15883-20-2 | 2',6'-Pipecoloxylidide

Packsize	Purity	Availability	Price	Discounted Price
25g	96%	in stock	$17.00	$12.00
100g	96%	in stock	$43.00	$30.00

Description

• Catalog Number: AA81325
• Chemical Name: 2',6'-Pipecoloxylidide
• CAS Number: 15883-20-2
• Molecular Formula: C14H20N2O
• Molecular Weight: 232.3214
• MDL Number: MFCD01701244
• SMILES: O=C(C1CCCCN1)Nc1c(C)cccc1C

Computed Properties

• Complexity: 257
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• Undefined Atom Stereocenter Count: 1
• XLogP3: 2.3

Literature

• Population pharmacokinetic analysis of ropivacaine and its metabolite 2',6'-pipecoloxylidide from pooled data in neonates, infants, and children.

  British journal of anaesthesia 20110901

• Pharmacokinetics of ropivacaine in patients with chronic renal failure.

  British journal of anaesthesia 20110401

• Effects of premedication medicines on the formation of the CYP3A4-dependent metabolite of ropivacaine, 2', 6'-Pipecoloxylidide, on human liver microsomes in vitro.

  Basic & clinical pharmacology & toxicology 20060201

• Nonaromatic hydroxylation of bupivacaine during continuous epidural infusion in man.

  Journal of biochemical and biophysical methods 20030829

• Determination of bupivacaine and metabolites in rat urine using capillary electrophoresis with mass spectrometric detection.

  Electrophoresis 20030701

• Regional transport and metabolism of ropivacaine and its CYP3A4 metabolite PPX in human intestine.

  The Journal of pharmacy and pharmacology 20030701

• Pharmacokinetics of ropivacaine in uremic and nonuremic patients after axillary brachial plexus block.

  Anesthesia and analgesia 20030201

• Effect of ciprofloxacin on the pharmacokinetics of ropivacaine.

  European journal of clinical pharmacology 20030201

• Synthesis and structure-activity relationships of potential anticonvulsants based on 2-piperidinecarboxylic acid and related pharmacophores.

  European journal of medicinal chemistry 20010301

• Acute cardiovascular and central nervous system toxicity of bupivacaine and desbutylbupivacaine in the rat.

  Acta anaesthesiologica Scandinavica 19920201