inhaled corticosteroid therapy in childhood asthma].

  Nihon rinsho. Japanese journal of clinical medicine 20011001

• Effect of specific immunotherapy versus loratadine on serum adhesion molecules.

  Allergie et immunologie 20011001

• Inhaled sodium cromoglycate in the management of asthma: should it be consigned to history?

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010901

• Sodium cromoglycate attenuates pulmonary inflammation without influencing bronchial responsiveness in healthy subjects exposed to organic dust.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010901

• [Sodium cromoglycate in the treatment of food hypersensitivity in children under 3 years of age].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010901

• Antiallergic/antiasthmatic effect of novel antiallergic hexapeptide-95/220 in various experimental models.

  Indian journal of experimental biology 20010901

• Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice.

  The Journal of pharmacology and experimental therapeutics 20010801

• Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain.

  Pediatric research 20010801

• Asthma symptoms, morbidity, and antiinflammatory use in inner-city children.

  Pediatrics 20010801

• Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthma.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010801

• [Exercise-induced asthma. The spray belongs in the 'athletic shoe'].

  MMW Fortschritte der Medizin 20010719

• Sodium cromoglycate in the management of chronic or recurrent enterocolitis in patients with Hirschsprung's disease.

  Journal of pediatric surgery 20010701

• A novel pharmacologic action of glucocorticosteroids on leukotriene C4 catabolism.

  The Journal of allergy and clinical immunology 20010701

• Inhaled sodium cromoglycate.

  Thorax 20010701

• The necessity for dual food intake to provoke food-dependent exercise-induced anaphylaxis (FEIAn): a case report of FEIAn with simultaneous intake of wheat and umeboshi.

  The Journal of allergy and clinical immunology 20010601

• Time to consign cromoglycate to history?

  Thorax 20010601

• Asthma in the hospitalized obstetrical patient.

  Clinical reviews in allergy & immunology 20010601

• The efficacy and safety of asthma medications during pregnancy.

  Seminars in perinatology 20010601

• Antihistamines and serum adhesion molecule levels.

  Allergie et immunologie 20010601

• Comparison of the cost-effectiveness of budesonide and sodium cromoglycate in the management of childhood asthma in everyday clinical practice.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010501

• [Color reactions for identification of sodium cromoglycate].

  Die Pharmazie 20010501

• Disodium cromoglycate inhibits production of immunoglobulin E.

  Immunopharmacology and immunotoxicology 20010501

• [Preventive monotherapy with montelukast versus DNCG in children with mild asthma. Results of and exploratory pilot study].

  Pneumologie (Stuttgart, Germany) 20010501

• Management of pyoderma gangrenosum.

  Hospital practice (1995) 20010415

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• Sodium cromoglycate in childhood asthma.

  Thorax 20010401

• Impact of inhaled antiinflammatory therapy on hospitalization and emergency department visits for children with asthma.

  Pediatrics 20010401

• Pyrazolopyrimidines: synthesis, effect on histamine release from rat peritoneal mast cells and cytotoxic activity.

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  Neuroscience 20010101

• Role of mast cells in zymosan-induced peritoneal inflammation in Balb/c and mast cell-deficient WBB6F1 mice.

  Journal of leukocyte biology 20010101

• Ultrasonic nebulization system for respiratory drug delivery.

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  The European respiratory journal 20010101

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• Substance P may attenuate gastric hyperemia by a mast cell-dependent mechanism in the damaged gastric mucosa.

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• Disodium cromoglycate does not prevent terbutaline-induced desensitization of beta 2-adrenoceptor-mediated cardiovascular in vivo functions in human volunteers.

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